School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Whitla Medical Building

    BT9 7BL Belfast

    United Kingdom

Research Output

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2020

An Interpretable Semi-supervised Classifier using Rough Sets for Amended Self-labeling

Grau, I., Sengupta, D., Lorenzo, M. M. G. & Nowé, A., 20 Mar 2020, (Accepted) Proceedings of IEEE International Conference on Fuzzy Systems. IEEE

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

Abstract: Incorporation of spiritual care as a component of healthcare and medical education: viewpoints of healthcare providers and trainees In Nepal

Hacking, L., Harbinson, M. & Bell, D., 02 May 2019, Global Health Symposium Abstracts. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Combined LC-MS and 1H-NMR metabolomic profiling uncovers dietary biomarkers in a cohort of healthy Northern Irish older adults

Rosas da Silva, G., Graham, S., Ugur, Z., Yilmaz, A., Kee, F., Young, I., Woodside, J., Neville, C., McEvoy, C. & Green, B., 2019, Federation of the European Nutrition Societies (FENS) Conference (October 15-18 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Published abstract: Assessing alterations in organelle contacts during prostate cancer development

Evergren, E. & Butler, L., 09 Dec 2019, Oncology Abstracts. BioScientifica Ltd., Vol. 1. 1 p. P018

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

WS19-3 Microbiota profiling during 1-year of clinical stability in people with cystic fibrosis - CFMATTERS Consortium

Einarsson, G., Flanagan, E., Lee, A., McGettigan, C., Smith, C., Gilpin, D., Elborn, J., Plant, B. J., Tunney, M. & on behalf of the CFMATTERS consortium, 06 Jun 2019, Journal of Cysric Fibrosis. Supplement 1 ed. European Cystic Fibrosis Society, Vol. Volume 18. p. S35 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
2018

Abstract: Factors affecting recruitment and attrition in randomised controlled trials of complementary and alternative medicine for pregnancy-related Issues

Close, C., Sinclair, M., McCullough, J., Liddle, D. & Hughes, C., 17 Apr 2018, RCN International Nursing Research Conference 2018: Book of Abstracts. RCN Publishing Company Limited, p. 46-47

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Automated quantification of retinal vessel morphometry in the UK biobank cohort

on behalf of the UK Biobank Eye and Vision Consortium, 12 Mar 2018, Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications (IPTA 2017). Institute of Electrical and Electronics Engineers Inc., 6 p. (International Conference on Image Processing Theory, Tools and Applications (IPTA): Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Conference Abstract: The safety of ante-natal reflexology and its impact on birth outcomes

Close, C., Sinclair, M., McCullough, J., Liddle, D. & Hughes, C., 04 Oct 2018, The safety of ante-natal reflexology and its impact on birth outcomes. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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6 Downloads (Pure)

Interpretable self-labeling semi-supervised classifier

Grau, I., Sengupta, D., Lorenzo, M. M. G. & Nowé, A., 19 Jul 2018, Proceedings of the 2nd Workshop on Explainable Artificial Intelligence: 27th International Joint Conference on Artificial Intelligence and the 23rd European Conference on Artificial Intelligence. Aha, D. W., Darrell, T., Doherty, P. & Magazzeni, D. (eds.). Stockholm, Sweden, p. 52-57

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Itch e3 ubiquitin ligase influences downstream receptor tyrosine kinase signalling in the oe33 cell line

Seeley, A., Cobbe, N., Turkington, R., Longley, D. & Evergren, E., 2018, Pharmacology 2017: British Pharmacological Society: Proceedings Annual Meeting.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Putting meat on bones: the development and installation of a wraparound-inspired early parenting intervention in community-based settings: A real-world theory-based evaluation

Hickey, G., Leckey, Y., Stokes, A., McGilloway, S., Bywater, T. & Donnelly, M., 19 Jul 2018, 1st UK Implementation Science Annual Research Conference: Proceedings.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The effect of increasing number of intravitreal vascular endothelial growth factor inhibitor injections on the rate of renal function decline in patients with diabetic macular oedema

Gallagher, P., Douglas, T., Silvestri, G., Little, J-A. & McKay, G., 09 Sep 2018, XXIII Biennial Meeting of the International Society for Eye Research: Abstract Book.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Using Record Linkage to Examine the Impact of Poor Mental Health on Breast Screening Uptake

Ross, E. & O'Reilly, D., 07 Jul 2018, Conference Proceedings for International Conference for Administrative Data Research 2018. 2 ed. Vol. 3. (International Journal of Population Data Science).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
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37 Downloads (Pure)
2017

Effectiveness of laser accelerated ultra high dose rate protons in DNA DSB damage induction under hypoxic conditions

Chaudhary, P., Gwynne, D., Doria, D., Romagnani, L., Maiorino, C., Padda, H., Alejo, A., Booth, N., Carroll, D., Kar, S., McKenna, P., Schettino, G., Borghesi, M. & Prise, K. M., 30 Nov 2017, 44th EPS Conference on Plasma Physics, EPS 2017: Proceedings. Bret, A., Fajardo, M., Westerhof, E., Melzer, A., Dromey, B. & Riconda, C. (eds.). European Physical Society (EPS), Vol. 41F. P1.217

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
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1 Citation (Scopus)
7 Downloads (Pure)

Genomic Variant Classifier Tool

Grau, I., Sengupta, D., Farid, D. M., Manderick, B., Nowe, A., Lorenzo, M. M. G., Daneels, D., Bonduelle, M., Croes, D. & Van Dooren, S., 20 Aug 2017, Proceedings of SAI Intelligent Systems Conference (IntelliSys) 2016. Springer, Cham, Vol. 15. p. 453-456 4 p. (Lecture Notes in Networks and Systems; vol. 15).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Itch, an E3 ubiquitin ligase, influences downstream receptor tyrosine kinase signalling in the colorectal cancer cell line, HCT116

Seeley, A., Longley, D. & Evergren, E., Feb 2017, 2017 Irish Association for Cancer Research: Proceedings.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

NanoStreams: Codesigned Microservers for Edge Analytics in Real Time

Georgakoudis, G., Gillan, C., Hassan, A., Minhas, U. I., Tzenakis, G., Spence, I., Vandierendonck, H., Woods, R., Nikolopoulos, D. S., Shyamsundar, M., Barber, P., Russell, M., Bilas, A., Kaloutsakis, S., Giefers, H., Staar, P., Bekas, C., Horlock, N., Faloon, R. & Pattison, C., 19 Jan 2017, Proceedings: 2016 International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation (SAMOS XVI) . Institute of Electrical and Electronics Engineers Inc., p. 180-187 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
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4 Citations (Scopus)
459 Downloads (Pure)

Retinal biomarker discovery for dementia in an elderly diabetic population

Fetit, A. E., Manivannan, S., McGrory, S., Ballerini, L., Doney, A., MacGillivray, T. J., Deary, I. J., Wardlaw, J. M., Doubal, F., McKay, G. J., McKenna, S. J. & Trucco, E., 10 Sep 2017, Fetal, Infant and Ophthalmic Medical Image Analysis - International Workshop, FIFI 2017 and 4th International Workshop, OMIA 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10554 LNCS. p. 150-158 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10554).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
283 Downloads (Pure)

Retinal microvascular changes in people with COPD compared to age-matched smokers without COPD

McKay, G., McCarter, R., Hogg, R., Bajaj, MPK., Burrage, DR., Ruickbie, S., Baker, E., Jones, PW. & Dodd, J., 19 May 2017, American Thoracic Society International Conference Abstracts. American Thoracic Society, p.A1012

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The Role of High Performance, Grid and Cloud Computing in High-Throughput Sequencing

Lightbody, G., Browne, F., Zheng, H., Haberland, V. & Blayney, J., 19 Jan 2017, 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM): Proceedings. 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
2 Citations (Scopus)
384 Downloads (Pure)

The unfolded protein response: a novel therapeutic target for poor prognostic BRAF mutant colorectal cancer

Van Schaeybroeck, S., Forsythe, N., Refaat, A., Javadi, A., Khawaja, H., Weir, J-A., Emam, H., Moore, W., Burkamp, F., Popovici, V., Jithesh, P., Isella, C., LaBonte Wilson, M., Mills, I. & Johnston, P., 2017, The unfolded protein response: a novel therapeutic target for poor prognostic BRAF mutant colorectal cancer. National Cancer Research Insitute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2016

ADAM17: a potential regulator of resistance to EGFR targeted therapies in RAS wild type colorectal cancer.

Weir, J-A., Gilliland, P., Fuchs, M-A., Williams, R., Murray, L., Johnston, P. & Van Schaeybroeck, S., Nov 2016, ADAM17: a potential regulator of resistance to EGFR targeted therapies in RAS wild type colorectal cancer.. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Can More High-Risk Cardiovascular Patients be Identified Using Novel Biomarkers? Extending the msm Package to Measure Reclassification.

Lamrock, F., Cairns, K., Conrads-Frank, A., Kee, F., Salomaa, V. & Siebert, U., 18 Aug 2016, IEEE 29th International Symposium on Computer-Based Medical Systems (CBMS) 20-24 June 2016. IEEE , p. 203-204 ( 29th International Symposium on Computer-Based Medical Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Impact on MPN Symptoms and Quality of Life of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia: Interim Analysis Results of Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial

Mesa, R. A., Hoffman, R., E Kosiorek, H., Prchal, J. T., Harrison, C. N., McMullin, M. F., Yacoub, A., Rambaldi, A., Berenzon, D., Vannucchi, A. M., Ewing, J. C., O'Connell, C. L., Kiladjian, J-J., Mead, A., Winton, E. F., Leibowitz, D. S., De Stefano, V., Arcasoy, M. O. & Kessler, C. M., 05 Dec 2016, Oral and Poster Abstracts for 58th Annual Meeting and Exposition for ASH. USA: American Society of Hematology, 4271

Research output: Chapter in Book/Report/Conference proceedingConference contribution

MErCuRIC1: A Phase Ia study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor crizotinib in patients with advanced solid tumours

Woodcock, V., Middleton, M., Rolfo, C., Elez, E., Van Schaeybroeck, S., Taieb, J., Houlden, J., Collins, L., Love, S., Roberts, C., Andre, T., Jones, R., Lawler, M., Di Nicolantonio, F., Grayson, M., Bardelli, A., Laurent=puig, P., McGregor, G., Maughan, T., Tabernero, J. & 2 others, Peeters, M. & Wilson, R., 11 Oct 2016, MErCuRIC1: A Phase Ia study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor crizotinib in patients with advanced solid tumours. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Modelling the Time Taken to Experience a Type 2 Diabetes Related Complication Using a Survival Tree in Order to Advise General Practitioners

Steele, C. J., Marshall, A. H., Kouvonen, A., Kee, F. & Sund, R., 18 Aug 2016, IEEE 29th International Symposium on Computer-Based Medical Systems, CBMS 2016: Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 271-272 2 p. (IEEE 29th International Symposium on Computer-Based Medical Systems (CBMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Upregulation of the MET transcript is consistently associated with invasion and tumor budding in colorectal cancer

Bradley, C., Dunne, P., McQuaid, S., Bingham, V., Lawler, M., Salto-Tellez, M., Johnston, P. & Van Schaeybroeck, S., 2016, Upregulation of the MET transcript is consistently associated with invasion and tumor budding in colorectal cancer. abstract 924 ed. Proceedings: AACR Annual Meeting 2016; April 16-20 New Orleans

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Using Simple PID Controllers to Prevent and Mitigate Faults in Scientific Workflows

Ferreira da Silva, R., Filgueira, R., Deelman, E., Pairo-Castineira, E., Overton, I. & Atkinson, M., 14 Nov 2016, Workflows in Support of Large-Scale Science: Proceedings of the 11th Workshop on Workflows in Support of Large-Scale Science co-located with The International Conference for High Performance Computing, Networking, Storage and Analysis (SC 2016). Vol. 1802. p. 15-24 (CEUR Workshop Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
5 Citations (Scopus)
99 Downloads (Pure)
2015

32 Activation of redox-sensitive inflammasomes underlies the biological phenotype of myelodysplastic syndromes

Coll, R., 01 Apr 2015, Leukemia Research.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A systematic review of the efficacy of atypical antipsychotics for post-traumatic stress disorder

Mulholland, C., Grant, R. & Lyons, T., 03 Jul 2015, Proceedings of Royal College of Psychiatrists International Congress 2015.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarker Discovery, High Performance and Cloud Computing: A Comprehensive Review

Blayney, J., Haberland, V., Lightbody, G. & Browne, F., 17 Dec 2015, Bioinformatics and Biomedicine (BIBM), 2015 IEEE International Conference. p. 1514-1519 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Challenges for the stratified medicine paradigm in treating chronic mental illness. Time to pay attention to what counts

Boeri, M., McMichael, A., Rolison, J., Kane, J., O'Neill, F. & Kee, F., Nov 2015, Poster presented at the 6th Annual UKCRC Public Health Research Centre of Excellence Conference; November 19, 2015. Edinburgh, UK.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Discrete Conditional Phase-type Model Utilising a Multiclass Support Vector Machine for the Prediction of Retinopathy of Prematurity

Rollins, R., Marshall, A. H., McLoone, E. & Chamney, S., Jun 2015, Computer-Based Medical Systems (CBMS), 2015 IEEE 28th International Symposium on. Institute of Electrical and Electronics Engineers (IEEE), p. 250-255 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

GeVaCT - Genomic Variant Classifier Tool

Daneels, D., Grau, I., Sengupta, D., Bonduelle, M., Farid, D. M., Croes, D., Nowé, A. & Santana-Varela, S., 01 Jul 2015, European Human Genetics Conference 2016. E-Supplement 1 ed. Barcelona, Spain: European Journal of Human Genetics, Vol. 24. p. 341 1 p. P16.06

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Modeling high-resolution SLO and OCT retinal imaging using backscattering of light from elementary sources

Vohnsen, B., Choi, S. S., Doble, N., Wells-Gray, E., Xu, H. & Stitt, A. W., 01 Jan 2015, Proceedings of Frontiers in Optics 2015, FIO 2015. OSA - The Optical Society

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Network signatures based on gene pair expression ratios improve classification and the analysis of muscle-invasive urothelial cancer

De Matos Simoes, R., Mitsiades, C., Williamson, K. & Emmert-Streib, F., 16 Dec 2015, Proceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015. Institute of Electrical and Electronics Engineers Inc., p. 1216-1223 8 p. 7359855

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The role of c-MET/HGF signaling as a critical mediator of an invasive and resistant phenotype in colorectal cancer

Bradley, C., Dunne, P., McArt, D., Arthur, K., McQuaid, S., Salto-Tellez, M., Johnston, P. & Van Schaeybroeck, S., 2015, The role of c-MET/HGF signaling as a critical mediator of an invasive and resistant phenotype in colorectal cancer. Proceedings: AACR Annual Meeting 2015; April 18-22, Philadelphia, Vol. Abstract 4018.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The role of micro-environment-derived ligands in resistance to EGFR monoclonal antibodies in KRAS wild type colorectal cancer

Weir, J-A., Redmond, K., Bradley, C. & Van Schaeybroeck, S., Nov 2015, The role of micro-environment-derived ligands in resistance to EGFR monoclonal antibodies in KRAS wild type colorectal cancer. National Cancer Research Institute, Vol. A87.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The role of Oncogenic BRAF in regulating growth factor/cytokine shedding and drug resistance in colorectal cancer

Forsythe, N., Celtikci, B., Johnston, P. & Van Schaeybroeck, S., Nov 2015, The role of Oncogenic BRAF in regulating growth factor/cytokine shedding and drug resistance in colorectal cancer. National Cancer Research Institute, Vol. A221.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014

An unusual finding in the dissection room: An unusual finding in the dissection room

Quinn, J. & Foy, C., 2014, Institute of Anatomical Sciences.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A smartphone based ophthalmoscope

Giardini, M. E., Livingstone, I. A. T., Jordan, S., Bolster, N. M., Peto, T., Burton, M. & Bastawrous, A., 06 Nov 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , Vol. 2014. p. 2177-80 4 p. (IEEE Engineering in Medicine and Biology Society. Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

29 Citations (Scopus)

EpHA2 is an essential driver of invasion and a novel target in KRAS mutant colorectal cancer

Dunne, P., McArt, D., Blayney, J., Dasgupta, S., Salto-Tellez, M., Johnston, P. & Van Schaeybroeck, S., 2014, EpHA2 is an essential driver of invasion and a novel target in KRAS mutant colorectal cancer . Proceedings: AACR Annual Meeting 2014; April 5-9, San Diego, Vol. Abstract 2079.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

EphA2 is an essential driver of invasion downstream of the KRAS signalling cascade in colorectal cancer.

Dunne, P., McArt, D., Blayney, J., Dasgupta, S., Salto-Tellez, M., Johnston, P. & Van Schaeybroeck, S., Nov 2014, EphA2 is an essential driver of invasion downstream of the KRAS signalling cascade in colorectal cancer.. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

FCHo2 regulates protein assembly and efficiency of clathrin-mediated endocytosis

Evergren, E. & McMahon, H. T., 2014, 2014 American Society for Cell Biology Conference: Proceedings.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Integrative analysis of chemo-transcriptomic profiles for drug-feature specific gene expression signatures

Kim, C. S., Wen, Q. & Zhang, S-D., Nov 2014, Proceedings for 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). Institute of Electrical and Electronics Engineers (IEEE), p. 113-118 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Is my patient responding to treatment? The seldom asked question in personalized medicine research

McMichael, A., Kee, F., Rolison, J., Boeri, M., Kane, J. & O'Neill, F., Oct 2014, Society of Medical Decision Making.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Progress in Laser-Driven Ion Acceleration towards Applications in Radiotherapy

McKenna, P., Borghesi, M., Neely, D., Najmudin, Z., Zepf, M. & Prise, K., Jun 2014, CLEO: Applications and Technology.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Regulatory T cells promote CNS myelin regeneration in vivo

Dombrowski, Y., 2014, Journal of Neuroimmunology-Proceedings of the XII International Congress of Neuroimmunology. Racke, M. (ed.). Vol. 275, issues 1-2.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

RMA with quantile normalization mixes biological signals between different sample groups in microarray data analysis

Kim, C. S., Hwang, S. & Zhang, S-D., Nov 2014, 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). Institute of Electrical and Electronics Engineers (IEEE), p. 139-143 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Targeting of calcium/calmodulin-dependent protein kinase II delta and gamma isoforms inhibits growth factor-induced retinal angiogenesis in vitro

Ashraf, S., McCauley, H., Stitt, A. W., McGeown, G. J. & Curtis, T. M., Apr 2014, Investigative Opthalmology and Visual Science (Journal - Meeting abstract). Vol. 55 (13). p. 3019 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution