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      Interests

      For more information on Denise Fitzergerald's research use the link below

      http://www.qub.ac.uk/research-centres/CentreforInfectionandImmunity/Research/ResearchGroups/TheFitzgeraldGroup/

      Research Statement

      The Fitzgerald lab is a new NeuroImmunology research group at QUB with a particular focus on Multiple Sclerosis (MS), an immune-mediated, demyelinating disorder of the Central Nervous System (CNS).  The central goal of our research is to identify new strategies to treat MS and other inflammatory and demyelinating disorders.

      We are particularly interested in the process of myelin repair (remyelination) and aim to identify novel therapeutic targets to promote remyelination in MS. We also conduct a research programme on the pathogenesis of autoimmune inflammation. This programme mainly focuses on T cell biology with a view to identifying strategies to reduce disease activity in MS and other immune-mediated diseases. Our ongoing work investigates the fundamental biology of IL-27 and its therapeutic potential in inflammatory/autoimmune disease, with particular focus on Th1 and Th17 mediated inflammatory responses. My previous research has encompassed the role of TLRs in autoimmune inflammation and mucosal immunology.

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      Frequent Journals

      • Journal of immunology

        ISSNs: 0022-1767

        Additional searchable ISSN (Electronic): 1550-6606

        American Association of Immunologists

        Scopus rating (2016): SJR 3.368 SNIP 1.177

        Journal

      • Journal of Neuroimmunology

        ISSNs: 0165-5728

        Additional searchable ISSN (Electronic): 1872-8421

        Elsevier

        Scopus rating (2016): SJR 1.19 SNIP 0.782

        Journal

      • Open Autoimmunity Journal

        ISSNs: 1876-8946

        Bentham Science Publishers B.V.

        Scopus rating (2016): SJR 0.115 SNIP 2.149

        Journal

      • Journal of Neuroinflammation

        ISSNs: 1742-2094

        Additional searchable ISSN (Electronic): 1742-2094

        BioMed Central

        Scopus rating (2016): SJR 2.2 SNIP 1.22

        Journal

      • European Journal of Immunology

        ISSNs: 0014-2980

        Additional searchable ISSN (Electronic): 1521-4141

        Wiley-VCH Verlag

        Scopus rating (2016): SJR 2.47 SNIP 0.935

        Journal

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