School of Medicine, Dentistry and Biomedical Sciences &ndash; Research Output

2019

1 Citation (Scopus)

123I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults

Roberts, G., Lloyd, J. J., Petrides, G. S., Donaghy, P., Kane, J., Durcan, R., Lawley, S., Howe, K., Sims, A., Taylor, J-P., O'Brien, J. T. & Thomas, A. J., 21 Mar 2019, In : Annals of Nuclear Medicine.

Research output: Contribution to journal › Article

Corpus Striatum

Lewy Body Disease

Nortropanes

Software

2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane

4 Citations (Scopus)

123I-MIBG scintigraphy utility and cut-off value in a clinically representative dementia cohort

Kane, J. P. M., Roberts, G., Petrides, G. S., Lloyd, J. J., O'Brien, J. T. & Thomas, A. J., 26 Jan 2019, In : Parkinsonism and Related Disorders.

Research output: Contribution to journal › Article

3-Iodobenzylguanidine

Radionuclide Imaging

Dementia

Mediastinum

Lewy Body Disease

1 Citation (Scopus)

2-hydroxylation of Acinetobacter baumannii lipid A contributes to virulence

Bartholomew, T. L., Kidd, T. J., Sá Pessoa, J., Conde Álvarez, R. & Bengoechea, J. A., 25 Mar 2019, In : Infection and Immunity.

Research output: Contribution to journal › Article

Open Access

File

Acinetobacter baumannii

Lipid A

Hydroxylation

Virulence

Interleukin-10

A Case of Transient Diplopia and Ophthalmoplegia Following Dental Anesthesia

Peto, T., Seres, L., Petho, G. & Peto, Z., 14 Aug 2019, In : Nigerian Journal of Clinical Practice.

Research output: Contribution to journal › Article

Open Access

File

Dental Anesthesia

Ophthalmoplegia

Diplopia

Dentists

Patient Care

A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells

Winning, L., El Karim, I. A. & Lundy, F. T., 01 Aug 2019, In : Stem Cells and Development. 28, 15, p. 1050-1058 9 p.

Research output: Contribution to journal › Article

Dental Pulp

Mesenchymal Stromal Cells

Deciduous Tooth

Tooth

Periodontal Ligament

A Comparison of Inpatient and Outpatient-Based Chemotherapy Regimens for the Treatment of Acute Myeloid Leukaemia In The Elderly

Daly, A. B., Cuthbert, R., Finnegan, D., Arnold, C., Craddock, C. & McMullin, M. F., Jan 2019, In : The Ulster Medical Journal. 88, 1, p. 25-29 5 p.

Research output: Contribution to journal › Article

Open Access

File

Acute Myeloid Leukemia

Inpatients

Outpatients

Drug Therapy

Survival

1 Citation (Scopus)

A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma

Wong, R. K. Y., MacMahon, M., Woodside, J. V. & Simpson, D. A., 03 Jun 2019, In : BMC Genomics. 20, 12 p., 446.

Research output: Contribution to journal › Article

Open Access

File

RNA Sequence Analysis

MicroRNAs

RNA

Libraries

Biomarkers

1 Citation (Scopus)

A comparison of visual and semiquantitative analysis methods for planar cardiac 123I-MIBG scintigraphy in dementia with Lewy bodies

Roberts, G., Kane, J., Lloyd, J. J., Petrides, G. S., Howe, K., O'Brien, J. T. & Thomas, A. J., 02 May 2019, In : Nuclear Medicine Communications.

Research output: Contribution to journal › Article

A Core Outcome Set for Critical Care Ventilation Trials

Blackwood, B., Ringrow, S., Clarke, M., Marshall, J. C., Connolly, B., Rose, L. & McAuley, D. F., 25 Jul 2019, In : Critical Care Medicine.

Research output: Contribution to journal › Article

Open Access

File

Delphi Technique

Ventilation

Clinical Trials

Critical Care

Artificial Respiration

Activated P13Kd disrupts germinal centre GC T(fh)/GC B cell cross talk and B cell antibody coding

Rea, I. M., 08 Oct 2019, In : Cellular and Molecular Immunology. p. 1-3

Research output: Contribution to journal › Article

Germinal Center

B-Lymphocytes

Antibodies

Lymphopenia

Vaccination

1 Citation (Scopus)

Acute and chronic hypoxia differentially predispose lungs for metastases

Reiterer, M., Colaço, R., Emrouznejad, P., Jensen, A., Rundqvist, H., Johnson, R. S. & Branco, C., 15 Jul 2019, In : Scientific Reports. 9, 15 p., 10246.

Research output: Contribution to journal › Article

Open Access

File

Endothelial cells

Neoplasm Metastasis

Lung

Tumors

Endothelial Cells

Adaptive radiotherapy for head and neck cancer reduces the requirement for rescans during treatment due to spinal cord dose

Belshaw, L., Agnew, C. E., Irvine, D. M., Rooney, K. & McGarry, C., 01 Nov 2019, In : Radiation Oncology.

Research output: Contribution to journal › Article

Open Access

File

Cone-Beam Computed Tomography

Head and Neck Neoplasms

Spinal Cord

Radiotherapy

Workload

Adjustment strategies amongst black African and black Caribbean men following treatment for prostate cancer: findings from the Life After Prostate Cancer Diagnosis (LAPCD) study

Wagland, R., Nayoan, J., Matheson, L., Rivas, C., Brett, J., Collaço, N., Alexis, O., Gavin, A., Glaser, A. W. & Watson, E., 01 Oct 2019, (Accepted) In : European Journal of Cancer Care.

Research output: Contribution to journal › Article

Social Adjustment

Prostatic Neoplasms

Therapeutics

Masculinity

Patient-Centered Care

A feasibility study of ‘The StepSmart Challenge’ to promote physical activity in adolescents

Corepal, R., Best, P., O'Neill, R., Kee, F., Badham, J., Dunne, L., Miller, S., Connolly, P., Cupples, M., van Sluijs, E. M. F., Tully, M. & Hunter, R. F., 17 Nov 2019, In : Pilot and Feasibility Studies. 5, 15 p., 132.

Research output: Contribution to journal › Article

Open Access

File

Feasibility Studies

Exercise

Reward

Social Support

Northern Ireland

2 Citations (Scopus)

A Four-Group Urine Risk Classifier for Predicting Outcome in Prostate Cancer Patients

Movember GAP1 Urine Biomarker Consortium, 20 May 2019, In : BJU International.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Urine

Prostate

RNA

Biopsy

2 Citations (Scopus)

A framework for characterising and evaluating the effectiveness of environmental modelling

Hamilton, S. H., Fu, B., Guillaume, J. H. A., Badham, J., Elsawah, S., Gober, P., Hunt, R. J., Iwanaga, T., Jakeman, A. J., Ames, D. P., Curtis, A., Hill, M. C., Pierce, S. A. & Zare, F., 01 Aug 2019, In : Environmental Modelling and Software. 118, p. 83-98 16 p.

Research output: Contribution to journal › Article

environmental modeling

accessibility

modeling

evaluation

A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans

Mohamed, Y. F., Scott, N. E., Molinaro, A., Creuzenet, C., Ortega, X., Lertmemongkolchai, G., Tunney, M. M., Green, H., Jones, A. M., DeShazer, D., Currie, B. J., Foster, L. J., Ingram, R., De Castro, C. & Valvano, M. A., 26 Jul 2019, In : The Journal of biological chemistry.

Research output: Contribution to journal › Article

Open Access

File

Burkholderia

Glycosylation

Machinery

Polysaccharides

Burkholderia cenocepacia

9 Citations (Scopus)

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Lux, F., Tran, V. L., Thomas, E., Dufort, S., Rossetti, F., Martini, M., Truillet, C., Doussineau, T., Bort, G., Denat, F., Boschetti, F., Angelovski, G., Detappe, A., Crémillieux, Y., Mignet, N., Doan, B-T., Larrat, B., Meriaux, S., Barbier, E., Roux, S. & 28 othersFries, P., Müller, A., Abadjian, M-C., Anderson, C., Canet-Soulas, E., Bouziotis, P., Barberi-Heyob, M., Frochot, C., Verry, C., Balosso, J., Evans, M., Sidi-Boumedine, J., Janier, M., Butterworth, K., McMahon, S., Prise, K., Aloy, M-T., Ardail, D., Rodriguez-Lafrasse, C., Porcel, E., Lacombe, S., Berbeco, R., Allouch, A., Perfettini, J-L., Chargari, C., Deutsch, E., Le Duc, G. & Tillement, O., 01 Jan 2019, In : British Journal of Radiology. 92, 1093, 19 p., 20180365.

Research output: Contribution to journal › Article

Open Access

File

Clinical Medicine

Gadolinium

Nanoparticles

Radiation-Sensitizing Agents

Siloxanes

A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., 13 Nov 2019, In : Stem Cells.

Research output: Contribution to journal › Article

Histone Deacetylases

Blood Vessels

Regeneration

Phosphorylation

Amino Acids

Airway surface liquid has innate antiviral activity that is reduced in cystic fibrosis

Berkebile, A. R., Bartlett, J. A., Alaiwa, M. A., Varga, S. M., Power, U. & McCray, P. B., 26 Jun 2019, In : American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journal › Article

Open Access

File

Cystic Fibrosis

Antiviral Agents

Viruses

Liquids

Fibrosis

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications

Hill, M., Twigg, M., Sheridan, E. A., Hardy, J. G., Elborn, J. S., Taggart, C. C., Scott, C. J. & Migaud, M. E., 02 Aug 2019, In : Pharmaceutics. 11, 8, 12 p., 379.

Research output: Contribution to journal › Article

Open Access

File

Tobramycin

Chitosan

Mucus

Drug Delivery Systems

Cystic Fibrosis

Alterations in retinal arteriolar microvascular structure associates with higher treatment burden in patients with diabetic macular edema: results from a 12-month prospective clinical trial

Blindbæk, S. L., Peto, T. & Grauslund, J., 25 Oct 2019, In : Acta Ophthalmologica.

Research output: Contribution to journal › Article

Macular Edema

Clinical Trials

Light Coagulation

Therapeutics

Lasers

2 Citations (Scopus)

Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability

Liberante, F. G., Lappin, K., Barros, E. M., Vohhodina, J., Grebien, F., Savage, K. I. & Mills, K. I., 25 Feb 2019, In : Scientific Reports. 9, 13 p., 2678.

Research output: Contribution to journal › Article

Open Access

File

Amino Acyl-tRNA Synthetases

Azaguanine

Myelodysplastic Syndromes

Mutation

RNA Splicing

A Machine Learning Platform to Optimize the Translation of Personalized Network Models to the Clinic

Salvucci, M., Rahman, A., Resler, A. J., Udupi, G. M., McNamara, D. A., Kay, E. W., Laurent-Puig, P., Longley, D. B., Johnston, P. G., Lawler, M., Wilson, R., Salto-Tellez, M., Van Schaeybroeck, S., Rafferty, M., Gallagher, W. M., Rehm, M. & Prehn, J. H. M., 17 Apr 2019, In : JCO Clinical Cancer Informatics. 17 p.

Research output: Contribution to journal › Article

Open Access

File

Protein Array Analysis

Colorectal Neoplasms

Proteins

Immunohistochemistry

Workflow

1 Citation (Scopus)

A magnetic self-contained thermochromic system with convenient temperature range

Billeci, F., Gunaratne, H. Q., D'Anna, F., Morgan, G., Seddon, K. R. & Plechkova, N., 2019, In : Green Chemistry. 21, 6, p. 1412-1416 5 p.

Research output: Contribution to journal › Article

Ionic Liquids

Ionic liquids

volatile substance

Cobalt

Polymer films

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A. E., Doney, A. S., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 05 Mar 2019, In : Scientific Reports. 9, 10 p., 3591.

Research output: Contribution to journal › Article

Open Access

File

Type 2 Diabetes Mellitus

Single Nucleotide Polymorphism

Biomarkers

Blood Pressure

HDL Lipoproteins

1 Citation (Scopus)

Analysis of KRAS, NRAS, BRAF, PIK3CA and TP53 mutations in a large prospective series of locally advanced rectal cancer patients

Sclafani, F., Hulkki Wilson, S., Cunningham, D., Gonzalez De Castro, D., Kalaitzaki, E., Begum, R., Wotherspoon, A., Capdevila, J., Glimelius, B., Roselló, S., Thomas, J., Tait, D., Brown, G., Oates, J. & Chau, I., 14 Jun 2019, In : International Journal of Cancer.

Research output: Contribution to journal › Article

Rectal Neoplasms

Mutation

Disease-Free Survival

Neoplasms

Neoplasm Genes

An Analysis of Medical Students’ Attitude and Motivation in Pursuing an Intercalated MSc in Clinical Anatomy

Abdel Meguid, E. & Allen, W. E., 12 Feb 2019, In : Medical Science Educator.

Research output: Contribution to journal › Article

Open Access

File

Medical Students

Motivation

Anatomy

Students

Research

Heron, N., Nolan, R. & Usher, R., 13 Nov 2019, (Accepted) In : Journal of Science and Cycling .

Research output: Contribution to journal › Article

athlete

professional sports

road

cause

An RCT of atraumatic restorative treatment for older adults: 5 year results

Da Mata, C., McKenna, G., Anwigi, L., Hayes, M., Woods, N., O'Mahony, D. & Allen, PF., 09 Mar 2019, In : Journal of Dentistry. 5 p.

Research output: Contribution to journal › Article

Survival

Survival Rate

Dental Care

Therapeutics

Dentists

Antidepressant medication use among working age first-generation migrants resident in Finland : an administrative data linkage study

Bosqui, T., Väänänen, A., Buscariolli, A., Koskinen, A., O'Reilly, D., Airila, A. & Kouvonen, A., 16 Oct 2019, In : International Journal of Equity in Health. 18, 1, p. 157

Research output: Contribution to journal › Article

Open Access

File

Information Storage and Retrieval

Finland

Antidepressive Agents

Prescriptions

Mental Health

A nurse-led, preventive, psychological intervention to reduce PTSD symptom severity in critically ill patients: the POPPI feasibility study and cluster RCT

Mouncey, P. R., Wade, D. M., Richards-Belle, A., Sadique, Z., Wulff, J., Grieve, R., Emerson, L., Brewin, C. R., Harvey, S., Howell, D., Hudson, N., Khan, I., Mythen, M., Smyth, D., Weinman, J., Welch, J. J., Harrison, D. & Rowan, K. M., 01 Aug 2019, In : Health Services and Delivery Research. 7, 30, 206 p.

Research output: Contribution to journal › Article

Open Access

File

Feasibility Studies

Post-Traumatic Stress Disorders

Critical Illness

Randomized Controlled Trials

Nurses

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 06 Sep 2019, In : Molecular Psychiatry. 16 p.

Research output: Contribution to journal › Article

Open Access

File

Schizophrenia

Disease Resistance

Penetrance

Genomics

Psychiatry

Application of 1H-NMR Metabolomics for the Discovery of Blood Plasma Biomarkers of a Mediterranean Diet

Macias, S., Kirma, J., Yilmaz, A., Moore, S. E., McKinley, M. C., McKeown, P. P., Woodside, J. V., Graham, S. F. & Green, B. D., 27 Sep 2019, In : Metabolites. 9, 10, 14 p., 201.

Research output: Contribution to journal › Article

Open Access

File

Mediterranean Diet

Metabolomics

Biomarkers

Nutrition

Blood

7 Citations (Scopus)

Application of high-sensitivity troponin in suspected myocardial infarction

Neumann, J. T., Twerenbold, R., Ojeda, F., Sörensen, N. A., Chapman, A. R., Shah, A. S. V., Anand, A., Boeddinghaus, J., Nestelberger, T., Badertscher, P., Mokhtari, A., Pickering, J. W., Troughton, R. W., Greenslade, J., Parsonage, W., Mueller-Hennessen, M., Gori, T., Jernberg, T., Morris, N., Liebetrau, C. & 34 othersHamm, C., Katus, H. A., Münzel, T., Landmesser, U., Salomaa, V., Iacoviello, L., Ferrario, M. M., Giampaoli, S., Kee, F., Thorand, B., Peters, A., Borchini, R., Jørgensen, T., Söderberg, S., Sans, S., Tunstall-Pedoe, H., Kuulasmaa, K., Renné, T., Lackner, K. J., Worster, A., Body, R., Ekelund, U., Kavsak, P. A., Keller, T., Lindahl, B., Wild, P., Giannitsis, E., Than, M., Cullen, L. A., Mills, N. L., Mueller, C., Zeller, T., Westermann, D. & Blankenberg, S., 27 Jun 2019, In : New England Journal of Medicine. 380, 26, p. 2529-2540 12 p.

Research output: Contribution to journal › Article

Troponin

Myocardial Infarction

Troponin I

Hospital Emergency Service

Troponin T

1 Citation (Scopus)

A randomized controlled efficacy trial of a smoking prevention programme with Grade 8 students in high schools

Thurston, A., Dunne, L., Kee, F., Gildea, A., Craig, N., Stark, P. & Lazenbatt, A., 2019, In : International Journal of Educational Research. 93, p. 23-32 10 p.

Research output: Contribution to journal › Article

smoking

school grade

school

student

arms control

A randomized non-inferiority trial of wearing adjustable glasses versus standard and ready-made spectacles among Chinese school children: WEAR (Wearability and Evaluation of Adjustable Refraction) III

Wang, C., Zhang, G., Tang, B., Jin, L., Huang, W., Wang, X., Chen, T., Xiao, B., Zhu, W., Wang, J., Zhou, Z., Tang, Z., Liang, Y., Crescioni, M., Wilson, D., McAneney, H., Silver, J. D., Moore, B. & Congdon, N., 14 Aug 2019, In : Ophthalmology.

Research output: Contribution to journal › Article

A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks-results from the Lassa fever pilot

Sigfrid, L., Moore, C., Salam, A. P., Maayan, N., Hamel, C., Garritty, C., Lutje, V., Buckley, B., Soares-Weiser, K., Marshall, R., Clarke, M. & Horby, P., 11 Jun 2019, In : BMC Medicine. 17, 1, p. 107

Research output: Contribution to journal › Article

Open Access

File

Lassa Fever

Disease Outbreaks

Research

Software

Philippines

Are volunteering and caregiving associated with suicide risk? A Census-based longitudinal study

Rosato, M., Tseliou, F., Wright, D. M., Maguire, A. & O'Reilly, D., 11 Oct 2019, In : BMC Psychiatry. 19, 1, 296.

Research output: Contribution to journal › Article

Open Access

File

Censuses

Suicide

Longitudinal Studies

Mental Health

Caregivers

Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi

Msefula, C. L., Olgemoeller, F., Jambo, N., Segula, D., Van Tan, T., Nyirenda, T. S., Nedi, W., Kennedy, N., Graham, M., Henrion, M. Y. R., Baker, S., Feasey, N., Gordon, M. & Heyderman, R. S., 17 Jul 2019, In : PLoS Neglected Tropical Diseases. 13, 7, 16 p., e0007539.

Research output: Contribution to journal › Article

Open Access

Malawi

Hospitalized Child

Salmonella

Fever

Polymerase Chain Reaction

1 Citation (Scopus)

Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis

Noack, F., Pataskar, A., Schneider, M., Buchholz, F., Tiwari, V. K. & Calegari, F., Apr 2019, In : Life science alliance. 2, 2, 15 p., e201900331.

Research output: Contribution to journal › Article

Open Access

File

DNA Methylation

Methylation

Cytosine

Transcription Factors

Neural Stem Cells

1 Citation (Scopus)

Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis

Sherrard, L. J., Einarsson, G. G., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S. J., Gilpin, D. F., Downey, D. G., Reid, A., McElvaney, N. G., Boucher, R. C., Muhlebach, M. S., Elborn, J. S. & Tunney, M. M., 21 Mar 2019, In : Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Research output: Contribution to journal › Article

Cystic Fibrosis

Sputum

Biota

Microbiota

Logistic Models

1 Citation (Scopus)

Assistive technology: Understanding the needs and experiences of individuals with autism spectrum disorder and/or intellectual disability in Ireland and the UK

O’Neill, S. J., Smyth, S., Smeaton, A. & O’Connor, N. E., 22 Jan 2019, Assistive Technology 9 p.

Research output: Contribution to specialist publication › Article

Self-Help Devices

Ireland

Intellectual Disability

Caregivers

Self Care

Association Between Aspirin Use and Biliary Tract Cancer Survival

Jackson, S. S., Pfeiffer, R., Liu, Z., Anderson, L., Tsai, H-T., Gadalla, S. & Koshiol, J., 17 Oct 2019, In : JAMA oncology.

Research output: Contribution to journal › Article

Biliary Tract Neoplasms

Aspirin

Survival

Neoplasms

Ampulla of Vater

2 Citations (Scopus)

Association of Immune Marker Changes With Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

Landgren, O., Hofmann, J. N., McShane, C., Santo, L., Korde, N., Hultcrantz, M., Mailankody, S., Kazandjian, D., Murata, K., Thoren, K., Ramanathan, L., Dogan, A., Rustad, E., Lu, S. X., Akhlaghi, T., Kristinsson, S. Y., Björkholm, M., Devlin, S., Purdue, M. P., Pfeiffer, R. M. & 1 othersTuresson, I., 18 Jul 2019, In : JAMA Oncol.

Research output: Contribution to journal › Article

Monoclonal Gammopathy of Undetermined Significance

Multiple Myeloma

Biomarkers

Light

Odds Ratio