Fiona Furlong
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      Research Interests

      Dr Fiona Furlong graduated in 1998 with an honours B.Sc. degree in Pharmacology from University College Dublin, and completed her Ph.D. in mammary gland cell biology in 2003.  Following on from a short post-doctoral position, researching diabetic nephropathy, Dr Furlong once again focused on cancer biology and in 2008, Dr Furlong was awarded the prestigious career development research fellowship from the Irish Cancer Society.  Since then, her research has focused on understanding the molecular mechanisms of chemoresistance in ovarian cancer.  In 2012, Dr Furlong joined the School of Pharmacy, QUB, as a Lecturer of Pharmacology, where she is currently researching the underlying mechanism of action of a number of candidate microRNAs in diseased cells and developing biomarkers of chemoresistance.

      Research Statement

      MicroRNAs were first described in 1993 and have since been developed as biomarkers and therapies for various diseases.  My research has contributed to this field in which we led the discovery that the miR-433 microRNA mediates chemoresistance and poor outcomes for patients with ovarian cancer.  We are centrally interested in interrogating the fundamental biological role of microRNAs in cells so that we can better understand disease pathology resulting from aberrant microRNA expression.  This is an exciting new field of research in which we have only described the tip of the iceberg in terms of microRNA functions.  This research has been funded by the Irish Cancer Society and the Health Research Board of Ireland.

      Frequent Journals

      • The FASEB Journal

        ISSNs: 0892-6638

        Additional searchable ISSN (Electronic): 1530-6860

        FASEB

        Scopus rating (2015): SJR 2.775 SNIP 1.18

        Journal

      • Journal of the American Society of Nephrology

        ISSNs: 1046-6673

        Additional searchable ISSN (Electronic): 1533-3450

        American Society of Nephrology

        Scopus rating (2015): SJR 4.699 SNIP 2.443

        Journal

      • Human Pathology

        ISSNs: 0046-8177

        W.B. Saunders Ltd

        Scopus rating (2015): SJR 1.363 SNIP 1.096

        Journal

      • Clinical Cancer Research

        ISSNs: 1078-0432

        Additional searchable ISSN (Electronic): 1557-3265, 1078-0432

        AMER ASSOC CANCER RESEARCH

        Scopus rating (2015): SJR 5.314 SNIP 2.021

        Journal

      • Biochimica et biophysica acta

        ISSNs: 0006-3002

        Journal

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      Contribution to conference papers, events and activities

      ID: 61580