In December 2021, the Global Observatory held an online workshop titled A Question of Life: Human Dignity, Reproductive Rights, and Abortion Politics. This event explored political struggles over the limits of life by focusing on abortion politics across different national contexts, with a special focus on the recent liberalization of abortion rights across Latin American countries. This convening was a response to the then-recent decriminalization of abortion in Mexico, but throughout, the United States served as an implicit counterpoint, as another liberal democracy that was moving in the opposite direction. Indeed, the event anticipated the overturn of decades of precedent set by the Roe v. Wade decision, which came six months after A Question of Life with the Supreme Court’s decision in Dobbs v. Jackson Women’s Health Organization. In the wake of this decision, we asked several of the panelists from A Question of Life to respond to a series of prompts designed to shed light on Dobbs by comparing the framings of abortion politics and constellations of rights and responsibilities across their respective countries of focus. The result helps us understand how different cultural and historical contexts have shaped the abortion debate across different countries and produced different settlements between state obligations to protect life and the right to receive an abortion.