School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Article
2019
56 Downloads (Pure)

Regional Variations in Quality of Survival Among Men with Prostate Cancer Across the United Kingdom

Donnelly, D., Gavin, A., Downing, A., Hounsome, L., Kearney, T., McNair, E., Allan, D., Huws, D., Wright, P., Selby, P. J., Kind, P., Watson, E., Wagland, R., Wilding, S., Butcher, H., Mottram, R., Allen, M., McSorley, O., Linda, S., Mason, M. D. & 3 others, Cross, W. R., Catto, J. W. F. & Glaser, A. W., 01 Jul 2019, In : European Urology. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Scotland
Prostatic Neoplasms
Northern Ireland
Survival
Wales

Regulators of A20 (TNFAIP3) - new drug-able targets in inflammation

Momtazi, G., Lambrecht, B. N., Naranjo, J. R. & Schock, B., 21 Feb 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. L-00335-2018R1.

Research output: Contribution to journalArticle

Cystic Fibrosis
Chronic Obstructive Pulmonary Disease
Transcription Factors
Asthma
Inflammation
9 Citations (Scopus)
222 Downloads (Pure)

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Non-Adherence in Severe Asthma

Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK), 15 Feb 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 4

Research output: Contribution to journalArticle

Open Access
File
Adrenal Cortex Hormones
Nitric Oxide
Asthma
Therapeutics
Technology

Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours

McDaid, W. J., Greene, M. K., Johnston, M. C., Pollheimer, E., Smyth, P., McLaughlin, K., Van Schaeybroeck, S., Straubinger, R. M., Longley, D. B. & Scott, C. J., 18 Oct 2019, In : Nanoscale. 13 p.

Research output: Contribution to journalArticle

Chemotherapy
Epidermal Growth Factor Receptor
Antibodies
Tumors
Nanoparticles
215 Downloads (Pure)

Resilience in medical doctors: a systematic review

McKinley, N., Karayanis, P. N., Convie, L., Clarke, M., Kirk, S. J. & Campbell, W. J., 29 Mar 2019, In : Postgraduate Medical Journal. 8 p., 136135.

Research output: Contribution to journalArticle

Open Access
File
Bibliographic Databases
Leisure Activities
PubMed
MEDLINE
Social Support
5 Downloads (Pure)
Open Access
File
Respiratory Syncytial Viruses
Asthma
Monoclonal Antibodies
Meta-Analysis
Bronchiolitis
39 Downloads (Pure)

Response to Imatinib therapy is inferior for e13a2 BCR-ABL1 transcript type in comparison to e14a2 transcript type in chronic myeloid leukaemia

Greenfield, G., McMullan, R., Robson, N., McGimpsey, J., Catherwood, M. & McMullin, M. F., 02 May 2019, In : EMJ Hematology. 19, p. 7

Research output: Contribution to journalArticle

Open Access
File
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Exons
Gene Fusion
Platelet Count
Population
14 Downloads (Pure)
Open Access
File
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Therapeutics
Expert Testimony
Cytogenetics
30 Citations (Scopus)
87 Downloads (Pure)

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

NCD Risk Factor Collaboration (NCD-RisC) & O'Reilly, D., 08 May 2019, In : Nature. 569, 7755, p. 260-264 5 p.

Research output: Contribution to journalArticle

Open Access
File
Body Mass Index
Obesity
Malnutrition
Urbanization
Africa South of the Sahara
2 Citations (Scopus)
89 Downloads (Pure)

Risk factors for Luminal A ductal carcinoma in situ (DCIS) and invasive breast cancer in the Carolina Breast Cancer Study

Williams, L. A., Casbas-Hernandez, P., Nichols, H. B., Tse, C. K., Allott, E. H., Carey, L. A., Olshan, A. F. & Troester, M. A., 25 Jan 2019, In : PLoS ONE. 14, 1, 11 p., e0211488.

Research output: Contribution to journalArticle

Open Access
File
Carcinoma, Intraductal, Noninfiltrating
breast neoplasms
carcinoma
risk factors
Breast Neoplasms
39 Downloads (Pure)

Risk factors for Violence-Related Injuries in Emergency Departments: A Danish Linkage Study

Murphy, S., Kruse, M., Elklit, A. & Brink, O., 15 May 2019, In : European Journal of Psychotraumatology. 10, 1, 8 p., 1606627.

Research output: Contribution to journalArticle

Open Access
File
Violence
Hospital Emergency Service
Wounds and Injuries
Substance-Related Disorders
Alcohols
91 Downloads (Pure)

Safety in Primary Care (SAP-C): A randomised, controlled feasibility study in two different healthcare systems

Madden, C., Lydon, S., Cupples, M., Hart, N., Curran, C., Murphy, A. & O'Connor, P., 30 Jan 2019, In : BMC Family Practice. 20, 22

Research output: Contribution to journalArticle

Open Access
File
Feasibility Studies
Primary Health Care
Climate
Patient Safety
Delivery of Health Care

Screening for diabetic retinopathy: new perspectives and challenges

Vujosevic, S., Aldington, S. J., Silva, P., Hernández, C., Scanlon, P., Peto, T. & Simó, R., 20 Nov 2019, (Accepted) In : The lancet. Diabetes & endocrinology.

Research output: Contribution to journalArticle

Psychotic Disorders
Prodromal Symptoms
MEDLINE
Mental Health
Population
1 Citation (Scopus)
49 Downloads (Pure)

Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection

Carlile, S. R., Shiels, J., Kerrigan, L., Delaney, R., Megaw, J., Gilmore, B. F., Weldon, S., Dalton, J. P. & Taggart, C. C., 15 Apr 2019, In : Scientific Reports. 9, 9 p., 6071.

Research output: Contribution to journalArticle

Open Access
File
Elapidae
Pseudomonas aeruginosa
Pneumonia
Inflammation
Elapid Venoms
10 Citations (Scopus)
26 Downloads (Pure)

Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study

Barbui, T., Ghirardi, A., Masciulli, A., Carobbio, A., Palandri, F., Vianelli, N., De Stefano, V., Betti, S., Di Veroli, A., Iurlo, A., Cattaneo, D., Delaini, F., Bonifacio, M., Scaffidi, L., Patriarca, A., Rumi, E., Casetti, I. C., Stephenson, C., Guglielmelli, P., Elli, E. M. & 21 others, Palova, M., Bertolotti, L., Erez, D., Gomez, M., Wille, K., Perez-Encinas, M., Lunghi, F., Angona, A., Fox, M. L., Beggiato, E., Benevolo, G., Carli, G., Cacciola, R., McMullin, M. F., Tieghi, A., Recasens, V., Marchetti, M., Griesshammer, M., Alvarez-Larran, A., Vannucchi, A. M. & Finazzi, G., 29 May 2019, In : Leukemia. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Second Primary Neoplasms
Case-Control Studies
Skin Neoplasms
Neoplasms
Hydroxyurea

Second cancers in MPN: Survival analysis from an international study

Marchetti, M., Ghirardi, A., Masciulli, A., Carobbio, A., Palandri, F., Vianelli, N., Rossi, E., Betti, S., Di Veroli, A., Iurlo, A., Cattaneo, D., Finazzi, G., Bonifacio, M., Scaffidi, L., Patriarca, A., Rumi, E., Casetti, I. C., Stephenson, C., Guglielmelli, P., Elli, E. M. & 24 others, Palova, M., Rapezzi, D., Erez, D., Gomez, M., Wille, K., Perez-Encinas, M., Lunghi, F., Angona, A., Fox, M. L., Beggiato, E., Benevolo, G., Carli, G., Cacciola, R., McMullin, M. F., Tieghi, A., Recasens, V., Isfort, S., Pane, F., De Stefano, V., Griesshammer, M., Alvarez-Larran, A., Vannucchi, A. M., Rambaldi, A. & Barbui, T., 22 Dec 2019, In : American Journal of Hematology.

Research output: Contribution to journalArticle

Second Primary Neoplasms
Survival Analysis
Neoplasms
Mortality
Cause of Death
20 Downloads (Pure)

Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial

Blackwood, B., Agus, A., Boyle, R., Clarke, M., Hemming, K., Jordan, J., Macrae, D., McAuley, D. F., McDowell, C., McIlmurray, L., Morris, K., Murray, M., Parslow, R., Peters, M., Tume, L. & Walsh, T., 10 Nov 2019, In : BMJ Open. 9, 11, 9 p., e031630.

Research output: Contribution to journalArticle

Open Access
File
Weaning
Artificial Respiration
Ventilation
Pediatric Intensive Care Units
Research Ethics Committees
84 Downloads (Pure)
Open Access
File
Cell Aging
Essential Genes
Real-Time Polymerase Chain Reaction
Genes
Gene Expression

Sending messages in moving cells: mRNA localization and the regulation of cell migration

Herbert, S. P. & Costa, G., Oct 2019, In : Essays in Biochemistry. 63, 5, p. 595-606 12 p.

Research output: Contribution to journalArticle

Cell Movement
Cells
Cell Polarity
Messenger RNA
Tissue homeostasis
2 Citations (Scopus)
108 Downloads (Pure)

Serum amyloid A levels are associated with polymorphic variants in the serum amyloid A 1 and 2 genes

Griffiths, K., Maxwell, A. P., McCarter, R. V., Nicol, P., Hogg, R. E., Harbinson, M. & McKay, G. J., 09 Mar 2019, In : Irish journal of medical science.

Research output: Contribution to journalArticle

Open Access
File
Serum Amyloid A Protein
Genes
Confidence Intervals
vif Genes
HDL Lipoproteins
1 Citation (Scopus)
Liver Neoplasms
Meta-Analysis
Iron
Biomarkers
Serum
74 Downloads (Pure)

Serum Lipids Prior to Starting Androgen Deprivation Therapy and Risk of Castration-Resistant Prostate Cancer and Metastasis: Results from the SEARCH Database

Dambal, S., Howard, L. E., Allott, E. H., Aronson, W. J., Kane, C. J., Amling, C. L., Cooperberg, M. R., Terris, M. K. & Freedland, S. J., 20 Aug 2019, In : Journal of Urology.

Research output: Contribution to journalArticle

Open Access
File
Castration
Androgens
Prostatic Neoplasms
Databases
Neoplasm Metastasis
16 Downloads (Pure)
Open Access
File
Xanthophylls
Glomerular Filtration Rate
Kidney
Lutein
Tocopherols
36 Downloads (Pure)

Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increasedself-management and remote patient monitoring through mHealth solutions

Alqudah, A., McMullan, P., Todd, A., O’Doherty, C., McVey, A., McConnell, M., O’Donoghue, J., Gallagher, J., Watson, C. & McClements, L., 13 Sep 2019, In : BMC Health Services Research.

Research output: Contribution to journalArticle

Open Access
File
Maternity Hospitals
Telemedicine
Physiologic Monitoring
Pregnant Women
Pregnancy

Social behaviour and making attachments: a report from the fifth 'Young Microbiologists Symposium on Microbe Signalling, Organisation and Pathogenesis'

An, S-Q., Ding, Y-C., Faber, F., Hobley, L. & Sá-Pessoa, J., 01 Feb 2019, In : Microbiology (Reading, England). 165, 2, p. 138-145 8 p.

Research output: Contribution to journalArticle

Social Behavior
Microbiology
Organizations
Northern Ireland
Posters

Social inclusion in the Irish health context: Policy and stakeholder mapping

O'Donnell, P., O'Donovan, D. & Elmusharaf, K., 13 Jul 2019, In : Irish journal of medical science.

Research output: Contribution to journalArticle

Health Policy
Public Policy
Health
Literature
Social Welfare
2 Citations (Scopus)
46 Downloads (Pure)

Social network interventions for health behaviours and outcomes: A systematic review and meta-analysis

Hunter, R., de la Haye, K., Murray, J., Badham, J., Valente, T., Clarke, M. & Kee, F., 03 Sep 2019, In : PLoS Medicine. 16, 9, 25 p., e1002890.

Research output: Contribution to journalArticle

Open Access
File
Health Behavior
Social Support
Meta-Analysis
Reproductive Health
Health

Social norm feedback reduces primary care antibiotic prescribing in a regression discontinuity study

Bradley, D. T., Allen, S. E., Quinn, H., Bradley, B. & Dolan, M., Sep 2019, In : Journal of Antimicrobial Chemotherapy. 74, 9, p. 2797–2802 6 p.

Research output: Contribution to journalArticle

Primary Health Care
Anti-Bacterial Agents
Northern Ireland
Age Groups
Health Priorities
5 Citations (Scopus)
91 Downloads (Pure)

Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis

BIOS Consortium, 14 Apr 2019, In : Aging. 11, 7, p. 2045-2070

Research output: Contribution to journalArticle

Open Access
File
Epigenomics
Habits
Life Style
Cohort Studies
Biomarkers

Socioeconomic Position and Health Outcomes Following Critical Illness: A Systematic Review

Jones, J. R. A., Berney, S., Connolly, B., Waterland, J. L., Denehy, L., Griffith, D. M. & Puthucheary, Z. A., 01 Jun 2019, In : Critical Care Medicine. 47, 6, p. e512-e521 10 p.

Research output: Contribution to journalArticle

Critical Illness
Quality of Life
Survival
Health
Mortality

Solid advice: complementary feeding experiences and use of guidance among disadvantaged parents in two countries

Tully, L., Allen-Walker, V., Spyreli, E., McHugh, S., Woodside, J. V., Kearney, P. M., McKinley, M. C., Dean, M. & Kelly, C., 25 Feb 2019, In : Maternal & child nutrition.

Research output: Contribution to journalArticle

Infant Nutritional Physiological Phenomena
Vulnerable Populations
Parents
Focus Groups
Social Class
44 Downloads (Pure)

So You Want to be aClinical Research Fellow

Addy, C., Bradley, J., McGarvey, L., Elborn, J. S. & Downey, D., Jan 2019, In : The Ulster Medical Journal. 88, 1, p. 60-61 2 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
41 Downloads (Pure)

Sports-related concussion (SRC) assessment in road cycling: a systematic review and call to action

Elliott, J., Anderson, R., Heron, N. & Collins, S., 14 Apr 2019, In : BMJ Open Sport & Exercise Medicine . 5, 5 p., e000525.

Research output: Contribution to journalArticle

Open Access
File
Sports
Amnesia
Unconsciousness
MEDLINE
Consensus
46 Downloads (Pure)

Sports-Related Concussion (SRC) in Road Cycling – the RoadsIde head injury assessment (RIDE) for Elite Road Cycling

Elliott, J., Jones, N., Loosemore, M., Kemp, S. & Heron, N., 20 Oct 2019, In : British Journal of Sports Medicine.

Research output: Contribution to journalArticle

Open Access
File
Craniocerebral Trauma
Sports
Amnesia
Unconsciousness
MEDLINE
4 Citations (Scopus)

Spread of Dye Injectate in the Distal Femoral Triangle Versus the Distal Adductor Canal: A Cadaveric Study

Johnston, D. F., Black, N. D., Cowden, R., Turbitt, L. & Taylor, S., 03 Jan 2019, In : Regional Anaesthesia and Pain Management . 44, p. 39-45 7 p.

Research output: Contribution to journalArticle

Quadriceps Muscle
Thigh
Coloring Agents
Injections
Cadaver
8 Citations (Scopus)
64 Downloads (Pure)
Open Access
File
T-Cell Receptor Genes
Validation Studies
Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genetic Recombination

Star polymers with acid-labile diacetal-based cores synthesized by aqueous RAFT polymerization for intracellular DNA delivery

Gibson, T. J., Smyth, P., Semsarilar, M., McCann, A. P., McDaid, W. J., Johnston, M. C., Scott, C. J. & Themistou, E., 05 Jul 2019, In : Polymer Chemistry. 11, 2, p. 344-357 14 p.

Research output: Contribution to journalArticle

Polymerization
Stars
Polymers
DNA
Acids
30 Downloads (Pure)

STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes

Chen, M., Obasanmi, G., Armstrong, D., Lavery, N-J., Kissenpfennig, A., Lois, N. & Xu, H., 08 Jul 2019, In : Journal of neuroinflammation. 16, 1, p. 138

Research output: Contribution to journalArticle

Open Access
File
STAT3 Transcription Factor
Myeloid Cells
Transcriptional Activation
Leukostasis
Diabetic Retinopathy
5 Citations (Scopus)

Statin use after diagnosis is associated with an increased survival in esophageal cancer patients: a Belgian population-based study

Lacroix, O., Couttenier, A., Vaes, E., Cardwell, C. R., De Schutter, H. & Robert, A., 01 Apr 2019, In : Cancer Causes & Control: an international journal of studies of cancer in human populations. 30, 4, p. 385-393 9 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Esophageal Neoplasms
Survival
Confidence Intervals
Mortality

Statin use and longitudinal changes in prostate volume; results from the REDUCE trial

Allott, E. H., Csizmadi, I., Howard, L. E., Muller, R. L., Moreira, D. M., Andriole, G. L., Roehrborn, C. G. & Freedland, S. J., 03 Sep 2019, In : BJU International.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Prostate
Prostatic Neoplasms
Biopsy
Lower Urinary Tract Symptoms
3 Citations (Scopus)
25 Downloads (Pure)

Statin Use and Reduced Risk of Biliary Tract Cancers in the United Kingdom Clinical Practice Research Datalink

Liu, Z., Alsaggaf, R., McGlynn, K. A., Anderson, L. A., Tsai, H-T., Zhu, B., Zhu, Y., Mbulaiteye, S. M., Gadalla, S. M. & Koshiol, J., 05 Jul 2019, In : Gut. 68, p. 1458-1464 7 p.

Research output: Contribution to journalArticle

Open Access
File
Biliary Tract Neoplasms
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Research
Odds Ratio
Confidence Intervals
1 Citation (Scopus)

Statin use and risk of liver cancer: evidence from two population-based studies

Tran, K. T., McMenamin, Ú. C., Coleman, H. G., Cardwell, C., Murchie, P., Iversen, L., Lee, A. J. & Thrift, A. P., 21 May 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver Neoplasms
Population
Medical Informatics
Confidence Intervals
1 Citation (Scopus)

Statin use and survival in patients with gastric cancer in two independent population-based cohorts

Spence, A. D., Busby, J., Hughes, C. M., Johnston, B. T., Coleman, H. G. & Cardwell, C., 01 Apr 2019, In : Pharmacoepidemiology and Drug Safety. 28, 4, p. 460-470 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Stomach Neoplasms
Survival
Population
Confidence Intervals

Statin use is associated with lower risk of PTEN-null and lethal prostate cancer

Allott, E. H., Ebot, E. M., Stopsack, K. H., Gonzalez-Feliciano, A. G., Markt, S. C., Wilson, K. M., Ahearn, T. U., Gerke, T. A., Downer, M. K., Rider, J. R., Freedland, S. J., Lotan, T. L., Kantoff, P. W., Platz, E. A., Loda, M., Stampfer, M. J., Giovannucci, E., Sweeney, C. J., Finn, S. P. & Mucci, L. A., 21 Nov 2019, In : Clinical Cancer Research.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Prostatic Neoplasms
Neoplasms
Prostate
Inflammation
1 Citation (Scopus)

Stereotactic Body Radiation Therapy Boost for Intermediate-Risk Prostate Cancer: A Phase 1 Dose-Escalation Study

Alayed, Y., Loblaw, A., Chu, W., Al-Hanaqta, M., Chiang, A., Jain, S., Chung, H., Vesprini, D., Morton, G., Ravi, A., Davidson, M., Deabreu, A., Mamedov, A., Zhang, L., Erler, D. & Cheung, P., 01 Aug 2019, In : International Journal of Radiation Oncology Biology Physics. 104, 5, p. 1066-1073 8 p.

Research output: Contribution to journalArticle

acceleration (physics)
radiation therapy
Prostatic Neoplasms
Radiotherapy
cancer
102 Downloads (Pure)

Strengthening breast cancer services in Vietnam: a mixed-methods study

Jenkins, C., Ngan, T. T., Ngoc, N. B., Phuong, T. B., Lohfeld, L., Donnelly, M., Minh, H. V. & Murray, L., 30 Jan 2019, In : Global Health Research and Policy . 4, 11 p., 2.

Research output: Contribution to journalArticle

Open Access
File
Vietnam
Health Status
Breast Neoplasms
Health Personnel
Self-Examination
4 Citations (Scopus)
88 Downloads (Pure)

Supporting medication adherence for adults with cystic fibrosis: a randomised feasibility study

Hind, D., Drabble, S. J., Arden, M. A., Mandefield, L., Waterhouse, S., Maguire, C., Cantrill, H., Robinson, L., Beever, D., Scott, A. J., Keating, S., Hutchings, M., Bradley, J., Nightingale, J., Allenby, M. I., Dewar, J., Whelan, P., Ainsworth, J., Walters, S. J., O'Cathain, A. & 1 others, Wildman, M. J., 11 Apr 2019, In : BMC Pulmonary Medicine. 19, 1, p. 77

Research output: Contribution to journalArticle

Open Access
File
Medication Adherence
Feasibility Studies
Cystic Fibrosis
Dry Powder Inhalers
Interviews
1 Citation (Scopus)
Vascular Endothelial Growth Factor A
Retina
Retinal Vessels
Tight Junctions
Claudin-2