Research Output

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Review article
2020

Benefits and Risks of Primary Treatments for High-risk Localized and Locally Advanced Prostate Cancer: An International Multidisciplinary Systematic Review

Moris, L., Cumberbatch, M. G., Van den Broeck, T., Gandaglia, G., Fossati, N., Kelly, B., Pal, R., Briers, E., Cornford, P., De Santis, M., Fanti, S., Gillessen, S., Grummet, J. P., Henry, A. M., Lam, T. B. L., Lardas, M., Liew, M., Mason, M. D., Omar, M. I., Rouvière, O. & 12 others, Schoots, I. G., Tilki, D., van den Bergh, R. C. N., van Der Kwast, T. H., van Der Poel, H. G., Willemse, P. P. M., Yuan, C. Y., Konety, B., Dorff, T., Jain, S., Mottet, N. & Wiegel, T., May 2020, In : European Urology. 77, 5, p. 614-627 14 p.

Research output: Contribution to journalReview article

2019

Application of nanotechnology to target and exploit tumour associated proteases

Cogo, F., Williams, R., Burden, R. E. & Scott, C. J., 01 Nov 2019, In : Biochimie. 166, p. 112-131

Research output: Contribution to journalReview article

1 Citation (Scopus)

Mechanistic Modelling of Radiation Responses

McMahon, S. J. & Prise, K. M., 10 Feb 2019, In : Cancers. 11, 2, 23 p., 205.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
137 Downloads (Pure)
2018
Open Access
File
1 Citation (Scopus)
112 Downloads (Pure)

Bromodomain-containing proteins in prostate cancer

Urbanucci, A. & Mills, I. G., 15 Feb 2018, In : Molecular and Cellular Endocrinology. 462, Part A

Research output: Contribution to journalReview article

4 Citations (Scopus)

Consensus on molecular imaging and theranostics in prostate cancer

Fanti, S., Minozzi, S., Antoch, G., Banks, I., Briganti, A., Carrio, I., Chiti, A., Clarke, N., Eiber, M., De Bono, J., Fizazi, K., Gillessen, S., Gledhill, S., Haberkorn, U., Herrmann, K., Hicks, R. J., Lecouvet, F., Montironi, R., Ost, P., O'Sullivan, J. M. & 11 others, Padhani, A. R., Schalken, J. A., Scher, H. I., Tombal, B., van Moorselaar, R. J. A., Van Poppel, H., Vargas, H. A., Walz, J., Weber, W. A., Wester, H-J. & Oyen, W. J. G., 01 Dec 2018, In : Lancet Oncology. 19, 12, p. e696-e708 13 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer

Lawler, M., Alsina, D., Adams, R. A., Anderson, A. S., Brown, G., Fearnhead, N. S., Fenwick, S. W., Halloran, S. P., Hochhauser, D., Hull, M. A., Koelzer, V. H., McNair, A. G. K., Monahan, K. J., Näthke, I., Norton, C., Novelli, M. R., Steele, R. J. C., Thomas, A. L., Wilde, L. M., Wilson, R. H. & 2 others, Tomlinson, I. & Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative, 01 Jan 2018, In : Gut. 67, 1, p. 179-193 15 p.

Research output: Contribution to journalReview article

Open Access
File
27 Citations (Scopus)
112 Downloads (Pure)

Delivering modern, high-quality, affordable pathology and laboratory medicine to low-income and middle-income countries: a call to action

Horton, S., Sullivan, R., Flanigan, J., Fleming, K. A., Kuti, M. A., Looi, L. M., Pai, S. A. & Lawler, M., May 2018, In : Lancet. 391, 10133, p. 1953-1964

Research output: Contribution to journalReview article

29 Citations (Scopus)

FLIP as a therapeutic target in cancer

Humphreys, L., Espona-Fiedler, M. & Longley, D. B., Nov 2018, In : The FEBS Journal. 285, 22, p. 4104-4123 20 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

HER2 testing of gastro-oesophageal adenocarcinoma: a commentary and guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Committee

Wong, N. A. C. S., Amary, F., Butler, R., Byers, R., Gonzalez, D., Haynes, H. R., Ilyas, M., Salto-Tellez, M. & Taniere, P., 08 Feb 2018, In : Journal of Clinical Pathology.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions

Sayed, S., Cherniak, W., Lawler, M., Tan, S. Y., El Sadr, W., Wolf, N., Silkensen, S., Brand, N., Looi, L. M., Pai, S. A., Wilson, M. L., Milner, D., Flanigan, J. & Fleming, K. A., 14 Mar 2018, In : Lancet. 391, 10133, p. 1939-1952

Research output: Contribution to journalReview article

38 Citations (Scopus)

Multidisciplinary European Low Dose Initiative (MELODI): strategic research agenda for low dose radiation risk research

Kreuzer, M., Auvinen, A., Cardis, E., Durante, M., Harms-Ringdahl, M., Jourdain, J. R., Madas, B. G., Ottolenghi, A., Pazzaglia, S., Prise, K. M., Quintens, R., Sabatier, L. & Bouffler, S., Mar 2018, In : Radiation and Environmental Biophysics. 57, 1, p. 5-15

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
137 Downloads (Pure)

Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer

Montroni, I., Ugolini, G., Saur, N. M., Spinelli, A., Rostoft, S., Millan, M., Wolthuis, A., Daniels, I. R., Hompes, R., Penna, M., Fürst, A., Papamichael, D., Desai, A. M., Cascinu, S., Gèrard, J. P., Myint, A. S., Lemmens, V. E. P. P., Berho, M., Lawler, M., De Liguori Carino, N. & 8 others, Potenti, F., Nanni, O., Altini, M., Beets, G., Rutten, H., Winchester, D., Wexner, S. D. & Audisio, R. A., 01 Nov 2018, In : European Journal of Surgical Oncology. 44, 11, p. 1685-1702 18 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

The impact of transcription on metabolism in prostate and breast cancers

Poulose, N., Mills, I. G. & Steele, R. E., 01 Sep 2018, In : Endocrine-Related Cancer. 25, 9, p. R435-R452 8 p.

Research output: Contribution to journalReview article

Open Access
File
2 Citations (Scopus)
93 Downloads (Pure)

What are the origins and relevance of spontaneous bladder contractions? ICI-RS 2017

Drake, M. J., Fry, C. H., Hashitani, H., Kirschner-Hermanns, R., Rahnama'i, M. S., Speich, J. E., Tomoe, H., Kanai, A. J. & McCloskey, K. D., 23 Jan 2018, In : Neurourology and Urodynamics.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2017
Open Access
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4 Citations (Scopus)
242 Downloads (Pure)

A systematic review of outcomes following Stereotactic Ablative Radiotherapy in the treatment of early stage primary lung cancer. SABR for early stage NSCLC

Murray, P., Franks, K. & Hanna, G., 17 Feb 2017, In : British Journal of Radiology. 90, 1071, p. 1 45 p., 20160732.

Research output: Contribution to journalReview article

338 Citations (Scopus)

Cardiotoxicity Following Cancer Treatment.

Walls, G., Lyon, A. R., Harbinson, M. & Hanna, G., 01 Jan 2017, In : Ulster Medical Journal. 86, 1, p. 3-9

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
80 Downloads (Pure)

Epigenetics in Myeloproliferative Neoplasms

McPherson, S., McMullin, M. F. & Mills, K., 25 Aug 2017, In : Journal of Cellular and Molecular Medicine. 8 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
227 Downloads (Pure)

Low-dose radiation-induced risk in spermatogenesis

Fukunaga, H., Butterworth, K. T., Yokoya, A., Ogawa, T. & Prise, K. M., 2017, In : International journal of radiation biology. 93, 12, p. 1291-1298 8 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
185 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
157 Downloads (Pure)

Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges

MErCuRIC consortium, 04 Apr 2017, In : Nature reviews. Clinical oncology. 14, 9

Research output: Contribution to journalReview article

51 Citations (Scopus)

The Potential of Targeting DNA Repair Deficiency in Acute Myeloid Leukemia

Crean, C., Mills, K. I. & Savage, K. I., 28 Jul 2017, In : Journal of Cancer Therapy. 8, p. 691-698 8 p.

Research output: Contribution to journalReview article

Open Access
File
1194 Downloads (Pure)

Tissue-based next generation sequencing: application in a universal healthcare system

Hynes, S. O., James, J. A., Maxwell, P. & Salto-Tellez, M., 28 Feb 2017, In : British Journal of Cancer. 116, 5, p. 553-560 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
148 Downloads (Pure)
2016

Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control

Vohhodina, J., Harkin, D. P. & Savage, K. I., Oct 2016, In : Wiley interdisciplinary reviews. RNA. 7, 5, p. 604-619

Research output: Contribution to journalReview article

12 Citations (Scopus)

Fiducial Marker Guided Prostate Radiotherapy: A Review

O'Neill, A. GM., Jain, S., Hounsell, A. R. & O'Sullivan, J. M., 23 Sep 2016, In : British Journal of Radiology. 89

Research output: Contribution to journalReview article

Open Access
File
18 Citations (Scopus)
361 Downloads (Pure)

Gold nanoparticles for cancer radiotherapy: a review.

Haume, K., Rosa, S., Grellet, S., Śmiałek, M. A., Butterworth, K. T., V. Solov’yov, A., Prise, K. M., Golding, J. & Mason, N. J., 03 Nov 2016, In : Cancer Nanotechnology. 7, 8, 20 p.

Research output: Contribution to journalReview article

Open Access
File
119 Citations (Scopus)
409 Downloads (Pure)

The European Cancer Patient's Bill of Rights, update and implementation 2016

European Cancer Concord (ECC), 01 Dec 2016, In : ESMO Open. 1, 6, e000127.

Research output: Contribution to journalReview article

Open Access
File
20 Citations (Scopus)
130 Downloads (Pure)
2015

BRCA1, a 'complex' protein involved in the maintenance of genomic stability

Savage, K. I. & Harkin, D. P., Feb 2015, In : The FEBS Journal. 282, 4, p. 630-646 17 p.

Research output: Contribution to journalReview article

55 Citations (Scopus)
Open Access
File
7 Citations (Scopus)
399 Downloads (Pure)

The utility of animal models in developing immunosuppressive agents

McDaid, J., Scott, C. J., Kissenpfennig, A., Chen, H. & Martins, P. N., 15 Jul 2015, In : European Journal of Pharmacology. 759, p. 295-302 8 p.

Research output: Contribution to journalReview article

File
6 Citations (Scopus)
737 Downloads (Pure)
2014

Motion Management for Radical Radiotherapy in Non-small Cell Lung Cancer

Cole, A. J., Hanna, G. G., Jain, S. & O'Sullivan, J., Feb 2014, In : Clinical oncology (Royal College of Radiologists (Great Britain)). 26, 2, p. 67-80 14 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)
2012
23 Citations (Scopus)
2005

Molecular mechanisms of drug resistance

Longley, D. B. & Johnston, P. G., 2005, In : Journal of Pathology. 205, 2, p. 275-292 18 p.

Research output: Contribution to journalReview article

854 Citations (Scopus)