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20112021

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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  • Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer

    Crawford, N., Stott, K. J., Sessler, T., McCann, C., McDaid, W., Lees, A., Latimer, C., Fox, J. P., Munck, J. M., Smyth, T., Shah, A., Martins, V., Lawler, M., Dunne, P. D., Kerr, E. M., McDade, S. S., Coyle, V. M. & Longley, D. B., 13 Aug 2021, (Early online date) In: Molecular Cancer Therapeutics.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    15 Downloads (Pure)
  • Dying to Survive—The p53 Paradox

    Lees, A., Sessler, T. & McDade, S., 29 Jun 2021, In: Cancers. 13, 13, 3257.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    File
    62 Downloads (Pure)
  • The pseudo-caspase FLIP(L) regulates cell fate following p53 activation

    Lees, A., McIntyre, A. J., Crawford, N. T., Falcone, F., McCann, C., Holohan, C., Quinn, G. P., Roberts, J. Z., Sessler, T., Gallagher, P. F., Gregg, G. M. A., McAllister, K., McLaughlin, K. M., Allen, W. L., Egan, L. J., Ryan, A. E., Labonte-Wilson, M. J., Dunne, P. D., Wappett, M., Coyle, V. M. & 4 others, Johnston, P. G., Kerr, E. M., Longley, D. B. & McDade, S. S., 28 Jul 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17808–17819

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    7 Citations (Scopus)
    14 Downloads (Pure)
  • Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

    Mencacci, N. E., Isaias, I. U., Reich, M. M., Ganos, C., Plagnol, V., Polke, J. M., Bras, J., Hersheson, J., Stamelou, M., Pittman, A. M., Noyce, A. J., Mok, K. Y., Opladen, T., Kunstmann, E., Hodecker, S., Munchau, A., Volkmann, J., Samnick, S., Sidle, K., Nanji, T. & 26 others, Sweeney, M. G., Houlden, H., Batla, A., Zecchinelli, A. L., Pezzoli, G., Marotta, G., Lees, A., Alegria, P., Krack, P., Cormier-Dequaire, F., Lesage, S., Brice, A., Heutink, P., Gasser, T., Lubbe, S. J., Morris, H. R., Taba, P., Koks, S., Majounie, E., Raphael Gibbs, J., Singleton, A., Hardy, J., Klebe, S., Bhatia, K. P., Wood, N. W. & Morrison, K., 01 Sep 2014, In: Brain. 137, 9, p. 2480-2492 13 p.

    Research output: Contribution to journalArticlepeer-review

    115 Citations (Scopus)
  • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

    Beilina, A., Rudenko, I. N., Kaganovich, A., Civiero, L., Chau, H., Kalia, S. K., Kalia, L. V., Lobbestael, E., Chia, R., Ndukwe, K., Ding, J., Nalls, M. A., Olszewski, M., Hauser, D. N., Kumaran, R., Lozano, A. M., Baekelandt, V., Greene, L. E., Taymans, J-M., Greggio, E. & 136 others, Cookson, M. R., Plagnol, V., Martinez, M., Hernandez, D. G., Sharma, M., Sheerin, U-M., Saad, M., Simon-Sanchez, J., Schulte, C., Lesage, S., Sveinbjornsdottir, S., Arepalli, S., Barker, R., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chong, S., Clarke, C. E., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J-F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Durr, A., Edkins, S., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Gustafsson, O., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Munchen, H. Z., Jonsson, P. V., Lambert, J-C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Mudanohwo, E., O'Sullivan, S. S., Pearson, J., Perlmutter, J. S., Petursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., Smith, C., Spencer, C. C. A., Stefansson, H., Steinberg, S., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Vidailhet, M., Walker, R., van de Warrenburg, B., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefansson, K., Hardy, J., Heutink, P., Brice, A., Gasser, T., Singleton, A. B., Wood, N. W., Chinnery, P. F., Ferrucci, L., Johnson, R., Longo, D. L., Majounie, E., O'Brien, R., Troncoso, J., van der Brug, M., Zielke, H. R. & Zonderman, A. B., 18 Feb 2014, In: Proceedings of the National Academy of Sciences. 111, 7, p. 2626-2631 6 p.

    Research output: Contribution to journalArticlepeer-review

    237 Citations (Scopus)