School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

2019
1 Citation (Scopus)

123I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults

Roberts, G., Lloyd, J. J., Petrides, G. S., Donaghy, P., Kane, J., Durcan, R., Lawley, S., Howe, K., Sims, A., Taylor, J-P., O'Brien, J. T. & Thomas, A. J., 21 Mar 2019, In : Annals of Nuclear Medicine.

Research output: Contribution to journalArticle

Corpus Striatum
Lewy Body Disease
Nortropanes
Software
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
4 Citations (Scopus)

123I-MIBG scintigraphy utility and cut-off value in a clinically representative dementia cohort

Kane, J. P. M., Roberts, G., Petrides, G. S., Lloyd, J. J., O'Brien, J. T. & Thomas, A. J., 26 Jan 2019, In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

3-Iodobenzylguanidine
Radionuclide Imaging
Dementia
Mediastinum
Lewy Body Disease
1 Citation (Scopus)

2-hydroxylation of Acinetobacter baumannii lipid A contributes to virulence

Bartholomew, T. L., Kidd, T. J., Sá Pessoa, J., Conde Álvarez, R. & Bengoechea, J. A., 25 Mar 2019, In : Infection and Immunity.

Research output: Contribution to journalArticle

Open Access
File
Acinetobacter baumannii
Lipid A
Hydroxylation
Virulence
Interleukin-10

A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions

McGarry, C., McCreery, C., Jeevanandam, P., King, R., Hounsell, A., Jain, S. & Buchanan, F., 27 Jun 2019.

Research output: Contribution to conferenceAbstract

Pelvis
Prostate
Bone and Bones
Prostatic Neoplasms
Radiotherapy

Abstract: Incorporation of spiritual care as a component of healthcare and medical education: viewpoints of healthcare providers and trainees In Nepal

Hacking, L., Harbinson, M. & Bell, D., 02 May 2019, Global Health Symposium Abstracts. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nepal
Medical Education
Health Personnel
Delivery of Health Care
Nurses

A Case of Transient Diplopia and Ophthalmoplegia Following Dental Anesthesia

Peto, T., Seres, L., Petho, G. & Peto, Z., 14 Aug 2019, In : Nigerian Journal of Clinical Practice.

Research output: Contribution to journalArticle

Open Access
File
Dental Anesthesia
Ophthalmoplegia
Diplopia
Dentists
Patient Care
1 Citation (Scopus)

A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells

Winning, L., El Karim, I. A. & Lundy, F. T., 01 Aug 2019, In : Stem Cells and Development. 28, 15, p. 1050-1058 9 p.

Research output: Contribution to journalArticle

Dental Pulp
Mesenchymal Stromal Cells
Deciduous Tooth
Tooth
Periodontal Ligament

A Comparison of Inpatient and Outpatient-Based Chemotherapy Regimens for the Treatment of Acute Myeloid Leukaemia In The Elderly

Daly, A. B., Cuthbert, R., Finnegan, D., Arnold, C., Craddock, C. & McMullin, M. F., Jan 2019, In : The Ulster Medical Journal. 88, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

Open Access
File
Acute Myeloid Leukemia
Inpatients
Outpatients
Drug Therapy
Survival
1 Citation (Scopus)

A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma

Wong, R. K. Y., MacMahon, M., Woodside, J. V. & Simpson, D. A., 03 Jun 2019, In : BMC Genomics. 20, 12 p., 446.

Research output: Contribution to journalArticle

Open Access
File
RNA Sequence Analysis
MicroRNAs
RNA
Libraries
Biomarkers
1 Citation (Scopus)

A comparison of visual and semiquantitative analysis methods for planar cardiac 123I-MIBG scintigraphy in dementia with Lewy bodies

Roberts, G., Kane, J., Lloyd, J. J., Petrides, G. S., Howe, K., O'Brien, J. T. & Thomas, A. J., 02 May 2019, In : Nuclear Medicine Communications.

Research output: Contribution to journalArticle

A Core Outcome Set for Critical Care Ventilation Trials

Blackwood, B., Ringrow, S., Clarke, M., Marshall, J. C., Connolly, B., Rose, L. & McAuley, D. F., 25 Jul 2019, In : Critical Care Medicine.

Research output: Contribution to journalArticle

Open Access
File
Delphi Technique
Ventilation
Clinical Trials
Critical Care
Artificial Respiration
Germinal Center
B-Lymphocytes
Antibodies
Lymphopenia
Vaccination
2 Citations (Scopus)

Acute and chronic hypoxia differentially predispose lungs for metastases

Reiterer, M., Colaço, R., Emrouznejad, P., Jensen, A., Rundqvist, H., Johnson, R. S. & Branco, C., 15 Jul 2019, In : Scientific Reports. 9, 15 p., 10246.

Research output: Contribution to journalArticle

Open Access
File
Endothelial cells
Neoplasm Metastasis
Lung
Tumors
Endothelial Cells

Adaptive radiotherapy for head and neck cancer reduces the requirement for rescans during treatment due to spinal cord dose

Belshaw, L., Agnew, C. E., Irvine, D. M., Rooney, K. & McGarry, C., 01 Nov 2019, In : Radiation Oncology.

Research output: Contribution to journalArticle

Open Access
File
Cone-Beam Computed Tomography
Head and Neck Neoplasms
Spinal Cord
Radiotherapy
Workload

Adjustment strategies amongst black African and black Caribbean men following treatment for prostate cancer: findings from the Life After Prostate Cancer Diagnosis (LAPCD) study

Wagland, R., Nayoan, J., Matheson, L., Rivas, C., Brett, J., Collaço, N., Alexis, O., Gavin, A., Glaser, A. W. & Watson, E., 23 Oct 2019, In : European Journal of Cancer Care. 9 p., e13183.

Research output: Contribution to journalArticle

Social Adjustment
Prostatic Neoplasms
Therapeutics
Masculinity
Patient-Centered Care

A feasibility study of ‘The StepSmart Challenge’ to promote physical activity in adolescents

Corepal, R., Best, P., O'Neill, R., Kee, F., Badham, J., Dunne, L., Miller, S., Connolly, P., Cupples, M., van Sluijs, E. M. F., Tully, M. & Hunter, R. F., 17 Nov 2019, In : Pilot and Feasibility Studies. 5, 15 p., 132.

Research output: Contribution to journalArticle

Open Access
File
Feasibility Studies
Exercise
Reward
Social Support
Northern Ireland

A foundation in acute paediatrics (FAPS) – enhancing perceptions of paediatrics and stimulating speciality recruitment using a simulation recruiter course

Mallett, P., Junk, C., Flannigan, C., Fitzsimons, A., Thompson, A. & Bourke, T., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A253-A254 G626P.

Research output: Contribution to journalMeeting abstract

2 Citations (Scopus)

A Four-Group Urine Risk Classifier for Predicting Outcome in Prostate Cancer Patients

Movember GAP1 Urine Biomarker Consortium, 20 May 2019, In : BJU International.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Urine
Prostate
RNA
Biopsy
2 Citations (Scopus)

A framework for characterising and evaluating the effectiveness of environmental modelling

Hamilton, S. H., Fu, B., Guillaume, J. H. A., Badham, J., Elsawah, S., Gober, P., Hunt, R. J., Iwanaga, T., Jakeman, A. J., Ames, D. P., Curtis, A., Hill, M. C., Pierce, S. A. & Zare, F., 01 Aug 2019, In : Environmental Modelling and Software. 118, p. 83-98 16 p.

Research output: Contribution to journalArticle

environmental modeling
accessibility
modeling
evaluation

A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans

Mohamed, Y. F., Scott, N. E., Molinaro, A., Creuzenet, C., Ortega, X., Lertmemongkolchai, G., Tunney, M. M., Green, H., Jones, A. M., DeShazer, D., Currie, B. J., Foster, L. J., Ingram, R., De Castro, C. & Valvano, M. A., 26 Jul 2019, In : The Journal of biological chemistry.

Research output: Contribution to journalArticle

Open Access
File
Burkholderia
Glycosylation
Machinery
Polysaccharides
Burkholderia cenocepacia
9 Citations (Scopus)

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Lux, F., Tran, V. L., Thomas, E., Dufort, S., Rossetti, F., Martini, M., Truillet, C., Doussineau, T., Bort, G., Denat, F., Boschetti, F., Angelovski, G., Detappe, A., Crémillieux, Y., Mignet, N., Doan, B-T., Larrat, B., Meriaux, S., Barbier, E., Roux, S. & 28 othersFries, P., Müller, A., Abadjian, M-C., Anderson, C., Canet-Soulas, E., Bouziotis, P., Barberi-Heyob, M., Frochot, C., Verry, C., Balosso, J., Evans, M., Sidi-Boumedine, J., Janier, M., Butterworth, K., McMahon, S., Prise, K., Aloy, M-T., Ardail, D., Rodriguez-Lafrasse, C., Porcel, E., Lacombe, S., Berbeco, R., Allouch, A., Perfettini, J-L., Chargari, C., Deutsch, E., Le Duc, G. & Tillement, O., 01 Jan 2019, In : British Journal of Radiology. 92, 1093, 19 p., 20180365.

Research output: Contribution to journalArticle

Open Access
File
Clinical Medicine
Gadolinium
Nanoparticles
Radiation-Sensitizing Agents
Siloxanes

A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., 13 Nov 2019, In : Stem Cells.

Research output: Contribution to journalArticle

Histone Deacetylases
Blood Vessels
Regeneration
Phosphorylation
Amino Acids
Respiratory Syncytial Virus Infections
Chemokines
Epithelium
Cytokines
Infection

Airway surface liquid has innate antiviral activity that is reduced in cystic fibrosis

Berkebile, A. R., Bartlett, J. A., Alaiwa, M. A., Varga, S. M., Power, U. & McCray, P. B., 26 Jun 2019, In : American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journalArticle

Open Access
File
Cystic Fibrosis
Antiviral Agents
Viruses
Liquids
Fibrosis

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications

Hill, M., Twigg, M., Sheridan, E. A., Hardy, J. G., Elborn, J. S., Taggart, C. C., Scott, C. J. & Migaud, M. E., 02 Aug 2019, In : Pharmaceutics. 11, 8, 12 p., 379.

Research output: Contribution to journalArticle

Open Access
File
Tobramycin
Chitosan
Mucus
Drug Delivery Systems
Cystic Fibrosis

A loyalty scheme to encourage physical activity in office workers: a cluster RCT

Hunter, R., Gough, A., Murray, J., Tang, J., Brennan, S., Chrzanowski-Smith, O., Carlin, A., Patterson, C., Longo, A., Hutchinson, W. G., Prior, L., Tully, M., French, D., Adams, J., McIntosh, E., Xin, Y. & Kee, F., Aug 2019, In : Public Health Research. 7, 15, 114 p.

Research output: Contribution to journalSpecial issue

Open Access
File
Workplace
Quality-Adjusted Life Years
Cost-Benefit Analysis
Absenteeism
Waiting Lists
Macular Edema
Clinical Trials
Light Coagulation
Therapeutics
Lasers
2 Citations (Scopus)

Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability

Liberante, F. G., Lappin, K., Barros, E. M., Vohhodina, J., Grebien, F., Savage, K. I. & Mills, K. I., 25 Feb 2019, In : Scientific Reports. 9, 13 p., 2678.

Research output: Contribution to journalArticle

Open Access
File
Amino Acyl-tRNA Synthetases
Azaguanine
Myelodysplastic Syndromes
Mutation
RNA Splicing

A Machine Learning Platform to Optimize the Translation of Personalized Network Models to the Clinic

Salvucci, M., Rahman, A., Resler, A. J., Udupi, G. M., McNamara, D. A., Kay, E. W., Laurent-Puig, P., Longley, D. B., Johnston, P. G., Lawler, M., Wilson, R., Salto-Tellez, M., Van Schaeybroeck, S., Rafferty, M., Gallagher, W. M., Rehm, M. & Prehn, J. H. M., 17 Apr 2019, In : JCO Clinical Cancer Informatics. 17 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Array Analysis
Colorectal Neoplasms
Proteins
Immunohistochemistry
Workflow
1 Citation (Scopus)

A magnetic self-contained thermochromic system with convenient temperature range

Billeci, F., Gunaratne, H. Q., D'Anna, F., Morgan, G., Seddon, K. R. & Plechkova, N., 2019, In : Green Chemistry. 21, 6, p. 1412-1416 5 p.

Research output: Contribution to journalArticle

Ionic Liquids
Ionic liquids
volatile substance
Cobalt
Polymer films

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A. E., Doney, A. S., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 05 Mar 2019, In : Scientific Reports. 9, 10 p., 3591.

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
Biomarkers
Blood Pressure
HDL Lipoproteins
1 Citation (Scopus)

Analysis of KRAS, NRAS, BRAF, PIK3CA and TP53 mutations in a large prospective series of locally advanced rectal cancer patients

Sclafani, F., Hulkki Wilson, S., Cunningham, D., Gonzalez De Castro, D., Kalaitzaki, E., Begum, R., Wotherspoon, A., Capdevila, J., Glimelius, B., Roselló, S., Thomas, J., Tait, D., Brown, G., Oates, J. & Chau, I., 14 Jun 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Rectal Neoplasms
Mutation
Disease-Free Survival
Neoplasms
Neoplasm Genes
Open Access
File
Medical Students
Motivation
Anatomy
Students
Research
interdependence
classroom
Group
self-regulation
self-esteem
4 Citations (Scopus)

An evaluation of techniques for dose calculation on cone beam computed tomography

Giacometti, V., King, R. B., Agnew, C. E., Irvine, D. M., Jain, S., Hounsell, A. R. & McGarry, C. K., 26 Feb 2019, In : British Journal of Radiology. 92, 1096, 11 p., 20180383.

Research output: Contribution to journalArticle

Cone-Beam Computed Tomography
Calibration
Radiotherapy
Prostate
Neck

An evaluation of the impact of environmental priming on clinical performance in simulated paediatric emergencies – a randomised controlled trial

McNaughten, B., Storey, L., Corkin, D., Cardwell, P., Thompson, A., Bourke, T. & O'Donoghue, D., 01 May 2019, In : Archives of Disease in Childhood. 104, Suppl 2, p. A252

Research output: Contribution to journalMeeting abstract

Open Access
File
Caregivers
Renal Dialysis
Chronic Renal Insufficiency
Saudi Arabia
Interviews

An Integrative Biomedical Informatics Approach to Elucidate the Similarities Between Pre-Eclampsia and Hypertension

Lopez-Campos, G., Bonner, E. & McClements, L., 21 Aug 2019, In : Studies in Health Technology and Informatics. 264, p. 988-992 5 p.

Research output: Contribution to journalArticle

Open Access
File
Prehypertension
Informatics
Oxidative stress
Immune system
Bioinformatics

A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases.

Li, M., Keenan, C. R., Lopez Campos, G., Mangum, J. E., Chen, Q., Prodanovic, D., Xia, Y. C., Langenbach, S. Y., Harris, T., Hofferek, V., Reid, G. E. & Stewart, A. G., 22 Feb 2019, In : iScience. 12, p. 232-246

Research output: Contribution to journalArticle

Open Access
File
Transforming Growth Factors
Glucocorticoids
Steroids
Phospholipase D
Lim Kinases

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In : Journal of Oncology.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
Triple Negative Breast Neoplasms
Biomarkers
Neoplasms
DNA Repair
athlete
professional sports
road
cause

An RCT of atraumatic restorative treatment for older adults: 5 year results

Da Mata, C., McKenna, G., Anwigi, L., Hayes, M., Woods, N., O'Mahony, D. & Allen, PF., 09 Mar 2019, In : Journal of Dentistry. 5 p.

Research output: Contribution to journalArticle

Survival
Survival Rate
Dental Care
Therapeutics
Dentists

Antidepressant medication use among working age first-generation migrants resident in Finland : an administrative data linkage study

Bosqui, T., Väänänen, A., Buscariolli, A., Koskinen, A., O'Reilly, D., Airila, A. & Kouvonen, A., 16 Oct 2019, In : International Journal of Equity in Health. 18, 1, p. 157

Research output: Contribution to journalArticle

Open Access
File
Information Storage and Retrieval
Finland
Antidepressive Agents
Prescriptions
Mental Health

A nurse-led, preventive, psychological intervention to reduce PTSD symptom severity in critically ill patients: the POPPI feasibility study and cluster RCT

Mouncey, P. R., Wade, D. M., Richards-Belle, A., Sadique, Z., Wulff, J., Grieve, R., Emerson, L., Brewin, C. R., Harvey, S., Howell, D., Hudson, N., Khan, I., Mythen, M., Smyth, D., Weinman, J., Welch, J. J., Harrison, D. & Rowan, K. M., 01 Aug 2019, In : Health Services and Delivery Research. 7, 30, 206 p.

Research output: Contribution to journalArticle

Open Access
File
Feasibility Studies
Post-Traumatic Stress Disorders
Critical Illness
Randomized Controlled Trials
Nurses

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 06 Sep 2019, In : Molecular Psychiatry. 16 p.

Research output: Contribution to journalArticle

Open Access
File
Schizophrenia
Disease Resistance
Penetrance
Genomics
Psychiatry

Application of 1H-NMR Metabolomics for the Discovery of Blood Plasma Biomarkers of a Mediterranean Diet

Macias, S., Kirma, J., Yilmaz, A., Moore, S. E., McKinley, M. C., McKeown, P. P., Woodside, J. V., Graham, S. F. & Green, B. D., 27 Sep 2019, In : Metabolites. 9, 10, 14 p., 201.

Research output: Contribution to journalArticle

Open Access
File
Mediterranean Diet
Metabolomics
Biomarkers
Nutrition
Blood
9 Citations (Scopus)

Application of high-sensitivity troponin in suspected myocardial infarction

Neumann, J. T., Twerenbold, R., Ojeda, F., Sörensen, N. A., Chapman, A. R., Shah, A. S. V., Anand, A., Boeddinghaus, J., Nestelberger, T., Badertscher, P., Mokhtari, A., Pickering, J. W., Troughton, R. W., Greenslade, J., Parsonage, W., Mueller-Hennessen, M., Gori, T., Jernberg, T., Morris, N., Liebetrau, C. & 34 othersHamm, C., Katus, H. A., Münzel, T., Landmesser, U., Salomaa, V., Iacoviello, L., Ferrario, M. M., Giampaoli, S., Kee, F., Thorand, B., Peters, A., Borchini, R., Jørgensen, T., Söderberg, S., Sans, S., Tunstall-Pedoe, H., Kuulasmaa, K., Renné, T., Lackner, K. J., Worster, A., Body, R., Ekelund, U., Kavsak, P. A., Keller, T., Lindahl, B., Wild, P., Giannitsis, E., Than, M., Cullen, L. A., Mills, N. L., Mueller, C., Zeller, T., Westermann, D. & Blankenberg, S., 27 Jun 2019, In : New England Journal of Medicine. 380, 26, p. 2529-2540 12 p.

Research output: Contribution to journalArticle

Troponin
Myocardial Infarction
Troponin I
Hospital Emergency Service
Troponin T

A public dialogue on genomic medicine: time for a new social contract?

Castell, S., Bukowski, G. & McAneney, H., 25 Apr 2019, Ipsos MORI.

Research output: Book/ReportCommissioned report

Open Access
File