• 97 Lisburn Road, Medical Biology Centre

    BT9 7BL Belfast

    United Kingdom

Research Output

Filter
Review article
2020

Peptide nanomaterials for drug delivery applications

Pentlavalli, S., Coulter, S. & Laverty, G., 23 Mar 2020, In : Current Protein and Peptide Science. 21, 4, p. 401 - 412 12 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Transaminases for industrial biocatalysis: novel enzyme discovery

Kelly, S. A., Mix, S., Moody, T. S. & Gilmore, B. F., 16 Apr 2020, In : Applied Microbiology and Biotechnology.

Research output: Contribution to journalReview article

Open Access
File
6 Downloads (Pure)
2019

An update on Exosomes as Drug Delivery Vehicles: Obstacles to its Clinical Translation

Ali, A., Maguire, A. & Furlong, F., 02 Apr 2019, In : Novel Approaches in Drug Designing and Development. 5, 1, p. 0019

Research output: Contribution to journalReview article

Application of nanotechnology to target and exploit tumour associated proteases

Cogo, F., Williams, R., Burden, R. E. & Scott, C. J., 01 Nov 2019, In : Biochimie. 166, p. 112-131

Research output: Contribution to journalReview article

1 Citation (Scopus)

A systematic review of pharmacist-led medicines review services in New Zealand – is there equity for Māori older adults?

Hikaka, J., Hughes, C., Jones, R., Connolly, M. J. & Martini, N., 14 Jan 2019, In : Research in Social and Administrative Pharmacy. 12 p.

Research output: Contribution to journalReview article

British thoracic society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Stuart Elborn, J., Andres Floto, R., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Peter Kelleher, W., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 01 Jan 2019, In : Thorax. 74, 74.

Research output: Contribution to journalReview article

Open Access
38 Citations (Scopus)
Open Access
File
2 Citations (Scopus)
85 Downloads (Pure)

Exploiting Current Understanding of Hypoxia Mediated Tumour Progression for Nanotherapeutic Development

Feng, J., Byrne, N. M., Al Jamal, W. & Coulter, J. A., 11 Dec 2019, In : Cancers. 11, 12, 25 p., 1989.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
33 Downloads (Pure)

Exploring the Potential of MicroRNA Let-7c as a Therapeutic for Prostate Cancer

Mulholland, E. J., Green, W. P., Buckley, N. E. & McCarthy, H. O., 22 Oct 2019, In : Molecular Therapy: Nucleic Acids. 18, p. 927-937 11 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
40 Downloads (Pure)

GIP receptor: Expression in neuroendocrine tumours, internalization, signalling from endosomes and structure-function relationship studies

Reubi, J. C., Fourmy, D., Cordomi, A., Tikhonova, I. G. & Gigoux, V., 16 Dec 2019, In : Peptides. p. 170229

Research output: Contribution to journalReview article

Gut Check Time: Antibiotic Delivery Strategies to Reduce Antimicrobial Resistance

Kelly, S. A., Rodgers, A. M., O'Brien, S. C., Donnelly, R. F. & Gilmore, B. F., 19 Nov 2019, In : Trends in Biotechnology.

Research output: Contribution to journalReview article

1 Citation (Scopus)

MicroRNAs in Pancreatic Cancer biomarkers, prognostic, and therapeutic modulators

Daoud, A. Z., Mulholland, E. J., Cole, G. & McCarthy, H. O., 21 Nov 2019, In : BMC Cancer. 19, 1, p. 1130

Research output: Contribution to journalReview article

Open Access
File
44 Downloads (Pure)

The lung and gut microbiome: what has to be taken into consideration for cystic fibrosis?

Héry-Arnaud, G., Boutin, S., Cuthbertson, L., Elborn, S. J. & Tunney, M. M., Jan 2019, In : Journal of Cystic Fibrosis. 18, 1, p. 13-21 9 p.

Research output: Contribution to journalReview article

Open Access
6 Citations (Scopus)

Tumor Cell Dormancy and Reactivation in Bone: Skeletal Biology and Therapeutic Opportunities

Byrne, N. M., Summers, M. A. & McDonald, M. M., Mar 2019, In : JBMR plus. 3, 3, 8 p., e10125.

Research output: Contribution to journalReview article

Open Access
File
51 Downloads (Pure)
2018

Application of ω-Transaminases in the Pharmaceutical Industry

Kelly, S. A., Pohle, S., Wharry, S., Mix, S., Allen, C. C. R., Moody, T. S. & Gilmore, B. F., 10 Jan 2018, In : Chemical Reviews. 118, 1, p. 349-367 19 p.

Research output: Contribution to journalReview article

81 Citations (Scopus)

Characterisation of drug delivery vehicles using atomic force microscopy: current status

Smith, J. R., Olajumoke Bolanle Olusanya, T. & Lamprou, D., 07 Nov 2018, (Accepted) In : Expert Opinion on Drug Delivery.

Research output: Contribution to journalReview article

Open Access
File
30 Downloads (Pure)

Cold atmospheric plasma is a viable solution for treating orthopedic infection: A review

Nguyen, L., Lu, P., Boehm, D., Bourke, P., Gilmore, B. F., Hickok, N. J. & Freeman, T. A., 19 Dec 2018, In : Biological Chemistry. 400, 1, p. 77-86

Research output: Contribution to journalReview article

6 Citations (Scopus)

Cold Plasmas for Biofilm Control: Opportunities and Challenges

Gilmore, B. F., Flynn, P. B., O'Brien, S., Hickok, N., Freeman, T. & Bourke, P., 01 Jun 2018, In : Trends in Biotechnology. 36, 6, p. 627-638

Research output: Contribution to journalReview article

30 Citations (Scopus)

Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review

Yu, D-G., Li, J-J., Williams, G. R. & Zhao, M., 14 Aug 2018, In : Journal of controlled release : official journal of the Controlled Release Society. p. 1-68

Research output: Contribution to journalReview article

Open Access
File
83 Citations (Scopus)
205 Downloads (Pure)

Enhanced nanoparticle delivery exploiting tumour responsive formulations.

Bennie, L. A., McCarthy, H. & Coulter, J., 21 Nov 2018, In : Cancer Nanotechnology. 9, 10

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
209 Downloads (Pure)

Hydrogels for Hydrophobic Drug Delivery. Classification, Synthesis and Applications

Larrañeta, E., Stewart, S., Ervine, M., Al-Kasasbeh, R. & Donnelly, R. F., 24 Jan 2018, In : Journal of Functional Biomaterials. 9, 1, p. 1-20 13.

Research output: Contribution to journalReview article

Open Access
File
34 Citations (Scopus)
566 Downloads (Pure)

Impact of medication reconciliation for improving transitions of care

Redmond, P., Grimes, T. C., Mcdonnell, R., Boland, F., Hughes, C. & Fahey, T., 23 Aug 2018, In : Cochrane Database of Systematic Reviews. 2018, 8, CD010791.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
46 Downloads (Pure)

Interventions to improve the appropriate use of polypharmacy for older people

Rankin, A., Cadogan, C. A., Patterson, S. M., Kerse, N., Cardwell, C. R., Bradley, M. C., Ryan, C. & Hughes, C., 03 Sep 2018, In : The Cochrane database of systematic reviews. 9, p. CD008165

Research output: Contribution to journalReview article

Open Access
File
28 Citations (Scopus)
263 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
130 Downloads (Pure)
Open Access
File
3624 Downloads (Pure)

Stimuli responsive polymeric systems for cancer therapy

Alsuraifi, A., Curtis, A., Lamprou, D. A. & Hoskins, C., 22 Aug 2018, In : Pharmaceutics. 10, 3, 17 p., 136.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
171 Downloads (Pure)

Understanding plasma biofilm interactions for controlling infection and virulence

Flynn, P. B. & Gilmore, B. F., 07 Jun 2018, In : Journal of Physics D: Applied Physics. 51, 26, 263001.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Understanding the basis of transcutaneous vaccine delivery

Gamazo, C., Pastor, Y., Larrañeta, E., Berzosa, M., Irache, J. M. & Donnelly, R. F., 07 Dec 2018, In : Therapeutic Delivery. 10, 1, p. 63-80 18 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2017

Critical Review: Injectability of Calcium Phosphate Pastes and Cements

O'Neill, R., McCarthy, HO., Montufar, E., Ginebra, M-P., Wilson, DI., Lennon, A. & Dunne, N., 01 Mar 2017, In : Acta Biomaterialia. 50, p. 1 19 p.

Research output: Contribution to journalReview article

Open Access
File
61 Citations (Scopus)
429 Downloads (Pure)
Open Access
File
18 Citations (Scopus)
209 Downloads (Pure)

Microneedles for enhanced transdermal and intraocular drug delivery

Moffatt, K., Wang, Y., Raj Singh, T. R. & Donnelly, R. F., Oct 2017, In : Current Opinion in Pharmacology. 36, p. 14-21 8 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

MicroRNA as Therapeutic Targets for Chronic Wound Healing

Mulholland, E., Dunne, N. & McCarthy, H., 15 Sep 2017, In : Molecular Therapy: Nucleic Acids. 8, p. 46-55

Research output: Contribution to journalReview article

Open Access
File
29 Citations (Scopus)
147 Downloads (Pure)
2016

Delivery of nucleic acids for cancer gene therapy: overcoming extra- and intra-cellular barriers

McErlean, E. M., McCrudden, C. M. & McCarthy, H. O., 01 Sep 2016, In : Therapeutic Delivery. 7, 9, p. 619-37 19 p.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
244 Downloads (Pure)
Open Access
File
170 Citations (Scopus)
1174 Downloads (Pure)

Microneedles: A New Frontier in Nanomedicine Delivery

Larrañeta, E., McCrudden, M. T. C., Courtenay, A. & Donnelly, R. F., May 2016, In : Pharmaceutical Research. 33, 5, p. 1055-1073 19 p.

Research output: Contribution to journalReview article

Open Access
File
108 Citations (Scopus)
418 Downloads (Pure)

MiRNA 34a: a therapeutic target for castration-resistant prostate cancer

Chalanqui, M. J., O'Doherty, M., Dunne, N. J. & McCarthy, H. O., 28 Mar 2016, In : Expert Opinion on Therapeutic Targets. 20, 9, p. 1075-1085 11 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)
2015

Designer peptide delivery systems for gene therapy

Loughran, S. P., McCrudden, C. M. & McCarthy, H. O., Apr 2015, In : European Journal of Nanomedicine. 7, 2, p. 85-96 12 p.

Research output: Contribution to journalReview article

Open Access
File
10 Citations (Scopus)
322 Downloads (Pure)

DNA vaccination for prostate cancer: key concepts and considerations

Cole, G., McCaffrey, J., Ali, A. A. & McCarthy, H. O., 02 Jul 2015, In : Cancer Nanotechnology. 6, 2.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
230 Downloads (Pure)

Microneedle characterisation: the need for universal acceptance criteria and GMP specifications when moving towards commercialisation

Lutton, R. E. M., Moore, J., Larrañeta, E., Ligett, S., Woolfson, A. D. & Donnelly, R. F., Aug 2015, In : Drug Delivery and Translational Research. 5, 4, p. 313-331 19 p.

Research output: Contribution to journalReview article

Open Access
File
30 Citations (Scopus)
1630 Downloads (Pure)

Microneedles: an innovative platform for gene delivery

McCaffrey, J., Donnelly, R. F. & McCarthy, H. O., Aug 2015, In : Drug Delivery and Translational Research. 5, 4, p. 424-437

Research output: Contribution to journalReview article

24 Citations (Scopus)
Open Access
File
7 Citations (Scopus)
400 Downloads (Pure)

The utility of animal models in developing immunosuppressive agents

McDaid, J., Scott, C. J., Kissenpfennig, A., Chen, H. & Martins, P. N., 15 Jul 2015, In : European Journal of Pharmacology. 759, p. 295-302 8 p.

Research output: Contribution to journalReview article

File
6 Citations (Scopus)
741 Downloads (Pure)

Transdermal drug delivery: Innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum

Alkilani, A. Z., McCrudden, M. T. C. & Donnelly, R. F., 22 Oct 2015, In : Pharmaceutics. 7, 4, p. 438-470 33 p.

Research output: Contribution to journalReview article

Open Access
File
149 Citations (Scopus)
6 Downloads (Pure)
2014

Current status of gene therapy for breast cancer: progress and challenges

McCrudden, C. M. & McCarthy, H. O., 10 Nov 2014, In : The application of clinical genetics. 7, p. 209-20 12 p.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
367 Downloads (Pure)

Neuronal differentiation of adipose derived stem cells: Progress so far

Moore, T. J. & Abrahamse, H., 30 Jul 2014, In : International Journal of Photoenergy. 2014, 8 p., 827540.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
125 Downloads (Pure)
2013

Interventions to optimise prescribing for older people in care homes

Alldred, D. P., Raynor, D. K., Hughes, C., Barber, N., Chen, T. F. & Spoor, P., 2013, In : Cochrane database of systematic reviews (Online). 2, 54 p., CD009095.

Research output: Contribution to journalReview article

76 Citations (Scopus)
2012

Connected health care: The future of health care and the role of the pharmacist

Barr, P. J., McElnay, J. C. & Hughes, C. M., 01 Feb 2012, In : Journal of Evaluation in Clinical Practice. 18, 1, p. 56-62 7 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Recent advances in the application of antibodies as therapeutics.

Burden, R. E., Caswell, J., Fay, F. & Scott, C. J., Jan 2012, In : FUTURE MEDICINAL CHEMISTRY. 4, 1, p. 73-86 14 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2005

Costs of pharmacological care of elderly patients

McAlister, D. A., Hughes, C. M., Fleming, I. & O'Neill, C., 01 Feb 2005, In : Reviews in Clinical Gerontology. 14, 1, p. 71-78 8 p.

Research output: Contribution to journalReview article