Research Output 1970 2020

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Meeting abstract
2019

A foundation in acute paediatrics (FAPS) – enhancing perceptions of paediatrics and stimulating speciality recruitment using a simulation recruiter course

Mallett, P., Junk, C., Flannigan, C., Fitzsimons, A., Thompson, A. & Bourke, T., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A253-A254 G626P.

Research output: Contribution to journalMeeting abstract

Altering the balance of Rho GTPase pathways in CLL determines CLL cell fate

Samir, Y., Rees-Unwin, K., Graham, C., Graham, R., Rahi, R., Adams, J. & Burthem, J., 27 Mar 2019, In : British Journal of Haematology. 185, S1, p. 171-172

Research output: Contribution to journalMeeting abstract

An evaluation of the impact of environmental priming on clinical performance in simulated paediatric emergencies – a randomised controlled trial

McNaughten, B., Storey, L., Corkin, D., Cardwell, P., Thompson, A., Bourke, T. & O'Donoghue, D., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A252

Research output: Contribution to journalMeeting abstract

Assessment of novel disinfection technologies, and bacterial contamination in the healthcare setting

Murray, J., Ternan, N., Gill, C., McMullan, G., Farren, D. & Scott, M., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access

Development of a co-designed written resource for carers of patients with heart failure

Cassidy, L., Hill, L. & Fitzsimons, D., 26 May 2019, In : European Journal of Heart Failure. 21, S1, p. p95 1 p.

Research output: Contribution to journalMeeting abstract

Caregivers
Heart Failure
Pamphlets
Northern Ireland
Delivery of Health Care

Development of a theory-based intervention to improve medicines management for people with dementia in primary care

Barry, H. E., Bedford, L., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Feb 2019, In : International Journal of Clinical Pharmacy. 41, 1, p. 290 1 p.

Research output: Contribution to journalMeeting abstract

Evaluation of Novel Serine Protease Inhibitors to Ameliorate Cockroach-Induced Airway Inflammation and Cell Damage

Reihill, J., Yang, Z., Carroll, E., McGarvey, L., Lundy, F., Lockhart, J., Sergeant, G. & Martin, L., 01 Apr 2019, In : The FASEB Journal. 33, Suppl. 1, 127.10.

Research output: Contribution to journalMeeting abstract

Fluorescence Lifetime Imaging of Tetracycline-Stained Retinal Hydroxyapatite: An Early Biomarker for Age-Related Macular Degeneration?

Thompson, R. B., Szmacinski, H., Hegde, K., Puche, A., McGill, T., Neuringer, M. & Lengyel, I., 15 Feb 2019, In : Biophysical Journal. 116, 3, p. 566a 1 p.

Research output: Contribution to journalMeeting abstract

Optical Imaging
Macular Degeneration
Durapatite
Tetracycline
Biomarkers

Furin Inhibition as a Mechanism to Reduce Aberrant ENaC-Mediated Sodium Transport and Rehydrate the Airways in Cystic Fibrosis Lung Disease

Douglas, L., Reihill, J., Ho, M., Axten, J. & Martin, L., 01 Apr 2019, In : The FASEB Journal. 33, Suppl. 1, 802.26.

Research output: Contribution to journalMeeting abstract

Healthy Primary Epithelial Cells Show an Elevated Inflammatory Response to Bacterial Stimulus Compared to COPD Cells

Carson, S., Reihill, J., Lundy, F., McGarvey, L., Crilly, A., Fulton, C., Thornbury, K. & Martin, L., 01 Apr 2019, In : The FASEB Journal. 33, Suppl. 1, 127.7.

Research output: Contribution to journalMeeting abstract

Inaugural national sim-off event: promoting paediatric sim-based education & region wide sim-enthusiasm

Mallett, P., Junk, C., Laird, E., McNaughten, B., Bourke, T. & Thompson, A., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A257 G635(P) .

Research output: Contribution to journalMeeting abstract

Inhibition of ENaC Activity by Novel Peptide Trypsin-Like Inhibitors Derived from Amphibian Skin Secretions

Carroll, E., Douglas, L., Reihill, J., Zhou, M., Chen, T., McGarvey, L., Lundy, F., Hollywood, M., Lockhart, J. & Martin, L., 01 Apr 2019, In : The FASEB Journal. 33, Suppl. 1, 127.9.

Research output: Contribution to journalMeeting abstract

Investigation of a hospital Enterobacter cloacae NDM-1 outbreak using whole genome sequencing

Fairley, D., Protaschik, Y., Finn, R., Turton, J., Doumith, M., Elbaz, W., Hedderwick, S. & Bradley, D., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access

Levels of the novel peptide Intermedin/Adrenomedullin-2 in patients with pulmonary arterial hypertension

Thomas, G., Watson, C., McMechan, S., Smyth, A., Bell, D. & Harbinson, M. T., 01 May 2019, In : Heart (British Cardiac Society). 105, Suppl 4, p. A5-A5 1 p., P2.

Research output: Contribution to journalMeeting abstract

Adrenomedullin
Pulmonary Hypertension
Peptides

Loss of TRIM33 in Multiple Myeloma correlates with increased genomic instability

McAvera, R., Morgan, J., Johnston, C., Mills, K. & Crawford, L., 18 Oct 2019, In : Clinical Lymphoma, Myeloma and Leukemia. 19, Suppl 10, p. e70-e71

Research output: Contribution to journalMeeting abstract

Open Access
Caregivers
Parkinson Disease
Medication Adherence
Therapeutics
Self Care

Non-sporulating variants of C. difficile from animal faecal samples

Vardy, N., McGrath, J., Fairley, D., McMullan, G. & Connor, M., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access

One-hour of Moderate Intensity Exercise does not attenuate DNA Single Strand Breaks and Base Oxidation following High-fat Meal Consumption

McClean, C. M., Brown, M., Murphy, M. H. & Davison, G. W., Jun 2019, In : Medicine & Science in Sports & Exercise. 51, 6, p. 721

Research output: Contribution to journalMeeting abstract

P112 Proton pump inhibitor use is associated with increased pulmonary exacerbations and hospital admissions in adult patients with cystic fibrosis

Ferguson, C., Mckeown, C., Hagan, C., Moore, J. E., McCaughan, J., Kirkwood, Z., Addy, C., Caskey, S. & Downey, D. G., 27 May 2019, In : Journal of Cystic Fibrosis. 18, p. S89

Research output: Contribution to journalMeeting abstract

P206 Does adherence to DNase change following initiation of Orkambi for the treatment of cystic fibrosis?

McKeown, C., O'Neill, B., Addy, C., Caskey, S. & Downey, D. G., 27 May 2019, In : Journal of Cystic Fibrosis. 18, p. S115-S116

Research output: Contribution to journalMeeting abstract

P347 A survey of cardiovascular disease in UK cystic fibrosis centres

Downey, D. G., Bengoechea, J., Curtis, T., Grieve, D. & Harbinson, M., Jun 2019, In : Journal of Cystic Fibrosis. 18, p. S155-S156

Research output: Contribution to journalMeeting abstract

Perceptions and experiences of rare diseases among the GP population in Northern Ireland

McMullan, J., McClenaghan, T., Crowe, A., McKnight, A. & McAneney, H., 06 Jun 2019, In : British Journal of General Practice. 69, Suppl 1, bjgp19X703637.

Research output: Contribution to journalMeeting abstract

Perspectives of community-dwelling people with dementia and their carers about medicines management: a qualitative study

Barry, H. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 03 Apr 2019, In : International Journal of Pharmacy Practice. 27, S2, p. 15-16

Research output: Contribution to journalMeeting abstract

Posters
Rehabilitation
Stroke
Brain
Cardiac Rehabilitation

Poster abstract: Bacterial and fungal co-colonisation leads to poorer clinical outcomes in an adult cystic fibrosis population

Ferguson, C., Moore, J. E., McCaughan, J., Addy, C., Downey, D., Caskey, S. & Hagan, C., Jun 2019, In : Journal of Cystic Fibrosis. 18, Supplement 1, p. S105-S106 2 p., P170.

Research output: Contribution to journalMeeting abstract

Poster abstract: Leveraging structural relationships as a novel mode of viral classification

Magill, D., Skvortsov, T., O’Flaherty, V. & McGrath, J., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access
phylogenetics
protein
gene
holistic approach
bacteriophage

Poster abstract: Understanding the evolution and metabolic capabilities of the Butyrivibrio group

Pidcock, S., Skvortsov, T., Santos, F., Ting, K. S., Creevey, C. & Huws, S., 01 Mar 2019, In : Access Microbiology. 1, 1A, 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
Butyrivibrio
Pseudobutyrivibrio
genome
glycosidases
biohydrogenation

Poster abstract: Use of the Fitbit Charge HR to monitor physical activity, sleep and heart rate during IV therapy for pulmonary exacerbations

Addy, C., Bradley, J. M., Elborn, J. S. & Downey, D. G., Jun 2019, In : Journal of Cystic Fibrosis. 18, Supplement 1, p. S126-S127 2 p., P247 .

Research output: Contribution to journalMeeting abstract

Reducing the trauma of lumbar punctures using simulation

Watterson, C., Mallett, P., Taylor, M. & Bourke, T., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A13 G31(P).

Research output: Contribution to journalMeeting abstract

Scenes, symbols and social roles: OSCE performativity and identities

Gormley, G., Corrigan, M. & Johnston, J., 2019, In : Canadian Medical Education Journal. 10, 2, p. e62 1 p., OB-1-6.

Research output: Contribution to journalMeeting abstract

Testing the feasibility of a community pharmacy-based intervention to improve medicines management for people with dementia in primary care

Barry, H. E., Bedford, L., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 17 Sep 2019, In : European Geriatric Medicine. 10, S1, p. 62-63 2 p.

Research output: Contribution to journalMeeting abstract

The MRC HTMR recruitment working group: Driving recruitment research through collaboration

Harman, N. L., Elliott, D., Gamble, C., Gillies, K., McAneney, H., Realpe, A., Rooshenas, L. & Shorter, G., 06 Oct 2019, In : Trials. 20 , Suppl 1, p. 19-19 P66.

Research output: Contribution to journalMeeting abstract

Open Access

Under-representation in Clinical Trials: Participants with rare diseases, reporting and awareness.

McAneney, H., 06 Oct 2019, In : Trials. 20 , Suppl 1, p. 51-51 P174.

Research output: Contribution to journalMeeting abstract

Open Access

Unpicking the standardisation in OSCEs using Institutional Ethnography

Kearney, G., Johnston, J., Hart, N. & Gormley, G., 13 Apr 2019, In : Canadian Medical Education Journal. 10 , 2 e135-136

Research output: Contribution to journalMeeting abstract

Using a simulated community pharmacy and role-play to teach future pharmacists

Hanna, L-A. & Hall, M., 04 Nov 2019, In : BMJ Simulation and Technology Enhanced Learning. 5, Suppl 2, p. A71-A72

Research output: Contribution to journalMeeting abstract

Pharmacies
pharmacist
role play
Pharmacists
community

WS06-1 Initial results evaluating combinations of the novel CFTR corrector PTI-801, potentiator PTI-808, and amplifier PTI-428 in cystic fibrosis subjects

Downey, D., Flume, P., Jain, M., Fajac, I., Schwarz, C., Pressler, T., Van Koningsbruggen-Rietschel, S., Taylor-Cousar, J., Horsley, A., Sutharsan, S., Miller, J., Poirier, G., Jiang, J., Inoue, T., Wilson, S., Lee, P-S. & Gilmartin, G., Jun 2019, In : Journal of Cystic Fibrosis. 18, Suppl 1, p. S10 1 p.

Research output: Contribution to journalMeeting abstract

2018

A combined first trimester screening strategy for prediction of pre-eclampsia in high-risk women: Results from the PREDICT study.

Eastwood, K-A., Hunter, AJ., Patterson, C., McCance, DR., Young, IS. & Holmes, VA., 17 Apr 2018, In : British Journal of Obstetrics and Gynaecology. 125, S2, p. 93 1 p., PP.021.

Research output: Contribution to journalMeeting abstract

First Pregnancy Trimester
Pre-Eclampsia
12 Citations (Scopus)

A Critical Realist Evaluation of a Music Therapy Intervention in Palliative Care

Reid, J., May 2018, In : Palliative Medicine. 32, Supplement 1, p. 79

Research output: Contribution to journalMeeting abstract

Music Therapy
Palliative Care
Hospices
Northern Ireland
Posters

A cross-sectional analysis of cough swabs from non-expectorating CF patients and healthy control participants

Einarsson, G., Sherrard, L., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Murray, M. A., Lavelle, G. M., McElvaney, N. G., Boucher, R. C., Muhlebach, M. S., Elborn, J. & Tunney, M., 03 Jun 2018, In : Journal of Cystic Fibrosis. 17, Supplement 3, p. S74-S75 1 p., P055.

Research output: Contribution to journalMeeting abstract

Cough
Healthy Volunteers
Cross-Sectional Studies
Adonis
Age Groups

Actup – an interdisciplinary approach to preparing senior paediatric trainees for challenging clinical scenario

McNaughten, B., Sweeney, R., Murphy, P., Storey, L., Bourke, T. & Thompson, A., 2018, In : Archives of Disease in Childhood. 103, G169(P).

Research output: Contribution to journalMeeting abstract

Addressing the psycho-educational needs of caregivers of patients with advanced heart failure: a systematic review

Cassidy, L. L., Hill, L., McGaughey, J., Greene, E. & Fitzsimons, D., 26 May 2018, In : European Journal of Heart Failure. 20, Suppl. S1, p. 153-154 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
Caregivers
Heart Failure
Self Care
Interdisciplinary Communication
Communication
Smooth Muscle Myocytes
Fibroblasts
Lung
Vasodilator Agents
Pulmonary Hypertension

A phase I dose escalation multi-centre study of crizotinib (MET inhibitor) combined with binimetinib (MEK inhibitor) in patients with advanced solid tumours

Wilson, R., Dass, P. H., Van Schaeybroeck, S., Elez, E., Quinton, A., Jones, R., Houlden, J., Collins, L., Roberts, C., Love, S., Lawler, M., Di Nicolantonio, F., Grayson, M., Bardelli, A., Laurent=puig, P., Maughan, T., Tabernero, J., Peeters, M., Middleton, M. & Rolfo, C., Nov 2018, In : European Journal of Cancer. 103, Suppl 1, p. e140-e141

Research output: Contribution to journalMeeting abstract

Mitogen-Activated Protein Kinase Kinases
Neoplasms
Creatinine
Phosphotransferases
Fatigue

A qualitative study of healthcare professionals’ perceptions of barriers and facilitators to successful medicines management for people with dementia in primary care.

Barry, H. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Apr 2018, In : International Journal of Pharmacy Practice. 26, S1, p. 31-32 2 p.

Research output: Contribution to journalMeeting abstract

Open Access

Assessing the state dependent effects of SR-5-6 on Kv7.4 channels expressed in HEK cells.

Rabab, K., Dudem, S., Martin, L., Tikhonova, I., Thornbury, K., Sergeant, G. & Hollywood, M., 01 Nov 2018, In : Irish journal of medical science. 187, Suppl 8, S281.

Research output: Contribution to journalMeeting abstract