School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Meeting abstract
2016

Cigarettes, e-cigarettes and Pseudomonas aeruginosa: Interactions in the CF lung?

McGown, K-A., Bengoechea, J., Dumigan, A., Elborn, J. S., Tunney, M. M. & Gilpin, D., Jun 2016, In : Journal of Cystic Fibrosis. 15, Supplement 1, p. S65 1 p.

Research output: Contribution to journalMeeting abstract

Clinical isolates of Mycobacterium avium drive collagenolytic and elastolytic activity in mononuclear cells

McFetridge, S., McMullan, R. & O'Kane, C., 01 Dec 2016, In : Thorax. 71, Supplament 3, p. 1-1 s 38.

Research output: Contribution to journalMeeting abstract

Mycobacterium avium
Matrix Metalloproteinases
Lung
Lung Diseases
Monocytes
63 Downloads (Pure)

Development of a primary care-based intervention to improve appropriate polypharmacy in older people using a systematic and theory-based method.

Cadogan, C. A., Ryan, C., Francis, J. J., Gormley, G., Passmore, A., Kerse, N. & Hughes, C., 16 Nov 2016, In : International Journal of Pharmacy Practice. 24, p. 16-17

Research output: Contribution to journalMeeting abstract

Open Access
File
Polypharmacy
Primary Health Care
General Practitioners
Testing
Taxonomies
14 Citations (Scopus)

Does Precision Teaching enhance dermatology diagnostic skills in medical students?

McGrath, C., McCourt, C., Gormley, G., Dillenburger, K., Dounavi, K. & Corry, A., 04 Jul 2016, In : British Journal of Dermatology. 175, Supplement 1, p. 199-200 2 p.

Research output: Contribution to journalMeeting abstract

Does the choice of hormone therapy affect medium-term outcomes following radical external beam radiotherapy for localized prostate cancer?

Lyons, C., Blayney, J., Mitchell, D. M., Harney, J. A., McAleese, J., Shum, L., Stewart, D. P., Jain, S. & O'Sullivan, J., 2016, In : Journal of Clinical Oncology. 34, 15 supplement, p. e16588-e16588 1 p., 16588.

Research output: Contribution to journalMeeting abstract

Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R., Butler, M. S., Robertson, A. A. B., O'Neill, L. A. J., Murphy, A. J., Cooper, M. A. & Febbraio, M. A., 19 Aug 2016, In : European Journal of Immunology. 46, p. 444 1 p.

Research output: Contribution to journalMeeting abstract

Inflammasomes
Type 2 Diabetes Mellitus
Interleukin-1beta
Inflammation
Insulin-Secreting Cells

Expanding access to evidence-based medicine to physicians and medical students in resource-poor settings to improve medical education.

Valtis, Y. K., R, W., Wachter, K., Chande, R., Mashili, F., Kisenge, R., Walker, T., Kennedy, N., Maling, S., Bhandari, S., Teichman, M. & Barron, E., May 2016, In : Annals of Global Health . 82, p. 602 1 p.

Research output: Contribution to journalMeeting abstract

Exploring the timing of Hypertonic Saline (HTS) and Airways Clearance Techniques (ACT) in Cystic Fibrosis (CF): a cross over study

Bradley, JM., O'Neill, K., Moran, F., Bradbury, I., Downey, DG., Rendall, JS., Tunney, MM. & Elborn, JS., 01 Dec 2016, In : Thorax. p. A134-A135 2 p.

Research output: Contribution to journalMeeting abstract

Fractional Exhaled Nitric Oxide (FeNO) Suppression to identify Non-adherence in Difficult Asthma

Hetherington, K. J., Costello, R. W. & Heaney, L. G., 01 Dec 2016, In : Thorax. 71, Supp 3

Research output: Contribution to journalMeeting abstract

Adrenal Cortex Hormones
Nitric Oxide
Asthma
Biomarkers
Steroids

How specific are fluorogenic substrates designed to analyse active protease biomarkers of respiratory disease?

Robb, C., Ferguson, T., Moffitt, K., Downey, D., McCafferty, D., Ribeiro, D., Martin, L. & Walker, B., Dec 2016, In : Thorax. 71, Suppl 3, p. A79-A80 2 p.

Research output: Contribution to journalMeeting abstract

Fluorescent Dyes
Peptide Hydrolases
Biomarkers
Pancreatic Elastase
Trypsin

Identification of potentially pathogenic variants in candidate breast and ovarian cancer susceptibility genes in BRCAX patients

Savage, A. L., Chenevix-Trench, G., Jun Li, J., McDade, S. S., Morrison, P. J., McIntosh, S. A., Harkin, D. P. & Savage, K. I., Jun 2016, In : Current Oncology. 23, 3, p. e308 1 p., P089.

Research output: Contribution to journalMeeting abstract

Neoplasm Genes
Ovarian Neoplasms
Breast Neoplasms
Mutation
Genes
25 Citations (Scopus)
123 Downloads (Pure)

"I Don't Need a Piece of Paper with Scores to Tell Me that Somebody's in Pain and I Need to Do Something about it". Nurses' and Healthcare Assistants' Perspectives on and Use of Pain Assessment Tools with People Dying with Advanced Dementia

De Witt Jansen, B., Brazil, K., Passmore, A., Buchanan, H., Maxwell, D., McIlfatrick, S., Morgan, S., Watson, M. & Parsons, C., Jun 2016, In : Palliative Medicine. 30, 6, p. NP45-NP46 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
File

Loss of Function Cohesin Complex Gene Mutations Create Neomorphic Cell States Advantageous to Oncogeneisis

Smith, J., Savage, K., Thompson, A. & Mills, K., 22 Oct 2016, In : Blood. 128, p. 1564-1565 2 p.

Research output: Contribution to journalMeeting abstract

MErCuRIC1: A phase 1a study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor crizotinib in patients with advanced solid tumours

Wilson, R., Middleton, M., Houlden, J., Van Schaeybroeck, S., Rolfo, C., Elez, E., Taieb, J., Andre, T., Bardelli, A., Laurent=puig, P., Tabernero, J., Peeters, M., Maughan, T., Roberts, C., Love, S., Lawler, M., Salto-Tellez, M., Grayson, M., Popovici, V. & Di Nicolantonio, F., 08 Oct 2016, In : Annals of Oncology (2016) 27 (6): 149-206. .

Research output: Contribution to journalMeeting abstract

Maximum Tolerated Dose
Neoplasms
Fatigue
Hypoalbuminemia
crizotinib
20 Downloads (Pure)
Open Access
File

Novel Genetic Determinants of Diabetic Kidney Disease

Todd, J. N., Salem, R., Sandholm, N., Valo, E. A., Hiraki, L. T., Di Liao, C., Pezzolesi, M. G., Smiles, A., Onengut-Gumuscu, S., Chen, W. M., McGurnaghan, S., McKeigue, P., McKnight, A. J., Maxwell, A. P., Colhoun, H. M., Krolewski, A. S., Paterson, A. D., Rich, S. S., Hirschhorn, J. N. & Florez, J. C., Jun 2016, In : Diabetes. 65, S1, p. A100 1 p.

Research output: Contribution to journalMeeting abstract

Diabetic Nephropathies
Chronic Kidney Failure
Single Nucleotide Polymorphism
Hereditary Nephritis
Focal Segmental Glomerulosclerosis

Oncostatin M is a novel mediator of human pulmonary endothelial chemokine and protease activity in the lung in ARDS

Fitzgerald, M., McAuley, D. & O'Kane, C., 01 Dec 2016, In : Thorax. 71, p. A47 S81.

Research output: Contribution to journalMeeting abstract

Overview of an Advance Care Planning (ACP) Model for Care Home Residents Living with Dementia

Brazil, K., Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Froggatt, K., Passmore, P. & Cardwell, C., Dec 2016, In : Journal of Pain and Symptom Management. 52, 6, p. e126 1 p., P231.

Research output: Contribution to journalMeeting abstract

Preclinical radiotherapy technology, dosimetry and treatment planning

Butterworth, K., Ghita, M., McGarry, C. K., Jain, S., Hanna, G. G., O'Sullivan, J. M., Hounsell, A. R. & Prise, K. M., Apr 2016, In : Radiotherapy and Oncology. 119, Supplement 1 , p. S238-S239 2 p.

Research output: Contribution to journalMeeting abstract

302 Downloads (Pure)
Open Access
File

Protocol: Quality of Life, Decision Making, Costs and Impact on Carers in People Managed without Dialysis - The PACKS Study

Noble, H., Maxwell, P., Yaqoob, M., Normand, C., Brazil, K., Burns, A. & Roderick, P., Jun 2016, In : Palliative Medicine. 30, 6, p. NP67 41 p., MTE6.

Research output: Contribution to journalMeeting abstract

Caregivers
Dialysis
Decision Making
Quality of Life
Costs and Cost Analysis
Feasibility Studies
Prostate
Prostatic Neoplasms
Radiotherapy
Seminal Vesicles

Susceptibility of Staphylococcus aureus isolates from patients with and without cystic fibrosis to ceftobiprole

Gilpin, D., Carson, G., Lee, A., McGrath, S., Elborn, J. S. & Tunney, M. M., Jun 2016, In : Journal of Cystic Fibrosis. 15, S1, p. S83-S84 2 p., 129.

Research output: Contribution to journalMeeting abstract

Targeting siglecs to reduce protease-mediated destruction in tuberculosis

Beynon, W., McMullan, R. & O'Kane, C., 15 Nov 2016, In : Thorax. 71, Supplement 48 , p. A29-A30

Research output: Contribution to journalMeeting abstract

The development of a core outcome set for medicines management interventions in people with dementia

McGrattan, M., Barry, H. E., Ryan, C., Cooper, J. A., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Sep 2016, In : International Journal of Pharmacy Practice. 24, S3, p. 74-75 2 p., 0110.

Research output: Contribution to journalMeeting abstract

The E3 ligase HUWE1 is a potential therapeutic target in Multiple Myeloma

Crawford, L. & Irvine, A., 01 Dec 2016, In : Blood. 128, 22, 240.

Research output: Contribution to journalMeeting abstract

The Utility of Post-Chemotherapy PET Scans in Resectable Oesophageal Adenocarcinoma

Turkington, R., McManus, D., David, C., Napier, E., Kennedy, A., Carey, D., Clements, B., Harrison, C., Purcell, C., Eatock, M. & Kennedy, R., 22 Sep 2016, In : British Journal of Surgery.

Research output: Contribution to journalMeeting abstract

16 Citations (Scopus)
104 Downloads (Pure)

Transitions experienced by carers on the living-dying journey of a relative with dementia.

Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Froggatt, K., Passmore, A. & Brazil, K., Jun 2016, In : Palliative Medicine. 30, 6, p. NP171 P201.

Research output: Contribution to journalMeeting abstract

Open Access
File

Trypsin-like Protease Activity in Adult CF Sputum Sol Inversely Correlates With Lung Function & Patient Survival

Reihill, J. A., Moffitt, K. L., Jones, A. M., Elborn, J. S. & Martin, S. L., Oct 2016, In : Pediatric Pulmonology. 51, S45, p. 261 1 p.

Research output: Contribution to journalMeeting abstract

31 Citations (Scopus)

Trypsin-like protease activity predicts disease severity and patient mortality in adults with cystic fibrosis

Reihill, J., Moffitt, K., Jones, A., Elborn, J. & Martin, L., 15 Dec 2016, In : Thorax. 71, Suppl 3, p. A133

Research output: Contribution to journalMeeting abstract

Cystic Fibrosis
Trypsin
Peptide Hydrolases
Mortality
Leukocyte Elastase

UK consensus project on quality in palliative day services: developing a quality indicator set using the RAND/UCLA appropriateness method

McCorry, N., Dempster, M., O'Connor, S., Armour, K., Coast, J., Cohen, J., Donnelly, M., Finucane, A., Fyvie, J., Jones, L., Kernohan, G., Leemans, K., Oxenham, D. & Perkins, P., 01 Sep 2016, In : BMJ Supportive and Palliative Care. 6, 3

Research output: Contribution to journalMeeting abstract

Risk Adjustment
Benchmarking
Quality Improvement
Palliative Care
Primary Health Care

Vorinostat Does Not Improve Outcome in Patients with Acute Myeloid Leukemia and High Risk Myelodysplasia Treated with Azacitidine: Results of the UK Trials Acceleration Programme Ravva Trial

Craddock, C., Houlton, A. E., Ferguson, P., Raghavan, M., Fox, S., Dudley, L., Quek, L. S., Cavenagh, J. D., Dennis, M., Wheatley, K., Vyas, P., McMullin, M. F., Pillai, S. P., Kelly, R., Siddique, S., Wheatley, K. & Vyas, P., 30 Nov 2016, In : Blood. 128, 22, p. 1065

Research output: Contribution to journalMeeting abstract

1 Downloads (Pure)
Open Access
File
Longitudinal Studies
Prospective Studies
Psychology
2015

100 Macrolide resistance is common among members of the CF airway microbiota.

Sherrard, L., Alawsi, F., McGrath, S., McIlreavey, L., Elborn, J. & Tunney, M., Jun 2015, In : Journal of Cystic Fibrosis.

Research output: Contribution to journalMeeting abstract

1032 Obesity and central obesity in older adults and cancer risk: Meta-analysis of individual participant data from prospective cohort studies of the CHANCES consortium

Freisling, H., Arnold, M., Soerjomataram, I., O'Doherty, M., Ordonez Mena, J., Bamia, C., Kampman, E., Wilsgaard, T. & Jenab, M., Sep 2015, In : European Journal of Cancer. 51, Supplement 3, p. S155-S156 2 p.

Research output: Contribution to journalMeeting abstract

72 Potential for airborne bacterial contamination in an outpatient respiratory clinic

McElderry, J., O'Neill, K., Tunney, M. M., Downey, D. G., Rendall, J. C., Moore, J. E., Elborn, J. S. & Gilpin, D. F., Jun 2015, In : Journal of Cystic Fibrosis. 14, Supplement 1, p. S75 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
Ambulatory Care Facilities

93 Production of virulence factors by Prevotella isolates belonging to the cystic fibrosis (CF) respiratory microbiota

Sherrard, L. J., Matier, T. B., Nixon, K. A., McGrath, S., McIlreavey, L., Hatch, J., Wolfgang, M. C., Muhlebach, M. S., Gilpin, D. F., Elborn, J. S. & Tunney, M. M., Jun 2015, In : Journal of Cystic Fibrosis. 14, Supplement 1, p. S81 1 p.

Research output: Contribution to journalMeeting abstract

Open Access

Abdominal adiposity and periodontitis: a Mendelian randomisation study

Linden, G., Winning, L., Lundy, F., Kee, F. & Patterson, C., 2015, In : Journal of Dental Research.

Research output: Contribution to journalMeeting abstract

A case of an unusual palatal lymphoma

Willis, A., 2015, In : International Journal of Oral and Maxillofacial Surgery. S1 , 44

Research output: Contribution to journalMeeting abstract

104 Downloads (Pure)

An evaluation of a free lunch initiative in a Northern Irish workplace

Schliemann, D., McKinley, M. & Woodside, J., 11 Sep 2015, In : Proceedings of the Nutrition Society. 74, OCE4, E237.

Research output: Contribution to journalMeeting abstract

Open Access
File

A novel inhibitor of channel activating proteases: Putting the CAP on ENaC

Reihill, J. A., Walker, B., Harvey, B., Stutts, J., Elborn, J. S. & Martin, S. L., Oct 2015, In : Pediatric Pulmonology. 50, Suppl 41, p. 229 1 p.

Research output: Contribution to journalMeeting abstract

Peptide Hydrolases
Mucociliary Clearance
Furin
Epithelial Sodium Channels
Epithelial Cells

A Novel Inhibitor of Channel Activating Proteases: Putting the Cap on ENAC

Reihill, J. A., Walker, B., Harvey, B., Stutts, J. & Elborn, J., Oct 2015, In : Pediatric Pulmonology. 50, S41, p. S229 1 p.

Research output: Contribution to journalMeeting abstract

Asthma and nasal allergies associate with reduced pancreatic cancer risk

Gomez-Rubio, P., Zock, J-P., Sharp, L., Hidalgo, M., Carrato, A., Ilzarbe, L., michalski, C., Molero, X., Farré, A., Perea, J., Greenhalf, W., O'Rorke, M., Tardón, A., Barberà, V., Crnogorac-Jurcevic, T., Domínguez-Muñoz, E., Muñoz-Bellvís, L., Löhr, M., Scarpa, A., Real, F. X. & 1 others, Malats, N., Jun 2015, In : Pancreatology. 15, 3, p. S124–S125 2 p., 1082.

Research output: Contribution to journalMeeting abstract

Biodentine™ reduces TNF-α induced TRPA1 expression in odontoblasts

El Karim, I., About, I., Curtis, T., Linden, G. & Lundy, F., 2015, In : Journal of Dental Research.

Research output: Contribution to journalMeeting abstract