School of Medicine, Dentistry and Biomedical Sciences

  • 97 Lisburn Road, Health Sciences Building

    BT9 7BL Belfast

    United Kingdom

Research Output 1973 2020

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Patent
2018

NOVEL COMPOUNDS AND USES

O'Neill, L. A. J., Coll, R., Cooper, M. A., Robertson, A. A. B., Schroder, K., Macleod, A. M. & Miller, D. J., 29 Nov 2018, Patent No. PCT/IB2017/053059, 24 May 2017

Research output: Patent

Patents and inventions
Prodrugs
Salts
Insulin
Chemical analysis
2017

Method and Kit for Detection of Bacterial Infection

Taggart, C., Weldon, S. & Scott, C., 2017, Patent No. 1509564.9, 06 Feb 2015

Research output: Patent

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

O'Neill, L. A. J., Coll, R., Cooper, M. A., Robertson, A. A. B., Schroder, K., Macleod, A. M. & Miller, D. J., 24 Aug 2017, Patent No. PCT/EP2017/053498, 16 Feb 2017, Priority date 16 Feb 2016, Priority No. 2016900535

Research output: Patent

Patents and inventions
Inflammasomes
Prodrugs
Hydrogen
Nitrogen
2016

MOLECULAR DIAGNOSTIC TEST FOR OESOPHAGEAL CANCER

Turkington, R., 09 Mar 2016, Patent No. 14/917,925, 09 Mar 2016

Research output: Patent

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

Coll, R., O'Neill, L. A. J., Cooper, M. A., Robertson, A. A. B. & Schroder, K., 25 Aug 2016, Patent No. PCT/AU2016/050103, 16 Feb 2016, Priority date 16 Feb 2015, Priority No. 2015900507

Research output: Patent

Inflammasomes
Patents and inventions
Urea
Chemical activation
2015

Methods for treating neurological disorders

Tolar, M., Hey, J., Kocis, P. & Yu, J., 2015, IPC No. WO2015143447, Patent No. PCT/US2015/022058

Research output: Patent

2014

Phosphorylated polyols, pyrophosphates, and derivatives thereof having biological activity

Lehn, J. M., Nicolau, Y. C., Pothukanuri, S., Brockman, A., Hey, J. & Yu, Y. J., May 2014, IPC No. A61K31/7028, C07F9/6564, A61K31/6615, A61K45/06, Patent No. US20140142052 A1

Research output: Patent

Diphosphates
Patents and inventions
Bioactivity
Derivatives
Chemical analysis
2013

Diagnosis and risk stratification of bladder cancer

Williamson, K., 2013, Patent No. PCT/GB2013/052705

Research output: Patent

2012

Compounds

Haigh, D., Johns, B. A. & Shotwell, J. B., May 2012, Patent No. WO2012/067663A1

Research output: Patent

Method for detection of, or risk of, bladder cancer

Williamson, K., 05 Mar 2012, Patent No. PCT/GB2010051255

Research output: Patent

2011

Polyphosphate and pyrophosphate derivative of saccharides

Lehn, J. M., Nicolau, Y. C., Jogireddy, R., Brockman, A. H., Hey, J. & Yu, Y. J., 2011, IPC No. A61K31/70, A01N43/04, Patent No. WO2012045009, US20140088036, US20140155334, EP2621273

Research output: Patent

Polyphosphates
Disaccharides
Oligosaccharides
Oxygen
Pharmaceutical Preparations

Therapeutic Compounds

Haigh, D., Johns, B. A. & Shotwell, J. B., Aug 2011, Patent No. WO2011/103063A1

Research output: Patent

2007

2-Heteroarylmethyl-4-(methoxymethyl)-N-acyl pyrrolidine compounds as antiviral agents, their preparation, pharmaceutical compositions, and use for treatment of hepatitis C.

Haigh, D., Hartley, C. D., Howes, P. D., Jarvest, R. L., Lazarides, L., Nerozzi, F. & Smith, S. A., Apr 2007, Patent No. WO 2007039142 A1

Research output: Patent

2-Heteroarylmethyl-4-(pyrazin-2-yl)-N-acyl pyrrolidine compounds as antiviral agents, their preparation, pharmaceutical compositions, and use for treatment of hepatitis C

Haigh, D., Hartley, C. D., Howes, P. D., Lazarides, L., Nerozzi, F. & Smith, S. A., Apr 2007, Patent No. WO 2007039145 A1

Research output: Patent

2-Heteroarylmethyl-4-pyrazin-2-yl-N-acyl pyrrolidine compounds as antiviral agents, their preparation, pharmaceutical compositions, and use for treatment of hepatitis C.

Haigh, D., Hartley, C. D., Howes, P. D., Lazarides, L., Nerozzi, F. & Smith, S. A., Apr 2007, Patent No. WO 2007039143 A1

Research output: Patent

Phosphitylation reactions in ionic liquids

Migaud, M., 2007, Patent No. GE EP 07 013 366.7

Research output: Patent

Preparation of azolylmethylpyrrolidinecarboxylates for treating viral infections

Haigh, D., Hartley, C. D., Howes, P. D., Jarvest, R. L., Lazarides, L., Nerozzi, F. & Smith, S. A., 2007, Patent No. WO 2007039144 A1

Research output: Patent

2006

Preparation of 4-(methoxycarbonyl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors.

Guidetti, R., Haigh, D., Hartley, C. D., Howes, P. D., Nerozzi, F. & Smith, S. A., May 2006, Patent No. WO 2006045613 A1

Research output: Patent

Preparation of 4-(pyrazin-2-yl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors.

Guidetti, R., Haigh, D., Hartley, C. D., Howes, P. D., Nerozzi, F. & Smith, S. A., May 2006, Patent No. WO 2006045615 A1

Research output: Patent

2005

Peptides Arenicins isolated from sea annelid worm Arenicola marina eliciting antibacterial effect.

Krasnodembskaya, A., Ovchinnikova, T., Aleshina, G., Balandin, S., Markelov, M. & Kokryakov, V., 25 Oct 2005

Research output: Patent

Preparation of N-acyldihydropyrroles as hepatitis C virus (HCV) inhibitors.

Haigh, D. & Slater, M. J., Nov 2005, Patent No. WO 2005103045 A1

Research output: Patent

2004

Inhibition of biofilm using LasB-directed inhibitors

Walker, B., JF, L., Martin, L. & McDowell, A., 2004, IPC No. British Patent Application 0310268.8, Patent No. 0310268.8

Research output: Patent

Preparation of 5-thiazole substituted 2-pyrrolidinecarboxylic acids as antiviral agents for hepatitis C virus

Haigh, D., Jackson, D. L., Shah, P. & Slater, M. J., Jul 2004, Patent No. WO 2004060889 A1

Research output: Patent

Preparation of acylated indoline and tetrahydroquinoline derivatives as hepatitis C virus (HCV) inhibitors.

Bravi, G., Grimes, R. M., Guidetti, R., Haigh, D., Hartley, C. D., Mordaunt, J. E., Shah, P. & Slater, M. J., Nov 2004, Patent No. WO 2004096210 A1

Research output: Patent

Preparation of acyl isoindoline derivatives and acyl isoquinoline derivatives as anti-viral agents.

Bravi, G., Corfield, J. A., Haigh, D., Lovegrove, V. L. H., Shah, P. & Slater, M. J., Nov 2004, Patent No. WO 2004096774 A1

Research output: Patent

Preparation of cyanothiazolylpyrrolidinecarboxylates and related compounds as antivirals

Burton, G., Goodland, H. S., Haigh, D., Kiesow, T. J., Ku, T. W. & Slater, M. J., Jan 2004, Patent No. WO 2004009543 A2

Research output: Patent

Synthesis of 1-acyl-pyrrolidine derivatives for the treatment of viral infections.

Haigh, D., Hartley, C. D., Howes, P. D., Jackson, D. L., Shah, P. & Slater, M. J., May 2004, Patent No. WO 2004037818 A1

Research output: Patent

2003

Preparation of azolylpyrrolidinecarboxylates as hepatitis C virus (HCV) inhibitors.

Bravi, G., Goodland, H. S., Haigh, D., Hartley, C. D., Lovegrove, V. L. H., Shah, P. & Slater, M. J., May 2003, Patent No. WO 2003037894 A1

Research output: Patent

Preparation of heteroaryl acyl pyrrolidine derivatives as antiviral agents.

Bravi, G., Guidetti, R., Haigh, D., Hartley, C. D., Howes, P. D., Jackson, D. L., Lovegrove, V. L. H., Shah, P., Slater, M. J. & Wareing, K. J., May 2003, Patent No. WO 2003037895 A1

Research output: Patent

Preparation of pyrazolopyridine derivatives as GSK-3 inhibitors.

Haigh, D., Hickey, D. M. B., Liddle, J., Slingsby, B. P., Ward, R. W. & Witherington, J., Jun 2003, Patent No. WO 2003045949 A1

Research output: Patent

2002

Preparation of pyrazolopyridines and pyrazolopyridazines as antidiabetics

Garland, S., Haigh, D., Hickey, D. M. B., Liddle, J., Smith, D. G., Witherington, J. & Ward, R. W., Mar 2002, Patent No. WO 2002024694 A1

Research output: Patent

2001

Pyrrole-2,5-dione derivatives for the treatment of diabetes.

Haigh, D., Slingsby, B. P., Smith, D. G. & Ward, R. W., Oct 2001, Patent No. WO 2001074771 A1

Research output: Patent

2000

Preparation of pyrroledione derivatives as inhibitors of glycogen synthase kinase-3.

Coghlan, M. P., Fenwick, A. E., Haigh, D., Holder, J. C., Ife, R. J., Reith, A. D., Smith, D. G. & Ward, R. W., Apr 2000, Patent No. WO 2000021927 A2

Research output: Patent

1998

Preparation of benzoxazinones and thienooxazinones as antiviral agents

Fenwick, A. E., Haigh, D., Gribble, A. D. & Slingsby, B. P., Oct 1998, Patent No. WO 9845298 A1

Research output: Patent

Thienoxazinone derivatives as antiviral agents.

Haigh, D., Smith, D. G. & Ward, R. W., Dec 1998, Patent No. WO 9854192 A1

Research output: Patent

1996

Preparation of benzoxazole and pyridine derivatives as antidiabetics.

Haigh, D. & Rami, H. K., Feb 1996, Patent No. WO 9604260 A1

Research output: Patent

Preparation of benzoxazole and pyridine derivatives as antidiabetics.

Haigh, D. & Rami, H. K., Feb 1996, Patent No. WO 9604261 A1

Research output: Patent

1995

Preparation of heterocyclylamino ether cardiovascular agents and antihyperglycemics

Haigh, D. & Cantello, B. C. C., Jun 1995, Patent No. WO 9517394 A1

Research output: Patent

1994

Heterocyclic compounds as pharmaceuticals

Haigh, D. & Sime, J. T., Jan 1994, Patent No. WO 9401420 A1

Research output: Patent

Heterocyclic derivatives and their use in pharmaceuticals.

Haigh, D. & Rami, H. K., Jun 1994, Patent No. WO 9413650 A1

Research output: Patent

1993

Heterocyclic compounds and their use in the treatment of type 2 diabetes

Haigh, D., Oct 1993, Patent No. WO 9321166 A1

Research output: Patent

1992

Preparation of [[(acylamino)alkoxy]benzyl]thiazolidinediones as hypoglycemics

Cantello, B. C. C., Haigh, D. & Hindley, R. M., May 1992, Patent No. WO 9207850 A1

Research output: Patent

Preparation of thiazolidinedione derivatives as cardiovascular agents

Bell, D. & Haigh, D., May 1992, Patent No. WO 9207838 A1

Research output: Patent

Preparation of thiazolidinediones as antihyperglycemic and antihyperlipemic agents

Cottam, G. P., Haigh, D. & Hindley, R. M., May 1992, Patent No. WO 9207839 A1

Research output: Patent

1990

(Heterocyclyloxyalkoxy)benzyl- and -benzylidenethiazolidinediones as hypoglycemics and hypolipidemics.

Duff, P., Haigh, D. & Hindley, R. M., Feb 1990, Patent No. EP 356214 A2

Research output: Patent

1989

Preparation of thiazolidinedione derivatives as antidiabetics and hypolipemics

Haigh, D. & Hindley, R. M., Jan 1989, Patent No. EP 299620 A1

Research output: Patent