A suite of EU-OSHA research reports (2011–2014), including economic modelling of work-related stress and systematic reviews of workplace health promotion, were used as core evidence and campaign materials for the Healthy Workplaces Manage Stress campaign (2014–2015). The reports informed campaign messaging, policy guidance, stakeholder engagement activities and EU-level advocacy on psychosocial risk prevention across Member States. This work contributed to strengthening the economic and public health case for organisational investment in stress prevention and mental health promotion.