Research

Our Research

Fiona Furlong
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Research Interests

Dr Fiona Furlong graduated in 1998 with an honours B.Sc. degree in Pharmacology from University College Dublin, and completed her Ph.D. in mammary gland cell biology in 2003.  Following on from a short post-doctoral position, researching diabetic nephropathy, Dr Furlong once again focused on cancer biology and in 2008, Dr Furlong was awarded the prestigious career development research fellowship from the Irish Cancer Society.  Since then, her research has focused on understanding the molecular mechanisms of chemoresistance in ovarian cancer.  In 2012, Dr Furlong joined the School of Pharmacy, QUB, as a Lecturer of Pharmacology, where she is currently researching the underlying mechanism of action of a number of candidate microRNAs in diseased cells and developing biomarkers of chemoresistance.

Research Statement

MicroRNAs were first described in 1993 and have since been developed as biomarkers and therapies for various diseases.  My research has contributed to this field in which we led the discovery that the miR-433 microRNA mediates chemoresistance and poor outcomes for patients with ovarian cancer.  We are centrally interested in interrogating the fundamental biological role of microRNAs in cells so that we can better understand disease pathology resulting from aberrant microRNA expression.  This is an exciting new field of research in which we have only described the tip of the iceberg in terms of microRNA functions.  This research has been funded by the Irish Cancer Society and the Health Research Board of Ireland.

Frequent Journals

  • The FASEB Journal

    ISSNs: 0892-6638, 0892-6638

    Additional searchable ISSN (Electronic): 1530-6860

    FASEB

    Scopus rating (2015): SJR 2.775 SNIP 1.18

    Journal

  • Journal of the American Society of Nephrology

    ISSNs: 1046-6673

    Additional searchable ISSN (Electronic): 1533-3450, 1533-3450

    American Society of Nephrology

    Scopus rating (2015): SJR 4.699 SNIP 2.443

    Journal

  • Human Pathology

    ISSNs: 0046-8177, 0046-8177

    W.B. Saunders Ltd

    Scopus rating (2015): SJR 1.363 SNIP 1.096

    Journal

  • Clinical Cancer Research

    ISSNs: 1078-0432, 1078-0432

    Additional searchable ISSN (Electronic): 1557-3265, 1078-0432

    AMER ASSOC CANCER RESEARCH

    Scopus rating (2015): SJR 5.314 SNIP 2.021

    Journal

  • Biochimica et biophysica acta

    ISSNs: 0006-3002

    Journal

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Contribution to conference papers, events and activities

ID: 61580