School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Review article
2018
2 Citations (Scopus)

HER2 testing of gastro-oesophageal adenocarcinoma: a commentary and guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Committee

Wong, N. A. C. S., Amary, F., Butler, R., Byers, R., Gonzalez, D., Haynes, H. R., Ilyas, M., Salto-Tellez, M. & Taniere, P., 08 Feb 2018, In : Journal of Clinical Pathology.

Research output: Contribution to journalReview article

Molecular Pathology
Adenocarcinoma
Guidelines
National Health Programs
Biological Products
31 Citations (Scopus)

Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions

Sayed, S., Cherniak, W., Lawler, M., Tan, S. Y., El Sadr, W., Wolf, N., Silkensen, S., Brand, N., Looi, L. M., Pai, S. A., Wilson, M. L., Milner, D., Flanigan, J. & Fleming, K. A., 14 Mar 2018, In : Lancet. 391, 10133, p. 1939-1952

Research output: Contribution to journalReview article

Medicine
Pathology
Telepathology
Clinical Laboratory Information Systems
Public-Private Sector Partnerships
6 Citations (Scopus)
191 Downloads (Pure)

Interventions to increase attendance for diabetic retinopathy screening

Lawrenson, J. G., Graham-Rowe, E., Lorencatto, F., Burr, J., Bunce, C., Francis, J. J., Aluko, P., Rice, S., Vale, L., Peto, T., Presseau, J., Ivers, N. & Grimshaw, J. M., 15 Jan 2018, In : The Cochrane database of systematic reviews. 1, p. CD012054

Research output: Contribution to journalReview article

Open Access
File
Diabetic Retinopathy
Quality Improvement
Confidence Intervals
Delivery of Health Care
Cost-Benefit Analysis
2 Citations (Scopus)
156 Downloads (Pure)

Mechanistic Insights into Colorectal Cancer Phenomics from Fundamental and Organotypic Model Studies

Campbell, F. C., Loughrey, M. B., McClements, J., Deevi, R. K., Javadi, A. & Rainey, L., 01 Sep 2018, In : The American journal of pathology. 188, 9, p. 1936-1948

Research output: Contribution to journalReview article

Open Access
File
Colorectal Neoplasms
Neoplasms
Phenotype
Homeostasis
Genome
15 Downloads (Pure)

Meningococcal Disease in Northern Ireland - Past, Present & Future: MeningoNI Forum

Millar, B. C., Banks, L., Bourke, T. W., Cunningham, M., Dooley, J., Elshibly, S., Goldsmith, C. E., Fairley, D., Jackson, K., Lamont, S., Jessop, L., McCrudden, E., McConnell, D., McAuley, K., McKenna, J. P., Moore, P., Smithson, R., Stirling, J., Shields, M. & Moore, J. E., 01 May 2018, In : The Ulster Medical Journal. 87, 2, p. 83

Research output: Contribution to journalReview article

Open Access
File
Northern Ireland
Epidemiology
Charities
Disease Management
Meningitis
1 Citation (Scopus)
126 Downloads (Pure)

Metabolomics and Age-Related Macular Degeneration

EYE-RISK consortium, 27 Dec 2018, In : Metabolites. 9, 1

Research output: Contribution to journalReview article

Open Access
File
Metabolomics
Macular Degeneration
Biomarkers
Retina
Vitreous Body
7 Citations (Scopus)
65 Downloads (Pure)
Open Access
File
Nanoparticles
Vaccines
Developing Countries
Technology
Combined Vaccines
9 Citations (Scopus)
157 Downloads (Pure)

Modulation of three key innate immune pathways for the most common retinal degenerative diseases

Akhtar-Schäfer, I., Wang, L., Krohne, T. U., Xu, H. & Langmann, T., 17 Sep 2018, In : EMBO Molecular Medicine. 10, 9, p. 1-27 e8259.

Research output: Contribution to journalReview article

Open Access
File
Inflammasomes
Retinal Diseases
Retinal Dystrophies
Immunomodulation
Retinal Pigment Epithelium
10 Citations (Scopus)
98 Downloads (Pure)

Multidisciplinary European Low Dose Initiative (MELODI): strategic research agenda for low dose radiation risk research

Kreuzer, M., Auvinen, A., Cardis, E., Durante, M., Harms-Ringdahl, M., Jourdain, J. R., Madas, B. G., Ottolenghi, A., Pazzaglia, S., Prise, K. M., Quintens, R., Sabatier, L. & Bouffler, S., Mar 2018, In : Radiation and Environmental Biophysics. 57, 1, p. 5-15

Research output: Contribution to journalReview article

Open Access
File
Radiation
dosage
radiation
Research
radiation protection
29 Citations (Scopus)
230 Downloads (Pure)

Neurodegeneration in diabetic retinopathy: Does it really matter?

Simó, R., Stitt, A. W. & Gardner, T. W., 01 Sep 2018, In : Diabetologia. 61, 9, p. 1902-1912 11 p.

Research output: Contribution to journalReview article

Open Access
File
Diabetic Retinopathy
Diabetes Complications
Precision Medicine
Neuroprotective Agents
Neuroglia
6 Citations (Scopus)
153 Downloads (Pure)

On the origin of proteins in human drusen : The meet, greet and stick hypothesis

Bergen, A. A., Arya, S., Koster, C., Pilgrim, M. G., Wiatrek-Moumoulidis, D., van der Spek, P., Hauck, S. M., Boon, C. J. F., Emri, E., Stewart, A. J. & Lengyel, I., 17 Dec 2018, In : Progress in Retinal and Eye Research.

Research output: Contribution to journalReview article

Open Access
File
Proteins
Choroid
Macular Degeneration
Retinal Drusen
Retinal Pigment Epithelium
5 Citations (Scopus)
122 Downloads (Pure)

Opportunities and priorities for breast surgical research

Association of Breast Surgery Surgical Gap Analysis Working Group, 01 Oct 2018, In : Lancet Oncology. 19, 10, p. e521-e533 13 p.

Research output: Contribution to journalReview article

Open Access
File
Breast
Research
Neoadjuvant Therapy
Breast Neoplasms
Translational Medical Research
19 Citations (Scopus)

Patient and public involvement in the design of clinical trials: An overview of systematic reviews

Price, A., Albarqouni, L., Kirkpatrick, J., Clarke, M., Liew, S. M., Roberts, N. & Burls, A., Feb 2018, In : Journal of Evaluation in Clinical Practice. 24, 1, p. 240-253 14 p.

Research output: Contribution to journalReview article

Patient Participation
Meta-Analysis
Volunteers
Research
Language
21 Citations (Scopus)

Perioperative outcomes in the context of mode of anaesthesia for patients undergoing hip fracture surgery: systematic review and meta-analysis

O'Donnell, C. M., McLoughlin, L., Patterson, C. C., Clarke, M., McCourt, K. C., McBrien, M. E., McAuley, D. F. & Shields, M. O., Jan 2018, In : British Journal of Anaesthesia. 120, 1, p. 37-50 14 p.

Research output: Contribution to journalReview article

Hip Fractures
Meta-Analysis
Anesthesia
Confidence Intervals
Odds Ratio
15 Citations (Scopus)

Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer

Montroni, I., Ugolini, G., Saur, N. M., Spinelli, A., Rostoft, S., Millan, M., Wolthuis, A., Daniels, I. R., Hompes, R., Penna, M., Fürst, A., Papamichael, D., Desai, A. M., Cascinu, S., Gèrard, J. P., Myint, A. S., Lemmens, V. E. P. P., Berho, M., Lawler, M., De Liguori Carino, N. & 8 others, Potenti, F., Nanni, O., Altini, M., Beets, G., Rutten, H., Winchester, D., Wexner, S. D. & Audisio, R. A., 01 Nov 2018, In : European Journal of Surgical Oncology. 44, 11, p. 1685-1702 18 p.

Research output: Contribution to journalReview article

Rectal Neoplasms
Neoplasms
Advisory Committees
Life Expectancy
Practice Guidelines
61 Citations (Scopus)

Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet

Barbui, T., Tefferi, A., Vannucchi, A. M., Passamonti, F., Silver, R. T., Hoffman, R., Verstovsek, S., Mesa, R., Kiladjian, J-J., Hehlmann, R., Reiter, A., Cervantes, F., Harrison, C., Mc Mullin, M. F., Hasselbalch, H. C., Koschmieder, S., Marchetti, M., Bacigalupo, A., Finazzi, G., Kroeger, N. & 3 others, Griesshammer, M., Birgegard, G. & Barosi, G., May 2018, In : Leukemia. 32, 5, p. 1057-1069 13 p.

Research output: Contribution to journalReview article

Philadelphia Chromosome
Primary Myelofibrosis
Polycythemia Vera
Splenomegaly
Stem Cell Transplantation
1 Citation (Scopus)
62 Downloads (Pure)

Precision medicine for age-related macular degeneration: current developments and prospects

Biarnés, M., Vassiliev, V., Nogoceke, E., Emri, E., Rodríguez-Bocanegra, E., Ferraro, L., Garcia, M., Fauser, S., Monés, J., Lengyel, I. & Peto, T., 19 Jul 2018, In : Expert Review of Precision Medicine and Drug Development. 3, 4, p. 249-263 15 p.

Research output: Contribution to journalReview article

Open Access
File
Precision Medicine
Macular Degeneration
Risk Management
Atrophy
Life Style
87 Downloads (Pure)

Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease

Dey, T., Kalita, J., Weldon, S. & Taggart, C. C., 28 Aug 2018, In : Journal of Clinical Medicine. 7, 9, p. 1-20 244.

Research output: Contribution to journalReview article

Open Access
File
Protease Inhibitors
Chronic Obstructive Pulmonary Disease
Peptide Hydrolases
Therapeutics
Drug Delivery Systems
3 Citations (Scopus)
51 Downloads (Pure)
Open Access
File
Metabolomics
Biomarkers
Chronic Renal Insufficiency
Proteomics
Metabolites
3 Citations (Scopus)
17 Downloads (Pure)
Open Access
File
Oligodendroglia
Regulatory T-Lymphocytes
Myelin Sheath
Regeneration
Central Nervous System
2 Citations (Scopus)

Role of lens extraction and laser peripheral iridotomy in treatment of glaucoma

Pose-Bazarra, S. & Azuara-Blanco, A., Jan 2018, In : Current Opinion in Ophthalmology. 29, 1, p. 96-99 4 p.

Research output: Contribution to journalReview article

Intraocular Pressure
Glaucoma
Lenses
Lasers
Angle Closure Glaucoma
7 Citations (Scopus)

Teaching of anatomical sciences: A blended learning approach

Khalil, M. K., Abdel Meguid, E. M. & Elkhider, I. A., 01 Apr 2018, In : Clinical Anatomy. 31, 3, p. 323-329 7 p.

Research output: Contribution to journalReview article

Teaching
Learning
Educational Technology
Technology
Costs and Cost Analysis
3 Citations (Scopus)
115 Downloads (Pure)

The effect of community-based interventions for cardiovascular disease secondary prevention on behavioural risk factors

Lawlor, E. R., Bradley, D. T., Cupples, M. E. & Tully, M. A., Sep 2018, In : Preventive Medicine. 114, p. 24-38 15 p.

Research output: Contribution to journalReview article

Open Access
File
Secondary Prevention
Cardiovascular Diseases
Exercise
Meta-Analysis
Aptitude
14 Citations (Scopus)

The heterogeneity of chronic cough: a case for endotypes of cough hypersensitivity

Mazzone, S. B., Chung, K. F. & McGarvey, L., 01 Aug 2018, In : The Lancet Respiratory Medicine. 6, 8, p. 636-646 11 p.

Research output: Contribution to journalReview article

Cough
Hypersensitivity
Neural Pathways
Lung
2 Citations (Scopus)
55 Downloads (Pure)

The impact of transcription on metabolism in prostate and breast cancers

Poulose, N., Mills, I. G. & Steele, R. E., 01 Sep 2018, In : Endocrine-Related Cancer. 25, 9, p. R435-R452 8 p.

Research output: Contribution to journalReview article

Open Access
File
Prostatic Neoplasms
Breast Neoplasms
Lipid Metabolism
Neoplasms
Drug Repositioning
7 Citations (Scopus)
136 Downloads (Pure)
Open Access
File
Primary Myelofibrosis
Epigenomics
Polycythemia Vera
Essential Thrombocythemia
Neoplasms
9 Citations (Scopus)
126 Downloads (Pure)
Open Access
File
Legionella
Organelles
Weapons
Gene Deletion
Virulence Factors
2 Citations (Scopus)
375 Downloads (Pure)

The Untapped Potential of the Gaming Community: Narrative Review

Goodman, W., McFerran, E., Purves, R., Redpath, I. & Beeken, R. J., 25 Sep 2018, In : JMIR Serious Games. 6, 3, 10 p., e10161.

Research output: Contribution to journalReview article

Open Access
File
Health Behavior
Research
Video Games
Energy Intake
Sleep
3 Citations (Scopus)
222 Downloads (Pure)

Translating Mechanism-Based Strategies to Break the Obesity-Cancer Link: A Narrative Review

Smith, L. A., O'Flanagan, C. H., Bowers, L. W., Allott, E. H. & Hursting, S. D., Apr 2018, In : Journal of the Academy of Nutrition and Dietetics. 118, 4, p. 652-667 16 p.

Research output: Contribution to journalReview article

Open Access
File
obesity
Obesity
neoplasms
Neoplasms
Ketogenic Diet
1 Citation (Scopus)
77 Downloads (Pure)

UK & Ireland Prostate Brachytherapy Practice Survey 2014-2016

Corey, G., Mohamed Yoosuf, A. B., Workman, G., Byrne, M., Mitchell, D. M. & Jain, S., 30 Jun 2018, In : Journal of Contemporary Brachytherapy. 10, 3, p. 238-245 8 p.

Research output: Contribution to journalReview article

Open Access
File
Brachytherapy
Ireland
Prostate
Post and Core Technique
Cone-Beam Computed Tomography
24 Downloads (Pure)

Visual cycle modulators versus placebo or observation for the prevention and treatment of geographic atrophy due to age-related macular degeneration

Yeong, J. L., Loveman, E., Colquitt, J. L., Royle, P., Waugh, N. & Lois, N., 25 Oct 2018, In : Cochrane Database of Systematic Reviews. 10, 13 p., CD013154.

Research output: Contribution to journalReview article

Open Access
File
Geographic Atrophy
Macular Degeneration
Placebos
Observation
Safety
3 Citations (Scopus)

What are the origins and relevance of spontaneous bladder contractions? ICI-RS 2017

Drake, M. J., Fry, C. H., Hashitani, H., Kirschner-Hermanns, R., Rahnama'i, M. S., Speich, J. E., Tomoe, H., Kanai, A. J. & McCloskey, K. D., 23 Jan 2018, In : Neurourology and Urodynamics.

Research output: Contribution to journalReview article

Urinary Bladder
Research
Mucous Membrane
Urinary Tract
Smooth Muscle Myocytes
2017
3 Citations (Scopus)
164 Downloads (Pure)

Animal models of retinal vein occlusion

Khayat, M., Lois, N., Williams, M. & Stitt, A. W., 01 Dec 2017, In : Investigative Ophthalmology and Visual Science. 58, 14, p. 6175-6192 18 p.

Research output: Contribution to journalReview article

Open Access
File
Retinal Vein Occlusion
Animal Models
Primates
Rodentia
Lasers
3 Citations (Scopus)
201 Downloads (Pure)
Open Access
File
Radiation Oncology
Nanotechnology
Oncology
nanotechnology
Radiotherapy
329 Citations (Scopus)

A systematic review of outcomes following Stereotactic Ablative Radiotherapy in the treatment of early stage primary lung cancer. SABR for early stage NSCLC

Murray, P., Franks, K. & Hanna, G., 17 Feb 2017, In : British Journal of Radiology. 90, 1071, p. 1 45 p., 20160732.

Research output: Contribution to journalReview article

Radiosurgery
Lung Neoplasms
Radiotherapy
Therapeutics
Salvage Therapy
12 Citations (Scopus)

Can biomarkers help us hit targets in difficult-to-treat asthma?

Fricker, M., Heaney, L. G. & Upham, J. W., 13 Apr 2017, In : Respirology (Carlton, Vic.). 22, 3, p. 430-442

Research output: Contribution to journalReview article

Asthma
Biomarkers
Inflammation
Nitric Oxide
Precision Medicine
3 Citations (Scopus)
64 Downloads (Pure)

Cardiotoxicity Following Cancer Treatment.

Walls, G., Lyon, A. R., Harbinson, M. & Hanna, G., 01 Jan 2017, In : Ulster Medical Journal. 86, 1, p. 3-9

Research output: Contribution to journalReview article

Open Access
File
Neoplasms
Survival Rate
Therapeutic Uses
Therapeutics
Physicians
27 Citations (Scopus)

Circulating Levels of Interleukin 1-Receptor Antagonist and Risk of Cardiovascular Disease: Meta-Analysis of Six Population-Based Cohorts

Herder, C., de Las Heras Gala, T., Carstensen-Kirberg, M., Huth, C., Zierer, A., Wahl, S., Sudduth-Klinger, J., Kuulasmaa, K., Peretz, D., Ligthart, S., Bongaerts, B. W. C., Dehghan, A., Ikram, M. A., Jula, A., Kee, F., Pietilä, A., Saarela, O., Zeller, T., Blankenberg, S., Meisinger, C. & 5 others, Peters, A., Roden, M., Salomaa, V., Koenig, W. & Thorand, B., Jun 2017, In : Arteriosclerosis Thrombosis and Vascular Biology. 37, 6, p. 1222-1227 6 p.

Research output: Contribution to journalReview article

Interleukin-1 Receptors
Meta-Analysis
Cardiovascular Diseases
Interleukins
Population
13 Citations (Scopus)
186 Downloads (Pure)

Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer

Pérez-Ramírez, C., Cañadas-Garre, M., Molina, M. Á., Robles, A. I., Faus-Dáder, M. J. & Calleja-Hernández, M. Á., 28 Mar 2017, In : Mutation research/Reviews in Mutation Research. 771, p. 32-58 27 p.

Research output: Contribution to journalReview article

Open Access
File
Platinum
Non-Small Cell Lung Carcinoma
Drug Therapy
Meta-Analysis
Phosphatidylinositol 3-Kinases
2 Citations (Scopus)

Cough and severe asthma

Heaney, L. G., 01 Dec 2017, In : Pulmonary pharmacology & therapeutics. 47, p. 72-76 5 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Cough in the Athlete: CHEST Guideline and Expert Panel Report

Boulet, L-P., Turmel, J., Irwin, R. S., McGarvey, L. & CHEST Expert Cough Panel, Feb 2017, In : Chest. 151, 2, p. 441-454 14 p.

Research output: Contribution to journalReview article

Cough
Athletes
Guidelines
Exercise
Population
11 Citations (Scopus)
88 Downloads (Pure)

Development of core outcome sets for effectiveness trials of interventions to prevent and/or treat delirium (Del-COrS) : study protocol

Rose, L., Agar, M., Burry, L. D., Campbell, N., Clarke, M., Lee, J., Siddiqi, N., Page, V. J. & Del-COrS group, 18 Sep 2017, In : BMJ Open. 7, 9, p. e016371

Research output: Contribution to journalReview article

Open Access
File
Delirium
Consensus
Research Ethics
Palliative Care
Critical Illness
4 Citations (Scopus)

Diabetes-Related Neurological Implications and Pharmacogenomics

Rojas-Carranza, C. A., Bustos-Cruz, R. H., Pino-Pinzón, C. J., Ariza-Marquez, Y. V., Gómez-Bello, R. M. & Canadas Garre, M. L., 17 Mar 2017, In : Current Pharmaceutical Design. 23

Research output: Contribution to journalReview article

Pharmacogenetics
Neuroglia
Hyperglycemia
Cognition
Biochemical Phenomena
113 Citations (Scopus)

Diabetic retinopathy: current understanding, mechanisms, and treatment strategies

Duh, E. J., Sun, J. K. & Stitt, A. W., 20 Jul 2017, In : Insight. 2, 14

Research output: Contribution to journalReview article

Open Access
Pathology
Medical problems
Neuroglia
Regenerative Medicine
11 Citations (Scopus)
141 Downloads (Pure)

Elucidating the pathogenesis of pre-eclampsia using in vitro models of spiral uterine artery remodelling

McNally, R., Alqudah, A., Obradovic, D. & McClements, L., 01 Nov 2017, In : Current Hypertension Reports.

Research output: Contribution to journalReview article

Open Access
File
Uterine Artery
Pre-Eclampsia
Trophoblasts
Biomarkers
Placentation
5 Citations (Scopus)
185 Downloads (Pure)

Epigenetics in Myeloproliferative Neoplasms

McPherson, S., McMullin, M. F. & Mills, K., 25 Aug 2017, In : Journal of Cellular and Molecular Medicine. 8 p.

Research output: Contribution to journalReview article

Open Access
File
Epigenomics
Neoplasms
Mutation
DNA Methylation
Genes
24 Citations (Scopus)
250 Downloads (Pure)

Guidance Statement On BRCA1/2 Tumor Testing in Ovarian Cancer Patients

Capoluongo, E., Ellison, G., López-Guerrero, J. A., Penault-Llorca, F., Ligtenberg, M. J. L., Banerjee, S., Singer, C., Friedman, E., Markiefka, B., Schirmacher, P., Büttner, R., van Asperen, C. J., Ray-Coquard, I., Endris, V., Kamel-Reid, S., Percival, N., Bryce, J., Röthlisberger, B., Soong, R. & de Castro, D. G., 01 Jun 2017, In : Seminars in Oncology. 44, 3, p. 187-197 11 p.

Research output: Contribution to journalReview article

Open Access
File
Ovarian Neoplasms
Mutation
Neoplasms
Poly Adenosine Diphosphate Ribose
Manuscripts
45 Downloads (Pure)

Interventions to support female BRCA mutation carriers who have undergone risk reducing surgery - protocol

Jeffers, L., Reid, J., Fitzsimons, D., Morrison, P. J. & Dempster, M., 11 Dec 2017, In : Cochrane database of systematic reviews (Online). 2017, 12, 23 p., CD012894.

Research output: Contribution to journalReview article

Open Access
File
Mutation
3 Citations (Scopus)

Is electrolyte transfer across the urothelium important?: ICI-RS 2015

McCloskey, K. D., Vahabi, B. & Fry, C. H., Apr 2017, In : Neurourology and Urodynamics. 36, 4, p. 863-868 6 p.

Research output: Contribution to journalReview article

Urothelium
Electrolytes
Urine
Urinary Bladder
Research
5 Citations (Scopus)
138 Downloads (Pure)

Low-dose radiation-induced risk in spermatogenesis

Fukunaga, H., Butterworth, K. T., Yokoya, A., Ogawa, T. & Prise, K. M., 2017, In : International journal of radiation biology. 93, 12, p. 1291-1298 8 p.

Research output: Contribution to journalReview article

Open Access
File
Spermatogenesis
Radiation
Germ Cells
Fertility
Spermatozoa