Danny McAuley

      Professor Danny McAuley

      Clinical Professor

      Phone: 028 90635794, +44 (0)28 9097 6385

      For media contact email comms.office@qub.ac.uk
      or call +44(0)2890 973091.

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      Interests

      Prof Danny McAuley is Professor and Consultant in Intensive Care Medicine at the Royal Victoria Hospital and Queen’s University of Belfast.

      He is Co-Director of Research for the Intensive Care Society. His major research area is the acute respiratory distress syndrome.

      Research Statement

      Current research interests

      My major interest is acute lung injury (ALI). My research strategy in ALI is to investigate potential novel therapeutic agents in ALI in vitro, in vivo in a human LPS model of ALI and in phase 2 clinical trials to inform subsequent phase 3 clinical trials. My roles as the UK Intensive Care Society Co-Director of Research, the Irish Critical Care Trials group Chair and the NICRN (Critical Care) clinical lead, mean I am well placed to develop the novel therapeutic targets into phase 3 clinical trials. I am currently investigating the role of statins and keratinocyte growth factor in vitro, in the in vivo human LPS model and in early phase clinical trials in the prevention and treatment of ALI.

      I am currently investigating elafin and SLPI in vitro with a view to developing these agents as potential therapeutic agents for ALI.

      I am also interested in ion channel function in the clearance of pulmonary oedema in ALI as well as the pathophysiological role of matrix metalloproteinases (MMPs), oncostatin M and receptor for advanced glycation endproducts (RAGE) in ALI.

      My other research interests are vascular reactivity in critical illness, nosocomial MRSA and fungal infection, acute kidney injury, delirium in critical illness and interventions in patients undergoing major vascular surgery to avoid pulmonary complications.

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      Frequent Journals

      • Thorax

        ISSNs: 0040-6376, 1468-3296

        BMJ Publishing Group Ltd and British Thoracic Society

        Scopus rating (2015): SJR 3.65 SNIP 2.326

        Journal

      • American Journal of Respiratory and Critical Care Medicine

        ISSNs: 1073-449X

        Additional searchable ISSN (Electronic): 1535-4970

        American Thoracic Society

        Scopus rating (2015): SJR 5.832 SNIP 3.326

        Journal

      • Critical Care

        ISSNs: 1466-609X, 1364-8535

        Springer Science + Business Media

        Scopus rating (2015): SJR 2.002 SNIP 1.579

        Journal

      • Critical Care Medicine

        ISSNs: 0090-3493

        Lippincott Williams and Wilkins

        Scopus rating (2015): SJR 3.748 SNIP 2.651

        Journal

      • Intensive Care Medicine

        ISSNs: 0342-4642

        Additional searchable ISSN (Electronic): 1432-1238

        Springer Verlag

        Scopus rating (2015): SJR 3.765 SNIP 2.528

        Journal

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