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Dive into the research topics where Andrea Lees is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Nanoencapsulation of MDM2 inhibitor RG7388 and class-I HDAC inhibitor entinostat enhances their therapeutic potential through synergistic antitumor effects and reduction of systemic toxicity
Abed, A., Greene, M. K., Alsa'd, A. A., Lees, A., Hindley, A., Longley, D. B., McDade, S. S. & Scott, C. J., 04 Mar 2024, In: Molecular Pharmaceutics. 21, 3, p. 1246–1255 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Link opens in a new tab Citations (Scopus)76 Downloads (Pure) -
Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
Grinkevich, V., Wappett, M., Crawford, N., Price, S., Lees, A., McCann, C., McAllister, K. A., Prehn, J. H., Young, J., Bateson, J. H., Gallagher, L., Michaut, M., Iyer, V., Chatzipli, A., Barthorpe, S., Ciznadija, D., Sloma, I., Wesa, A., Tice, D. A. & Wessels, L. F. A. & 4 others, , 01 Apr 2022, In: Molecular Cancer Therapeutics. 21, 4, p. 594-606Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Link opens in a new tab Citations (Scopus)127 Downloads (Pure) -
Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer
Crawford, N., Stott, K. J., Sessler, T., McCann, C., McDaid, W., Lees, A., Latimer, C., Fox, J. P., Munck, J. M., Smyth, T., Shah, A., Martins, V., Lawler, M., Dunne, P. D., Kerr, E. M., McDade, S. S., Coyle, V. M. & Longley, D. B., Sept 2021, In: Molecular Cancer Therapeutics. 20, 9, p. 1627-1639 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Link opens in a new tab Citations (Scopus)272 Downloads (Pure) -
Dying to Survive—The p53 Paradox
Lees, A., Sessler, T. & McDade, S., 29 Jun 2021, In: Cancers. 13, 13, 3257.Research output: Contribution to journal › Review article › peer-review
Open AccessFile27 Link opens in a new tab Citations (Scopus)433 Downloads (Pure) -
The pseudo-caspase FLIP(L) regulates cell fate following p53 activation
Lees, A., McIntyre, A. J., Crawford, N. T., Falcone, F., McCann, C., Holohan, C., Quinn, G. P., Roberts, J. Z., Sessler, T., Gallagher, P. F., Gregg, G. M. A., McAllister, K., McLaughlin, K. M., Allen, W. L., Egan, L. J., Ryan, A. E., Labonte-Wilson, M. J., Dunne, P. D., Wappett, M. & Coyle, V. M. & 4 others, , 28 Jul 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17808–17819Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Link opens in a new tab Citations (Scopus)185 Downloads (Pure)
Thesis
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Delineating mechanisms which underlie differential cell fates induced by p53 activation and HDAC inhibition in colorectal cancer
Lees, A. (Author), McDade, S. (Supervisor) & Longley, D. (Supervisor), Dec 2021Student thesis: Doctoral Thesis › Doctor of Philosophy
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