Activity: Talk or presentation types › Invited talk
Description
Background information about the talk: Bringing together epidemiologic methods and design with histological and molecular tumour profiling, my research aims to identify mechanisms linking dietary and lifestyle factors with prostate cancer risk and progression. My group works collaboratively with existing studies of prostate cancer around the globe, alongside establishing new resources within existing registries by harnessing developments in ‘omics profiling of archival tissue specimens. In this talk I will share some findings from our ongoing research into the mechanistic underpinnings of the epidemiological association between statin medication use and lower risk of aggressive and fatal prostate cancer. Our work considers how certain molecular subgroups of prostate tumours may be more or less susceptible to statin-mediated effects, and identifies some preliminary evidence for the dysregulated molecular pathways behind the observed epidemiological associations.