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Meeting abstract

314: BCLAF1; a multi-faceted protein involved DNA repair, apoptosis and autophagy

Barros, E., Savage, K. S. & Harkin, D. P., Jul 2014, In : European Journal of Cancer. 50, Supp 5, p. S75 1 p.

Research output: Contribution to journalMeeting abstract

482 POSTER c-FLIP regulates the interaction between interferon-gamma and doxorubicin in breast cancer cells

Rogers, K., Thomas, M., Johnston, P. & Longley, D., Nov 2006, In : European Journal of Cancer Supplements. 4, 12, p. 147 1 p.

Research output: Contribution to journalMeeting abstract

7 Citations (Scopus)

Abstract 1905: Defining a therapeutic classification of breast cancer by actionable targets

Salto-Tellez, M., Boyle, D. P., McArt, D., Irwin, G., Wilhelm-Benartzi, C. C., Lloe, T. G., Minter, M., McQuaid, S., Mullan, P., Kennedy, R. D., Hamilton, P. & Harkin, D. P., 01 Oct 2014, In : Cancer Research. 74, 19 (Suppl), 1905.

Research output: Contribution to journalMeeting abstract

Abstract OT3-02-07: Neo-DDRD: A biomarker-driven neoadjuvant feasibility study in breast cancer

McIntosh, SA., Parkes, EE., James, CR., Lioe, T., Lowry, K., Keating, KE., Khambata-Ford, S. & Kennedy, RD., 15 Feb 2016, In : Cancer Research. 76, 4 Supplement, OT3-02-07.

Research output: Contribution to journalMeeting abstract

Activation of and dependence on ataxia telangiectasia mutated kinase in PTEN-deficient tumor cells

McCabe, N., Walker, S. M., Goffard, N., Wikstrom, K., Greenan, C., McLean, E., McDyer, F. A., Keating, K. E., James, I., Harrison, T., Mullan, P. B., Harkin, D. P., Chen, C. & Kennedy, R. D., 20 May 2012, In : Journal of Clinical Oncology. 30, 15, S, 1 p.

Research output: Contribution to journalMeeting abstract

Activin B functions downstream of BRCA1 in stem cell maintenance

Murray, M. M., Buckley, N. & Harkin, P., May 2010, In : Breast Cancer Research. 12, 1, p. S3 1 p.

Research output: Contribution to journalMeeting abstract

An evaluation of siRNA screening in identification of targets in PTEN deficient tumor cells

McCabe, N., Walker, S. M., Wikstrom, K., Greenan, C., McLean, E., Delaney, T., McCarthy, M., Cochrane, D., Wilson, C., Davison, T. S., McDyer, F. A., Jellema, G. L., Goffard, N., James, I., Harrison, T., Mullan, P. B., Harkin, D. P. & Kennedy, R. D., 20 May 2011, In : Journal of Clinical Oncology. 29, 15, 1 p.

Research output: Contribution to journalMeeting abstract

An exploration of men’s experiences of undergoing active surveillance for favourable-risk prostate cancer: a mixed methods study protocol

Ruane-McAteer, E., O'Sullivan, J., Porter, S. & Prue, G., Mar 2016, In : Psycho-oncology. 25, S1, p. 16-17 2 p.

Research output: Contribution to journalMeeting abstract

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2 Citations (Scopus)
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A phase I dose escalation multi-centre study of crizotinib (MET inhibitor) combined with binimetinib (MEK inhibitor) in patients with advanced solid tumours

Wilson, R., Dass, P. H., Van Schaeybroeck, S., Elez, E., Quinton, A., Jones, R., Houlden, J., Collins, L., Roberts, C., Love, S., Lawler, M., Di Nicolantonio, F., Grayson, M., Bardelli, A., Laurent=puig, P., Maughan, T., Tabernero, J., Peeters, M., Middleton, M. & Rolfo, C., Nov 2018, In : European Journal of Cancer. 103, Suppl 1, p. e140-e141

Research output: Contribution to journalMeeting abstract

A preoperative clinical staging and metabolic imaging model to predict prognosis in early-stage esophageal adenocarcinoma

Turkington, R. C., Blayney, J. K., Jalil, A., Goody, R. B., Papafili, A., Henderson, C., McManus, D., Johnston, P., Kennedy, R. & Eatock, M. M., 20 Jan 2014, In : Journal of Clinical Oncology. 32, 3 (Suppl), 1 p.

Research output: Contribution to journalMeeting abstract

A PROGNOSTIC SIGNATURE FOR PTEN-DEFICIENT GLIOBLASTOMAS

Gonda, D. D., Li, J., McCabe, N., Walker, S., Goffard, N., Wikstrom, K., McLean, E., Greenan, C., Delaney, T., McCarthy, M., McDyer, F., Keating, K. E., James, I. F., Harrison, T., Mullan, P., Harkin, D. P., Carter, B. S., Kennedy, R. & Chen, C. C., Oct 2012, In : Journal of Neuro-Oncology. 14, 6, p. 98 1 p.

Research output: Contribution to journalMeeting abstract

A PROSPECTIVE PROTOCOL FOR SIMULTANEOUS GENOMIC TESTING IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

Lopez-Rios, F., Conde, E., Angulo, B., Martinez, R., Mcgready, C., O'Hara, G., Anderson, N., Maxwell, P. & Salto-Tellez, M., Nov 2013, In : Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 8, p. S1074-S1074 1 p.

Research output: Contribution to journalMeeting abstract

Arrested Differentiation in Acute Myeloid Leukemia (AML) with Silenced Ankyrin Repeat and SOCS Box Protein 3 (ASB3) Expression

Logan, G., Rapin, N., Porse, B. T., Percy, M. J. & Mills, K. I., 16 Nov 2012, In : Blood. 120, 21, p. - 2 p.

Research output: Contribution to journalMeeting abstract

A sector-based postimplant dosimetric comparison of sagittal and axial ultrasound-guided source placement during I-125 permanent prostate brachytherapy

Yoosuf, A. B. M., Mitchell, D. M., Byrne, M. M., Flynn, M. A., Napier, E., Jain, S. & Workman, G., 01 Feb 2014, In : Journal of Clinical Oncology. 32, 4 Suppl, 262.

Research output: Contribution to journalMeeting abstract

A small interfering ribonucleic acid-based approach to characterize brain tumor resistance to radiation therapy

Chen, C. C., Kennedy, R. & D'Andrea, A., Aug 2006, In : Neurosurgery. 59, 2, p. 485-485 1 p.

Research output: Contribution to journalMeeting abstract

Association between ColDx assay result and recurrence-free interval in stage II colon cancer patients on CALGB (Alliance) 9581

Niedzwiecki, D., Frankel, W., Venook, A. P., Ye, X., Friedman, P. N., Goldberg, R. M., Mayer, R. J., Colacchio, T. A., Kennedy, R., Davison, T., O'Brien, E. J., Mulligan, J., Johnston, P. G., Harkin, D. P., Schilsky, R. L., Bertagnolli, M. M. & Innocenti, F., 20 Jan 2014, In : Journal of Clinical Oncology. 32, 3 (suppl), 1 p.

Research output: Contribution to journalMeeting abstract

Association of a DNA damage response deficiency (DDRD) assay with prognosis in resected esophageal and gastric adenocarcinoma

Turkington, R., Knight, L., Douglas, R., Blayney, J., Stevenson, L., McManus, D., McCavigan, A., Walker, S., Bornschein, J., McRae, S., Noble, F., Underwood, T., O'Neill, R., McQuaid, S., Arthur, K., James, J., Eatock, M., Harkin, D., Fitzgerald, R. C. & Kennedy, R., 01 May 2017, In : Journal of Clinical Oncology : official journal of the American Society of Clinical Oncology. 35, 15_suppl, p. 4026-4026 1 p., 4026.

Research output: Contribution to journalMeeting abstract

A subtype representing activated ATM signalling in PTEN-null tumours

McCabe, N., Walker, S., Goffard, N., Wikstrom, K., Greenan, C., McDyer, F., Hill, L., Deharo, S., Harkin, D. P. & Kennedy, R., Oct 2011, In : European Journal of Cancer. 47, 4, p. S23 1 p.

Research output: Contribution to journalMeeting abstract

Automated tumour annotation and analysis for molecular pathology using TissueMark (R)

Hamilton, P., Wang, Y., McCleary, D., Diamond, J., Regan, E., Montgomery, N., Tunstall, J., Boyle, D., Loughrey, M. & Salto-Tellez, M., 14 Aug 2014, In : Virchows Archiv. 465, 1, p. S329-S329 1 p.

Research output: Contribution to journalMeeting abstract

Bladder cancer diagnostic algorithms in hematuria populations.

Stevenson, M., Reid, C., Duggan, B., Ruddock, M. & Williamson, K. E., 15 Apr 2013, In : Cancer Research. 73, 8, 1 p.

Research output: Contribution to journalMeeting abstract

BRCA1 as a regulator of global cell metabolism - identifying functional targets through integromic analysis

Powell, A., Savage, K. I. & Harkin, D. P., Jul 2014, In : European Journal of Cancer. 50, 5, p. S77 1 p.

Research output: Contribution to journalMeeting abstract

BRCA1 protein expression as a predictor of outcome following chemotherapy in sporadic epithelial ovarian cancer (EOC)

Carser, J. E., Quinn-O'Brien, J., Michie, C. O., McCluggage, W. G., Williams, A. R., Mullan, P., Gourley, C. M. & Harkin, P., 20 May 2009, In : Journal of Clinical Oncology. 27

Research output: Contribution to journalMeeting abstract

BRCA1 transcriptionally regulates genes associated with the basal breast cancer phenotype

Quinn, JE., James, CR., Gorskii, JJ., Mullan, PB. & Harkin, DP., 01 Nov 2006, In : Breast Cancer Research. 8, Suppl 2, p. S1 1 p., S4.

Research output: Contribution to journalMeeting abstract

Breaking DNA and killing cells with exotic types of radiation

Schettino, G., Timson, D. J., Currell, F. J. & Kavanagh, J. N., 2012, In : International Journal of Molecular Medicine. 30, p. S12-S12 1 p.

Research output: Contribution to journalMeeting abstract

Breast cancer outcomes following predictive BRCA testing in Northern Ireland

Hinds, G., Irwin, G., McFaul, L., Stewart, R., Morton, L., Savage, K. I., Morrison, P. J. & McIntosh, S. A., Jun 2016, In : Current Oncology. 23, 3, p. e298 P043.

Research output: Contribution to journalMeeting abstract

6 Citations (Scopus)

Ca2+-activated chloride currents in smooth muscle cells isolated from sheep urethra

Cotton, KD., Hollywood, MA., McHale, NG. & Thornbury, KD., May 1997, In : Journal of Physiology. 501P, p. P111-P112 2 p.

Research output: Contribution to journalMeeting abstract

Cabozantinib attenuates CXCL8-driven macrophage dependent migration and invasion of PTEN-deficient prostate cancer cells

Neisen, J. L., McCabe, N., Kennedy, R. D. & Waugh, D. JJ., 01 Jan 2015, In : Cancer Research. 75, 1 Suppl, A49.

Research output: Contribution to journalMeeting abstract

Cardiac hypertrophy and hypotension induced by systemic alpha(1B)-adrenergic receptor overactivity.

Zuscik, M., Chalothorn, D., Hellard, D., Waugh, D., Plow, E., Piascik, M. & Perez, D., 11 May 2000, In : The FASEB Journal. 14, 8, p. A1412-A1412 1 p.

Research output: Contribution to journalMeeting abstract

Cautionary tale of active surveillance in intermediate-risk patients: Overall and cause-specific survival in the Sunnybrook experience

Musunuru, H. B., Klotz, L., Vespirini, D., Zhang, L., Mamedov, A., Sethukavalan, P., Jethava, V., Yamamoto, T., Jain, S. & Loblaw, D. A., 01 Mar 2015, In : Journal of Clinical Oncology. 33, 7 Suppl, 163.

Research output: Contribution to journalMeeting abstract

CD44 Expression on prostate cancer cells correlates with adhesion to bone marrow endothelial cells.

Draffin, J. E., Hill, A., Johnston, P. G. & Waugh, D. J., 01 Dec 2003, In : Clinical Cancer Research. 9, 16, p. 6181S-6181S 1 p.

Research output: Contribution to journalMeeting abstract

CD44 regulates the expression of the cysteine protease Cathepsin K: implications for bone metastasis of breast cancer

Hill, A., McFarlane, S., Johnston, P. & Waugh, D., Nov 2006, In : EJC SUPPLEMENTS. 4, 12, p. 17-17 1 p.

Research output: Contribution to journalMeeting abstract

CGRP receptors on porcine arteries.

Waugh, D., Bockman, C. S., Smith, D. D. & Abel, P. W., 08 Mar 1996, In : The FASEB Journal. 10, 3, p. 4022-4022 1 p.

Research output: Contribution to journalMeeting abstract

CHALLENGE-UK: A UK cohort of the colon health and lifelong exercise change study: A phase III randomised control trial.

Brown, M., Yates, T., Forde, C., Adams, R., Booth, C., Courneya, K., Donnelly, M., O'Callaghan, C., Russell, A., Storey, D., Thomas, A., Wilson, R. & Coyle, V., Nov 2018, In : Journal of sports sciences. 36, S1, p. 22

Research output: Contribution to journalMeeting abstract

Characterization of a calcium-dependent chloride current in isolated sheep mesenteric lymphatic smooth muscle cells

Hollywood, MA., Toland, HM., Cotton, KD., Thornbury, KD. & McHale, NG., Dec 1997, In : Journal of Physiology. 505P, p. 96P-96P 1 p.

Research output: Contribution to journalMeeting abstract

Chemoprevention in BRCA1 Mutation Carriers—A Proof-of-Concept Study

Campbell, A., Savage, K., McIntosh, S. & Harkin, D., May 2016, In : Current Oncology. 23, 3, p. e290 1 p.

Research output: Contribution to journalMeeting abstract

C-kit-positive cells in lymphatic vessels

McCloskey, KD., Hollywood, MA., Thornbury, KD., Ward, SM. & McHale, NG., Nov 2000, In : Journal of Physiology. 528P, p. 11P-11P 1 p.

Research output: Contribution to journalMeeting abstract

ckit-positive cells in the guinea-pig bladder

McCloskey, KD. & Gurney, AM., Nov 2001, In : Journal of Physiology. 536, p. 95P-95P 1 p.

Research output: Contribution to journalMeeting abstract

Comparison of active surveillance with other treatment options for low-risk prostate cancer

Musunuru, H. B., Morton, G., Klotz, L., Vespirini, D., Cheung, P., Chung, H. T., Zhang, L., Mamedov, A., Sethukavalan, P., Jethava, V., D'Alimonte, L., Deabreu, A., Jain, S., Yamamoto, T. & Loblaw, D. A., 01 Mar 2015, In : Journal of Clinical Oncology. 33, 7 Suppl, 178.

Research output: Contribution to journalMeeting abstract

Conditional survival probability in patients with resected oesophageal adenocarcinoma receiving neoadjuvant chemotherapy

Turkington, R., Graham, D., Bannon, F., Noble, F., O'Neill, R., Blayney, J., Underwood, T., Kennedy, R. & Fitzgerald, R. C., 11 Oct 2017, In : Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 27, supp6, p. vi222 1 p.

Research output: Contribution to journalMeeting abstract

Open Access

Contribution of a penitrem A-sensitive current to the action potential in smooth muscle cells isolated from the sheep urethra

Hollywood, MA., Cotton, KD., Thornbury, KD. & McHale, NG., Jun 1998, In : Journal of Physiology. 509P, p. 28P-29P 2 p.

Research output: Contribution to journalMeeting abstract

Differential Expression of SHP-1 Levels in Chronic Phase and Advanced Disease CML and in AML Patients

Kaeda, J. S., Oberender, C., Neuman, D., Kim, T., Mills, K. I., Serra, A., Hemmati, P., Schleede, R., Overkamp, T., Ringel, F., Pretzsch, T., Turkmen, S., Schwarz, M., Arnold, R., Doerken, B. & le Coutre, P., 16 Nov 2012, In : Blood. 120, 21, p. - 2 p.

Research output: Contribution to journalMeeting abstract

Discovery of prognostic and predictive tissue biomarkers in patients with resectable esophageal cancer

MacGregor, T. P., Gillies, R. S., Sahgal, N., Chetty, R., Wang, L-M., Turkington, R. C., Maynard, N. D., Mchugh, P. J., Kennedy, R., Middleton, M. R. & Sharma, R. A., 20 Jan 2014, In : Journal of Clinical Oncology. 32, 3 (Suppl), 1 p.

Research output: Contribution to journalMeeting abstract

Distinct Chromosomal Alterations Segregate with SEPT6 Expression Levels in Leukaemia

Chatham, L. R., Todd, C. B., Hillan, K. J., Mills, K., Hall, P. A. & Russell, H., Mar 2012, In : Journal of Pathology. 226, p. S14-S14 1 p.

Research output: Contribution to journalMeeting abstract

DNA damage response deficiency signature predicts response to platinum-based therapy in ovarian cancer

Hill, L. A., Mulligan, J. M., Deharo, S., Keating, K. E., McDyer, F. A., Davison, T. S., Gourley, C., Harkin, D. P. & Kennedy, R. D., Sep 2013, In : European Journal of Cancer. 49, 2, p. S196-S196 1 p.

Research output: Contribution to journalMeeting abstract

Effects of the IP3-induced Ca2+ release modulator 2-aminoethoxydiphenylborate on calcium-activated currents in interstitial cells isolated from the rabbit urethra

Hollywood, MA., Sergeant, GP., McCloskey, KD., McHale, NG. & Thornbury, KD., Nov 2000, In : Journal of Physiology. 528P, p. 2P-3P 2 p.

Research output: Contribution to journalMeeting abstract

Epigenetic Silencing of BCL2, ETS1, IL27RA and DICER1 in Low-Risk MDS Patients

del Rey, M., O'Hagan, K., Dellett, M., Aibar, S., Colyer, H. A. A., Eugenia Alonso, M., Diez-Campelo, M., Armstrong, R. N., Sharpe, D. J., Gutierrez, N. C., Luis Garcia, J., de las Rivas, J., Mills, K. I. & Hernandez-Rivas, J. M., 16 Nov 2012, In : Blood. 120, 21, p. - 2 p.

Research output: Contribution to journalMeeting abstract

Fast sodium current in isolated lymphatic smooth muscle cells of the sheep

Hollywood, MA., Cotton, KD., Thornbury, KD. & McHale, NG., Sep 1996, In : Journal of Physiology. 495P, p. P98-P99 2 p.

Research output: Contribution to journalMeeting abstract