School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Review article
1995
3 Citations (Scopus)

Pharmacokinetics and pharmacodynamics of r-HuEPO

Maxwell, A. P. & Lappin, T. R. J., 01 Jan 1995, In : Erythropoiesis: New Dimensions in the Treatment of Anaemia. 6, 2, p. 46-53 8 p.

Research output: Contribution to journalReview article

Erythropoietin
Pharmacokinetics
Chronic Kidney Failure
Plasma Volume
Intravenous Injections
1999
353 Citations (Scopus)

Serial killers: ordering caspase activation events in apoptosis

Slee, E. A., Adrain, C. & Martin, S. J., Nov 1999, In : Cell Death and Differentiation. 6, 11, p. 1067-74 8 p.

Research output: Contribution to journalReview article

Caspases
Apoptosis
Effector Caspases
Caspase 3
Peptide Hydrolases
2002
112 Citations (Scopus)

Evaluation of mechanical arterial properties: clinical, experimental and therapeutic aspects

McVeigh, G., Hamilton, P. & Morgan, D. R., 2002, In : Clinical science (London, England : 1979). 102, 1, p. 51-67 17 p.

Research output: Contribution to journalReview article

2003
78 Citations (Scopus)

Portrait of a killer: the mitochondrial apoptosome emerges from the shadows

Hill, M. M., Adrain, C. & Martin, S. J., Feb 2003, In : Molecular interventions. 3, 1, p. 19-26 8 p.

Research output: Contribution to journalReview article

Apoptosomes
Apoptosis
Caspases
Physiological Phenomena
Cysteine Proteases
2004
17 Citations (Scopus)

A higher order of silence

Tielenius Kruythoff-Mohd Sarip, A. & Verrijzer, C. P., 26 Nov 2004, In : Science. 306, 5701, p. 1484-1485 2 p.

Research output: Contribution to journalReview article

64 Citations (Scopus)

Procedure guidelines for radionuclide myocardial perfusion imaging

Anagnostopoulos, C., Harbinson, M., Kelion, A., Kundley, K., Loong, C. Y., Notghi, A., Reyes, E., Tindale, W. & Underwood, S. R., 01 Jan 2004, In : Heart. 90, SUPPL. 1, p. i1-i10

Research output: Contribution to journalReview article

677 Citations (Scopus)

The epidemiology of age-related macular degeneration

Klein, R., Peto, T., Bird, A. & Vannewkirk, M. R., Mar 2004, In : American Journal of Ophthalmology. 137, 3, p. 486-95 10 p.

Research output: Contribution to journalReview article

Macular Degeneration
Epidemiology
Geographic Atrophy
Iceland
Information Dissemination
2005
67 Citations (Scopus)

A theory of maternal engagement with public health nurses and family visitors

Jack, S. M., Dicenso, A. & Lohfeld, L., Jan 2005, In : Journal of Advanced Nursing. 49, 2, p. 182-90 9 p.

Research output: Contribution to journalReview article

Public Health Nurses
Mothers
Fear
House Calls
Aptitude
819 Citations (Scopus)

Molecular mechanisms of drug resistance

Longley, D. B. & Johnston, P. G., 2005, In : Journal of Pathology. 205, 2, p. 275-292 18 p.

Research output: Contribution to journalReview article

Drug Resistance
Pharmaceutical Preparations
Drug Therapy
Neoplasms
Therapeutics
2007
5 Citations (Scopus)

Exploring alternative individualized treatment strategies in colorectal cancer

Wilson, P. M., Ladner, R. D. & Lenz, H-J., Dec 2007, In : Clinical colorectal cancer. 7 Suppl 1, p. S28-36

Research output: Contribution to journalReview article

Colorectal Neoplasms
oxaliplatin
irinotecan
Fluorouracil
Therapeutics
2008

A cardiologist view on vascular disease in diabetes

Lockhart, C., Hamilton, P., McVeigh, K. & McVeigh, G., 2008, In : Diabetes, Obesity and Metabolism. 10, p. 279-292

Research output: Contribution to journalReview article

4 Downloads (Pure)

Insights into Langerhans Cell Function from LC Deficient Mice

Kaplan, D. H., Kissenpfennig, A. & Clausen, B. E., Sep 2008, In : European Journal of Immunology. 38(9), p. 2369-2376 8 p.

Research output: Contribution to journalReview article

Langerhans Cells
52 Citations (Scopus)

Role of the innate immune system in autoimmune inflammatory demyelination

O'Brien, K., Fitzgerald, D., Naiken, K., Alugupalli, K. R., Rostami, A. M. & Gran, B., May 2008, In : Current medicinal chemistry. 15(11), 11, p. 1105-1115 11 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

The morphology of the optic nerve head in the Singaporean Chinese population (the Tanjong Pagar study): part 1--Optic nerve head morphology

Bourne, R. R. A., Foster, P. J., Bunce, C., Peto, T., Hitchings, R. A., Khaw, P. T., Seah, S. K. L. & Garway-Heath, D. F., Mar 2008, In : British Journal of Ophthalmology. 92, 3, p. 303-9 7 p.

Research output: Contribution to journalReview article

Optic Disk
Population
Refractive Errors
Singapore
Anterior Chamber
2009

Co-transmission in the autonomic nervous system. (Review)

Teschermaker, A. & Johnson, C., 2009, In : Experimental Physiology. 94, p. 18-19

Research output: Contribution to journalReview article

48 Citations (Scopus)

End-organ dysfunction and cardiovascular outcomes: the role of the microcirculation.

Lockhart, C. J., Hamilton, P. K., Quinn, C. E. & McVeigh, G., Feb 2009, In : Clinical science (London, England : 1979). 116, 3, p. 175-190 16 p.

Research output: Contribution to journalReview article

72 Citations (Scopus)

Fetal cardiac effects of maternal hyperglycemia during pregnancy

Corrigan, N., Brazil, D. P. & McAuliffe, F., 01 Jun 2009, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 85, 6, p. 523-530 8 p.

Research output: Contribution to journalReview article

Hyperglycemia
Mothers
Teratogenesis
Pregnancy
Type 1 Diabetes Mellitus
8 Citations (Scopus)

Therapeutic potential of IL-27 in Multiple Sclerosis?

Fitzgerald, D. & Rostami, A., Feb 2009, In : Expert Opinion on Biological Therapy. 9(2), 2, p. 149-160 12 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

The role of ezetimibe in the management of patients with atherosclerosis

Hamilton, P., 2009, In : Coronary artery disease. 20, p. 169-174

Research output: Contribution to journalReview article

2010
24 Citations (Scopus)

Antiproteases as therapeutics to target inflammation in cystic fibrosis.

Quinn, D., Weldon, S. & Taggart, C., Apr 2010, In : The open respiratory medicine journal. 4, p. 20-31

Research output: Contribution to journalReview article

Protease Inhibitors
Cystic Fibrosis
Inflammation
Peptide Hydrolases
Infection

Diverse and opposing roles of IL-27 in immunity

Fonseca-Kelly, Z., And, A. R. & Fitzgerald, D., 2010, In : Open Autoimmunity Journal. in press, p. 000-000 1 p.

Research output: Contribution to journalReview article

2011
6 Citations (Scopus)

Bronchiolitis

Bourke, T. & Shields, M., 11 Apr 2011, In : Clinical Evidence. 2011

Research output: Contribution to journalReview article

Bronchiolitis
montelukast
Epinephrine
Immunoglobulins
Eye Protective Devices
27 Citations (Scopus)

Elder abuse and oppression: voices of marginalized elders

Walsh, C. A., Olson, J. L., Ploeg, J., Lohfeld, L. & MacMillan, H. L., Jan 2011, In : Journal of Elder Abuse and Neglect. 23, 1, p. 17-42 26 p.

Research output: Contribution to journalReview article

Elder Abuse
oppression
abuse
Homophobia
Ageism
18 Citations (Scopus)

Energy intake and response to infection with influenza

Gardner, E. M., Beli, E., Clinthorne, J. F. & Duriancik, D. M., 21 Aug 2011, In : Annual review of nutrition. 31, p. 353-67 15 p.

Research output: Contribution to journalReview article

Energy Intake
Human Influenza
Obesity
Infection
Diet
17 Citations (Scopus)

Proteomics in the microbial sciences

Graham, C., McMullan, G. & Graham, R. L. J., 01 Jan 2011, In : Bioengineered Bugs. 2, 1, p. 1-14 14 p.

Research output: Contribution to journalReview article

Proteomics
Mass spectrometry
Mass Spectrometry
Mass spectrometers
Post Translational Protein Processing
2012
23 Citations (Scopus)
Human Mammary Glands
Breast
Stem Cells
Breast Neoplasms
Cell Differentiation
13 Citations (Scopus)

Development of a disease-specific quality-of-life questionnaire for anterior and central skull base pathology--the skull base inventory

de Almeida, J. R., Vescan, A. D., Gullane, P. J., Gentili, F., Lee, J. M., Lohfeld, L., Ringash, J., Thoma, A. & Witterick, I. J., Sep 2012, In : The Laryngoscope. 122, 9, p. 1933-42 10 p.

Research output: Contribution to journalReview article

Skull Base
Focus Groups
Quality of Life
Pathology
Equipment and Supplies
11 Citations (Scopus)

Men's attitudes towards chlamydia screening: a narrative review

Balfe, M., Brugha, R., O'Connell, E., Vaughan, D. & O'Donovan, D., May 2012, In : Health. 9, 2, p. 120-30 11 p.

Research output: Contribution to journalReview article

Chlamydia
narrative
Infection
Men's Health
Masculinity
6 Citations (Scopus)

Recent advances in the application of antibodies as therapeutics.

Burden, R. E., Caswell, J., Fay, F. & Scott, C. J., Jan 2012, In : FUTURE MEDICINAL CHEMISTRY. 4, 1, p. 73-86 14 p.

Research output: Contribution to journalReview article

Antibodies
Therapeutics
Pharmaceutical Preparations
Neoplasms
6 Citations (Scopus)

Chemotherapy causes cancer! A case report of therapy related acute myeloid leukaemia in early stage breast cancer

Aidan, J. C., Priddee, N. R. & McAleer, J. J., May 2013, In : The Ulster Medical Journal. 82, 2, p. 97-9 3 p.

Research output: Contribution to journalReview article

Acute Myeloid Leukemia
Breast Neoplasms
Drug Therapy
Neoplasms
Adjuvant Radiotherapy
66 Citations (Scopus)

Diabetic retinopathy: pathogenesis, clinical grading, management and future developments

Heng, L. Z., Comyn, O., Peto, T., Tadros, C., Ng, E., Sivaprasad, S. & Hykin, P. G., Jun 2013, In : Diabetic Medicine. 30, 6, p. 640-50 11 p.

Research output: Contribution to journalReview article

Diabetic Retinopathy
Macular Edema
Vascular Endothelial Growth Factor A
Light Coagulation
Vision Disorders
110 Citations (Scopus)

Macular telangiectasia type 2

Charbel Issa, P., Gillies, M. C., Chew, E. Y., Bird, A. C., Heeren, T. F. C., Peto, T., Holz, F. G. & Scholl, H. P. N., May 2013, In : Progress in Retinal and Eye Research. 34, p. 49-77 29 p.

Research output: Contribution to journalReview article

Telangiectasis
Atrophy
Retina
Fluorescein Angiography
Optical Coherence Tomography

Management of hyperkalaemia

Maxwell, A., Linden, K., O'Donnell, S., Hamilton, P. & McVeigh, G., 2013, In : Journal of the Royal College of Physicians of Edinburgh. 43, p. 246-251

Research output: Contribution to journalReview article

13 Citations (Scopus)

Mechanistic targets and phytochemical strategies for breaking the obesity-cancer link

Ford, N. A., Lashinger, L. M., Allott, E. H. & Hursting, S. D., 2013, In : Frontiers in oncology. 3, p. 209

Research output: Contribution to journalReview article

Phytochemicals
Obesity
Neoplasms
Tumor Microenvironment
Intercellular Signaling Peptides and Proteins
13 Citations (Scopus)

Non-adherence in difficult asthma and advances in detection

Lindsay, J. T. & Heaney, L. G., Dec 2013, In : Expert review of respiratory medicine. 7, 6, p. 607-14 8 p.

Research output: Contribution to journalReview article

Asthma
Hospitalization
Anti-Inflammatory Agents
Therapeutics
12 Citations (Scopus)

Quality of life instruments for skull base pathology: systematic review and methodologic appraisal

de Almeida, J. R., Witterick, I. J., Gullane, P. J., Gentili, F., Lohfeld, L., Ringash, J., Thoma, A. & Vescan, A. D., Sep 2013, In : Head & neck. 35, 9, p. 1221-31 11 p.

Research output: Contribution to journalReview article

Skull Base
Quality of Life
Pathology
Psychometrics
Bibliography
62 Citations (Scopus)

The relationship between nutrition and prostate cancer: is more always better?

Masko, E. M., Allott, E. H. & Freedland, S. J., May 2013, In : European Urology. 63, 5, p. 810-20 11 p.

Research output: Contribution to journalReview article

Prostatic Neoplasms
Diet
Food
Micronutrients
Phytochemicals
2014
14 Citations (Scopus)

Biological therapies in the acute respiratory distress syndrome

Boyle, A. J., McNamee, J. J. & McAuley, D. F., Jul 2014, In : Expert Opinion on Biological Therapy. 14, 7, p. 969-81

Research output: Contribution to journalReview article

Gene therapy
Biological Therapy
Adult Respiratory Distress Syndrome
Coagulation
Stem cells
31 Citations (Scopus)

Motion Management for Radical Radiotherapy in Non-small Cell Lung Cancer

Cole, A. J., Hanna, G. G., Jain, S. & O'Sullivan, J., Feb 2014, In : Clinical oncology (Royal College of Radiologists (Great Britain)). 26, 2, p. 67-80 14 p.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Radiotherapy
Neoplasms
Image-Guided Radiotherapy
Lung
2015
59 Citations (Scopus)
318 Downloads (Pure)

Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis

Dark, P., Blackwood, B., Gates, S., McAuley, D., Perkins, G. D., McMullan, R., Wilson, C., Graham, D., Timms, K. & Warhurst, G., Jan 2015, In : Intensive Care Medicine. 41, 1, p. 21-33 13 p.

Research output: Contribution to journalReview article

Open Access
File
Meta-Analysis
Sepsis
Sensitivity and Specificity
Computer Systems
Routine Diagnostic Tests

Ageing and the immune system: focus on macrophages

Linehan, E. & Fitzgerald, D. C., 2015, In : European Journal of Microbiology and Immunology. 5, 1, p. 14-24 11 p.

Research output: Contribution to journalReview article

Immune System
Macrophages
Population
Toll-Like Receptors
Health
49 Citations (Scopus)

A review of recent advances in optical fibre sensors for in vivo dosimetry during radiotherapy

O'Keeffe, S., McCarthy, D., Woulfe, P., Grattan, M. W. D., Hounsell, A. R., Sporea, D., Mihai, L., Vata, I., Leen, G. & Lewis, E., 01 Jun 2015, In : British Journal of Radiology. 88, 1050, 20140702.

Research output: Contribution to journalReview article

Optical Fibers
Radiotherapy
Electromagnetic Phenomena
Brachytherapy
Needles
48 Citations (Scopus)

BRCA1, a 'complex' protein involved in the maintenance of genomic stability

Savage, K. I. & Harkin, D. P., Feb 2015, In : The FEBS Journal. 282, 4, p. 630-646 17 p.

Research output: Contribution to journalReview article

Genomic Instability
Tumors
Maintenance
Cell Cycle Checkpoints
DNA Repair
6 Citations (Scopus)
121 Downloads (Pure)

Genes and life-style factors in BELFAST nonagenarians: Nature, Nurture and Narrative

Rea, J. N. M., Carvalho, A., McNerlan, S. E., Alexander, H. D. & Rea, I. M., Oct 2015, In : Biogerontology. 16, 5, p. 587-97 11 p.

Research output: Contribution to journalReview article

Open Access
File
Life Style
Genes
Personal Narratives
Behavioral Genetics
Social Behavior
67 Citations (Scopus)

Obesity and cancer: mechanistic insights from transdisciplinary studies

Allott, E. H. & Hursting, S. D., 01 Dec 2015, In : Endocrine-Related Cancer. 22, 6, p. R365-R386

Research output: Contribution to journalReview article

Open Access
Obesity
Neoplasms
Prostatic Neoplasms
Breast Neoplasms
Weight Loss
3 Citations (Scopus)

Optimising the management of bronchiolitis in infants

McNaughten, B. & Bourke, T. W., 31 Oct 2015, In : The Practitioner. 259, 1784, p. 13-5, 2

Research output: Contribution to journalReview article

Bronchiolitis
Work of Breathing
Tachypnea
Auscultation
Secondary Care
7 Citations (Scopus)
341 Downloads (Pure)
Open Access
File
Metal Nanoparticles
Prostatic Neoplasms
Radiotherapy
Image-Guided Radiotherapy
Neoplasms
47 Citations (Scopus)
697 Downloads (Pure)

Research in Progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)

Heaney, L. G., Djukanovic, R., Woodcock, A., Walker, S., Matthews, J. G., Pavord, I. D., Bradding, P., Niven, R., Brightling, C. E., Chaudhuri, R., Arron, J. R., Choy, D. F., Cowan, D., Mansur, A., Menzies-Gow, A., Adcock, I., Chung, K. F., Corrigan, C., Coyle, P., Harrison, T. & 16 others, Johnston, S., Howarth, P., Lordan, J., Sabroe, I., Bigler, J., Smith, D., Catley, M., May, R., Pierre, L., Stevenson, C., Crater, G., Keane, F., Costello, R. W., Hudson, V., Supple, D. & Hardman, T., 23 Jul 2015, In : Thorax. 71, 2, p. 1587-189 3 p.

Research output: Contribution to journalReview article

Open Access
File
Biomedical Research
Asthma
Research
Drug Industry
Biomarkers

The human Nail apparatus - An update on anatomy, pathology and treatment

Loeser, C. R., Reid, L., Reeves, N., Sweeney, E. M. & Cotofana, S., 01 Jan 2015, In : Kosmetische Medizin. 36, 5, p. 184-191 8 p.

Research output: Contribution to journalReview article

Nails
Anatomy
Pathology
Therapeutics
Esthetics