Hydroxyapatite-binding plasma proteins in Age-related macular degenaration

  • Swati Arya (Creator)
  • Eszter Emri (Creator)
  • Silvia A Synowsky (Creator)
  • Sally L Shirran (Creator)
  • Neda Barzegar-Befroeid (Creator)
  • Tunde Peto (Creator)
  • Catherine H Botting (Creator)
  • Imre Lengyel (Creator)
  • Alan J Stewart (Creator)



This project identifies and quantitates Hydroxyapatite binding proteins (HAP) in plasma genotyped for complement factor H (CFH) polymorphism in late stage age-related macular degeneration (AMD) patients by sequential window acquisition of all theoretical mass spectra (SWATH). This study provides insights into factors contributing to the formation of sub-retinal pigment epithelial (RPE) deposits.

Dataset is in The PRIDE PRoteomics IDEntifications (PRIDE) Archive database. Published article appeared in Journal of Experimental Eye Research.
Date made available28 Mar 2018
PublisherUniversity of St Andrews
Date of data production15 Nov 2018

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