Identification of neuropeptide encoding transcripts, neuropeptide processing enzymes and neuropeptide F/Y G-protein coupled receptors in Fasciola hepatica

Dataset

Description

Presented in this dataset are the high confidence neuropeptide-encoding transcripts identified in Fasciola hepatica, complete with signal peptide, neuropeptide, and basic cleavage site identification. High confidence in this context is defined as presence of common neuropeptide motifs and homology to previously identified neuropeptides. Low confidence neuropeptide encoding transcripts were also identified with these sequences lacking homology to previously discovered neuropeptides. Neuropeptide processing enzymes prohormone convertase 2, peptidylglycine alpha-hydroxylating monooxygenase and peptidyl-alpha-hydroxyglycine alpha-amidating lyase are also listed. In efforts to identify a cognate receptor for Fh-NPY-1, seven putative neuropeptide F/Y G-protein coupled receptors were identified and targeted for RNA interference.
Date made availableOct 2020
PublisherQueen's University Belfast
Date of data production01 Jun 2020

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