School of Pharmacy

2025

3D-printed acyclovir nanocrystals: an advanced approach to herpes simplex treatment

Lopez-Vidal, L., Juskaite, K., Fandino, O., Fuster, M. G., Sangalli, M., Adhami, M., Wang, J., Palma, S. D., Volpe-Zanutto, F., Larrañeta, E. & Paredes, A. J., Jun 2025, In: Applied Materials Today. 44, 14 p., 102695.

Research output: Contribution to journal › Article › peer-review

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3D printed cacao-based formulations as nutrient carriers for immune system enhancement

Milliken, R. L., Dedeloudi, A., Vong, E., Irwin, R., Andersen, S. K., Wylie, M. P. & Lamprou, D. A., 2025, In: Current Research in Food Science. 10, 10 p., 100949.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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3D printed hydrogels: a promising material for biomedical applications

Bickerstaff, E., Mehdi-Sefiani, H., Chicardi, E., Sepúlveda, R., Pérez-Puyana, V. M., Adhami, M., Larrañeta, E. & Domínguez-Robles, J., 28 Feb 2025, Hydrogels in drug delivery. Paredes, A. J., Larrañeta, E., Laverty, G. & Donnelly, R. F. (eds.). Elsevier Inc., p. 379-412 34 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Advanced therapeutic technologies for malaria, tuberculosis, HIV infection and neglected tropical diseases

Dube , A., Laverty, G. & Balogun, M., 23 Mar 2025, (Early online date) In: Advanced Therapeutics.

Research output: Contribution to journal › Article › peer-review

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Airway total bacterial density, microbiota community composition and relationship with clinical parameters in bronchiectasis

Alfahl, Z., Einarsson, G. G., Elborn, J. S., Gilpin, D. F., O'Neill, K., Ferguson, K., Hill, A. T., Loebinger, M. R., Carroll, M., Gatheral, T., De Soyza, A., Chalmers, J. D., Johnson, C., Hurst, J. R., Brown, J. S., Bradley, J. M. & Tunney, M. M., Jan 2025, In: Respiratory Medicine. 236, 8 p., 107906.

Research output: Contribution to journal › Article › peer-review

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Allosteric modulation and biased signalling at free fatty acid receptor 2

Zhang, X., Guseinov, A.-A., Jenkins, L., Valentini, A., Marsango, S., Schultz-Knudsen, K., Ulven, T., Rexen Ulven, E., Tikhonova, I. G., Milligan, G. & Zhang, C., 18 Jun 2025, (Early online date) In: Nature.

Research output: Contribution to journal › Article › peer-review

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A low-dimensional cross-attention model for link prediction with applications to drug repurposing

Chen, G.-J., Guo, G.-D., Martin, S. L. & Wang, H., 15 Jun 2025, In: Knowledge-Based Systems. 319, 11 p., 113562.

Research output: Contribution to journal › Article › peer-review

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Amphotericin B PLGA nanoparticles loaded dissolving microneedle patches in treating cutaneous fungal infections

Peng, K., Ammar, A. A., Himawan, A., Dai, X., Duncan, R., Gilmore, B. F., Donnelly, R. F. & Vora, L. K., Apr 2025, In: Journal of Drug Delivery Science and Technology. 106, 10 p., 106697.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

23 Downloads (Pure)

A multifunctional long-acting antimicrobial hydrogel for treating wound

Xu, K. & Zhang, S., May 2025.

Research output: Contribution to conference › Abstract

Open Access

A multipurpose silicone elastomer vaginal ring releasing dapivirine and Cu²⁺/Zn²⁺ ions for HIV prevention and non-hormonal contraception

Shen, X., Boyd, P., Dallal Bashi, Y. H., McCoy, C. F., Zhao, X. & Malcolm, R. K., 15 Apr 2025, In: International Journal of Pharmaceutics. 674, 17 p., 125442.

Research output: Contribution to journal › Article › peer-review

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Antibiotic prescribing for care-home residents: a population-based, cross-classified multilevel analysis in Scotland, UK

De Souza, N., Guthrie, B., Grant, S., Lorencatto, F., Dickson, J., Herbec, A., Hughes, C., Sneddon, J., Donnan, P. T. & Marwick, C. A., 09 Jan 2025, In: Age and Ageing. 54, 1, 10 p., afae288.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

2 Downloads (Pure)

Antifungal stewardship in the UK: where are we now?

Schelenz, S., Agrawal, S., Brady, A., Kiely, G., Riaz, Z., Howes, E., Felton, T., Micallef, C., Tyler, N., Bicanic, T. & White, P. L., Feb 2025, In: JAC-Antimicrobial Resistance. 7, 1, 8 p., dlae209.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Application of microarray patches for the transdermal administration of psychedelic drugs in micro-doses

Fandiño, O. E., Hutton, A. R. J., Zhang, C., Abbate, M. T. A., Naser, Y. A., Li, Y., Paredes, A. J. & Donnelly, R. F., Feb 2025, In: European Journal of Pharmaceutics and Biopharmaceutics. 207, 13 p., 114603.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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A qualitative interview study of care home managers’ experiences of medicines optimisation for residents with dementia during the COVID-19 pandemic

Alsulami, N., Hughes, C. M. & Barry, H. E., 20 Jan 2025, In: BMJ Open. 15, 9 p., e091645.

Research output: Contribution to journal › Article › peer-review

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Archaea: taking biocatalysis to the extreme

Kelly, S., 10 Feb 2025, The Microbiologist.

Research output: Contribution to specialist publication › Featured article

Assessment of leachables and extractables in “super-swelling” hydrogel-forming microarray patches

Anjani, Q. K., McKenna, P. E., Larrañeta, E., Manesiotis, P., Luo, Y., Adhami, M., Volpe-Zanutto, F., Orr, G., Roussel, S. & Donnelly, R. F., 31 May 2025, (Early online date) In: Drug Delivery and Translational Research. 13 p.

Research output: Contribution to journal › Article › peer-review

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A state-of-the-art appraisal of nanomaterials in microneedles in the delivery of therapeutics and vaccines

Witika, B. A., Hutton, A., Makoni, P. A. & Donnelly, R. F., 01 Mar 2025, In: Advanced NanoBiomed Research. 5, 3, 23 p., 2400162.

Research output: Contribution to journal › Article › peer-review

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Atovaquone-induced activation of the PERK/eIF2α signaling axis mitigates metabolic radiosensitisation

Feng, J., Pathak, V., Byrne, N. M., Chambers, S., Wang, T., Islam, R., Medina, R. J. & Coulter, J. A., 02 Apr 2025, In: Cell communication and signaling : CCS. 23, 1, 17 p., 164.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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B307: A multifunctional polymer coating for eradication of catheter-associated urinary tract infections

Zhang, S. & Xu, K., 31 Mar 2025, p. 527. 1 p.

Research output: Contribution to conference › Poster › peer-review

Barriers and facilitators to medicines use in patients with vision impairment: a theory-informed qualitative study of patients and caregivers

Kentab, B. Y., Barry, H. E., Al-Aqeel, S. A. & Hughes, C. M., Apr 2025, In: Health Expectations. 28, 2, 13 p., e70234.

Research output: Contribution to journal › Article › peer-review

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Bimodal dissolving microneedles with nanoparticle coating and encapsulation for extended dual-drug delivery

Li, M., Sabri, A. H. B., Qin, N., Peng, K., Abbate, M., Paredes, A. J., McCarthy, H. O., Vora, L. K. & Donnelly, R. F., 26 May 2025, (Early online date) In: Small. 14 p., 2502904.

Research output: Contribution to journal › Article › peer-review

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Biodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: formulation, in vitro toxicity and in vivo clearance

Al-Jamal, W. T., Reboredo, C., Abdi, U., Curci, P., Qadadeh, R., Alotaibi, H., Casettari, L. & Hatahet, T., 05 Jan 2025, In: International Journal of Pharmaceutics. 668, 13 p., 124963.

Research output: Contribution to journal › Article › peer-review

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6 Citations (Scopus)

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Biofunctionalisation of porous additively manufactured magnesium-based alloys for Orthopaedic applications: A review

Sadat Hashemi, T., Jaiswal, S., McCarthy, H. O., Levingstone, T. J. & Dunne, N. J., Apr 2025, In: Biomaterials Advances. 169, 214170.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Biomedical application of cold plasma: navigating through plasma types and devices by antimicrobial effectiveness and tissue tolerance

Thompson, T. P., Connelly, A., Kelly, S., Duncan, R. M., Maybin, J.-A., McDonnell, C., Melvage, A., McClenaghan, L. A., Dedeloudi, A., Lamprou, D. A., Schaer, T. P., Bourke, P., Hickok, N. J., Gilmore, B. F. & Freeman, T. A., 26 Mar 2025, (Early online date) In: Advanced Therapeutics. 14 p., 2400339.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Biopolymeric 3D printed scaffolds as a versatile tissue engineering treatment for congenital diaphragmatic hernia

Dedeloudi, A., Farzeen, F., Lesutan, V.-N., Irwin, R., Wylie, M. P., Andersen, S., Eastwood, M. P. & Lamprou, D. A., 15 Mar 2025, In: International Journal of Pharmaceutics. 672, 10 p., 125313.

Research output: Contribution to journal › Article › peer-review

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2 Citations (Scopus)

6 Downloads (Pure)

BOS-318 treatment enhances elexacaftor–tezacaftor–ivacaftor-mediated improvements in airway hydration and mucociliary transport

Douglas, L. E. J., Reihill, J. A. & Martin, S. L., Jan 2025, In: ERJ Open Research. 11, 1, 8 p., 00445-2024.

Research output: Contribution to journal › Article › peer-review

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Cell-penetrating proteins and peptides as a promising theragnostic agent for neurodegenerative disorder

Pancholi, B., Choudhary, M. K., Kumar, M., Babu, R., Vora, L. K., Khatri, D. K. & Garabadu, D., May 2025, In: Journal of Drug Delivery Science and Technology. 107, 19 p., 106816.

Research output: Contribution to journal › Review article › peer-review

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Chapter 6 - Hydrogel-forming microarray patches for drug delivery and diagnostic applications

Hutton, A. R. J., Anjani, Q. K., Naser, Y. A. & Donnelly, R. F., 2025, Hydrogels in Drug Delivery. Paredes, A. J., Larrañeta, E., Laverty, G. & Donnelly, R. F. (eds.). Elsevier Inc., p. 221-239 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Characteristics of hydrogels as a coating for microneedle transdermal delivery systems with agomelatine

Wojtyłko, M., Nowicka, A. B., Froelich, A., Szybowicz, M., Banaszek, T., Tomczak, D., Kuczko, W., Wichniarek, R., Budnik, I., Jadach, B., Kordyl, O., Białek, A., Krysztofiak, J., Osmałek, T. & Lamprou, D. A., 15 Jan 2025, In: Molecules (Basel, Switzerland). 30, 2, 31 p., 322.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Combining analysis of individual and wastewater whole genome sequencing improves SARS-CoV-2 surveillance

Troendle, E. P., Lee, A. J., Reyne, M. I., Allen, D. M., Bridgett, S. J., Radulescu, C. H., Glenn, M., Wilkins, J.-P., Rubino, F., Firoozi Nejad, B., McSparron, C., Niebel, M., Fairley, D. J., Binley, K. E., Creevey, C. J., McKinley, J. M., Skvortsov, T., Gilpin, D. F., McGrath, J. W. & Bamford, C. G. G. & 1 others, Simpson, D. A., 15 Sept 2025, In: Water Research. 284, 14 p., 123953.

Research output: Contribution to journal › Article › peer-review

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Controlled release of amitriptyline via the transdermal route using SmartReservoirs and hydrogel-forming microneedles

Abraham, A. M., Simon, A., Anjani, Q. K., Jiang, Y., Adhami, M., Domínguez-Robles, J., Larrañeta, E. & Donnelly, R. F., Nov 2025, In: Biomaterials Advances. 176, 16 p., 214361.

Research output: Contribution to journal › Article › peer-review

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Decoding oncogenic secrets of regulator of chromosome condensation 1: A breakthrough mechanistic evidence from breast and lung cancer models

El-Tanani, M., Satyam, S. M., Rabbani, S. A., Obeidat, R. M., El-Tanani, Y., Aljabali, A. A. A. & Hatahet, T., 31 Mar 2025, In: PLOS ONE. 20, 3, 18 p., e0319748.

Research output: Contribution to journal › Article › peer-review

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Delivery of islatravir via high drug‐load, long‐acting microarray patches for the prevention or treatment of human immunodeficiency virus

Anjani, Q. K., Johnson, A. R., Sabri, A. H., Lutz, R., Tignor, S., Ballard, J., Rudd, N., Zhao, L., Vora, L. K., Barrett, S. E., Wagner, A. & Donnelly, R. F., 14 Mar 2025, In: Advanced Healthcare Materials. 14, 7, 14 p., 2403615.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Design and characterization of hollow microneedles for localized intrascleral drug delivery of ocular formulations

Gade, S., Vora, L. K. & Singh Thakur, R. R., Feb 2025, In: Methods. 234, p. 196-210 15 p.

Research output: Contribution to journal › Article › peer-review

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2 Citations (Scopus)

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Development of a core outcome set for clinical trials targeting interventions aiming to improve adherence to appropriate polypharmacy in older people - an international consensus study

Al Shaker, H., Barry, H. & Hughes, C., Apr 2025, In: Age and Ageing. 54, 4, 10 p., afaf102.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Development of a nano-vaccine for high-grade serous ovarian cancer

Saha, C., Elkashif, A., Gilmore, E. J., Jiang, B., Sun, Y., Duary, R. K., Buckley, N., Dunne, N. J. & McCarthy, H. O., 07 Jun 2025, In: Biomaterials Science. 13, 11, p. 2908-2924 17 p.

Research output: Contribution to journal › Article › peer-review

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Development of axitinib-loaded polymeric ocular implants for the treatment of posterior ocular diseases

Annuryanti, F., Adhami, M., Abdi, U., Robles, J.-D., Larrañeta, E., Vora, L. K. & Raghu Raj Singh, T., 25 Jan 2025, In: International Journal of Pharmaceutics. 669, 13 p., 125099.

Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Development of rapidly dissolving microneedles integrated with Valsartan-loaded nanoliposomes for transdermal drug delivery: in vitro and ex vivo evaluation

Khalid, R., Mahmood, S., Sofian, Z. M., Chik, Z. & Ge, Y., 07 Apr 2025, In: Pharmaceutics. 17, 4, 27 p., 483.

Research output: Contribution to journal › Article › peer-review

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Development of superhydrophobic poly(vinyl chloride) materials with enhanced antibacterial properties for the prevention of ventilator-associated pneumonia

Li, J., Ross, J., Irwin, N. J., Carson, L., Jones, D. S., McCoy, C. P. & Wylie, M. P., 30 Jun 2025, In: Applied Surface Science. 695, 9 p., 162904.

Research output: Contribution to journal › Article › peer-review

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Discovery and characterisation of novel poly-histidine-poly-glycine peptides as matrix metalloproteinase inhibitors

Wang, H., Cai, W., Tang, Z., Fu, J., Konig, E., Zhang, N., Chen, X., Chen, T. & Shaw, C., 12 May 2025, In: Biomolecules. 15, 5, 706.

Research output: Contribution to journal › Article › peer-review

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Discovery and optimisation of novel Bombinin-derived peptides from Bombina variegata against Staphylococcus aureus

Liu, J., Yao, K., Sun, R., Ma, X., Ma, C., Chen, X., Jiang, Y., Wang, T., Chen, T., Shaw, C., Zhou, M. & Wang, L., 29 Apr 2025, (Early online date) In: Probiotics and Antimicrobial Proteins. 22 p.

Research output: Contribution to journal › Article › peer-review

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Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform

Paris, J. L., Vora, L. K., Pérez-Moreno, A. M., Martín-Astorga, M. D. C., Naser, Y. A., Anjani, Q. K., Cañas, J. A., Torres, M. J., Mayorga, C. & Donnelly, R. F., 25 Jan 2025, In: International Journal of Pharmaceutics. 669, 125064.

Research output: Contribution to journal › Article › peer-review

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2 Citations (Scopus)

6 Downloads (Pure)

D-peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention

Pentlavalli, S., Coulter, S. M., An, Y., Cross, E. R., Sun, H., Moore, J. V., Bin Sabri, A., Greer, B., Vora, L., McCarthy, H. O. & Laverty, G., 10 Mar 2025, In: Journal of Controlled Release. 379, p. 30-44 15 p.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

8 Downloads (Pure)

Effects of hyperoxia on pulmonary inflammation and organ injury in a human in vivo model (HIPI): study protocol of a randomised, double-blind, placebo-controlled trial

Linden, D., Dorrian, D., Tandel, S., McKelvey, M., Bailey, M., Conlon, J., Moore, D., Carr, S., Taggart, C. C., Bradley, J. M., Kidney, J., OKane, C. M. & McAuley, D. F., Feb 2025, In: BMJ Open Respiratory Research. 12, 1, e002393.

Research output: Contribution to journal › Article › peer-review

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Emerging technologies for ocular drug delivery

Vora, L. K. & Singh Thakur , R. R., 27 Feb 2025, Controlled Release Society Indian Chapter News Letter, 16, p. 35-43 10 p.

Research output: Contribution to specialist publication › Article

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Emerging trends in long-acting sustained drug delivery for glaucoma management

So, Y. H., Mishra, D., Gite, S., Sonawane, R., Waite, D., Shaikh, R., Vora, L. K. & Thakur, R. R. S., Jun 2025, In: Drug Delivery and Translational Research. 15, 6, p. 1907-1934 28 p.

Research output: Contribution to journal › Review article › peer-review

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3 Citations (Scopus)

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Engineering of antimicrobial peptide Brevinin-1pl: arginine, lysine, and histidine substitutions enhance antimicrobial-anticancer efficacy with reduced cytotoxicity

Wang, J., Zeng, F., Chen, X., Wang, T., Wang, L., Zhou, M., Jiang, Y., Chen, T., Fang, Y. & Zhang, J., 19 May 2025, In: Frontiers in Chemistry. 13, 1579097.

Research output: Contribution to journal › Article › peer-review

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Enhanced antibacterial and corrosion resistance performance of fluorine-doped diamond-like carbon coatings on 316 L stainless steel

Wang, Y., Olugbade , T. O., Wackerow, S., Cai, Y., Zhang, S., Abdolvand, A., Zolotovskaya, S. A. & Zhao, Q., 01 Apr 2025, (Early online date) In: Colloids and Surfaces B: Biointerfaces. 114666.

Research output: Contribution to journal › Article › peer-review

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