School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Article
2019
1 Citation (Scopus)

Statin use and risk of liver cancer: evidence from two population-based studies

Tran, K. T., McMenamin, Ú. C., Coleman, H. G., Cardwell, C., Murchie, P., Iversen, L., Lee, A. J. & Thrift, A. P., 21 May 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver Neoplasms
Population
Medical Informatics
Confidence Intervals
1 Citation (Scopus)

Statin use and survival in patients with gastric cancer in two independent population-based cohorts

Spence, A. D., Busby, J., Hughes, C. M., Johnston, B. T., Coleman, H. G. & Cardwell, C., 01 Apr 2019, In : Pharmacoepidemiology and Drug Safety. 28, 4, p. 460-470 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Stomach Neoplasms
Survival
Population
Confidence Intervals

Statin use is associated with lower risk of PTEN-null and lethal prostate cancer

Allott, E. H., Ebot, E. M., Stopsack, K. H., Gonzalez-Feliciano, A. G., Markt, S. C., Wilson, K. M., Ahearn, T. U., Gerke, T. A., Downer, M. K., Rider, J. R., Freedland, S. J., Lotan, T. L., Kantoff, P. W., Platz, E. A., Loda, M., Stampfer, M. J., Giovannucci, E., Sweeney, C. J., Finn, S. P. & Mucci, L. A., 21 Nov 2019, In : Clinical Cancer Research.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Prostatic Neoplasms
Neoplasms
Prostate
Inflammation
1 Citation (Scopus)

Stereotactic Body Radiation Therapy Boost for Intermediate-Risk Prostate Cancer: A Phase 1 Dose-Escalation Study

Alayed, Y., Loblaw, A., Chu, W., Al-Hanaqta, M., Chiang, A., Jain, S., Chung, H., Vesprini, D., Morton, G., Ravi, A., Davidson, M., Deabreu, A., Mamedov, A., Zhang, L., Erler, D. & Cheung, P., 01 Aug 2019, In : International Journal of Radiation Oncology Biology Physics. 104, 5, p. 1066-1073 8 p.

Research output: Contribution to journalArticle

acceleration (physics)
radiation therapy
Prostatic Neoplasms
Radiotherapy
cancer
104 Downloads (Pure)

Strengthening breast cancer services in Vietnam: a mixed-methods study

Jenkins, C., Ngan, T. T., Ngoc, N. B., Phuong, T. B., Lohfeld, L., Donnelly, M., Minh, H. V. & Murray, L., 30 Jan 2019, In : Global Health Research and Policy . 4, 11 p., 2.

Research output: Contribution to journalArticle

Open Access
File
Vietnam
Health Status
Breast Neoplasms
Health Personnel
Self-Examination
4 Citations (Scopus)
91 Downloads (Pure)

Supporting medication adherence for adults with cystic fibrosis: a randomised feasibility study

Hind, D., Drabble, S. J., Arden, M. A., Mandefield, L., Waterhouse, S., Maguire, C., Cantrill, H., Robinson, L., Beever, D., Scott, A. J., Keating, S., Hutchings, M., Bradley, J., Nightingale, J., Allenby, M. I., Dewar, J., Whelan, P., Ainsworth, J., Walters, S. J., O'Cathain, A. & 1 others, Wildman, M. J., 11 Apr 2019, In : BMC Pulmonary Medicine. 19, 1, p. 77

Research output: Contribution to journalArticle

Open Access
File
Medication Adherence
Feasibility Studies
Cystic Fibrosis
Dry Powder Inhalers
Interviews
1 Citation (Scopus)
Vascular Endothelial Growth Factor A
Retina
Retinal Vessels
Tight Junctions
Claudin-2
24 Downloads (Pure)

Synthetic phosphodiester-linked 4-amino-4-deoxy-L-arabinose derivatives demonstrate ArnT is an inverting aminoarabinosyl transferase

Olagnon, C., Monjaras Feria, J., Grünwald-Gruber, C., Blaukopf, M., Valvano, M. A. & Kosma, P., 24 Jun 2019, In : ChemBioChem.

Research output: Contribution to journalArticle

Open Access
File
Lipid A
Microbial Drug Resistance
Transferases
Lipopolysaccharides
Burkholderia cenocepacia
2 Downloads (Pure)

Systematic endobronchial ultrasound-guided transbronchial needle aspiration improves radiotherapy planning in non-small cell lung cancer

Cole, A. J., Hardcastle, N., Turgeon, G-A., Thomas, R., Irving, L. B., Jennings, B. R., Ball, D., Kron, T., Steinfort, D. P. & Siva, S., 15 Jul 2019, In : Wellcome open research.

Research output: Contribution to journalArticle

Open Access
File
Positron emission tomography
Radiotherapy
Non-Small Cell Lung Carcinoma
Needles
Ultrasonics
3 Citations (Scopus)

Systematic evaluation of Patient-Reported Outcome protocol content and reporting in cancer trials

Kyte, D., Retzer, A., Ahmed, K., Keeley, T., Armes, J., Brown, J. M., Calman, L., Gavin, A., Glaser, A. W., Greenfield, D. M., Lanceley, A., Taylor, R., Velikova, G., Brundage, M., Efficace, F., Mercieca-Bebber, R., King, M. T., Turner, G. & Calvert, M., Nov 2019, In : Journal of the National Cancer Institute. 111, 11, p. 1170-1178 9 p.

Research output: Contribution to journalArticle

Checklist
Publications
Neoplasms
Randomized Controlled Trials
Guidelines
22 Downloads (Pure)

Systematic review of differential methylation in rare ophthalmic diseases

Kerr, K., McAneney, H., Smyth, L., Flanagan, C., Silvestri, J., Nesbitt, M. A., Wooster, C. & McKnight, A., 13 Nov 2019, In : BMJ open ophthalmology.

Research output: Contribution to journalArticle

Open Access
File
Eye Diseases
Rare Diseases
Methylation
Publications
Choroideremia
4 Citations (Scopus)
44 Downloads (Pure)

Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes

Glezeva, N., Moran, B., Collier, P., Moravec, C. S., Phelan, D., Donnellan, E., Russell-Hallinan, A., O'Connor, D. P., Gallagher, W. M., Gallagher, J., McDonald, K., Ledwidge, M., Baugh, J., Das, S. & Watson, C. J., 01 Mar 2019, In : Circulation. Heart failure. 12, 3, p. e005765

Research output: Contribution to journalArticle

Open Access
File
DNA Fingerprinting
DNA Methylation
Epigenomics
Untranslated RNA
Heart Failure
1 Citation (Scopus)

Targeting of Cathepsin S Reduces Cystic Fibrosis-like Lung Disease

Small, D. M., Brown, R. R., Doherty, D. F., Abladey, A., Zhou- Suckow, Z., Delaney, R. J., Kerrigan, L., Dougan, C. M., Borensztajn, K. S., Holsinger, L., Booth, R., Scott, C. J., Lopez Campos, G., Elborn, J. S., Mall, M. A., Weldon, S. & Taggart, C. C., 28 Mar 2019, In : European Respiratory Journal. 53, 3, 1801523.

Research output: Contribution to journalArticle

cathepsin S
Cystic Fibrosis
Lung Diseases
Cats
Epithelial Sodium Channels
56 Downloads (Pure)
Open Access
File
Cystic Fibrosis
Lung Diseases
Peptide Hydrolases
Lung
cathepsin S
12 Downloads (Pure)
Open Access
File
Breast Neoplasms
Growth
Protein Binding
Cell Proliferation
Co-Repressor Proteins
1 Citation (Scopus)

The acetate uptake transporter family motif "NPAPLGL(M/S)" is essential for substrate uptake

Ribas, D., Soares-Silva, I., Vieira, D., Sousa-Silva, M., Sá-Pessoa, J., Azevedo-Silva, J., Viegas, S. C., Arraiano, C. M., Diallinas, G., Paiva, S., Soares, P. & Casal, M., 01 Jan 2019, In : Fungal Genetics and Biology. 122, p. 1-10

Research output: Contribution to journalArticle

Acetates
Membrane Transport Proteins
Methanosarcina
Yarrowia
Acids
67 Downloads (Pure)
Open Access
File
Gastrointestinal Neoplasms
Mouth Neoplasms
Oral Health
Cohort Studies
Prospective Studies
4 Citations (Scopus)

The centrosome protein AKNA regulates neurogenesis via microtubule organization

Camargo Ortega, G., Falk, S., Johansson, P. A., Peyre, E., Broix, L., Sahu, S. K., Hirst, W., Schlichthaerle, T., De Juan Romero, C., Draganova, K., Vinopal, S., Chinnappa, K., Gavranovic, A., Karakaya, T., Steininger, T., Merl-Pham, J., Feederle, R., Shao, W., Shi, S-H., Hauck, S. M. & 10 others, Jungmann, R., Bradke, F., Borrell, V., Geerlof, A., Reber, S., Tiwari, V. K., Huttner, W. B., Wilsch-Bräuninger, M., Nguyen, L. & Götz, M., 07 Mar 2019, In : Nature. 567, 7746, p. 113-117 5 p.

Research output: Contribution to journalArticle

Centrosome
Lateral Ventricles
Neurogenesis
Microtubules
Proteins
24 Downloads (Pure)
Open Access
File
Y Chromosome
Chronic Renal Insufficiency
Chromosomes
X Chromosome
Aneuploidy
21 Downloads (Pure)

The development of a Core Outcome Set for medicines management interventions for people with dementia in primary care

McGrattan, M., Barry, H. E., Ryan, C., Cooper, J. A., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Mar 2019, In : Age and Ageing. 48, 2, p. 260-266

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
307 Downloads (Pure)
Open Access
File
Workplace
Health
Library Science
Diet
Vegetables

The Effect of Aclidinium on Symptoms Including Cough in COPD: A Phase IV, DoubleBlind, Placebo-Controlled, Parallel-Group Study

Smith, J. A., McGarvey, L., Morice, A. H., Birring, S. S., Wedzicha, J. A., Notari, M., Zapata, A., Segarra, R., Seoane, B. & Jarreta, D., 05 Apr 2019, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Food Technology
Feeding Behavior
Food
Northern Ireland
Nutrition Policy
3 Citations (Scopus)

The End user Sensor Tree: An end-user friendly sensor database

Nelis, J. L. D., Tsagkaris, A. S., Zhao, Y., Lou-Franco, J., Nolan, P., Zhou, H., Cao, C., Rafferty, K., Hajslova, J., Elliott, C. T. & Campbell, K., 2019, In : Biosensors and Bioelectronics.

Research output: Contribution to journalArticle

4 Citations (Scopus)
73 Downloads (Pure)

The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies

the European Eye Epidemiology (E3) consortium, 29 Apr 2019, In : Acta Ophthalmologica.

Research output: Contribution to journalArticle

Open Access
File
Optical Coherence Tomography
Epidemiologic Studies
Epidemiology
Retinal Perforations
Retinoschisis
2 Citations (Scopus)
66 Downloads (Pure)

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells

Adane, B., Ye, H., Khan, N., Pei, S., Minhajuddin, M., Stevens, B. M., Jones, C. L., D’Alessandro, A., Reisz, J. A., Zaberezhnyy, V., Gasparetto, M., Ho, T-C., Kelly, K. K., Myers, J. R., Ashton, J. M., Siegenthaler, J., Kume, T., Campbell, E. L., Pollyea, D. A., Becker, M. W. & 1 others, Jordan, C. T., 02 Apr 2019, In : Cell Reports.

Research output: Contribution to journalArticle

Open Access
File
69 Downloads (Pure)

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered Histone H3K9 marks in myeloid leukaemia cells

Clarke, K., Young, C., Liberante, F., McMullin, M., Thompson, A. & Mills, K., 29 May 2019, In : Oncotarget. 10, 37, p. 3462-3471 9 p.

Research output: Contribution to journalArticle

Open Access
File
Histone Code
Histone Deacetylase Inhibitors
Myeloid Leukemia
Myeloid Cells
Myelodysplastic Syndromes
Psychological Adaptation
Curriculum
Hope
Mental Health
coping

The Impact of Adherence to the Traditional Mediterranean Diet and Sex Differences on Global Cognitive Functioning: a Systematic Review and Meta-analysis

Kelly, M. E., Loughrey, D. G., McHugh Power, J., McEvoy, C., Sherrin, C. & Pennie, B., 22 Jul 2019, In : Journal of Cognitive Enhancement. 13 p.

Research output: Contribution to journalArticle

Mediterranean Diet
Sex Characteristics
Meta-Analysis
Cognition
Cohort Studies
1 Citation (Scopus)

The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

the Breast Reconstruction Research Collaborative & on behalf of the iBRA-2 Steering Group, 30 Apr 2019, In : British Journal of Cancer. 120, 9, p. 883-895 13 p.

Research output: Contribution to journalArticle

Mammaplasty
Mastectomy
Therapeutics
Breast Implants
Adjuvant Radiotherapy
58 Downloads (Pure)
Open Access
File
Mouth Rehabilitation
systematic review
Nutrition
Nutritional Status
meta-analysis
42 Downloads (Pure)
Open Access
File
Social Environment
Smoking
imidazole mustard
Northern Ireland
Logistic Models
2 Citations (Scopus)
101 Downloads (Pure)

The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance

Hepburn, A. C., Steele, R. E., Veeratterapillay, R., Wilson, L., Kounatidou, E. E., Barnard, A., Berry, P., Cassidy, J. R., Moad, M., El-Sherif, A., Gaughan, L., Mills, I. G., Robson, C. N. & Heer, R., 11 Feb 2019, In : Oncogene.

Research output: Contribution to journalArticle

Open Access
File
Prostatic Neoplasms
Neoplasms
Stem Cells
RNA Sequence Analysis
Iodide Peroxidase
1 Citation (Scopus)

The intrinsic resistome of Klebsiella pneumoniae

Bernardini, A., Cuesta, T., Tomás, A., Bengoechea, J. A., Martínez, J. L. & Sánchez, M. B., 01 Jan 2019, In : International Journal of Antimicrobial Agents. 53, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

Klebsiella pneumoniae
Bacterial Physiological Phenomena
Genes
Plasmids
Chromosomes, Human, Pair 15
1 Citation (Scopus)
76 Downloads (Pure)

The James Lind Initiative: books, websites and databases to promote critical thinking about treatment claims, 2003 to 2018

Chalmers, I., Atkinson, P., Badenoch, D., Glasziou, P., Austvoll-Dahlgren, A., Oxman, A. & Clarke, M., 04 Feb 2019, In : BMC Research Involvement and Engagement. 5, 14 p., 6.

Research output: Contribution to journalArticle

Open Access
File
Databases
Research
Public Health Practice
Health Services Research
Therapeutics
2 Citations (Scopus)
118 Downloads (Pure)

The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase

Levanova, N., Mattheis, C., Carson, D., To, K-N., Jank, T., Frankel, G., Aktories, K. & Schroeder, G. N., 22 Feb 2019, In : The Journal of biological chemistry.

Research output: Contribution to journalArticle

Open Access
File
Glucosyltransferases
Legionella
Glycosyltransferases
Phosphatidylinositols
Legionella pneumophila
66 Downloads (Pure)
Open Access
File
alcohol
Alcohols
Depression
Growth
adolescent
1 Citation (Scopus)
15 Downloads (Pure)

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination

McMurran, C. E., Guzman de la Fuente, A., Penalva, R., Ben Menachem-Zidon, O., Dombrowski, Y., Falconer, J., Gonzalez, G. A., Zhao, C., Krause, F. N., Young, A. M. H., Griffin, J. L., Jones, C. A., Hollins, C., Heimesaat, M. M., Fitzgerald, D. C. & Franklin, R. J. M., 18 Nov 2019, In : Proceedings of the National Academy of Sciences of the United States of America.

Research output: Contribution to journalArticle

Open Access
File
Microbiota
Demyelinating Diseases
Central Nervous System
Oligodendroglia
Anti-Bacterial Agents
2 Citations (Scopus)
66 Downloads (Pure)

The Necrobiology of Mesenchymal Stromal Cells Affects Therapeutic Efficacy

Weiss, D. J., English, K., Krasnodembskaya, A., Isaza-Correa, J. M., Hawthorne, J. J. & Mahon, B. P., 04 Jun 2019, In : Frontiers in immunology. 10, 12 p., 1228.

Research output: Contribution to journalArticle

Open Access
File
Mesenchymal Stromal Cells
Cell- and Tissue-Based Therapy
Autophagy
Therapeutics
Action Potentials
33 Downloads (Pure)

The neighborhood social environment and physical activity: a systematic scoping review

Kepper, M., Myers, C., Denstel, K., Hunter, R., Guan, W. & Broyles, S., 09 Dec 2019, In : International Journal of Behavioral Nutrition and Physical Activity. 16, 14 p., 124.

Research output: Contribution to journalArticle

Open Access
File
Social Environment
Economics
Crime
Terminology
Population
16 Downloads (Pure)

The NeST (neoadjuvant systemic therapy in breast cancer) study – Protocol for a prospective multi-centre cohort study to assess the current utilization and short-term outcomes of neoadjuvant systemic therapies in breast cancer

Irwin, G. W., Bannon, F., Coles, C. E., Copson, E., Cutress, R. I., Dave, R. V., Grayson, M., Holcombe, C., Irshad, S., O'Brien, C., O'Connell, R. L., Palmieri, C., Shaaban, A. M., Sharma, N., Singh, J., Whitehead, I., Potter, S. & McIntosh, S. A., 11 Nov 2019, In : International Journal of Surgery Protocols. 18, p. 5-11 7 p.

Research output: Contribution to journalArticle

Open Access
File
Neoadjuvant Therapy
Cohort Studies
Breast Neoplasms
Research
Reconstructive Surgical Procedures
96 Downloads (Pure)
Open Access
File
healthy diet
Feeding Behavior
Weaning
eating habits
weaning

The Placental Growth Factor Pathway and its Potential Role in Macular Degenerative Disease

Cunningham, F., Van Bergen, T., Canning, P., Lengyel, I., Feyen, J. H. M. & Stitt, A. W., 04 May 2019, In : Current eye research. 44, 8, p. 813-822

Research output: Contribution to journalArticle

Intercellular Signaling Peptides and Proteins
Macular Degeneration
Vascular Endothelial Growth Factor A
Retina
Geographic Atrophy
1 Citation (Scopus)
33 Downloads (Pure)

The prevention and treatment of glucocorticoid-induced osteopaenia in juvenile rheumatic disease: A randomised double-blind controlled trial

British Society for Paediatric and Adolescent Rheumatology UK, 01 Jul 2019, In : EClinicalMedicine - published by THE LANCET. 12, p. 79-87 9 p.

Research output: Contribution to journalArticle

Open Access
File
Rheumatic Diseases
Glucocorticoids
Placebos
Steroids
Diphosphonates
1 Citation (Scopus)
52 Downloads (Pure)

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors

Thompson, A., Davies, L., Liao, C-T., da Fonseca, D., Griffiths, J., Andrews, R., Jones, A., Clement, M., Brown, G., Humphreys, I., Taylor, P. & Orr, S., 26 Jun 2019, In : PLoS Pathogens. 15, 6, p. e1007850

Research output: Contribution to journalArticle

Open Access
File
C-Type Lectins
Monocytes
Infection
Candida albicans
Knockout Mice
2 Citations (Scopus)

The psychological impact of being on a monitoring pathway for localised prostate cancer: a UK-wide mixed methods study

Matheson, L., Wilding, S., Wagland, R., Nayoan, J., Rivas, C., Downing, A., Wright, P., Brett, J., Kearney, T., Cross, W., Glaser, A. W., Gavin, A. & Watson, E., 10 Jun 2019, In : Psycho-oncology.

Research output: Contribution to journalArticle

Watchful Waiting
Prostatic Neoplasms
Psychology
Interviews
Delivery of Health Care
41 Downloads (Pure)

The Psychological Subtype of Intimate Partner Violence and its Effect on Mental Health: Protocol for A Systematic Review and Meta-Analysis

Dokkedahl, S., Niels Kok, R., Murphy, S., Rønde Kristensen, T., Bech-Hansen, D. & Elklitc, A., 09 Aug 2019, In : Systematic Reviews. 8, 10 p., 198.

Research output: Contribution to journalArticle

Open Access
File
Violence
Meta-Analysis
Mental Health
Psychology
Programming Languages
79 Downloads (Pure)

Therapeutic Targets for the Treatment of Chronic Cough

Roe, N., Lundy, F., Litherland, G. J. & McGarvey, L., 02 May 2019, In : Current Otorhinolaryngology Reports.

Research output: Contribution to journalArticle

Open Access
File
Cough
Therapeutics
Idiopathic Pulmonary Fibrosis
General Practice
Chronic Obstructive Pulmonary Disease
16 Downloads (Pure)

The relationship between oral-health-related quality of life and general health in an elderly population: a cross sectional study

DaMata, C., McKenna, G., Hayes, M. & Allen, F., Mar 2019, In : Gerodontology. 36, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Open Access
File
Oral Health
Cross-Sectional Studies
Quality of Life
Health
Population