Research output per year
Research output per year
Research output
- 1 - 50 out of 1,468 results
Search results
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2024
Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care
Loewenthal, L., Busby, J., McDowell, R., Brown, T., Burhan, H., Chaudhuri, R., Dennison, P., Dodd, J. W., Doe, S., Faruqi, S., Gore, R., Idris, E., Jackson, D. J., Patel, M., Pantin, T., Pavord, I., Pfeffer, P. E., Price, D. B., Rupani, H. & Siddiqui, S. & 2 others, , May 2024, In: Thorax. 79, 5, p. 403-411 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)165 Downloads (Pure) -
Randomised, phase 1/2a trial of ION-827359, an antisense oligonucleotide inhibitor of ENaC
Sutharsan, S., Fischer, R., Gleiber, W., Horsley, A., Crosby, J., Guo, S., Xia, S., Yu, R., Newman, K. B. & Elborn, J. S., 16 Sept 2024, (Early online date) In: ERJ Open Research. 10, 4, 12 p., 00986-2023.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Randomised controlled trial for the titration of oral corticosteroids using markers of inflammation in severe asthma
Ramsahai, J. M., Simpson, J. L., Cook, A., Gibson, P. G., McDonald, V., Grainge, C., Heaney, L. G. & Wark, P. A. B., 22 Mar 2023, (Early online date) In: Thorax.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2022
Fifteen-minute guide to managing oligoarticular juvenile idiopathic arthritis
McKenna, D., McLaughlin, D., Campbell, C., Mulholland, M., Thompson, A., Loughran, C., Jackson, P. & Rooney, M., Jun 2022, In: Archives of Disease in Childhood: Education and Practice Edition. 107, 3, p. 175-181 7 p.Research output: Contribution to journal › Article › peer-review
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2021
Genomic analyses of Bacteroides fragilis: divisions one and two represent two distinct species
Stewart, L., Patrick, S., Blakely, G., Hoyles, L. & English, J., 07 May 2021.Research output: Contribution to conference › Poster
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Secreted Extracellular Cyclophilin A is a Novel Mediator of Ventilator Induced Lung Injury
Koh, M. W., Baldi, R. F., Soni, S., Handslip, R., Tan, Y. Y., O'Dea, K. P., Malesevic, M., McAuley, D. F., O'Kane, C. M., Patel, B. V., Takata, M. & Wilson, M. R., 13 Apr 2021, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)84 Downloads (Pure) -
2020
A systematic review and meta-analysis of digital health technologies effects on psychotic symptoms in adults with psychosis
Clarke, S., Hanna, D., Mulholland, C., Shannon, C. & Urquhart, C., Sept 2020, In: Psychosis. 11, 4, p. 362-373Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model
Stadelmann, V. A., Thompson, K., Zeiter, S., Camenisch, K., Styger, U., Patrick, S., McDowell, A., Nehrbass, D., Richards, R. G. & Moriarty, T. F., 01 Dec 2020, (Early online date) In: Nature Scientific Reports. 10, 20901.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)105 Downloads (Pure) -
2019
The Effect of Aclidinium on Symptoms Including Cough in COPD: A Phase IV, DoubleBlind, Placebo-Controlled, Parallel-Group Study
Smith, J. A., McGarvey, L., Morice, A. H., Birring, S. S., Wedzicha, J. A., Notari, M., Zapata, A., Segarra, R., Seoane, B. & Jarreta, D., 05 Apr 2019, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)97 Downloads (Pure) -
2018
Arts-based interventions for hospitalised patients with cancer: A systematic literature review
Carswell, C., Reid, J., Walsh, I. & Noble, H., 07 Dec 2018, In: British Journal of Health Care Management. 24, 12, p. 611-616Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)108 Downloads (Pure) -
The evolutionary landscape of colorectal tumorigenesis
The S:CORT Consortium, 31 Aug 2018, In: Nature Ecology and Evolution. 2, 10, p. 1661-1672 12 p.Research output: Contribution to journal › Article › peer-review
93 Citations (Scopus) -
2017
Antibody-induced internalization of the human respiratory syncytial virus fusion protein
Leemans, A., De Schryver, M., Van der Gucht, W., Heykers, A., Pintelon, I., Hotard, A. L., Moore, M. L., Melero, J. A., McLellan, J. S., Graham, B., Broadbent, L., Power, U. F., Caljon, G., Cos, P., Maes, L. & Delputte, P., 03 May 2017, (Early online date) In: Journal of Virology.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)338 Downloads (Pure) -
Bacterial proteases and haemostasis dysregulation in the CF lung
Reihill, J. A., Moreland, M., Jarvis, G. E., McDowell, A., Einarsson, G. G., Elborn, J. S. & Martin, S. L., Jan 2017, In: Journal of Cystic Fibrosis. 16, 1, p. 49-57 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)269 Downloads (Pure) -
Breaking ground; year 2
Ingram, R. & Barnett-Vanes, A., 01 May 2017, How to complete a PhD in the medical and clinical sciences. Wiley-BlackwellResearch output: Chapter in Book/Report/Conference proceeding › Chapter
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Characterisation of eppin function: expression and activity in the lung
Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S., 13 Jul 2017, In: European Respiratory Journal. 50, 1, 1601937.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)206 Downloads (Pure) -
DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles.
Ali, A. A., McCrudden, C. M., McCaffrey, J., McBride, J. W., Cole, G., Dunne, N. J., Robson, T., Kissenpfennig, A., Donnelly, R. F. & McCarthy, H. O., Apr 2017, In: Nanomedicine: Nanotechnology, Biology and Medicine. 13, 3, p. 921-932 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile115 Citations (Scopus)884 Downloads (Pure) -
High-volume haemofiltration for sepsis in adults
Borthwick, E. M., Hill, C. J., Rabindranath, K. S., Maxwell, A. P., McAuley, D. F. & Blackwood, B., 31 Jan 2017, In: The Cochrane database of systematic reviews. 1, 42 p., CD008075.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)525 Downloads (Pure) -
Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy (Review)
Bell, J. M., Shields, M., Watters, J., Hamilton, A., Beringer, T., Elliott, M., Quinlivan, R., Tirupathi, S. & Blackwood, B., 24 Jan 2017, In: Cochrane database of systematic reviews (Online). 1, CD010899.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)522 Downloads (Pure) -
Long-term general and cardiovascular safety of tiotropium/olodaterol in patients with moderate to very severe chronic obstructive pulmonary disease
Buhl, R., Magder, S., Bothner, U., Tetzlaff, K., Voß, F., Loaiza, L., Vogelmeier, C. F. & McGarvey, L., Jan 2017, In: Respiratory Medicine. 122, p. 58-66 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)359 Downloads (Pure) -
Matrix metalloproteinase-8 activity in gingival crevicular fluid: development of a novel assay.
McCrudden, M. T. C., Irwin, C. R., El Karim, I., Linden, G. J. & Lundy, F. T., Jun 2017, In: Journal of periodontal research. 52, 3, p. 556-561 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)591 Downloads (Pure) -
Procedural and short-term safety of bronchial thermoplasty in clinical practice evidence from a national registry and Hospital Episode Statistics
Burn, J., Sims, A. J., Keltie, K., Patrick, H., Welham, S. A., Heaney, L. G. & Niven, R. M., 14 Feb 2017, (Early online date) In: Journal of Asthma. 54, 8, p. 872-879Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.
Omar, S., Clarke, R., Abdullah, H., Brady, C., Corry, J., Winter, H., Touzelet, O., Power, U. F., Lundy, F., McGarvey, L. P. A. & Cosby, S. L., 10 Feb 2017, In: PLoS ONE. 12, 2, 21 p., e0171681.Research output: Contribution to journal › Article › peer-review
Open AccessFile78 Citations (Scopus)307 Downloads (Pure) -
The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia
Mohamed, Y. F., Hamad, M., Ortega, X. P. & Valvano, M. A., Apr 2017, In: Molecular Microbiology. 104, 1, p. 144-162Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)236 Downloads (Pure) -
2016
A Burkholderia type VI effector deamidates Rho GTPases to activate the pyrin inflammasome
Aubert, D. F., Xu, H., Yang, J., Shi, X., Gao, W., Li, L., Bisaro, F., Chen, S., Valvano, M. A. & Shao, F., 11 May 2016, In: Cell Host & Microbe. 19, 5, p. 664-674 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile137 Citations (Scopus)374 Downloads (Pure) -
A comparison of different pre-lysis methods and extraction kits for recovery of Stretococcus agalacticae (Lancefield group B Streptococcus) DNA from whole blood
Burke, R. M., McKenna, J. P., Cox, C., Coyle, P. V., Shields, M. D. & Fairley, D. J., Oct 2016, In: Journal of Microbiological Methods. 129, p. 103-108 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)1771 Downloads (Pure) -
Acute Respiratory Distress Syndrome
Mac Sweeney, R. & McAuley, D. F., 28 Apr 2016, (Early online date) In: Lancet. 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile357 Citations (Scopus)1755 Downloads (Pure) -
Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review
Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A. & Brazzelli, M., Apr 2016, In: Health Technology Assessment. 20, 25, p. 1-118 118 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Antimicrobial activity of a novel liposomal azithromycin formulation against clinical CF respiratory isolates
Bashi, Y. D., Payne, J., McGrath, S. J., Elborn, J. S., Tunney, M. M. & Kett, V. L., Jun 2016, In: Journal of Cystic Fibrosis. 15, S1, p. S49 1 p., ePs06.6.Research output: Contribution to journal › Meeting abstract › peer-review
Open AccessFile235 Downloads (Pure) -
A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients
Flume, P. A., VanDevanter, D. R., Morgan, E. E., Dudley, M. N., Loutit, J. S., Bell, S. C., Kerem, E., Fischer, R., Smyth, A. R., Aaron, S. D., Conrad, D., Geller, D. E. & Elborn, J. S., 28 Jul 2016, In: Journal of Cystic Fibrosis. 15, 4, p. 495-502 8 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Citations (Scopus) -
ArnT proteins that catalyse the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases
Tavares-Carreón, F., Mohamed, Y. F., Andrade, A. & Valvano, M. A., 2016, In: Glycobiology. 26, 3, p. 286-300 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)212 Downloads (Pure) -
A Secretory Leukocyte Protease Inhibitor Variant with Improved Activity against Lung Infection
Camper, N., Glasgow, A. M. A., Osbourn, M., Quinn, D. J., Small, D. M., McLean, D. T., Lundy, F. T., Elborn, J. S., McNally, P., Ingram, R. J., Weldon, S. & Taggart, C. C., May 2016, In: Mucosal immunology. 9, 3, p. 669-676Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)368 Downloads (Pure) -
Asthma control and exacerbations: two different sides of the same coin. two different sides of the same coin
Heaney, L. G. & Brisk, R., Jan 2016, In: Current Opinon in Pulmonary Medicine. 22, 1, p. 32-37 6 p.Research output: Contribution to journal › Review article › peer-review
15 Citations (Scopus) -
Behavior change theory, content and delivery of interventions to enhance adherence in chronic respiratory disease: A systematic review
McCullough, A. R., Ryan, C., Macindoe, C., Yii, N., Bradley, J. M., O'Neill, B., Elborn, J. S. & Hughes, C. M., Jul 2016, In: Respiratory Medicine. 116, p. 78-84 7 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells
El Karim, I. A., McCrudden, M. T. C., McGahon, M. K., Curtis, T. M., Jeanneau, C., Giraud, T., Irwin, C. R., Linden, G. J., Lundy, F. T. & About, I., Apr 2016, In: Journal of Endodontics. 42, 4, p. 589-595 7 p.Research output: Contribution to journal › Article › peer-review
File31 Citations (Scopus)698 Downloads (Pure) -
CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor
Ascough, S., Ingram, R. J., Chu, K. K. Y., Musson, J. A., Moore, S. J., Gallagher, T., Baillie, L., Williamson, E. D., Robinson, J. H., Maillere, B., Boyton, R. J. & Altmann, D. M., Jan 2016, In: Frontiers in Microbiology. 6, 12 p., 1506.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)278 Downloads (Pure) -
Chronic inflammation in CF airways - a persistent issue for A20
McCollum, K., El Banna, A., Ennis, M. & Schock, B., 19 Aug 2016, In: Journal of Genetic Syndromes & Gene Therapy .Research output: Contribution to journal › Article › peer-review
Open AccessFile440 Downloads (Pure) -
Cigarettes, e-cigarettes and Pseudomonas aeruginosa: Interactions in the CF lung?
McGown, K.-A., Bengoechea, J., Dumigan, A., Elborn, J. S., Tunney, M. M. & Gilpin, D., Jun 2016, In: Journal of Cystic Fibrosis. 15, Supplement 1, p. S65 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation
Moazed, F., Burnham, E. L., Vandivier, R. W., O'Kane, C. M., Shyamsundar, M., Hamid, U., Abbott, J., Thickett, D. R., Matthay, M. A., McAuley, D. F. & Calfee, C. S., 02 Feb 2016, (Early online date) In: Thorax. 71, p. 1130 8 p.Research output: Contribution to journal › Article › peer-review
58 Citations (Scopus) -
Closed circuit rebreathing to achieve inert gas wash-in for multiple breath wash-out
Horsley, A. R., O'Neill, K., Downey, D. G., Elborn, J. S., Bell, N. J., Smith, J. & Owers-Bradley, J., 09 Feb 2016, In: ERJ Open Research. 2, 1, 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)338 Downloads (Pure) -
Community dynamics and the lower airway microbiota in stable chronic obstructive pulmonary disease, smokers and healthy non-smokers
Einarsson, G. G., Comer, D. M., McIlreavey, L., Parkhill, J., Ennis, M., Tunney, M. M. & Elborn, J. S., 12 Aug 2016, In: Thorax. 71, p. 795-803Research output: Contribution to journal › Article › peer-review
160 Citations (Scopus) -
Comorbidity in severe asthma requiring systemic corticosteroid therapy: Cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry
Sweeney, J., Patterson, C. C., Menzies-Gow, A., Niven, R. M., Mansur, A. H., Bucknall, C., Chaudhuri, R., Price, D., Brightling, C. E. & Heaney, L. G., Mar 2016, In: Thorax. 71, 4, p. 339-346 8 p.Research output: Contribution to journal › Article › peer-review
Open Access275 Citations (Scopus) -
Connectivity Mapping (ssCMap) To Predict A20 Inducing Drugs: Anti-inflammatory Action In Cystic Fibrosis
Malcomson, B., Wilson, H., Thillaiyampalan, G., Barsden, R., Donegan, S., El Banna, A., Elborn, J., Ennis, M., Kelly, C., Zhang, S.-D. & Schock, B., 28 Jun 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3725–E3734 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus)328 Downloads (Pure) -
Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation
De Majumdar, S., Yu, J., Fookes, M., McAteer, S. P., Llobet, E., Spence, S. F. S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., 11 May 2016, In: PLoS Pathogens. 12, 5, p. e1005649Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)275 Downloads (Pure) -
Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma
BTS Severe Asthma Network, 01 Sept 2016, In: Respiratory Medicine. 118, p. 46-52Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Efficacy and Long-Term Outcomes of Palivizumab Prophylaxis to Prevent Respiratory Syncytial Virus Infection in Infants with Cystic Fibrosis in Northern Ireland
Groves, H. E., Jenkins, L., Macfarlane, M., Reid, A., Lynn, F. & Shields, M. D., 25 Jan 2016, (Early online date) In: Pediatric Pulmonology. 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)832 Downloads (Pure) -
Efficacy and safety of lumacaftor/ivacaftor combination therapy in patients with cystic fibrosis homozygous for Phe508del CFTR by pulmonary function subgroup
VX-809 TRAFFIC Study group & TRANSPORT Study Group, Aug 2016, In: The Lancet Respiratory Medicine. 4, 8, p. 617-626Research output: Contribution to journal › Article › peer-review
Open AccessFile133 Citations (Scopus)486 Downloads (Pure) -
EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression.
Currier, M. G., Lee, S., Stobart, C. C., Hotard, A. L., Villenave, R., Meng, J., Pretto, C., Shields, M. D., Nguyen, M. T., Todd, S. O., Chi, M. H., Hammonds, J., Krumm, S. A., Spearman, P., Plemper, R. K., Sakamoto, K., Peebles, R. S., Power, U. F. & Moore, M. L., 06 May 2016, In: PLoS Pathogens. 12, 5, 1005622.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)275 Downloads (Pure) -
Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness
Scott, J., Harris, G. J., Pinder, E. M., Macfarlane, J. G., Hellyer, T. P., Rostron, A. J., Conway Morris, A., Thickett, D. R., Perkins, G. D., McAuley, D. F., Widdrington, J. D., Wiscombe, S., Baudouin, S. V., Roy, A. I., Linnett, V. C., Wright, S. E., Ruchaud-Sparagano, M. H. & Simpson, A. J., 01 Feb 2016, In: The Journal of allergy and clinical immunology. 137, 2, p. 535-544 10 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Exhaled breath temperature measurement and asthma control in children prescribed inhaled corticosteroids: A cross sectional study
Hamill, L., Ferris, K., Kampande, K., McConaghy, L., Douglas, I., McGovern, V. & Shields, M. D., Jan 2016, In: Pediatric Pulmonology. 51, 1, p. 13-21 9 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: a qualitative-evidence synthesis
Jordan, J., Noyes, J., Dainty, K., Rose, L. & Blackwood, B., 04 Oct 2016, In: Cochrane database of systematic reviews (Online). 10, 82 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)869 Downloads (Pure)