Patrick G Johnston Centre for Cancer Research

Search results

• 5-fluorouracil : mechanisms of action (or resistance) in p53-proficient and -deficient colorectal cancer

  Falcone, F. (Author), Longley, D. (Supervisor) & McDade, S. (Supervisor), Jul 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• An innate immune response to DNA damage in prostate cancer

  Davidson, C. (Author), Kennedy, R. (Supervisor), Jain, S. (Supervisor) & McCabe, N. (Supervisor), Dec 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

  File

• A pathways-based approach identifying determinants of drug resistance in oesophageal adenocarcinoma

  McCabe, N. (Author), Kennedy, R. (Supervisor), Turkington, R. (Supervisor) & Stevenson, L. (Supervisor), Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Assessing the impact of non-coding mutations on breast cancer risk predisposition genes

  Ali, R. (Author), Savage, K. (Supervisor) & McIntosh, S. (Supervisor), Dec 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• A systems biology approach to dissect the hazardous effects of spaceflight and investigate induced torpor as a therapeutic countermeasure.

  Cahill, T. (Author), Overton, I. (Supervisor) & Hardiman, G. (Supervisor), Jul 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

  File

• Augmenting radiation sensitivity of HPV-negative head and neck cancer through mannose intervention

  Wang, T. (Author), Coulter, J. (Supervisor) & Butterworth, K. (Supervisor), Jul 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Biological effects of laser-accelerated proton bursts

  Odložilík, B. (Author), Borghesi, M. (Supervisor) & Prise, K. (Supervisor), Dec 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

  File

• Biophysical correlates of base-mediated radiation cardiotoxicity in non-small cell lung cancer

  Walls, G. M. (Author), Butterworth, K. (Supervisor), Jain, S. (Supervisor) & Cole, A. (Supervisor), Jul 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

  File

• CaV1.3 Ion channel expression and hormone therapy in prostate cancer

  McKerr, N. (Author), McCloskey, K. (Supervisor) & Mills, I. (Supervisor), Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Characterisation of calcium/calmodulin-dependent protein kinase kinase 2 in prostate cancer

  Stewart, L. (Author), Waugh, D. (Supervisor), Mills, I. (Supervisor) & Evergren Mills, E. (Supervisor), Jul 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Characterisation of novel molecular subtypes and corresponding pre-clinical models in AML, with implications for treatment response.

  Strain, P. (Author), Blayney, J. (Supervisor) & Mills, K. (Supervisor), Jul 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Characterisation of oncogenic pathways driving the pathogenesis of prostate cancer

  Ormrod, A. (Author), Mullan, P. (Supervisor) & Wilson, M. (Supervisor), Dec 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Characterisation of ZFP36L1, a novel breast cancer predisposition gene

  Winter, T. (Author), Orr, N. (Supervisor) & Jafarnejad Shourkaei, S. M. (Supervisor), Jul 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Characterising pathways driving aggressive biology and chemoresistance in triple negative breast cancers biology and chemoresistance in triple negative breast cancers

  McBrien, C. (Author), Buckley, N. (Supervisor) & Mullan, P. (Supervisor), Jul 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Clinical, genetic and molecular correlations in pituitary neuroendocrine tumours

  Loughrey, P. B. (Author), James, J. (Supervisor), Craig, S. (Supervisor), Korbonits, M. (Supervisor) & Hunter, S. (Supervisor), Dec 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Cross-dataset transcription-based quality control for tumour samples and pre-clinical models

  Brown, N. (Author), Kennedy, R. (Supervisor) & Blayney, J. (Supervisor), Jul 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Defining the clinical importance of epithelial-stroma-immune signalling in colorectal cancer using a molecular pathology approach

  McCorry, A. (Author), Lawler, M. (Supervisor), Dunne, P. (Supervisor) & Salto-Tellez, M. (Supervisor), Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Delineating mechanisms which underlie differential cell fates induced by p53 activation and HDAC inhibition in colorectal cancer

  Lees, A. (Author), McDade, S. (Supervisor) & Longley, D. (Supervisor), Dec 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Designing integrative big data analytical frameworks to accelerate precision oncology

  Senevirathne, S. (Author), Dunne, P. (Supervisor), McArt, D. (Supervisor) & Longley, D. (Supervisor), Jul 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Determining effective radiation / drug combinations for paediatric cancers

  McGill, A. (Author), Prise, K. (Supervisor) & Mills, K. (Supervisor), Jul 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Developing computational methods to enhance understanding in glioma progression

  Roddy, A. (Author), McArt, D. (Supervisor), Prise, K. (Supervisor) & Salto-Tellez, M. (Supervisor), Jul 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of Novel Antibody-Targeted Nanoparticle Strategies for Treatment of Pancreatic Cancer

  Johnston, M. (Author), Longley, D. (Supervisor) & Scott, C. (Supervisor), Jul 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Development of novel polymeric nanoparticles for pancreatic cancer therapy

  Leach, A. (Author), Scott, C. (Supervisor) & Longley, D. (Supervisor), Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Development of novel therapeutics for the treatment of pancreatic cancer

  Nicoll, J. (Author), Scott, C. (Supervisor) & Longley, D. (Supervisor), Dec 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Development of orthogonal nanotherapeutics for colorectal cancer treatment

  Abed, A. (Author), Bell, S. (Supervisor) & Scott, C. (Supervisor), Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy