School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Review article
2019
Respiratory Syncytial Virus Infections
Chemokines
Epithelium
Cytokines
Infection
3 Citations (Scopus)

Cohort profile: Design and methods in the eye and vision consortium of UK Biobank

UK Biobank Eye and Vision Consortium, 01 Feb 2019, In : BMJ Open. 9, 2, e025077.

Research output: Contribution to journalReview article

Open Access
File
Eye Diseases
Optical Coherence Tomography
Intraocular Pressure
Health
Multimodal Imaging

Curving Cells Inside and Out: Roles of BAR Domain Proteins in Membrane Shaping and Its Cellular Implications

Simunovic, M., Evergren, E., Callan-Jones, A. & Bassereau, P., Oct 2019, In : Annual Review of Cell and Developmental Biology. 35, p. 111-129 19 p.

Research output: Contribution to journalReview article

Membrane Proteins
Membranes
amphiphysin
Protein Domains
Proteins

Developing a disease management program for the improvement of heart failure outcomes: the do’s and the don’ts

Healy, L., Ledwidge, M., Gallagher, J., Watson, C. & McDonald, K., 08 Apr 2019, In : Expert Review of Cardiovascular Therapy. 17, 4, p. 267-273 7 p.

Research output: Contribution to journalReview article

Disease Management
Heart Failure
Heart Diseases
Guidelines
Benchmarking
1 Citation (Scopus)
Open Access
File
Alzheimer Disease
Cognition
Diet
Inflammation
Mediterranean Diet
1 Citation (Scopus)

Emerging drugs for treating the acute respiratory distress syndrome

Shaw, T. D., McAuley, D. F. & O'Kane, C. M., 18 Mar 2019, In : Expert opinion on emerging drugs. 24, 1, p. 29-41 13 p.

Research output: Contribution to journalReview article

Adult Respiratory Distress Syndrome
Pharmaceutical Preparations
Clinical Trials
Pharmacology
Expert Testimony
1 Citation (Scopus)

Evolution of the Supermodel: Progress in Modelling Radiotherapy Response in Mice.

Butterworth, K., 11 Mar 2019, In : Clinical oncology (Royal College of Radiologists (Great Britain)). doi: 10.1016/j.clon.2019.02.008.

Research output: Contribution to journalReview article

Radiotherapy
Radiobiology
Neoplasms
Research
Carcinogenesis
Signs and Symptoms
Referral and Consultation
Vaccination
Infection
Meningitis
1 Citation (Scopus)
Open Access
File
Kidney Diseases
Genetic Predisposition to Disease
Chronic Renal Insufficiency
Genome-Wide Association Study
Telomere

Healthcare professional perceived barriers and facilitators to discussing sexual wellbeing with patients after diagnosis of chronic illness: A mixed-methods evidence synthesis

O'Connor, S. R., Connaghan, J., Maguire, R., Kotronoulas, G., Flannagan, C., Jain, S., Brady, N. & McCaughan, E., May 2019, In : Patient Education and Counseling. 102, 5, p. 850-863 14 p.

Research output: Contribution to journalReview article

Chronic Disease
Delivery of Health Care
Social Perception
Reproductive Health
Databases

How can clinical research improve European health outcomes in cancer?

Selby, P., Liu, L., Downing, A., Banks, I., Wilson, R., Stephens, R., Meunier, F., Rochon, J., Morris, E., Seymour, M., Gregory, W., Lawler, M. & Boaz, A., 01 Jun 2019, In : Journal of Cancer Policy. 20, 6 p., 100182.

Research output: Contribution to journalReview article

Health
Research
Neoplasms
Patient Participation
Policy Making
1 Citation (Scopus)

Impact of single nucleotide polymorphisms on the efficacy and toxicity of egfr tyrosine kinase inhibitors in advanced non-small cell lung cancer patients.

Perez-Ramirez, C., Cañadas-Garre, M., Molina, M. A., Cabeza Barrera, J. & Faus Dader, M. J., 09 Apr 2019, In : Mutation research-Reviews in mutation research.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Single Nucleotide Polymorphism
Survival
Cytochrome P-450 Enzyme System

Integrating Small Animal Irradiators with Functional Imaging for Advanced Preclinical Radiotherapy Research.

Butterworth, K., Ghita, M., Brown, K., Kelada, O. & Graves, E. E., 02 Feb 2019, In : Cancers. 11, 2

Research output: Contribution to journalReview article

Open Access
File
Radiotherapy
Biological Models
Radiation Oncology
Molecular Imaging
Translational Medical Research

Interventions to improve psychosocial well-being in female brca-mutation carriers following risk-reducing surgery

Jeffers, L., Reid, J., Fitzsimons, D., Morrison, P. J. & Dempster, M., 09 Oct 2019, In : Cochrane Database of Systematic Reviews. 2019, 10, CD012894.

Research output: Contribution to journalReview article

Open Access
Mutation
Quality of Life
Mindfulness
Confidence Intervals
Ovariectomy
1 Citation (Scopus)

Meat thermometer usage amongst European and North American consumers: A scoping review

Elshahat, S., Woodside, J. V. & McKinley, M. C., 01 Dec 2019, In : Food Control. 106, 12 p., 106692.

Research output: Contribution to journalReview article

Thermometers
thermometers
Meat
meat
Cooking
2 Citations (Scopus)

Mechanistic Modelling of Radiation Responses

McMahon, S. J. & Prise, K. M., 10 Feb 2019, In : Cancers. 11, 2, 23 p., 205.

Research output: Contribution to journalReview article

Open Access
File
Radiobiology
Radiation
Cell- and Tissue-Based Therapy
Linear Models
Radiotherapy

Oligodendrocytes in Development, Myelin Generation and Beyond

Kuhn, S., Gritti, L., Crooks, D. & Dombrowski, Y., 12 Nov 2019, In : Cells. 8, 11, 23 p., 1424.

Research output: Contribution to journalReview article

Open Access
File
Oligodendroglia
Myelin Sheath
Stem Cells
Central Nervous System
Pathology
1 Citation (Scopus)

Oral hygiene interventions for people with intellectual disabilities

Waldron, C., Nunn, J., Mac Giolla Phadraig, C., Comiskey, C., Guerin, S., van Harten, M. T., Donnelly-Swift, E. & Clarke, M. J., 31 May 2019, In : The Cochrane database of systematic reviews. 5, 202 p., CD012628.

Research output: Contribution to journalReview article

Open Access
Oral Hygiene
Disabled Persons
Intellectual Disability
Randomized Controlled Trials
Inflammation

Pulpotomy for mature carious teeth with symptoms of irreversible pulpitis: A systematic review

Cushley, S., Duncan, H. F., Lappin, M., Tomson, P. L., Lundy, F. T., Cooper, P., Clarke, M. & El Karim, I. A., 20 Jun 2019, In : Journal of Dentistry.

Research output: Contribution to journalReview article

Pulpotomy
Pulpitis
Tooth
Signs and Symptoms
Dental Pulp Cavity
3 Citations (Scopus)

Respiratory viral infection: A potential “missing link” in the pathogenesis of COPD

Linden, D., Guo-Parke, H., Coyle, P. V., Fairley, D., McAuley, D. F., Taggart, C. C. & Kidney, J., 31 Mar 2019, In : European Respiratory Review. 28, 151, 14 p., 180063.

Research output: Contribution to journalReview article

Open Access
File
Virus Diseases
Respiratory Tract Infections
Chronic Obstructive Pulmonary Disease
Disease Progression
Molecular Diagnostic Techniques

Souvenaid in the management of mild cognitive impairment: An expert consensus opinion

Cummings, J., Passmore, P., McGuinness, B., Mok, V., Chen, C., Engelborghs, S., Woodward, M., Manzano, S., Garcia-Ribas, G., Cappa, S., Bertolucci, P. & Chu, L. W., 17 Aug 2019, In : Alzheimer's Research and Therapy. 11, 1, 73.

Research output: Contribution to journalReview article

Open Access
File
Expert Testimony
Consensus
Life Style
Early Diagnosis
Alzheimer Disease

The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer

Amirkhah, R., Naderi-Meshkin, H., Shah, J. S., Dunne, P. D. & Schmitz, U., 19 Aug 2019, In : Cells. 8, 8

Research output: Contribution to journalReview article

Open Access
File
Untranslated RNA
Alternative Splicing
Epigenomics
Colorectal Neoplasms
Histone Code
1 Citation (Scopus)

Therapies for Type 1 Diabetes: Current Scenario and Future Perspectives

Pathak, V., Pathak, N. M., O’Neill, C. L., Guduric-Fuchs, J. & Medina, R. J., 03 May 2019, In : Clinical Medicine Insights: Endocrinology and Diabetes. 12, 13 p.

Research output: Contribution to journalReview article

Open Access
File
Type 1 Diabetes Mellitus
Islets of Langerhans Transplantation
Islets of Langerhans
Diabetes Complications
Insulin

The relevance of TP53 for CLL diagnostics

Catherwood, M. A., Gonzalez de Castro, D., Donaldson, D., Clifford, R., Mills, K. I. & Thornton, P. D., 16 Apr 2019, In : Journal of Clinical Pathology. 72, p. 343-346 4 p.

Research output: Contribution to journalReview article

Open Access
Mutation
Tumor Suppressor Protein p53
B-Cell Chronic Lymphocytic Leukemia
Therapeutics
Neoplasms
4 Citations (Scopus)

The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases

Van Bergen, T., Etienne, I., Cunningham, F., Moons, L., Schlingemann, R. O., Feyen, J. H. M. & Stitt, A. W., 01 Mar 2019, In : Progress in Retinal and Eye Research. 69, p. 116-136 21 p.

Research output: Contribution to journalReview article

Retinal Diseases
Retinal Vessels
Growth Factor Receptors
Vascular Diseases
Intercellular Signaling Peptides and Proteins
2 Citations (Scopus)

Vitamin E and Alzheimer’s disease: What do we know so far?

Browne, D., McGuinness, B., Woodside, J. V. & McKay, G. J., 18 Jul 2019, In : Clinical interventions in aging. 14, p. 1303-1317 15 p.

Research output: Contribution to journalReview article

Open Access
File
Vitamin E
Alzheimer Disease
Protein Isoforms
Tocotrienols
Tocopherols

Zinc Nutrition and Inflammation in the Aging Retina

Gilbert, R., Peto, T., Lengyel, I. & Emri, E., 30 May 2019, In : Molecular Nutrition & Food Research.

Research output: Contribution to journalReview article

retina
Retina
Zinc
inflammation
zinc
2018
2 Citations (Scopus)

Advance care planning with patients who have end-stage kidney disease a systematic realist review

O'Halloran, P., Noble, H., Norwood, K., Maxwell, P., Shields, J., Fogarty, D., Murtagh, F., Morton, R. & Brazil, K., 16 Jul 2018, In : Journal of Pain and Symptom Management.

Research output: Contribution to journalReview article

Open Access
File
Advance Care Planning
Chronic Kidney Failure
Delivery of Health Care
Advance Directives
Life Expectancy
173 Citations (Scopus)

After asthma: redefining airways diseases

Pavord, I. D., Beasley, R., Agusti, A., Anderson, G. P., Bel, E., Brusselle, G., Cullinan, P., Custovic, A., Ducharme, F. M., Fahy, J. V., Frey, U., Gibson, P., Heaney, L. G., Holt, P. G., Humbert, M., Lloyd, C. M., Marks, G., Martinez, F. D., Sly, P. D., von Mutius, E. & 3 othersWenzel, S., Zar, H. J. & Bush, A., 27 Jan 2018, In : Lancet. 391, 10118, p. 350-400 51 p.

Research output: Contribution to journalReview article

57 Citations (Scopus)

Age and Age-related Diseases: Role of Inflammation Triggers and Cytokines

Rea, I. M., Gibson, D. S., McGilligan, V., McNerlan, S. E. & Alexander, H. D., 09 Apr 2018, In : Frontiers in immunology. p. 1-28 586.

Research output: Contribution to journalReview article

Open Access
File
Cytokines
Inflammation
Rheumatoid Arthritis
Inflammasomes
Autophagy
1 Citation (Scopus)
Open Access
File
Non-Small Cell Lung Carcinoma
Prescriptions
Radiotherapy
Standard of Care
Publications
6 Citations (Scopus)

Barriers to and enablers of diabetic retinopathy screening attendance: a systematic review of published and grey literature

Graham-Rowe, E., Lorencatto, F., Lawrenson, J. G., Burr, J. M., Grimshaw, J. M., Ivers, N. M., Presseau, J., Vale, L., Peto, T., Bunce, C. & J Francis, J., 06 Jun 2018, In : Diabetic Medicine.

Research output: Contribution to journalReview article

Open Access
File
Literature
Diabetic Retinopathy
MEDLINE
Type 2 Diabetes Mellitus
Libraries
3 Citations (Scopus)

Bromodomain-containing proteins in prostate cancer

Urbanucci, A. & Mills, I. G., 15 Feb 2018, In : Molecular and Cellular Endocrinology. 462, Part A

Research output: Contribution to journalReview article

Androgen Receptors
Prostatic Neoplasms
Pharmaceutical Preparations
Chromatin
Proteins
166 Citations (Scopus)

Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018

Ferlay, J., Colombet, M., Soerjomataram, I., Dyba, T., Randi, G., Bettio, M., Gavin, A., Visser, O. & Bray, F., Nov 2018, In : European journal of cancer (Oxford, England : 1990). 103, p. 356-387 32 p.

Research output: Contribution to journalReview article

Mortality
Incidence
Neoplasms
Lung Neoplasms
Breast Neoplasms
3 Citations (Scopus)

Cardiovascular risk in renal transplant recipients

Devine, P. A., Courtney, A. E. & Maxwell, A. P., 07 Nov 2018, In : Journal of Nephrology. p. 1-11

Research output: Contribution to journalReview article

Open Access
File
Kidney
Transplants
Immunosuppression
Chronic Kidney Failure
Organ Transplantation
8 Citations (Scopus)

Citrus fruits intake and oral cancer risk: A systematic review and meta-analysis

Cirmi, S., Navarra, M., Woodside, J. V. & Cantwell, M. M., Jul 2018, In : Pharmacological Research. 133, p. 187-194

Research output: Contribution to journalReview article

Open Access
File
Citrus
Mouth Neoplasms
Meta-Analysis
Pharyngeal Neoplasms
Mouth
18 Citations (Scopus)

Consensus on molecular imaging and theranostics in prostate cancer

Fanti, S., Minozzi, S., Antoch, G., Banks, I., Briganti, A., Carrio, I., Chiti, A., Clarke, N., Eiber, M., De Bono, J., Fizazi, K., Gillessen, S., Gledhill, S., Haberkorn, U., Herrmann, K., Hicks, R. J., Lecouvet, F., Montironi, R., Ost, P., O'Sullivan, J. M. & 11 othersPadhani, A. R., Schalken, J. A., Scher, H. I., Tombal, B., van Moorselaar, R. J. A., Van Poppel, H., Vargas, H. A., Walz, J., Weber, W. A., Wester, H-J. & Oyen, W. J. G., 01 Dec 2018, In : Lancet Oncology. 19, 12, p. e696-e708 13 p.

Research output: Contribution to journalReview article

Molecular Imaging
Prostatic Neoplasms
Consensus
Radiopharmaceuticals
Bone and Bones
1 Citation (Scopus)
Open Access
File
integrity
profession
health
evidence
education

Control and dysregulation of redox signaling in the gastrointestinal tract

Campbell, E. & Colgan, S. P., 15 Aug 2018, (Accepted) In : Nature Reviews Gastroenterology & Hepatology.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)

Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer

Lawler, M., Alsina, D., Adams, R. A., Anderson, A. S., Brown, G., Fearnhead, N. S., Fenwick, S. W., Halloran, S. P., Hochhauser, D., Hull, M. A., Koelzer, V. H., McNair, A. G. K., Monahan, K. J., Näthke, I., Norton, C., Novelli, M. R., Steele, R. J. C., Thomas, A. L., Wilde, L. M., Wilson, R. H. & 2 othersTomlinson, I. & Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative, 01 Jan 2018, In : Gut. 67, 1, p. 179-193 15 p.

Research output: Contribution to journalReview article

Open Access
File
Colorectal Neoplasms
Research
Communication
Pathology
Tumor Microenvironment
24 Citations (Scopus)

Delivering modern, high-quality, affordable pathology and laboratory medicine to low-income and middle-income countries: a call to action

Horton, S., Sullivan, R., Flanigan, J., Fleming, K. A., Kuti, M. A., Looi, L. M., Pai, S. A. & Lawler, M., May 2018, In : Lancet. 391, 10133, p. 1953-1964

Research output: Contribution to journalReview article

Medicine
Pathology
Conservation of Natural Resources
Health
Universal Coverage
5 Citations (Scopus)

Diabetes and complications of the heart in Sub-Saharan Africa: An urgent need for improved awareness, diagnostics and management

Glezeva, N., Chisale, M., McDonald, K., Ledwidge, M., Gallagher, J. & Watson, C. J., 01 Mar 2018, In : Diabetes Research and Clinical Practice. 137, p. 10-19

Research output: Contribution to journalReview article

Open Access
File
Africa South of the Sahara
Diabetes Complications
Type 2 Diabetes Mellitus
Heart Failure
Community Health Services
2 Citations (Scopus)

Different lasers and techniques for proliferative diabetic retinopathy

Moutray, T., Evans, J. R., Lois, N., Armstrong, D. J., Peto, T. & Azuara-Blanco, A., 15 Mar 2018, In : The Cochrane database of systematic reviews. 3, p. CD012314

Research output: Contribution to journalReview article

Open Access
File
Light Coagulation
Diabetic Retinopathy
Lasers
Argon
Odds Ratio
9 Citations (Scopus)

Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future

International ECMO Network (ECMONet), Nov 2018, In : The Lancet Respiratory Medicine. 6, 11, p. 874-884 11 p.

Research output: Contribution to journalReview article

Open Access
File
Artificial Respiration
Carbon Dioxide
Respiratory Insufficiency
Research
Therapeutics
7 Citations (Scopus)

FLIP as a therapeutic target in cancer

Humphreys, L., Espona-Fiedler, M. & Longley, D. B., Nov 2018, In : The FEBS Journal. 285, 22, p. 4104-4123 20 p.

Research output: Contribution to journalReview article

Cell death
Cell Death
Caspase 8
CASP8 and FADD-Like Apoptosis Regulating Protein
Neoplasms
2 Citations (Scopus)
Open Access
File
Biomarkers
Chronic Renal Insufficiency
Kidney Diseases
Epigenomics
Creatinine

Heart Failure in Sub-Saharan Africa

Gallagher, J., McDonald, K., Ledwidge, M. & Watson, C., 01 May 2018, In : Cardiac Failure Review. 4, 1, p. 21-24 4 p.

Research output: Contribution to journalReview article

Africa South of the Sahara
Heart Failure
Endomyocardial Fibrosis
Professional Competence
Rheumatic Heart Disease
2 Citations (Scopus)

HER2 testing of gastro-oesophageal adenocarcinoma: a commentary and guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Committee

Wong, N. A. C. S., Amary, F., Butler, R., Byers, R., Gonzalez, D., Haynes, H. R., Ilyas, M., Salto-Tellez, M. & Taniere, P., 08 Feb 2018, In : Journal of Clinical Pathology.

Research output: Contribution to journalReview article

Molecular Pathology
Adenocarcinoma
Guidelines
National Health Programs
Biological Products
30 Citations (Scopus)

Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions

Sayed, S., Cherniak, W., Lawler, M., Tan, S. Y., El Sadr, W., Wolf, N., Silkensen, S., Brand, N., Looi, L. M., Pai, S. A., Wilson, M. L., Milner, D., Flanigan, J. & Fleming, K. A., 14 Mar 2018, In : Lancet. 391, 10133, p. 1939-1952

Research output: Contribution to journalReview article

Medicine
Pathology
Telepathology
Clinical Laboratory Information Systems
Public-Private Sector Partnerships
6 Citations (Scopus)

Interventions to increase attendance for diabetic retinopathy screening

Lawrenson, J. G., Graham-Rowe, E., Lorencatto, F., Burr, J., Bunce, C., Francis, J. J., Aluko, P., Rice, S., Vale, L., Peto, T., Presseau, J., Ivers, N. & Grimshaw, J. M., 15 Jan 2018, In : The Cochrane database of systematic reviews. 1, p. CD012054

Research output: Contribution to journalReview article

Open Access
File
Diabetic Retinopathy
Quality Improvement
Confidence Intervals
Delivery of Health Care
Cost-Benefit Analysis