Centre for Infection and Immunity

Research Output

Research Output per year

1978 2020

• 63593 Citations
• 112 h-Index
• 1208 Article
• 70 Paper
• 53 Chapter
• 45 Meeting abstract
• 114 More
  • 28 Abstract
  • 25 Poster
  • 12 Review article
  • 10 Chapter (peer-reviewed)
  • 8 Book
  • 8 Literature review
  • 7 Other
  • 5 Editorial
  • 4 Letter
  • 2 Conference contribution
  • 2 Web publication/site
  • 1 Other chapter contribution
  • 1 Comment/debate
  • 1 Patent

Research Output per year

Research Output per year

Search results

• 2020

  Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model

  Stadelmann, V. A., Thompson, K., Zeiter, S., Camenisch, K., Styger, U., Patrick, S., McDowell, A., Nehrbass, D., Richards, R. G. & Moriarty, T. F., 01 Dec 2020, In : Nature Scientific Reports. 10, 20901.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • micro-computed tomography
  • bacterial infections
  • screws
  • animal models
  • bones
  27 Downloads (Pure)
• 2019

  A systematic review and meta-analysis of digital health technologies effects on psychotic symptoms in adults with psychosis

  Clarke, S., Hanna, D., Mulholland, C., Shannon, C. & Urquhart, C., 08 Nov 2019, In : Psychosis. 11, 4, p. 362-373

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Remediation
  • Biomedical Technology
  • Psychotic Disorders
  • Meta-Analysis
  • Systematic Reviews
  1 Citation (Scopus)

• The Effect of Aclidinium on Symptoms Including Cough in COPD: A Phase IV, DoubleBlind, Placebo-Controlled, Parallel-Group Study

  Smith, J. A., McGarvey, L., Morice, A. H., Birring, S. S., Wedzicha, J. A., Notari, M., Zapata, A., Segarra, R., Seoane, B. & Jarreta, D., 05 Apr 2019, In : American Journal of Respiratory and Critical Care Medicine.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Citations (Scopus)

  27 Downloads (Pure)
• 2018

  Arts-based interventions for hospitalised patients with cancer: A systematic literature review

  Carswell, C., Reid, J., Walsh, I. & Noble, H., 07 Dec 2018, In : British Journal of Health Care Management. 24, 12, p. 611-616

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Art
  • Systematic Reviews
  • Art Therapy
  • Neoplasms
  • MEDLINE
  2 Citations (Scopus)

  90 Downloads (Pure)

• The evolutionary landscape of colorectal tumorigenesis

  The S:CORT Consortium, 31 Aug 2018, In : Nature Ecology and Evolution. 2, 10, p. 1661-1672 12 p.

  Research output: Contribution to journal › Article › peer-review

  • adenoma
  • carcinogenesis
  • carcinoma
  • fitness
  • tumor
  31 Citations (Scopus)
• 2017

  Antibody-induced internalization of the human respiratory syncytial virus fusion protein

  Leemans, A., De Schryver, M., Van der Gucht, W., Heykers, A., Pintelon, I., Hotard, A. L., Moore, M. L., Melero, J. A., McLellan, J. S., Graham, B., Broadbent, L., Power, U. F., Caljon, G., Cos, P., Maes, L. & Delputte, P., 03 May 2017, In : Journal of Virology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • viral fusion proteins
  • Human orthopneumovirus
  • Respiratory syncytial virus
  • Viral Fusion Proteins
  • Human respiratory syncytial virus
  8 Citations (Scopus)

  273 Downloads (Pure)

• Bacterial proteases and haemostasis dysregulation in the CF lung

  Reihill, J. A., Moreland, M., Jarvis, G. E., McDowell, A., Einarsson, G. G., Elborn, J. S. & Martin, S. L., Jan 2017, In : Journal of Cystic Fibrosis. 16, 1, p. 49-57 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pathogens
  • Platelets
  • Hemostasis
  • Cystic Fibrosis
  • Agglomeration
  1 Citation (Scopus)

  224 Downloads (Pure)

• Characterisation of eppin function: expression and activity in the lung

  Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S., 13 Jul 2017, In : European Respiratory Journal. 50, 1, 1601937.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Myeloid Cells
  • Lung
  • Chemokine CXCL2
  • Serine Proteinase Inhibitors
  • Neutrophil Infiltration
  2 Citations (Scopus)

  156 Downloads (Pure)

• DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles.

  Ali, A. A., McCrudden, C. M., McCaffrey, J., McBride, J. W., Cole, G., Dunne, N. J., Robson, T., Kissenpfennig, A., Donnelly, R. F. & McCarthy, H. O., Apr 2017, In : Nanomedicine: Nanotechnology, Biology and Medicine. 13, 3, p. 921-932 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • DNA
  • Nanoparticles
  • Uterine Cervical Neoplasms
  • Genes
  • Vaccination
  44 Citations (Scopus)

  315 Downloads (Pure)

• High-volume haemofiltration for sepsis in adults

  Borthwick, E. M., Hill, C. J., Rabindranath, K. S., Maxwell, A. P., McAuley, D. F. & Blackwood, B., 31 Jan 2017, In : The Cochrane database of systematic reviews. 1, 42 p., CD008075.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hemofiltration
  • Sepsis
  • Septic Shock
  • Intensive Care Units
  • Critical Illness
  24 Citations (Scopus)

  405 Downloads (Pure)

• Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy (Review)

  Bell, J. M., Shields, M., Watters, J., Hamilton, A., Beringer, T., Elliott, M., Quinlivan, R., Tirupathi, S. & Blackwood, B., 24 Jan 2017, In : Cochrane database of systematic reviews (Online). 1, CD010899.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Osteoporotic Fractures
  • Duchenne Muscular Dystrophy
  • Osteoporosis
  • Steroids
  • Vibration
  4 Citations (Scopus)

  321 Downloads (Pure)

• Long-term general and cardiovascular safety of tiotropium/olodaterol in patients with moderate to very severe chronic obstructive pulmonary disease

  Buhl, R., Magder, S., Bothner, U., Tetzlaff, K., Voß, F., Loaiza, L., Vogelmeier, C. F. & McGarvey, L., Jan 2017, In : Respiratory Medicine. 122, p. 58-66 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • tiotropium-olodaterol
  • Chronic Obstructive Pulmonary Disease
  • Safety
  • Morbidity
  • olodaterol
  24 Citations (Scopus)

  242 Downloads (Pure)

• Matrix metalloproteinase-8 activity in gingival crevicular fluid: development of a novel assay.

  McCrudden, M. T. C., Irwin, C. R., El Karim, I., Linden, G. J. & Lundy, F. T., Jun 2017, In : Journal of periodontal research. 52, 3, p. 556-561 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Matrix Metalloproteinase 8
  • Gingival Crevicular Fluid
  • Periodontal Diseases
  • Matrix Metalloproteinases
  • Fluorescent Dyes
  3 Citations (Scopus)

  306 Downloads (Pure)

• Procedural and short-term safety of bronchial thermoplasty in clinical practice evidence from a national registry and Hospital Episode Statistics

  Burn, J., Sims, A. J., Keltie, K., Patrick, H., Welham, S. A., Heaney, L. G. & Niven, R. M., 14 Feb 2017, In : Journal of Asthma. 54, 8, p. 872-879

  Research output: Contribution to journal › Article › peer-review

  • Bronchial Thermoplasty
  • Registries
  • Statistics
  • Safety
  • Asthma
  9 Citations (Scopus)

• Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.

  Omar, S., Clarke, R., Abdullah, H., Brady, C., Corry, J., Winter, H., Touzelet, O., Power, U. F., Lundy, F., McGarvey, L. P. A. & Cosby, S. L., 10 Feb 2017, In : PLoS ONE. 12, 2, 21 p., e0171681.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • TRPV1 receptor
  • Viruses
  • Respiratory Tract Infections
  • Virus Diseases
  • Up-Regulation
  25 Citations (Scopus)

  230 Downloads (Pure)

• The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia

  Mohamed, Y. F., Hamad, M., Ortega, X. P. & Valvano, M. A., Apr 2017, In : Molecular Microbiology. 104, 1, p. 144-162

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Burkholderia cenocepacia
  • Acyltransferases
  • Rubiaceae
  • Acylation
  • Lipid A
  3 Citations (Scopus)

  114 Downloads (Pure)

• Tropical ulcer plant treatments used by Papua New Guinea's Apsokok nomads

  Prescott, T. A. K., Homot, P., Lundy, F. T., Patrick, S., Cámara-Leret, R. & Kiapranis, R., 03 May 2017, In : Journal of Ethnopharmacology. 205, p. 240-245 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Papua New Guinea
  • Ulcer
  • Matrix Metalloproteinases
  • Inhibition (Psychology)
  • Staphylococcus aureus
  5 Citations (Scopus)

  261 Downloads (Pure)
• 2016

  A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome

  Aubert, D. F., Xu, H., Yang, J., Shi, X., Gao, W., Li, L., Bisaro, F., Chen, S., Valvano, M. A. & Shao, F., 11 May 2016, In : Cell host & microbe. 19, 5, p. 664-674 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pyrin
  • Burkholderia cenocepacia
  • Burkholderia
  • rho GTP-Binding Proteins
  • Inflammasomes
  73 Citations (Scopus)

  237 Downloads (Pure)

• A comparison of different pre-lysis methods and extraction kits for recovery of Stretococcus agalacticae (Lancefield group B Streptococcus) DNA from whole blood

  Burke, R. M., McKenna, J. P., Cox, C., Coyle, P. V., Shields, M. D. & Fairley, D. J., Oct 2016, In : Journal of Microbiological Methods. 129, p. 103-108 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Streptococcus agalactiae
  • Bacterial DNA
  • DNA
  • Nucleic Acids
  • lysyl endopeptidase
  6 Citations (Scopus)

  866 Downloads (Pure)

• Acute Respiratory Distress Syndrome

  Mac Sweeney, R. & McAuley, D. F., 28 Apr 2016, In : Lancet. 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adult Respiratory Distress Syndrome
  • Hypoxia
  • Neuromuscular Blockade
  • Prone Position
  • Extracorporeal Membrane Oxygenation
  149 Citations (Scopus)

  1365 Downloads (Pure)

• Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

  Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A. & Brazzelli, M., Apr 2016, In : Health Technology Assessment. 20, 25, p. 1-118 118 p.

  Research output: Contribution to journal › Article › peer-review

  • Dexmedetomidine
  • Intensive Care Units
  • Systematic Reviews
  • Lorazepam
  • Hypnotics and Sedatives
  30 Citations (Scopus)

• Altered lung microbiota profiles are associated with disease severity, exacerbation frequency and neutrophilic inflammation in bronchiectasis: B16. CYSTIC FIBROSIS (CF) AND NON-CF BRONCHIECTASIS

  Dicker, A. J., Fong, C., Crichton, M., Cassidy, A., Suarez-Cuartin, G., Sibila, O., Einarsson, G. G., Ibrahim, W., Elborn, J. S. & Palmer, C. NA., 2016, p. A2879-A2879.

  Research output: Contribution to conference › Abstract › peer-review

  • Bronchiectasis
  • Microbiota
  • Cystic Fibrosis
  • Disease Progression
  • Inflammation

• Antimicrobial activity of a novel liposomal azithromycin formulation against clinical CF respiratory isolates

  Bashi, Y. D., Payne, J., McGrath, S. J., Elborn, J. S., Tunney, M. M. & Kett, V. L., Jun 2016, In : Journal of Cystic Fibrosis. 15, S1, p. S49 1 p., ePs06.6.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  File
  173 Downloads (Pure)

• ArnT proteins that catalyse the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases

  Tavares-Carreón, F., Mohamed, Y. F., Andrade, A. & Valvano, M. A., 2016, In : Glycobiology. 26, 3, p. 286-300 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycosylation
  • dolichyl-diphosphooligosaccharide - protein glycotransferase
  • Lipid A
  • Lipopolysaccharides
  • Burkholderia cenocepacia
  7 Citations (Scopus)

  123 Downloads (Pure)

• A Secretory Leukocyte Protease Inhibitor Variant with Improved Activity against Lung Infection

  Camper, N., Glasgow, A. M. A., Osbourn, M., Quinn, D. J., Small, D. M., McLean, D. T., Lundy, F. T., Elborn, J. S., McNally, P., Ingram, R. J., Weldon, S. & Taggart, C. C., May 2016, In : Mucosal immunology. 9, 3, p. 669-676

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Secretory Leukocyte Peptidase Inhibitor
  • Lung
  • Infection
  • Leukocyte Elastase
  • Cystic Fibrosis
  14 Citations (Scopus)

  314 Downloads (Pure)

• Asthma control and exacerbations: two different sides of the same coin. two different sides of the same coin

  Heaney, L. G. & Brisk, R., Jan 2016, In : Current Opinon in Pulmonary Medicine. 22, 1, p. 32-37 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Numismatics
  • Asthma
  • Biomarkers
  • Adrenal Cortex Hormones
  • Inflammation
  13 Citations (Scopus)

• Behavior change theory, content and delivery of interventions to enhance adherence in chronic respiratory disease: A systematic review

  McCullough, A. R., Ryan, C., Macindoe, C., Yii, N., Bradley, J. M., O'Neill, B., Elborn, J. S. & Hughes, C. M., Jul 2016, In : Respiratory Medicine. 116, p. 78-84 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Self-Management
  • Systematic Reviews
  • Chronic Disease
  • Treatment Adherence and Compliance
  • Pharmacists
  17 Citations (Scopus)

• Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells

  El Karim, I. A., McCrudden, M. T. C., McGahon, M. K., Curtis, T. M., Jeanneau, C., Giraud, T., Irwin, C. R., Linden, G. J., Lundy, F. T. & About, I., Apr 2016, In : Journal of Endodontics. 42, 4, p. 589-595 7 p.

  Research output: Contribution to journal › Article › peer-review

  File

  • Odontoblasts
  • Tumor Necrosis Factor-alpha
  • Transient Receptor Potential Channels
  • TRPA1 Cation Channel
  • beta-glycerophosphoric acid
  11 Citations (Scopus)

  399 Downloads (Pure)

• Breaking ground; year 2

  Ingram, R. & Barnett-Vanes, A., 2016, (Accepted) How to complete a PhD in the medical and clinical sciences. Wiley-Blackwell

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor

  Ascough, S., Ingram, R. J., Chu, K. K. Y., Musson, J. A., Moore, S. J., Gallagher, T., Baillie, L., Williamson, E. D., Robinson, J. H., Maillere, B., Boyton, R. J. & Altmann, D. M., Jan 2016, In : Frontiers in Microbiology. 6, 12 p., 1506.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bacillus anthracis
  • Epitopes
  • Immunodominant Epitopes
  • T-Lymphocytes
  • HLA-DR Antigens
  8 Citations (Scopus)

  242 Downloads (Pure)

• Chronic inflammation in CF airways - a persistent issue for A20

  McCollum, K., El Banna, A., Ennis, M. & Schock, B., 19 Aug 2016, In : Journal of Genetic Syndromes & Gene Therapy .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cystic Fibrosis
  • Inflammation
  • gibberellic acid
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • Messenger RNA
  353 Downloads (Pure)

• Cigarettes, e-cigarettes and Pseudomonas aeruginosa: Interactions in the CF lung?

  McGown, K-A., Bengoechea, J., Dumigan, A., Elborn, J. S., Tunney, M. M. & Gilpin, D., Jun 2016, In : Journal of Cystic Fibrosis. 15, Supplement 1, p. S65 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation

  Moazed, F., Burnham, E. L., Vandivier, R. W., O'Kane, C. M., Shyamsundar, M., Hamid, U., Abbott, J., Thickett, D. R., Matthay, M. A., McAuley, D. F. & Calfee, C. S., 02 Feb 2016, In : Thorax. 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco Products
  • Inhalation
  • Bronchoalveolar Lavage
  • Lipopolysaccharides
  • Smokers
  28 Citations (Scopus)

• Closed circuit rebreathing to achieve inert gas wash-in for multiple breath wash-out

  Horsley, A. R., O'Neill, K., Downey, D. G., Elborn, J. S., Bell, N. J., Smith, J. & Owers-Bradley, J., 09 Feb 2016, In : ERJ Open Research. 2, 1, 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Noble Gases
  • Cystic Fibrosis
  • Lung
  5 Citations (Scopus)

  271 Downloads (Pure)

• Community dynamics and the lower airway microbiota in stable chronic obstructive pulmonary disease, smokers and healthy non-smokers

  Einarsson, G. G., Comer, D. M., McIlreavey, L., Parkhill, J., Ennis, M., Tunney, M. M. & Elborn, J. S., 12 Aug 2016, In : Thorax. 71, p. 795-803

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Non-Smokers
  • Chronic Obstructive Pulmonary Disease
  • Smokers
  • Prevotella
  72 Citations (Scopus)

• Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry

  Sweeney, J., Patterson, C. C., Menzies-Gow, A., Niven, R. M., Mansur, A. H., Bucknall, C., Chaudhuri, R., Price, D., Brightling, C. E. & Heaney, L. G., Mar 2016, In : Thorax. 71, 4, p. 339-346 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adrenal Cortex Hormones
  • Registries
  • Comorbidity
  • Patient Care
  • Asthma
  123 Citations (Scopus)

• Connectivity Mapping (ssCMap) To Predict A20 Inducing Drugs: Anti-inflammatory Action In Cystic Fibrosis

  Malcomson, B., Wilson, H., Thillaiyampalan, G., Barsden, R., Donegan, S., El Banna, A., Elborn, J., Ennis, M., Kelly, C., Zhang, S-D. & Schock, B., 28 Jun 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3725–E3734 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cystic Fibrosis
  • ikarugamycin
  • NF-kappa B
  • Epithelial Cells
  • Pharmaceutical Preparations
  25 Citations (Scopus)

  213 Downloads (Pure)

• Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

  De Majumdar, S., Yu, J., Fookes, M., McAteer, S. P., Llobet, E., Spence, S. F. S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., 11 May 2016, In : PLoS Pathogens. 12, 5, p. e1005649

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Regulon
  • Klebsiella pneumoniae
  201 Downloads (Pure)

• Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2): Study protocol for a randomised controlled trial

  Hellyer, T. P., Anderson, N. H., Parker, J., Dark, P., van den Broeck, T., Singh, S., McMullan, R., Agus, A., Emerson, L. M., Blackwood, B., Gossain, S., Walsh, T., Perkins, G., Conway Morris, A., McAuley, D. F. & Simpson, A. J., 16 Jul 2016, In : Trials. 17, 1, 8 p., 318.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mechanical Ventilators
  • Pneumonia
  • Randomized Controlled Trials
  • Biomarkers
  • Anti-Bacterial Agents
  8 Citations (Scopus)

  167 Downloads (Pure)

• Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma

  BTS Severe Asthma Network, 01 Sep 2016, In : Respiratory Medicine. 118, p. 46-52

  Research output: Contribution to journal › Article › peer-review

  • Age of Onset
  • Asthma
  • Eosinophils
  • Elderly
  • Patient Acceptance of Health Care
  4 Citations (Scopus)

• Efficacy and Long-Term Outcomes of Palivizumab Prophylaxis to Prevent Respiratory Syncytial Virus Infection in Infants with Cystic Fibrosis in Northern Ireland

  Groves, H. E., Jenkins, L., Macfarlane, M., Reid, A., Lynn, F. & Shields, M. D., 25 Jan 2016, In : Pediatric Pulmonology. 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Palivizumab
  • Northern Ireland
  • Respiratory Syncytial Virus Infections
  • Cystic Fibrosis
  • Hospitalization
  14 Citations (Scopus)

  612 Downloads (Pure)

• Efficacy and safety of lumacaftor/ivacaftor combination therapy in patients with cystic fibrosis homozygous for Phe508del CFTR by pulmonary function subgroup

  VX-809 TRAFFIC Study group & TRANSPORT Study Group, Aug 2016, In : The Lancet Respiratory Medicine. 4, 8, p. 617-626

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • ivacaftor drug combination lumacaftor
  • ivacaftor
  • lumacaftor
  • Cystic Fibrosis
  • Forced Expiratory Volume
  72 Citations (Scopus)

  407 Downloads (Pure)

• EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression.

  Currier, M. G., Lee, S., Stobart, C. C., Hotard, A. L., Villenave, R., Meng, J., Pretto, C., Shields, M. D., Nguyen, M. T., Todd, S. O., Chi, M. H., Hammonds, J., Krumm, S. A., Spearman, P., Plemper, R. K., Sakamoto, K., Peebles, R. S., Power, U. F. & Moore, M. L., 06 May 2016, In : PLoS Pathogens. 12, 5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Respiratory Syncytial Viruses
  • Mucins
  • ErbB Receptors
  • varespladib methyl
  • Infection
  23 Citations (Scopus)

  229 Downloads (Pure)

• Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β₂-agonists, corticosteroids, and critical illness

  Scott, J., Harris, G. J., Pinder, E. M., Macfarlane, J. G., Hellyer, T. P., Rostron, A. J., Conway Morris, A., Thickett, D. R., Perkins, G. D., McAuley, D. F., Widdrington, J. D., Wiscombe, S., Baudouin, S. V., Roy, A. I., Linnett, V. C., Wright, S. E., Ruchaud-Sparagano, M. H. & Simpson, A. J., 01 Feb 2016, In : The Journal of allergy and clinical immunology. 137, 2, p. 535-544 10 p.

  Research output: Contribution to journal › Article › peer-review

  • erythromycin propionate-N-acetylcysteinate
  • Neutrophil Activation
  • Cyclic AMP
  • Critical Illness
  • Adrenal Cortex Hormones
  16 Citations (Scopus)

• Exhaled breath temperature measurement and asthma control in children prescribed inhaled corticosteroids: A cross sectional study

  Hamill, L., Ferris, K., Kampande, K., McConaghy, L., Douglas, I., McGovern, V. & Shields, M. D., Jan 2016, In : Pediatric Pulmonology. 51, 1, p. 13-21 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenal Cortex Hormones
  • Asthma
  • Temperature
  • Cross-Sectional Studies
  • Child
  11 Citations (Scopus)

• Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: a qualitative-evidence synthesis

  Jordan, J., Noyes, J., Dainty, K., Rose, L. & Blackwood, B., 04 Oct 2016, In : Cochrane database of systematic reviews (Online). 10, 82 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Weaning
  • Artificial Respiration
  • Critical Illness
  • Child
  • Intensive Care Units
  5 Citations (Scopus)

  518 Downloads (Pure)

• Fetal umbilical artery Doppler pulsatility index and childhood neurocognitive outcome at 12 years

  Mone, F., McConnell, B., Thompson, A., Segurado, R., Hepper, P., Stewart, M. C., Dornan, J. C., Ong, S., McAuliffe, F. M. & Shields, M. D., 15 Jun 2016, In : BMJ Open. 6, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Umbilical Arteries
  • Child
  • Pregnancy
  • Fetal Growth Retardation
  • Electronic Data Processing
  3 Citations (Scopus)

  733 Downloads (Pure)

• Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

  Detalle, L., Stohr, T., Palomo, C., Piedra, P. A., Gilbert, B. E., Mas, V., Millar, A., Power, U. F., Stortelers, C., Allosery, K., Melero, J. A. & Depla, E., Jan 2016, In : Antimicrobial Agents and Chemotherapy. 60, 1, p. 6-13 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Palivizumab
  • Virus Diseases
  • Antiviral Agents
  94 Citations (Scopus)

  400 Downloads (Pure)

• Genomic meningococcal load in the nasopharynx of children with meningococcal disease

  Bourke, T. W., McKenna, J. P., Coyle, P. V., Fairley, D. J. & Shields, M. D., May 2016, In : The Pediatric Infectious Disease Journal. 35, 5, p. 577-579

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Meningococcal Infections
  • Neisseria meningitidis
  • Bacterial Load
  • Nasopharynx
  • Feasibility Studies
  265 Downloads (Pure)

• Hydrogel Forming Microneedles a Promising Minimally Invasive Tool to Deliver Clinically Relevant Doses of Methotrexate to Treat Paediatric Rheumatoid Arthritis

  Tekko, I., Donnelly, R., McElnay, J., McCarthy, H. & Rooney, M., 2016.

  Research output: Contribution to conference › Poster › peer-review