School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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33 Citations (Scopus)

(18)F-FDG PET-CT simulation for non-small-cell lung cancer: effect in patients already staged by PET-CT.

Hanna, G., Carson, K., Lynch, T., McAleese, J., Cosgrove, V., Eakin, R., Stewart, D. P., O'Sullivan, J. & Hounsell, A., 01 May 2010, In : International journal of radiation oncology, biology, physics. 77, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
lungs
positrons
tomography
cancer
8 Citations (Scopus)

(223)Ra and other bone-targeting radiopharmaceuticals-the translation of radiation biology into clinical practice

Turner, P. G. & O'Sullivan, J. M., 2015, In : British Journal of Radiology. 88, 1050, 9 p., 20140752.

Research output: Contribution to journalArticle

Radiobiology
Radiopharmaceuticals
Neoplasm Metastasis
Bone and Bones
Radioisotopes
2 Citations (Scopus)
86 Downloads (Pure)

(32)P in the treatment of myeloproliferative disorders

Lawless, S., McMullin, M. F., Cuthbert, R. & Houston, R., May 2016, In : The Ulster Medical Journal. 85, 2, p. 83-5 3 p.

Research output: Contribution to journalArticle

Open Access
File
Myeloproliferative Disorders
Leukemia
Essential Thrombocythemia
Northern Ireland
Polycythemia Vera

(D-Ser2)Oxm[Lys38-γ-glu-PAL] improves hippocampal gene expression and cognition in a mouse model of type 1 diabetes

Pathak, N. M., Irwin, N., Pathak, V. & Flatt, P. R., 31 Mar 2016, In : Journal of Experimental and Integrative Medicine. 6, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Oxyntomodulin
Type 1 Diabetes Mellitus
Cognition
Gene Expression
Streptozocin
4 Citations (Scopus)

(ICORG 05-03): prospective randomized non-inferiority phase III trial comparing two radiation schedules in malignant spinal cord compression (not proceeding with surgical decompression); the quality of life analysis

Lee, K. A., Dunne, M., Small, C., Kelly, P. J., McArdle, O., O'Sullivan, J., Hacking, D., Pomeroy, M., Armstrong, J., Moriarty, M., Clayton-Lea, A., Parker, I., Collins, C. D. & Thirion, P., 08 Feb 2018, In : Acta oncologica (Stockholm, Sweden).

Research output: Contribution to journalArticle

Surgical Decompression
Spinal Cord Compression
Ireland
Appointments and Schedules
Quality of Life
12 Citations (Scopus)

) A randomized controlled trial of a self-management psychosocial intervention for men with prostate cancer and their partners: a study protocol.

Mc Caughan, E., Prue, G., McSorley, O., Northouse, L., Schafenacker, A. & Parahoo, K., 2013, In : Journal of Advanced Nursing.

Research output: Contribution to journalArticle

277 Citations (Scopus)

[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents.

Cantello, B. C. C., Cawthorne, M. A., Cottam, G. P., Duff, P. T., Haigh, D., Hindley, R. M., Lister, C. A., Smith, S. A. & Thurlby, P. L., 1994, In : Journal of Medicinal Chemistry. 37(23), p. 3977-3985 9 p.

Research output: Contribution to journalArticle

troglitazone
Hypoglycemic Agents
rosiglitazone
pioglitazone
Benzoxazoles

[Inhibitory effect of caffeine on the potential-dependent calcium current in isolated intestinal smooth muscle cells]

Zholos, A., 1989, In : Doklady Akademii nauk SSSR. 309(1), p. 240-243 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

[Non-selective cationic current--the basis of depolarization in smooth muscle]

Pucovsky, V. & Bauer, V., 2000, In : Bratislava Medical Journal. 101, 6, p. 331-339 9 p.

Research output: Contribution to journalArticle

[Regenerative calcium-induced liberation of calcium from intracellular stores in smooth muscle cells]

Zholos, A., 1991, In : Doklady Akademii nauk SSSR. 317(3), p. 735-738 4 p.

Research output: Contribution to journalArticle

[Smooth muscle preparations as models for studies of drug effects on organs]

Bauer, V., Matyas, S., Gergel, D., Juranek, I., Rekalov, V. & Pucovsky, V., 1995, In : Ceskoslovenska fysiologie. 44, p. 3-5 3 p.

Research output: Contribution to journalArticle

070 “physician exercise thyself”-a lifestyle imperative for doctors in General Practice?

Hart, N., 2005, In : Family Practice. 22, p. 48-49 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

1/f(alpha) fluctuations in a ricepile model

Zhang, S-D., 2000, In : Physical Review E. 61, p. 5983-5986 4 p.

Research output: Contribution to journalArticle

piles
Power Spectrum
Fluctuations
power spectra
Slope
29 Citations (Scopus)

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Lambrechts, D., Truong, T., Justenhoven, C., Humphreys, M. K., Wang, J., Hopper, J. L., Dite, G. S., Apicella, C., Southey, M., Schmidt, M. K., Broeks, A., Cornelissen, S., van Hien, R., Sawyer, E., Tomlinson, I., Kerin, M., Miller, N., Milne, R. L., Zamora, M. P., Pérez, J. I. A. & 31 others, Benítez, J., Hamann, U., Ko, Y-D., Brüning, T., Chang-Claude, J., Eilber, U., Hein, R., Nickels, S., Flesch-Janys, D., Wang-Gohrke, S., John, E. M., Miron, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Chenevix-Trench, G., Beesley, J., Chen, X., Menegaux, F., Cordina-Duverger, E., Shen, C-Y., Yu, J-C., Wu, P-E., Hou, M-F., Andrulis, I. L., Selander, T., Glendon, G., Mulligan, A. M., Orr, N. & GENICA Network, Jul 2012, In : Human Mutation. 33, 7, p. 1123-32 10 p.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Estrogen Receptors
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 9
1 Citation (Scopus)

123I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults

Roberts, G., Lloyd, J. J., Petrides, G. S., Donaghy, P., Kane, J., Durcan, R., Lawley, S., Howe, K., Sims, A., Taylor, J-P., O'Brien, J. T. & Thomas, A. J., 21 Mar 2019, In : Annals of Nuclear Medicine.

Research output: Contribution to journalArticle

Corpus Striatum
Lewy Body Disease
Nortropanes
Software
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
6 Citations (Scopus)

123I-MIBG scintigraphy utility and cut-off value in a clinically representative dementia cohort

Kane, J. P. M., Roberts, G., Petrides, G. S., Lloyd, J. J., O'Brien, J. T. & Thomas, A. J., 26 Jan 2019, In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Open Access
File
3-Iodobenzylguanidine
Radionuclide Imaging
Dementia
Mediastinum
Lewy Body Disease

16th All Ireland social medicine meeting - Proceedings of meeting held 21-23 March, 1997

the HARP-2 Investigators, for the Irish Critical Care Trials Group, 01 Jul 1998, In : Irish journal of medical science. 167, 9 Supplement, p. 27-32 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

18F-fluorodeoxyglucose positron emission tomography/computed tomography-based radiotherapy target volume definition in non-small-cell lung cancer: delineation by radiation oncologists vs. joint outlining with a PET radiologist?

Hanna, G., Carson, K. J., Lynch, T., McAleese, J., Cosgrove, V. P., Eakin, R. L., Stewart, D. P., Zatari, A., O'Sullivan, J. & Hounsell, A., 04 Nov 2010, In : International journal of radiation oncology, biology, physics. 78, 4, p. 1040-1051 12 p.

Research output: Contribution to journalArticle

delineation
Fluorodeoxyglucose F18
Non-Small Cell Lung Carcinoma
lungs
radiation therapy
70 Citations (Scopus)

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

Stevens, K. N., Fredericksen, Z., Vachon, C. M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomäki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H-P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y-D., Fischer, H-P., Schmutzler, R. K. & 31 others, Meindl, A., Bartram, C. R., Schott, S., Engel, C., Godwin, A. K., Weaver, J., Pathak, H. B., Sharma, P., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Miron, P., Yannoukakos, D., Stavropoulou, A., Fountzilas, G., Gogas, H. J., Swann, R., Dwek, M., Perkins, A., Milne, R. L., Benítez, J., Zamora, M. P., Pérez, J. I. A., Bojesen, S. E., Nielsen, S. F., Nordestgaard, B. G., Flyger, H., Guénel, P., Orr, N. & GENICA Network, 01 Apr 2012, In : Cancer Research. 72, 7, p. 1795-803 9 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Breast Neoplasms
Estrogen Receptors
Progesterone Receptors
Confidence Intervals

1H and (13)C NMR spectroscopic analysis of human saliva

Lynch, E., Silwood, C. J., Claxson, A. W. & Grootveld, M. C., Jan 2002, In : Journal of Dental Research. 81(6), p. 422-427 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

1H NMR investigations of the molecular nature of low-molecular-mass calcium ions in biofluids

Lynch, E., Silwood, C. L. & Grootveld, M., Jan 2002, In : Journal of Biological Inorganic Chemistry. 1, 1-2, p. 46-57 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

1st L. H. Gray Workshop. Measurement of radiation-induced damage.

Mcmillan, T. J., Oneill, P., Peacock, J. H. & Prise, K., 1990, In : International journal of radiation biology. 58, p. 391-396 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

2.9 Vegetarian Diets

McEvoy, C. T. & Woodside, J. V., 2015, In : World Review of Nutrition and Dietetics. 113, p. 134-8 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
85 Downloads (Pure)

2-hydroxylation of Acinetobacter baumannii lipid A contributes to virulence

Bartholomew, T. L., Kidd, T. J., Sá Pessoa, J., Conde Álvarez, R. & Bengoechea, J. A., 25 Mar 2019, In : Infection and Immunity.

Research output: Contribution to journalArticle

Open Access
File
Acinetobacter baumannii
Lipid A
Hydroxylation
Virulence
Interleukin-10
6 Citations (Scopus)

2q34-qter duplication and 4q34.2-qter deletion in a patient with developmental delay.

Rashidi-Nezhad, A., Parvaneh, N., Farzanfar, F., Azimi, C., Harewood, L., Akrami, SM. & Reymond, A., Mar 2012, In : EUROPEAN JOURNAL OF MEDICAL GENETICS.

Research output: Contribution to journalArticle

Pierre Robin Syndrome
Congenital Heart Defects
Chromosomes, Human, Pair 4
Developmental Disabilities
Intellectual Disability
151 Citations (Scopus)

3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

Smith, D. G., Buffet, M., Fenwick, A. E., Haigh, D., Ife, R. J., Saunders, M., Slingsby, B. P., Stacey, R. & Ward, R. W., 12 Mar 2001, In : Bioorganic & Medicinal Chemistry Letters. 11, 5, p. 635-639 5 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Protein Kinases
55 Citations (Scopus)

3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

Wells-Knecht, K. J., Lyons, T. J., McCance, D. R., Thorpe, S. R., Feather, M. S. & Baynes, J. W., Sep 1994, In : Diabetes. 43, 9, p. 1152-6 5 p.

Research output: Contribution to journalArticle

Urine
Proteins
Glycemic Index
Dermatoglyphics
Body Fluids

3-Dimensional cultures from human and rat osteoblast.

Manduca, P., Dickson, G., Poggi, S. & Ferrera, D., 2000, In : Journal of Bone and Mineral Research. 15, p. S503-S503 1 p.

Research output: Contribution to journalArticle

13 Downloads (Pure)
Open Access
File
Polyurethanes
Levofloxacin
Elasticity
Pharmaceutical Preparations
Surgical Mesh

3D targeting of a porcine ureter tissue fragments with a charged-particle microbeam

Belyakov, O. V., Folkard, M., Mothersill, C., Prise, K. & Michael, B. D., 2002, In : Radiation Research. 158, p. 383-384 2 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

4-Amino-1,8-naphthalimide-based Tröger's bases as high affinity DNA targeting fluorescent supramolecular scaffolds

Veale, E. B., Frimannsson, D. O., Lawler, M., Gunnlaugsson, T. & Lawler, M., 17 Sep 2009, In : Organic Letters. 11, 18, p. 4040-3 4 p.

Research output: Contribution to journalArticle

Naphthalimides
leukemias
K562 Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
cultured cells

5-aryl-pyrazolo[3,4-b]pyridazines: Potent inhibitors of glycogen synthase kinase-3 (GSK-3)

Witherington, J., Bordas, V., Haigh, D., Hickey, D. M. B., Ife, R. J., Rawlings, A. D., Slingsby, B. P., Smith, D. G. & Ward, R. W., 05 May 2003, In : Bioorganic & Medicinal Chemistry Letters. 13, 9, p. 1581-1584 4 p.

Research output: Contribution to journalArticle

Pyridazines
Glycogen Synthase Kinase 3
X ray crystallography
X Ray Crystallography
Nitrogen
18 Citations (Scopus)

5-Fluorouracil: identification of novel downstream mediators of tumour response

Boyer, J., Maxwell, P. J., Longley, D. B. & Johnston, P. G., 2004, In : Anticancer Research. 24, 2A, p. 417-23 7 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Fluorouracil
Breast Neoplasms
Pharmaceutical Preparations
Neoplasms
2435 Citations (Scopus)

5-Fluorouracil: mechanisms of action and clinical strategies

Longley, D. B., Harkin, D. P. & Johnston, P. G., May 2003, In : Nature Reviews. Cancer. 3, p. 330-338 9 p.

Research output: Contribution to journalArticle

Fluorouracil
Drug Therapy
DNA Fingerprinting
Oligonucleotide Array Sequence Analysis
Drug Resistance
39 Citations (Scopus)

5-HT(2C) receptor gene polymorphisms associated with antipsychotic drug action alter promoter activity.

Hill, M. J. & Reynolds, G., 14 May 2007, In : Brain Research. 1149C, 1, p. 14-17 4 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

5-nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in vitro and in vivo

Leonard, S. W., Bruno, R. S., Paterson, E., Schock, B., Atkinson, J., Bray, T. M., Cross, C. E. & Traber, M. G., Dec 2003, In : Free Radical Biology and Medicine. 35, p. 1560-1567 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

5-year incidence of age-related maculopathy in the Reykjavik Eye Study

Jonasson, F., Arnarsson, A., Peto, T., Sasaki, H., Sasaki, K. & Bird, A. C., Jan 2005, In : Ophthalmology. 112, 1, p. 132-8 7 p.

Research output: Contribution to journalArticle

Macular Degeneration
Incidence
Geographic Atrophy
Confidence Intervals
Population
13 Citations (Scopus)

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

Warren, H., Dudbridge, F., Fletcher, O., Orr, N., Johnson, N., Hopper, J. L., Apicella, C., Southey, M. C., Mahmoodi, M., Schmidt, M. K., Broeks, A., Cornelissen, S., Braaf, L. M., Muir, K. R., Lophatananon, A., Chaiwerawattana, A., Wiangnon, S., Fasching, P. A., Beckmann, M. W., Ekici, A. B. & 31 others, Schulz-Wendtland, R., Sawyer, E. J., Tomlinson, I., Kerin, M., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Guénel, P., Truong, T., Laurent-Puig, P., Mulot, C., Bojesen, S. E., Nielsen, S. F., Flyger, H., Nordestgaard, B. G., Milne, R. L., Benítez, J., Arias-Pérez, J-I., Zamora, M. P., Anton-Culver, H., Ziogas, A., Bernstein, L., Dur, C. C., Brenner, H., Müller, H., Arndt, V., Langheinz, A., Meindl, A., Golatta, M. & GENICA Network, Oct 2012, In : Cancer Epidemiology Biomarkers & Prevention. 21, 10, p. 1783-91 9 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Alleles
Confidence Intervals
Genome-Wide Association Study
4 Citations (Scopus)

A/H1N1 pandemic: misdiagnosis in the time of meningitis

Bourke, T. W. & Shields, M. D., 25 Aug 2009, In : BMJ (Clinical Research Edition). 339, p. b3423 1 p.

Research output: Contribution to journalArticle

5 Downloads (Pure)
Open Access
File
Bronchiectasis
Cost-Benefit Analysis
Clinical Trials
Standard of Care
Sputum
248 Citations (Scopus)

A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: report 3

Rajendram, R., Fraser-Bell, S., Kaines, A., Michaelides, M., Hamilton, R. D., Esposti, S. D., Peto, T., Egan, C., Bunce, C., Leslie, R. D. & Hykin, P. G., Aug 2012, In : Archives of Ophthalmology. 130, 8, p. 972-9 8 p.

Research output: Contribution to journalArticle

Macular Edema
Laser Therapy
Randomized Controlled Trials
Diabetic Retinopathy
Visual Acuity
44 Citations (Scopus)

A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells

Parker, J., Sarlang, S., Thavagnanam, S., Williamson, G., O'donoghue, D., Villenave, R., Power, U., Shields, M., Heaney, L. & Skibinski, G., Jan 2010, In : Pediatric Research. 67, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

Epithelium
Goblet Cells
Pediatrics
Asthma
Tight Junctions
12 Citations (Scopus)
134 Citations (Scopus)

A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders.

Zufferey, F., Sherr, EH., Beckmann, ND., Hanson, E., Maillard, AM., Hippolyte, L., Macé, A., Ferrari, C., Kutalik, Z., Andrieux, J., Aylward, E., Barker, M., Bernier, R., Bouquillon, S., Conus, P., Delobel, B., Faucett, WA., Goin-Kochel, RP., Grant, E. & Harewood, L., Oct 2012, In : Journal of Medical Genetics.

Research output: Contribution to journalArticle

Intelligence
Head
Speech Therapy
Psychiatry
Comorbidity
269 Citations (Scopus)

A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

Mandola, M. V., Stoehlmacher, J., Zhang, W., Groshen, S., Yu, M. C., Iqbal, S., Lenz, H-J. & Ladner, R. D., May 2004, In : Pharmacogenetics. 14, 5, p. 319-27 9 p.

Research output: Contribution to journalArticle

Thymidylate Synthase
Messenger RNA
Genes
3' Untranslated Regions
Luciferases
13 Citations (Scopus)
Galantamine
Alzheimer Disease
Equipment and Supplies
Behavioral Symptoms
Urban Hospitals

A 6 year-old boy was referred from a district hospital with congestive cardiac failure

Selman, A., Molyneux, E. & Kennedy, N., Dec 2013, In : Malawi medical journal : the journal of Medical Association of Malawi. 25, 4, p. 121-2 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A balanced reciprocal translocation in a case of hypomelanosis of Ito with confirmation of mosaicism using buccal cell interphase FISH.

Keng, WT., Harewood, L., Grace, E., Paxton, C., Lam, WW. & Fitzpatrick, DR., May 2006, In : American Journal of Medical Genet Part A.

Research output: Contribution to journalArticle