Characterisation of morphological differences in well-differentiated nasal epithelial cell cultures

  • Helen Groves (Creator)
  • Hong Guo Parke (Creator)
  • Lindsay Broadbent (Creator)
  • Michael Shields (Creator)
  • Ultan Power (Creator)

Dataset

Description

Data set underpinning Groves, H., Parke, H. G., Broadbent, L., Shields, M., and Power, U. in 'Characterisation of morphological differences in well-differentiated nasal epithelial cell cultures.'' PLoS One

We collected nasal epithelial cells from 41 newborn infants (23 term, 18 preterm) within 5 days of birth. Repeat sampling was achieved for 24 infants (13 term, 11 preterm) at a median age of 12.5 months. Morphologically- and physiologically-authentic well-differentiated primary paediatric nasal epithelial cell (WD-PNEC) cultures were generated and characterised using light microscopy and immunofluorescence. Results detail clinical characteristics of recruited infants and microscopy findings for cilia and goblet cell proportions of generated well-differentiated nasal epithelial cell cultures from Preterm and Term infants at birth and one-year.

Dataset documents are labelled according to figures for article as linked.
Date made available25 Oct 2018
PublisherQueen's University Belfast
Date of data production2014 - 2018

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