• 97 Lisburn Road, Medical Biology Centre

    BT9 7BL Belfast

    United Kingdom

Research Output 1970 2020

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Meeting abstract
2019

Altering the balance of Rho GTPase pathways in CLL determines CLL cell fate

Samir, Y., Rees-Unwin, K., Graham, C., Graham, R., Rahi, R., Adams, J. & Burthem, J., 27 Mar 2019, In : British Journal of Haematology. 185, S1, p. 171-172

Research output: Contribution to journalMeeting abstract

Assessment of novel disinfection technologies, and bacterial contamination in the healthcare setting

Murray, J., Ternan, N., Gill, C., McMullan, G., Farren, D. & Scott, M., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access

Non-sporulating variants of C. difficile from animal faecal samples

Vardy, N., McGrath, J., Fairley, D., McMullan, G. & Connor, M., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access

Poster abstract: Leveraging structural relationships as a novel mode of viral classification

Magill, D., Skvortsov, T., O’Flaherty, V. & McGrath, J., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access
phylogenetics
protein
gene
holistic approach
bacteriophage

Poster abstract: Understanding the evolution and metabolic capabilities of the Butyrivibrio group

Pidcock, S., Skvortsov, T., Santos, F., Ting, K. S., Creevey, C. & Huws, S., 01 Mar 2019, In : Access Microbiology. 1, 1A, 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
Butyrivibrio
Pseudobutyrivibrio
genome
glycosidases
biohydrogenation

WS06-1 Initial results evaluating combinations of the novel CFTR corrector PTI-801, potentiator PTI-808, and amplifier PTI-428 in cystic fibrosis subjects

Downey, D., Flume, P., Jain, M., Fajac, I., Schwarz, C., Pressler, T., Van Koningsbruggen-Rietschel, S., Taylor-Cousar, J., Horsley, A., Sutharsan, S., Miller, J., Poirier, G., Jiang, J., Inoue, T., Wilson, S., Lee, P-S. & Gilmartin, G., Jun 2019, In : Journal of Cystic Fibrosis. 18, Suppl 1, p. S10 1 p.

Research output: Contribution to journalMeeting abstract

2018

Bioactive Compounds in Fenugreek Ameliorate ER Stress and VLDL Overproduction via the Mediation of Insig Signaling

Khound, R. & Su, Q., 12 Mar 2018, In : Arteriosclerosis Thrombosis and Vascular Biology. 38, Suppl_1, p. A178 1 p.

Research output: Contribution to journalMeeting abstract

Trigonella
Endoplasmic Reticulum Stress
Seeds
Liver
Sterol Regulatory Element Binding Protein 1
13 Citations (Scopus)

MicroRNAs and Hedgehog Signaling in the Pathogenesis of Progressive Liver Injury from NAFLD to Fibrosis

Cheng, X. & Su, Q., 12 Mar 2018, In : Arteriosclerosis Thrombosis and Vascular Biology. 38, Suppl_1, p. A601 1 p.

Research output: Contribution to journalMeeting abstract

Hedgehogs
MicroRNAs
Fibrosis
Liver Cirrhosis
Liver
2017
eIF-2 Kinase
MicroRNAs
Insulin Resistance
Liver
3' Untranslated Regions

Acute Phase Response Transcription Factor CREBH Mediates Metabolic Inflammation to Hepatic VLDL Overproduction and Hyperlipidemia

Song, Y., Zhao, M., Khound, R. & Su, Q., 25 Aug 2017, In : Arteriosclerosis Thrombosis and Vascular Biology. 37, Supplement 1, 1 p., A196.

Research output: Contribution to journalMeeting abstract

Open Access
STAT3 Transcription Factor
VLDL Lipoproteins
Hyperlipidemias
Apolipoproteins B
Carrier Proteins

A Novel Family Of Kunitz-type Inhibitors From Fasciola Hepatica-potent Inhibition Of Virulence-associated Cysteine Proteases

Smith, D., Tikhonova, I., Drysdale, O., Dvorak, J., Robinson, M., Cwiklinski, K. & Dalton, J., 01 Nov 2017, In : AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 95, Supplement 2017, p. 568 1 p.

Research output: Contribution to journalMeeting abstract

Cytoplasmic glycosylation of clathrin-mediated endocytosis signalling components alters the rate of iron uptake by placenta of mothers with type 2 diabetes

Palin, V., Russell, M., Graham, R., Aplin, J. & Westwood, M., 30 Aug 2017, In : Placenta. 57, p. 300-301 2 p., P2.26.

Research output: Contribution to journalMeeting abstract

GLP-1 Mediates the Intrinsic Gut-Liver Metabolic Signaling in Anti-VLDL Overproduction and Insulin Resistance in Vagotomized Mice

Khound, R. & Su, Q., 01 Apr 2017, In : The FASEB Journal. 31, No. 1_supplement, p. 137.1 1 p.

Research output: Contribution to journalMeeting abstract

Glucagon-Like Peptide 1
VLDL Lipoproteins
Liver
Insulin Resistance
Insulin

MicroRNAs in the Pathogenesis of Lipogenic Diet Induced Hyperlipidemia and Insulin Resistance

Su, Q., Sud, N. & Pan, K., 01 Apr 2017, In : The FASEB Journal. 31, No. 1_supplement, p. 299.8 1 p.

Research output: Contribution to journalMeeting abstract

Nutrition
Hyperlipidemias
MicroRNAs
Insulin Resistance
Insulin
9 Citations (Scopus)

Plasma ghrelin and obestatin levels are altered in a pre-diabetic rat model exhibiting established obesity and hypertension

Calderwood, D., Agnew, A., Grieve, D. & Green, B., 08 Mar 2017, In : Diabetic Medicine. 34, Supplement 1, p. 51-54 4 p.

Research output: Contribution to journalMeeting abstract

Ghrelin
Obesity
Hypertension
Hormones
Body Weight

Steered Molecular Dynamic Simulations Reveal Critical Residues for (Un) Binding of Substrates, Inhibitors and a Product of the Malarial PFM1AAP

Moore, D. S., Dalton, J. P. & Tikhonova, I. G., 03 Feb 2017, In : Biophysical Journal. 112, 3 (Supplement 1), p. 354a 1 p.

Research output: Contribution to journalMeeting abstract

CD13 Antigens
Antimalarials
Molecular Dynamics Simulation
Plasmodium falciparum
Growth and Development
2016

A Universal Surface for Label-Free Electrical and Optical Sensing of Disease Markers

Tsai, M-Y., Tarasov, A., Gray, D. W., Shields, N., Creedon, N., Montrose, A., Flynn, E. M., Joiner, C. A., Taylor, R., Lovera, P., O'Riordan, A., Mooney, M. H. & Vogel, E. M., 30 Jun 2016, In : ECS Meeting Abstracts. MA2016-01, 2018

Research output: Contribution to journalMeeting abstract

Open Access

Fenugreek Seeds Inhibit Hepatic VLDL Overproduction by Attenuating Metabolic Inflammatory Stress

Shen, J. & Su, Q., May 2016, In : Arteriosclerosis Thrombosis and Vascular Biology. 36, Suppl_1, p. A215 1 p.

Research output: Contribution to journalMeeting abstract

Trigonella
VLDL Lipoproteins
Seeds
Liver
Insulin Resistance
45 Citations (Scopus)
LDL Receptors
Hyperlipidemias
Triglycerides
Carrier Proteins
Chylomicrons
2 Citations (Scopus)

Rapid-bTB: a novel lateral flow device able to differentiate Mycobacterium bovis from Mycobacterium tuberculosis in sputum

Stewart, L., Grant, I., Sander, M. & Egbe, F., Dec 2015, In : The International Journal of Tuberculosis and Lung Disease. 19, 12 (Supplement 2), p. S3-S4 2 p.

Research output: Contribution to journalMeeting abstract

The cAMP Responsive Element Binding Protein H Links Metabolic Inflammation with Hyperlipidemia in Hepatic Insulin Resistance

Zhao, M. & Su, Q., 01 Apr 2015, In : The FASEB Journal. 29, No. 1_supplement, p. 393.7 1 p.

Research output: Contribution to journalMeeting abstract

Hyperlipidemias
Insulin Resistance
Carrier Proteins
Insulin
VLDL Lipoproteins
2014

Activation of Hepatic CREBH-Insig-2a Signaling in the Triglyceride-Lowering Mechanism of R-Alpha-Lipoic Acid

Tong, X. & Su, Q., 17 Apr 2014, In : Arteriosclerosis Thrombosis and Vascular Biology. 34, Suppl_1, p. A440 1 p.

Research output: Contribution to journalMeeting abstract

Thioctic Acid
Carrier Proteins
Triglycerides
Liver
VLDL Lipoproteins

A Novel Human In Vitro Model for the Study of Nociceptive Responses in Sensory Nerves

Clarke, R., Monaghan, K., Curtis, T. A., Cosby, L. S., Lundy, F. T. & McGarvey, L., 01 Feb 2014, In : Lung. 192, 1, p. 4-5 2 p.

Research output: Contribution to journalMeeting abstract

BRCA1 as a regulator of global cell metabolism - identifying functional targets through integromic analysis

Powell, A., Savage, K. I. & Harkin, D. P., Jul 2014, In : European Journal of Cancer. 50, 5, p. S77 1 p.

Research output: Contribution to journalMeeting abstract

Exposure to aflatoxin from groundnut among Senegalese adults

Watson, S., Atehnkeng, J., Diedhiou, P. M., Bandyopadhyay, R., Srey, C., Wild, C. P. & Gong, Y. Y., Jan 2014, In : Proceedings of the Nutrition Society. 73, OCE2, 1 p., E98.

Research output: Contribution to journalMeeting abstract

Pregnancy planning indicators following the implementation of an educational pre-conception counselling resource (DVD) for women with diabetes into routine care in Northern Ireland: a service evaluation

Holmes, VA., Hamill, LL., Spence, M., Alderdice, FA., Patterson, CC., Harper, R., Loughridge, S., McKenna, S. & McCance, DR., Mar 2014, In : Diabetic Medicine. 31, Suppl. 1, p. 8 1 p.

Research output: Contribution to journalMeeting abstract

WS2. 9 Inflammatory potential and antimicrobial susceptibility of bacteria in the cultivatable CF lung microbiome

Hatch, J., Kim, JD., McGrath, SJ., McIlreavey, L., Gilpin, DF., Lavelle, GM., Murray, M., Boucher, RC., Elborn, JS., McElvaney, NG., Muhlebach, M., Tunney, M., Wolfgang, M. C. & Randell, S. H., Jun 2014, In : Journal of Cystic Fibrosis. 13, Supplement 2, p. S5

Research output: Contribution to journalMeeting abstract

Bladder cancer diagnostic algorithms in hematuria populations.

Stevenson, M., Reid, C., Duggan, B., Ruddock, M. & Williamson, K. E., 15 Apr 2013, In : Cancer Research. 73, 8, 1 p.

Research output: Contribution to journalMeeting abstract

Consensus and confusion in molluscan phylogeny

Sigwart, J. D. & Schroedl, M., Apr 2013, In : INTEGRATIVE AND COMPARATIVE BIOLOGY. 53, p. E198-E198 1 p.

Research output: Contribution to journalMeeting abstract

Consumer views of portion size estimation aids

Faulkner, G. P., Pourshahidi, L. K., Dean, M., Spence, M., O'Brien, S., Gibney, E., Kerr, MA., McCaffrey, TA., Wallace, JMW. & Livingstone, MBE., Jan 2013, In : Proceedings of the Nutrition Society. 72, OEC3 , p. E169 72 (OCE3).

Research output: Contribution to journalMeeting abstract

Open Access
File
14 Citations (Scopus)

Environmentally-driven changes to metabolic scaling relationships in grazing mollusks

Carey, N. & Sigwart, J. D., Apr 2013, In : INTEGRATIVE AND COMPARATIVE BIOLOGY. 53, p. E258-E258 1 p.

Research output: Contribution to journalMeeting abstract

Evaluating the anti-diabetic potential of several species of Malaysian seaweed.

Green, B., Chin, Y. X., Lim, P., Maggs, C., Phang, S. M. & Sharifudfin, Y., 2013, In : The Phycologist. 85, 3, p. 16

Research output: Contribution to journalMeeting abstract

Functional morphology in chitons (Polyplacophora): influences of environment and ocean acidification

Green, P. A., Crofts, S. & Sigwart, J. D., Apr 2013, In : INTEGRATIVE AND COMPARATIVE BIOLOGY. 53, p. E290-E290 1 p.

Research output: Contribution to journalMeeting abstract

17 Citations (Scopus)

Gestational diabetes: things you need to know (but maybe don't): development of an educational DVD for women recently diagnosed with gestational diabetes

Whittle, C., McCance, D. R., Maresh, M., Harper, R., Alderdice, F. A., Quinn, S., Quinn, J., Curtis, S., Thomas, L., Spence, M., Davies, M., Hughes, C., McCourt, T., Patterson, C. & Holmes, V., Mar 2013, In : Diabetic Medicine. 30, p. 123-124 2 p.

Research output: Contribution to journalMeeting abstract

Insig-2a Links CREBH Signaling to Hepatic Lipogenesis and Systemic Hyperlipidemia

Wang, H. & Su, Q., 17 Mar 2013, In : Arteriosclerosis Thrombosis and Vascular Biology. 33, Suppl_1, p. A434 1 p.

Research output: Contribution to journalMeeting abstract

Lipogenesis
Hyperlipidemias
Carrier Proteins
Protein Isoforms
Insulin

In vitro modulation of GLP-1 activity by different aqueous and organic extracts of edible seaweeds.

Schultz Moreira, A., Rafferty, E., Green, B., Garcimartin, A., Benedi, J., Bastida, S. & Sanchez-Muniz, FJ., 2013, In : Annals of Nutrition and Metabolism. 63, 1, p. 1674

Research output: Contribution to journalMeeting abstract

Metabolic signatures of human Alzheimer’s disease (AD): 1H NMR analysis of the polar metabolome in post-mortem brain tissue.

Graham, S., Holscher, C. & Green, B., 2013, In : Metabolomics.

Research output: Contribution to journalMeeting abstract

Untargeted metabolomics methods for the early detection of Alzheimer’s disease (AD): potential for developing new diagnostics?

Graham, S., Chevallier, O., McGuiness, B., Holscher, C., Kehoe, P. G., Elliott, C., Passmore, A. & Green, B., 2013, In : Metabolomics.

Research output: Contribution to journalMeeting abstract

2012

An exploration of consumer barriers to healthy portion control on the island of Ireland

Spence, M., Dean, M. & Livingstone, M. B. E., 2012, In : Proceedings of the Nutrition Society. p. E212 71 (OCE2).

Research output: Contribution to journalMeeting abstract

Breaking DNA and killing cells with exotic types of radiation

Schettino, G., Timson, D. J., Currell, F. J. & Kavanagh, J. N., 2012, In : International Journal of Molecular Medicine. 30, p. S12-S12 1 p.

Research output: Contribution to journalMeeting abstract

Current Alzheimer’s Research at Queen’s University, Belfast.

Graham, S., Elliott, C. & Green, B., 2012, In : Northern Ireland Affairs Committee.

Research output: Contribution to journalMeeting abstract

2011

Bacterial Diversity of the Colonic Microbiota in De-Novo Extensive Paediatric Ulcerative Colitis by Next-Generation Sequencing

Hansen, R., Reiff, C., Russell, R. K., Bisset, W. M., Berry, S. H., Mukhopadhya, I., Thomson, J. M., El-Omar, E. & Hold, G. L., May 2011, In : Gastroenterology. 140, 5, p. S196-S196 1 p.

Research output: Contribution to journalMeeting abstract