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2019

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer

Annett, S., Moore, G., Short, A., Marshall, A., McCrudden, C., Yakkundi, A., Das, S., McCluggage, W. G., Nelson, L., Harley, I., Moustafa, N., Kennedy, C. J., deFazio, A., Brand, A., Sharma, R., Brennan, D., O'Toole, S., O'Leary, J., Bates, M., O'Riain, C. & 6 others, O'Connor, D., Furlong, F., McCarthy, H., Kissenpfennig, A., McClements, L. & Robson, T., 27 Nov 2019, In : British Journal of Cancer.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes

Chen, M., Obasanmi, G., Armstrong, D., Lavery, N-J., Kissenpfennig, A., Lois, N. & Xu, H., 08 Jul 2019, In : Journal of neuroinflammation. 16, 1, p. 138

Research output: Contribution to journalArticle

Open Access
File
67 Downloads (Pure)
2018
Open Access
File
7 Citations (Scopus)
251 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
159 Downloads (Pure)
2017

Aspirin reduces lipopolysaccharide induced pulmonary inflammation in human models of ARDS

Hamid, U., Krasnodembskaya, A., Fitzgerald, M., Shyamsundar, M., Kissenpfennig, A., Scott, C., Lefrancais, E., Mark R, L., Verghis, R., Scott, J., Simpson, A. J., McNamee, J., McAuley, D. & O'Kane, C. M., 12 Jan 2017, In : Thorax. 72, p. 971-980 10 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
501 Downloads (Pure)

DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles.

Ali, A. A., McCrudden, C. M., McCaffrey, J., McBride, J. W., Cole, G., Dunne, N. J., Robson, T., Kissenpfennig, A., Donnelly, R. F. & McCarthy, H. O., Apr 2017, In : Nanomedicine: Nanotechnology, Biology and Medicine. 13, 3, p. 921-932 12 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
219 Downloads (Pure)
Open Access
File
24 Citations (Scopus)
264 Downloads (Pure)
Open Access
File
99 Citations (Scopus)
193 Downloads (Pure)

Regulatory T cells promote myelin regeneration in the central nervous system

Dombrowski, Y., O'Hagan, T., Dittmer, M., Penalva, R., Mayoral, S. R., Bankhead, P., Fleville, S., Eleftheriadis, G., Zhao, C., Naughton, M., Hassan, R., Moffat, J., Falconer, J., Boyd, A., Hamilton, P., Allen, I. V., Kissenpfennig, A., Moynagh, P. N., Evergren, E., Perbal, B. & 5 others, Williams, A. C., Ingram, R. J., Chan, J. R., Franklin, R. J. M. & Fitzgerald, D. C., May 2017, In : Nature Neuroscience. 20, 5, p. 674–680 7 p.

Research output: Contribution to journalArticle

Open Access
File
111 Citations (Scopus)
565 Downloads (Pure)
26 Citations (Scopus)
218 Downloads (Pure)
2016

Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

De Majumdar, S., Yu, J., Fookes, M., McAteer, S. P., Llobet, E., Spence, S. F. S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., 11 May 2016, In : PLoS Pathogens. 12, 5, p. e1005649

Research output: Contribution to journalArticle

Open Access
File
172 Downloads (Pure)
Open Access
File
20 Citations (Scopus)
283 Downloads (Pure)
Open Access
File
106 Citations (Scopus)
248 Downloads (Pure)

Reduced epithelial suppressor of cytokine signalling 1 in severe eosinophilic asthma

Doran, E., Choy, D. F., Shikotra, A., Butler, C. A., O'Rourke, D. M., Johnston, J. A., Kissenpfennig, A., Bradding, P., Arron, J. R. & Heaney, L. G., 2016, In : European Respiratory Journal. 48, 3, p. 715-725 11.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
168 Downloads (Pure)

STAT3 activation in circulating monocytes contributes to neovascular age-related macular degeneration

Chen, M., Lechner, J., Zhao, J., Toth, L., Hogg, R., Silvestri, G., Kissenpfennig, A., Chakravarthy, U. & Xu, H., 24 Mar 2016, In : Current Molecular Medicine. 16, 4, p. 412-423 12 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)
2015
Open Access
File
62 Citations (Scopus)
1296 Downloads (Pure)
Open Access
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45 Citations (Scopus)
349 Downloads (Pure)

Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

De Majumdar, S., Yu, J., Fookes, M., McAteer, S. P., Llobet, E., Finn, S., Spence, S., Monahan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., Jan 2015, In : PLoS Pathogens. 11, 1, 22 p., e1004627.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
244 Downloads (Pure)

FKBPL Is a Critical Antiangiogenic Regulator of Developmental and Pathological Angiogenesis

Yakkundi, A., Bennett, R., Hernández-Negrete, I., Delalande, J-M., Hanna, M., Lyubomska, O., Arthur, K., Short, A., McKeen, H., Nelson, L., McCrudden, C. M., McNally, R., McClements, L., McCarthy, H. O., Burns, A. J., Bicknell, R., Kissenpfennig, A. & Robson, T., Apr 2015, In : Arteriosclerosis Thrombosis and Vascular Biology. 35, p. 845-854 10 p.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
160 Downloads (Pure)

Laser-engineered dissolving microneedle arrays for protein delivery: potential for enhanced intradermal vaccination

McCrudden, M. T. C., Torrisi, B. M., Al-Zahrani, S., McCrudden, C. M., Zaric, M., Scott, C. J., Kissenpfennig, A., McCarthy, H. O. & Donnelly, R. F., Mar 2015, In : Journal of Pharmacy and Pharmacology. 67, 3, p. 409-425 17 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation

Spence, S., Greene, M. K., Fay, F., Hams, E., Saunders, S. P., Hamid, U., Fitzgerald, M., Beck, J., Bains, B. K., Smyth, P., Themistou, E., Small, D. M., Schmid, D., O'Kane, C. M., Fitzgerald, D. C., Abdelghany, S. M., Johnston, J. A., Fallon, P. G., Burrows, J. F., McAuley, D. F. & 2 others, Kissenpfennig, A. & Scott, C. J., 02 Sep 2015, In : Science Translational Medicine. 7, 303, 12 p., 140.

Research output: Contribution to journalArticle

Open Access
File
50 Citations (Scopus)
740 Downloads (Pure)
2014

Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis

Linehan, E., Dombrowski, Y., Snoddy, R., Fallon, P. G., Kissenpfennig, A. & Fitzgerald, D. C., Aug 2014, In : Aging cell. 13, 4, p. 699-708

Research output: Contribution to journalArticle

Open Access
File
54 Citations (Scopus)
322 Downloads (Pure)

Btk regulates macrophage polarization in response to lipopolysaccharide

Ní Gabhann, J., Hams, E., Smith, S., Wynne, C., Byrne, J. C., Brennan, K., Spence, S., Kissenpfennig, A., Johnston, J. A., Fallon, P. G. & Jefferies, C. A., 21 Jan 2014, In : PloS one. 9, 1, 11 p., e85834.

Research output: Contribution to journalArticle

Open Access
File
51 Citations (Scopus)
168 Downloads (Pure)

Langerhans cells promote early germinal center formation in response to Leishmania-derived cutaneous antigens

Zimara, N., Florian, C., Schmid, M., Malissen, B., Kissenpfennig, A., Männel, D. N., Edinger, M., Hutchinson, J. A., Hoffmann, P. & Ritter, U., 13 Oct 2014, In : European Journal of Immunology. 44, 10, p. 2955-2967

Research output: Contribution to journalArticle

11 Citations (Scopus)
Open Access
File
24 Citations (Scopus)
219 Downloads (Pure)

SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro

O'Kane, D., Jackson, M. V., Kissenpfennig, A., Spence, S., Damkat-Thomas, L., Tolland, J. P., Smyth, A. E., Denton, C. P., Elborn, J. S., McAuley, D. F. & O'Kane, C. M., Jul 2014, In : Experimental dermatology. 23, 7, p. 497-503 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2013

Cathepsin S from both tumour and tumour-associated cells promote cancer growth and neovascularisation

Small, D. M., Burden, R. E., Jaworski, J., Hegarty, S. M., Spence, S., Burrows, J. F., McFarlane, C., Kissenpfennig, A., McCarthy, H. O., Johnston, J. A., Walker, B. & Scott, C. J., Nov 2013, In : International Journal of Cancer. 133, 9, p. 2102-2112 11 p.

Research output: Contribution to journalArticle

Open Access
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51 Citations (Scopus)
301 Downloads (Pure)

Regulation of Foxp3+ Inducible Regulatory T Cell Stability by SOCS2

Knosp, C. A., Schiering, C., Spence, S., Carroll, H. P., Nel, H. J., Osbourn, M., Jackson, R., Lyubomska, O., Malissen, B., Ingram, R., Fitzgerald, D. C., Powrie, F., Fallon, P. G., Johnston, J. A. & Kissenpfennig, A., 01 Apr 2013, In : Journal of Immunology. 190, 7, p. 3235-3245 8 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-D, L-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses

Zaric, M., Lyubomska, O., Touzelet, O., Poux, C., Al-Zahrani, S., Fay, F., Wallace, L., Terhorst, D., Malissen, B., Henri, S., Power, U. F., Scott, C. J., Donnelly, R. F. & Kissenpfennig, A., 26 Mar 2013, In : ACS Nano. 7, 3, p. 2042-2055 14 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)
1 Downloads (Pure)

Targeting treatment resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway

McClements, L., Yakkundi, A., Papaspyropoulos, A., Harrison, H., Ablett, M. P., Jithesh, P. V., McKeen, H. D., Bennett, R., Donley, C., Kissenpfennig, A., McIntosh, S., McCarthy, H. O., O'Neill, E., Clarke, R. B. & Robson, T., 05 Jun 2013, In : Clinical Cancer Research. 19, 14, p. 3881-3893 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells

Ní Gabhann, J., Spence, S., Wynne, C., Smith, S., Byrne, J. C., Coffey, B., Stacey, K., Kissenpfennig, A., Johnston, J. & Jefferies, C. A., Mar 2012, In : Clinical immunology (Orlando, Fla.). 142, 3, p. 373-82 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin

Wathne, G. J., Kissenpfennig, A., Malissen, B., Zurzolo, C. & Mabbott, N. A., May 2012, In : Journal of Leukocyte Biology. 91, 5, p. 817-28 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Microneedle-mediated vaccine delivery: harnessing cutaneous immunobiology to improve efficacy

Al-Zahrani, S., Zaric, M., McCrudden, C., Scott, C., Kissenpfennig, A. & Donnelly, R. F., May 2012, In : Expert Opinion on Drug Delivery. 9, 5, p. 541-50 10 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses

Flacher, V., Tripp, C. H., Haid, B., Kissenpfennig, A., Malissen, B., Stoitzner, P., Idoyaga, J. & Romani, N., 01 Mar 2012, In : Journal of Immunology. 188, 5, p. 2146-55 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2011

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

Kwok, H. F., Buick, R. J., Kuehn, D., Gormley, J. A., Doherty, D., Jaquin, T. J., McClurg, A., Ward, C., Byrne, T., Jaworski, J., Leung, K. L., Snoddy, P., McAnally, C., Burden, R. E., Gray, B., Lowry, J., Sermadiras, I., Gruszka, N., Courtenay-Luck, N., Kissenpfennig, A. & 3 others, Scott, C. J., Johnston, J. A. & Olwill, S. A., 14 Dec 2011, In : Molecular Cancer. 10, 147.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Cell-to-Cell Interactions and Signals Involved in the Reconstitution of Peripheral CD8(+) T-CM and T-EM Cell Pools

Zaragoza, B., Evaristo, C., Kissenpfennig, A., Libri, V., Malissen, B., Rocha, B., Freitas, A. A. & Almeida, A. R. M., Mar 2011, In : PLoS ONE. 6, 3, e17423.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Langerin(+) Dermal Dendritic Cells Are Critical for CD8(+) T Cell Activation and IgH gamma-1 Class Switching in Response to Gene Gun Vaccines

Stoecklinger, A., Eticha, T. D., Mesdaghi, M., Kissenpfennig, A., Maissen, B., Thalhamer, J. & Hammerl, P., 01 Feb 2011, In : Journal of Immunology. 186, 3, p. 1377-1383 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

Sambasivan, R., Yao, R., Kissenpfennig, A., Van Wittenberghe, L., Paldi, A., Gayraud-Morel, B., Guenou, H., Malissen, B., Tajbakhsh, S. & Galy, A., 01 Sep 2011, In : Development. 138, 19, p. 3647-3656 10 p.

Research output: Contribution to journalArticle

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses

Knosp, C., Carroll, H., Elliott, J., Saunders, S. P., Nel, H. J., Amu, S., Pratt, J., Spence, S., Doran, E., Cooke, N., Jackson, R., Swift, J., Fitzgerald, D., Heaney, L., Fallon, P. G., Kissenpfennig, A. & Johnston, J., 04 Jul 2011, In : Journal of Experimental Medicine. 208, 7, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

The Role of Direct Presentation by Donor Dendritic Cells in Rejection of Minor Histocompatibility Antigen-Mismatched Skin and Hematopoietic Cell Grafts

Fernandes, E., Goold, H. D., Kissenpfennig, A., Malissen, B., Dyson, J. & Bennett, C. L., 27 Jan 2011, In : Transplantation. 91, 2, p. 154-160 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

Development of atopic dermatitis-like inflammation is critically dependent on Langerhans cells in mice.

Elentner, A., Finke, D., Schmuth, M., Chappaz, S., Ebner, S., Malissen, B., Kissenpfennig, A., Romani, N. & Dubrac, S., Feb 2010, In : Experimental dermatology. 19, p. 183-183 1 p.

Research output: Contribution to journalArticle

Foxp3+ T cells induce Perforin-Dependent Dendritic Cell Death in Tumor-Draining Lymph Nodes.

Boissonnas, A., Scholer-Dahirel, A., Simon-Blancal, V., Pace, L., Valet, F., Kissenpfennig, A., Sparwasser, T., Malissen, B., Fetler, L. & Amigorena, S., 26 Feb 2010, In : Immunity. 32, 2, p. 266-278 13 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Langerhans Cells Prime IL-17-Producing T Cells and Dampen Genital Cytotoxic Responses following Mucosal Immunization

Hervouet, C., Luci, C., Rol, N., Rousseau, D., Kissenpfennig, A., Malissen, B., Czerkinsky, C. & Anjuere, F., 01 May 2010, In : Journal of Immunology. 184, 9, p. 4842-4851 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Vasodilator-Stimulated Phosphoprotein Regulates Inside-Out Signaling of beta(2) Integrins in Neutrophils

Deevi, R., Koney-Dash, M., Kissenpfennig, A., Johnston, J. A., Schuh, K., Walter, U. & Dib, K., 15 Jun 2010, In : Journal of Immunology. 184, 12, p. 6575-6584 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2009

Alloantigen-specific de novo-induced Foxp3+ Treg revert in vivo and do not protect from experimental GVHD.

Koenecke, C., Czeloth, N., Bubke, A., Schmitz, S., Kissenpfennig, A., Malissen, B., Huehn, J., Ganser, A., Förster, R. & Prinz, I., Nov 2009, In : European Journal of Immunology. 39(11), 11, p. 3091-3096 6 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)
6 Downloads (Pure)

CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells.

Henri, S., Poulin, L. F., Tamoutounour, S., Ardouin, L., Guilliams, M., De Bovis, B., Devilard, E., Viret, C., Azukiza, H., Kissenpfennig, A. & Malissen, B., 28 Dec 2009, In : Journal of Experimental Medicine. 207, 1, p. 189-206 18 p.

Research output: Contribution to journalArticle

285 Citations (Scopus)

Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network.

Chorro, L., Sarde, A., Li, M., Woollard, K. J., Chambon, P., Malissen, B., Kissenpfennig, A., Barbaroux, J. B., Groves, R. & Geissmann, F., 21 Dec 2009, In : Journal of Experimental Medicine. 206(13), 13, p. 3089-3100 12 p.

Research output: Contribution to journalArticle

244 Citations (Scopus)

Langerhans cells are critical in the development of atopic dermatitis-like inflammation and symptoms in mice

Elentner, A., Finke, D., Schmuth, M., Chappaz, S., Ebner, S., Malissen, B., Kissenpfennig, A., Romani, N. & Dubrac, S., Aug 2009, In : Journal of Cellular and Molecular Medicine. 13, 8 B, p. 2658-2672 15 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

Mingueneau, M., Roncagalli, R., Grégoire, C., Kissenpfennig, A., Miazek, A., Archambaud, C., Wang, Y., Perrin, P., Bertosio, E., Sansoni, A., Richelme, S., Locksley, R. M. & Aguado, E., 21 Aug 2009, In : Immunity. 31(2), 2, p. 197-208 12 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)
9 Downloads (Pure)