School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Article
2019

Hormone replacement therapy and the risk of melanoma in post-menopausal women

Hicks, B., Bruun Kristensen, K., Arnspang Pedersen, S., Rosenkrantz Hölmich, L. & Pottegård, A., 05 Dec 2019, In : Human reproduction.

Research output: Contribution to journalArticle

Hormone Replacement Therapy
Melanoma
Confidence Intervals
Odds Ratio
Prescriptions
1 Citation (Scopus)
15 Downloads (Pure)

How do we evaluate the role of focal/grid photocoagulation in the treatment of diabetic macular ede-ma?

Blindbæk, S. L., Peto, T. & Grauslund, J., 29 Apr 2019, In : Acta Ophthalmologica. 8 p.

Research output: Contribution to journalArticle

Open Access
File
Light Coagulation
Macular Edema
Vascular Endothelial Growth Factor A
Lasers
Therapeutics

How to use perianal examination in children

Bourke, T., Colvin, D., Mallett, P., McMahon, N., Thompson, A. & McCallion, W., 09 May 2019, In : Archives of disease in childhood. Education and practice edition.

Research output: Contribution to journalArticle

43 Downloads (Pure)
Open Access
File
androgen
Androgen Receptors
Health
Acids
acid
53 Downloads (Pure)

Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation

McComb, J., Mills, I., Muller, M., Berntsen, H. F., Elisabeth Zimmer, K., Ropstad, E., Verhaegen, S. & Connolly, L., 27 Aug 2019, In : Environment International. 132, 105083, p. 132 11 p.

Research output: Contribution to journalArticle

Open Access
File
androgen
translocation
blood
assay
gene
3 Citations (Scopus)
112 Downloads (Pure)
Open Access
File
Acidosis
Stem cells
Mesenchymal Stromal Cells
Repair
Lung

Identification and SAR exploration of a novel series of Legumain inhibitors

Eddie, S. L., Gregson, A., Graham, E., Burton, S., Harrison, T., Burden, R., Scott, C. J., Mullan, P. B. & Williams, R., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry Letters. 29, 12, p. 1546-1548 3 p.

Research output: Contribution to journalArticle

asparaginylendopeptidase
Dipeptides
Molecules
Research
Experiments
44 Downloads (Pure)
Open Access
File
Myxococcus xanthus
O Antigens
Ligases
Lipopolysaccharides
Enzymes
56 Downloads (Pure)

Identifying patients’ support needs following critical illness: a scoping review of the qualitative literature

King, J., O'Neill, B., Ramsay, P., Linden, M., Darweish Medniuk, A., Outtrim, J. & Blackwood, B., 24 May 2019, In : Critical Care. 23, 12 p., 187.

Research output: Contribution to journalArticle

Open Access
File
Critical Care
Critical Illness
Survivors
Social Support
Australasia
2 Citations (Scopus)
119 Downloads (Pure)

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine.

McLaren, JE., Clement, M., Marsden, M., Miners, KL., Llewellyn-Lacey, S., Grant, EJ., Rubina, A., Gimeno, B. S., Gostick, E., Stacey, MA., Orr, SJ., Stanton, RJ. & Humphreys, IR., 01 Feb 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 3, p. 943-955

Research output: Contribution to journalArticle

Open Access
File
Cytomegalovirus Vaccines
Attenuated Vaccines
Economic Inflation
Vaccines
Viruses
9 Downloads (Pure)

IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment

Augustine, J., Pavlou, S., Ali, I., Harkin, K., Ozaki, E., Campbell, M., Stitt, A. W., Xu, H. & Chen, M., 03 Dec 2019, In : Journal of neuroinflammation. 16, 15 p., 251.

Research output: Contribution to journalArticle

Open Access
File
Retinal Detachment
Inflammation
Glial Fibrillary Acidic Protein
Interleukin-1
Macrophages
4 Citations (Scopus)

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J., Whyte, M. K. B. & 1 others, Walmsley, S. R., 08 Mar 2019, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Acute Lung Injury
Neutrophils
Interleukin-4
Adult Respiratory Distress Syndrome
Interleukin-13

Imaging in pregnancy

Eastwood, K-A. & Mohan, A. R., 07 Aug 2019, In : The Obstetrician and Gynaecologist.

Research output: Contribution to journalArticle

Pregnancy
Safety
Gadolinium
Ionizing Radiation
Informed Consent
9 Citations (Scopus)

Immediate Transfusion in African Children with Uncomplicated Severe Anemia

TRACT Group, 01 Aug 2019, In : New England Journal of Medicine. 381, 5, p. 407-419 13 p.

Research output: Contribution to journalArticle

Anemia
Random Allocation
Control Groups
Length of Stay
Hemoglobins
2 Citations (Scopus)
118 Downloads (Pure)

Immune Activation by DNA Damage Predicts Response to Chemotherapy and Survival in Oesophageal Adenocarcinoma

Turkington, R., Knight, L., Blayney, J., Secrier, M., Douglas, R., Parkes, E., Sutton, E., Stevenson, L., McManus, D., Halliday, S., McCavigan, A., Logan, G., Walker, S., Steele, C., Perner, J., Bornscein, J., MacRae, S., Miremadi, A., mccarron, E., McQuaid, S. & 10 others, Arthur, K., James, J., Eatock, M., O'Neill, R., Noble, F., Underwood, T., Harkin, D., Salto-Tellez, M., Fitzgerald, R. C. & Kennedy, R., 09 Mar 2019, In : Gut. 10 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Damage
Adenocarcinoma
Drug Therapy
Survival
Adjuvant Chemotherapy
4 Citations (Scopus)
59 Downloads (Pure)

Immune regulation in the aging retina

Chen, M., Luo, C., Zhao, J., Devarajan, G. & Xu, H., Mar 2019, In : Progress in Retinal and Eye Research. 69, p. 159-172 14 p.

Research output: Contribution to journalArticle

Open Access
File
Retina
Blood-Retinal Barrier
Macular Degeneration
Microglia
Diabetic Retinopathy
1 Citation (Scopus)

Impact of patient characteristics on edentulous subjects’ preferences for prosthodontic rehabilitation with implants

Rodrigues Leles, C., Rocha Dias, D., Eduardo Nogueira, T., McKenna, G., Schimmel, M. & Jordao, L. M. R., 10 Feb 2019, In : clinical oral implants research.

Research output: Contribution to journalArticle

Prosthodontics
Dentures
Rehabilitation
Mandible
Oral Health

Impact of retinal ischemia on functional and anatomical outcomes following antivascular endothelial growth factor therapy in patients with retinal vein occlusion

Khayat, M., Wright, D., Yeong, J., Xu, D., Donley, C., Lakshmipathy, G. R., Low, M. K., White, N., Williams, M. & Lois, N., 30 May 2019, In : Retina.

Research output: Contribution to journalArticle

Endothelial Growth Factors
Retinal Vein Occlusion
Ischemia
Retinal Vein
Therapeutics
1 Citation (Scopus)
96 Downloads (Pure)

Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: A trainee-led multicentre audit and service evaluation

O'Donnell, R. L., Angelopoulos, G., Beirne, J. P., Biliatis, I., Bolton, H., Bradbury, M., Craig, E., Gajjar, K., Mackintosh, M. L., Macnab, W., Madhuri, T. K., McComiskey, M., Myriokefalitaki, E., Newton, C. L., Ratnavelu, N., Taylor, S. E., Thangavelu, A., Rhodes, S. A., Crosbie, E. J., Edmondson, R. J. & 1 others, Wan, Y. L. L., 24 Jan 2019, In : BMJ Open. 9, 1, 8 p., e024853.

Research output: Contribution to journalArticle

Open Access
File
Surgical Wound Infection
Gynecologic Surgical Procedures
Neoplasms
Laparotomy
Wounds and Injuries
3 Citations (Scopus)
4 Downloads (Pure)

Impact of variation in cancer registration practice on observed international cancer survival differences between International Cancer Benchmarking Partnership (ICBP) jurisdictions

Eden, M., Harrison, S., Griffin, M., Lambe, M., Pettersson, D., Gavin, A., Brewster, D. H., Lin, Y., Johannesen, T. B., Milne, R. L., Farrugia, H., Nishri, D., King, M-J., Huws, D. W., Warlow, J., Turner, D., Earle, C. C., Peake, M. & Rashbass, J., 01 Feb 2019, In : Cancer epidemiology. 58, p. 184-192

Research output: Contribution to journalArticle

Open Access
File
Benchmarking
Neoplasms
Sweden
Victoria
Ontario
2 Citations (Scopus)
50 Downloads (Pure)

Impact of various types of near work and time spent outdoors at different times of day on visual acuity and refractive error among Chinese school-going children

Guan, H., Yu, N. N., Wang, H., Boswell, M., Shi, Y., Rozelle, S. & Congdon, N., 26 Apr 2019, In : PLoS ONE. 14, 4, 13 p., e0215827.

Research output: Contribution to journalArticle

Open Access
File
Refractive Errors
school children
Television
Visual Acuity
television
99 Downloads (Pure)
Open Access
File
Feasibility Studies
Art
Chronic Kidney Failure
Renal Dialysis
Randomized Controlled Trials
2 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
Electrocardiography
Cohort Studies
Retrospective Studies
Myocardial Infarction
MB Form Creatine Kinase
25 Downloads (Pure)

Improving the practice of cataract surgical outcome measurement

Congdon, N., Dodson, S., Chan, V. F., Mathenge, W. & Moo, E., 11 Feb 2019, In : Community Eye Health. 31, 104, p. 91-92 2 p.

Research output: Contribution to journalArticle

Open Access
File

Inactivating NF1 mutations are enriched in advanced breast cancer and contribute to endocrine therapy resistance

Pearson, A., Proszek, P. Z., Pascual, J., Fribbens, C., Shamsher, M. K., Kingston, B., O'Leary, B., Herrera-Abreu, M. T., Cutts, R. J., Garcia-Murillas, I., Bye, H., Walker, B. A., Gonzalez De Castro, D., Yuan, L., Jamal, S., Hubank, M., López-Knowles, E., Schuster, E. F., Dowsett, M., Osin, P. & 6 others, Nerurkar, A., Parton, M., Okines, A. F., Johnston, S. R. D., Ring, A. & Turner, N. C., 07 Oct 2019, In : Clinical Cancer Research.

Research output: Contribution to journalArticle

Breast Neoplasms
Mutation
Therapeutics
Neoplasms
Disease Progression
13 Citations (Scopus)

Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia

European Eye Epidemiology Consortium & EYE-RISK consortium, 01 Mar 2019, In : Ophthalmology. 126, 3, p. 393-406

Research output: Contribution to journalArticle

Macular Degeneration
HDL Lipoproteins
Epidemiology
Lipids
Odds Ratio
1 Citation (Scopus)
Dicarboxylic Acids
Choline
Eutectics
Oxalic Acid
chloride
20 Downloads (Pure)

Infantile Onset of Spinocerebellar Ataxia Type 5 (SCA-5) in a 6 Month Old with Ataxic Cerebral Palsy

Rea, G., Tirupathi, S., Williams, J., Clouston, P. & Morrison, P. J., 12 Nov 2019, In : Cerebellum (London, England).

Research output: Contribution to journalArticle

Open Access
File
Spinocerebellar Ataxias
Cerebral Palsy
Genetic Testing
Ataxia
Mutation

Influence of azithromycin and allograft rejection on the post–lung transplant microbiota

Spence, C. D., Vanaudenaerde, B., Einarsson, G. G., Mcdonough, J., Lee, A. J., Johnston, E., Verleden, G. M., Elborn, J. S., Dupont, L. J., Van Herck, A., Gilpin, D. F., Vos, R., Tunney, M. M. & Verleden, S. E., 21 Nov 2019, In : Journal of Heart and Lung Transplantation.

Research output: Contribution to journalArticle

Azithromycin
Microbiota
Allografts
Transplants
Lung

Influence of presbyopia on smartphone usage among Chinese adults: a population study

Wang, C., Wang, X., Jin, L., Tang, B., Zhu, W., Zhang, G., Chen, T., McAneney, H., Kassalow, J. & Congdon, N., 21 Oct 2019, In : Clinical and Experimental Ophthalmology. 47, 7, p. 909-917

Research output: Contribution to journalArticle

Presbyopia
Population
Visual Acuity
China
Aptitude
3 Citations (Scopus)
52 Downloads (Pure)
Open Access
File
Adenocarcinoma
Area Under Curve
Genetic Testing
Genetic Predisposition to Disease
Body Mass Index
42 Downloads (Pure)

In-school eyecare in special education settings has measurable benefits for children’s vision and behaviour

Black, S. A., McConnell, E. L., McKerr, L., McClelland, J. F., Little, J. A., Dillenburger, K., Jackson, A. J., Anketell, P. M. & Saunders, K. J., 01 Aug 2019, In : PLoS ONE. 14, 8, 19 p., e0220480.

Research output: Contribution to journalArticle

Open Access
File
special education
Special Education
Education
Health
teachers
1 Citation (Scopus)
92 Downloads (Pure)

Insight into the Hydration of Cationic Surfactants: A Thermodynamic and Dielectric Study of Functionalized Quaternary Ammonium Chlorides

Medoš, Ž., Plechkova, N. V., Friesen, S., Buchner, R. & Bešter-Rogač, M., 12 Mar 2019, In : Langmuir. 35, 10, p. 3759-3772 14 p.

Research output: Contribution to journalArticle

Open Access
File
Ammonium Chloride
ammonium chlorides
Cationic surfactants
Micelles
Hydration
25 Citations (Scopus)
346 Downloads (Pure)

Integrating Genomics into Healthcare: A Global Responsibility

Stark, Z., Dolman, L., Manolio, T. A., Ozenberger, B., Hill, S. L., Caulfied, M. J., Levy, Y., Glazer, D., Wilson, J., Lawler, M., Boughtwood, T., Braithwaite, J., Goodhand, P., Birney, E. & North, K. N., 03 Jan 2019, In : American Journal of Human Genetics. 104, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

Open Access
File
Genomics
Medicine
Delivery of Health Care
France
5 Citations (Scopus)
32 Downloads (Pure)

Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial

Brand, D. H., Tree, A. C., Ostler, P., van der Voet, H., Loblaw, A., Chu, W., Ford, D., Tolan, S., Jain, S., Martin, A., Staffurth, J., Camilleri, P., Kancherla, K., Frew, J., Chan, A., Dayes, I. S., Henderson, D., Brown, S., Cruickshank, C., Burnett, S. & 7 others, Duffton, A., Griffin, C., Hinder, V., Morrison, K., Naismith, O., Hall, E. & van As, N., 17 Sep 2019, In : Lancet Oncology.

Research output: Contribution to journalArticle

Open Access
File
Intensity-Modulated Radiotherapy
Radiosurgery
Prostatic Neoplasms
Radiotherapy
Radiation Oncology
1 Citation (Scopus)
63 Downloads (Pure)

Intensity Modulated Radiation Fields Induce Protective Effects and Reduce Importance of Dose-Rate Effects

Matsuya, Y., McMahon, S. J., Ghita, M., Yoshii, Y., Sato, T., Date, H. & Prise, K. M., 01 Jul 2019, In : Scientific Reports. 9, 1, p. 9483

Research output: Contribution to journalArticle

Open Access
File
Radiation
Cell Survival
Intensity-Modulated Radiotherapy
Survival
DNA
9 Citations (Scopus)
103 Downloads (Pure)

Intercellular Communication via Organelle Transfer in the Biology and Therapeutic Applications of Stem Cells

Murray, L. MA. & Krasnodembskaya, A. D., 01 Jan 2019, In : Stem Cells. 37, 1, p. 14-25

Research output: Contribution to journalArticle

Open Access
File
Organelles
Stem Cells
Therapeutics
Nanotubes
Lysosomes
16 Downloads (Pure)
Open Access
File
Critical Care
Deglutition Disorders
Meta-Analysis
Length of Stay
Clinical Trials
1 Citation (Scopus)

Interventions involving a major dietary component improve cognitive function in cognitively healthy adults: a systematic review and meta-analysis.

McEvoy, C., Leng, Y., Peeters, G., Kaup, A., Allen, I. & Yaffe, K., 02 Apr 2019, In : Nutrition Research.

Research output: Contribution to journalArticle

Cognition
Meta-Analysis
Confidence Intervals
Executive Function
Dementia

Interventions to improve psychosocial well-being in female brca-mutation carriers following risk-reducing surgery

Jeffers, L., Reid, J., Fitzsimons, D., Morrison, P. J. & Dempster, M., 09 Oct 2019, In : Cochrane Database of Systematic Reviews. 2019, 10, CD012894.

Research output: Contribution to journalArticle

Open Access
Mutation
Quality of Life
Mindfulness
Confidence Intervals
Ovariectomy

Intratumoral sterol-27-hydroxylase (CYP27A1) expression in relation to cholesterol synthesis and vitamin D signaling and its association with lethal prostate cancer

Khan, N. A., Stopsack, K., Allott, E. H., Gerke, T., Giovannucci, E. L., Mucci, L. A. & Kantoff, P. W., Jun 2019, In : Cancer Epidemiology Biomarkers & Prevention. 28, 6, p. 1052-1058 7 p.

Research output: Contribution to journalArticle

Cholestanetriol 26-Monooxygenase
Vitamin D
Prostatic Neoplasms
Cholesterol
4 alpha-glucanotransferase
60 Downloads (Pure)

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

Carroll, L. S., Uehara, H., Fang, D., Choi, S., Zhang, X., Singh, M., Sandhu, Z., Cummins, P. M., Curtis, T. M., Stitt, A. W., Archer, B. J. & Ambati, B. K., 03 Jun 2019, In : Investigative ophthalmology & visual science. 60, 7, p. 2494-2502 9 p.

Research output: Contribution to journalArticle

Open Access
File
Blood Vessels
Retina
Visual Acuity
Cartilage Oligomeric Matrix Protein
Angiopoietin-1

Intubation drug pack containing pre-filled syringes reduces the time to endotracheal intubation in a simulated paediatric emergency

Lawson, S., Flannigan, C., Green, C., Freeburn, L., Burns, A., McCann, J. & Bourke, T., 01 Mar 2019, In : BMJ Simulation and Technology Enhanced Learning.

Research output: Contribution to journalArticle

49 Downloads (Pure)

Investigating the clinical use of structured light plethysmography to assess lung function in children with neuromuscular disorders

Fleck, D., Curry, C., Donnan, K., Logue, O., Graham, K., Jackson, K., Keown, K., Winder, J., Shields, M. D. & Hughes, C. M., 26 Aug 2019, In : PLoS ONE. 14, 8, 19 p., e0221207.

Research output: Contribution to journalArticle

Open Access
File
Plethysmography
neuromuscular disorders
lung function
Light
Lung
61 Downloads (Pure)

Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial

Hall, A., Buckley, H. L., Flanagan, L., Gonzalez de Castro, D., Farnell, K., Moss, L., Gregory, R., Newbold, K., Du, Y., Flux, G. & Wadsley, J., 14 Jun 2019, In : BMC Cancer. 19, 10 p., 582.

Research output: Contribution to journalArticle

Open Access
File
Thyroid Neoplasms
Iodine
Therapeutics
Multicenter Studies
Disease-Free Survival
2 Citations (Scopus)
Longitudinal Studies
Prostatic Neoplasms
Psychology
Anxiety
Therapeutics
126 Downloads (Pure)

Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis

O'Leary, C., McGahon, M. K., Ashraf, S., McNaughten, J., Friedel, T., Cincolà, P., Barabas, P., Fernandez, J. A., Stitt, A. W., McGeown, J. G. & Curtis, T. M., 01 Aug 2019, In : Investigative ophthalmology & visual science. 60, 10, p. 3297-3309

Research output: Contribution to journalArticle

Open Access
File
Endothelial Cells
Ligation
Retina
Retinal Neovascularization
Staining and Labeling