If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Andrew Young is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
asparaginylendopeptidase Medicine & Life Sciences
cathepsin S Medicine & Life Sciences
Interferon Regulatory Factor-3 Medicine & Life Sciences
TCF Transcription Factors Medicine & Life Sciences
Carbamates Medicine & Life Sciences
Autoimmune Experimental Encephalomyelitis Medicine & Life Sciences
Oligodendroglia Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2014 2018

2 Citations (Scopus)
207 Downloads (Pure)

Characterization of a murine mixed neuron-glia model and cellular responses to regulatory T cell-derived factors

Dittmer, M., Young, A., O'Hagan, T., Eleftheriadis, G., Bankhead, P., Dombrowski, Y., Medina, R. J. & Fitzgerald, D. C., 02 May 2018, In : Molecular Brain. 11, 1, p. 1-25

Research output: Contribution to journalArticle

Open Access
File
TCF Transcription Factors
Oligodendroglia
Regulatory T-Lymphocytes
Neuroglia
Neurons

CCL2 is transcriptionally controlled by the lysosomal protease cathepsin S in a CD74-dependent manner

Wilkinson, R., Magorrian, S., Williams, R., Young, A., Small, D., Scott, C. & Burden, R., 22 Aug 2015, In : Oncotarget. p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
protease S
Neoplasms
Tumor Microenvironment
6 Citations (Scopus)

Development of a potent and selective cell penetrant Legumain inhibitor

Ness, K. A., Eddie, S. L., Higgins, C. A., Templeman, A., D'Costa, Z., Gaddale, K. K. D., Bouzzaoui, S., Jordan, L., Janssen, D., Harrison, T., Burkamp, F., Young, A., Burden, R., Scott, C. J., Mullan, P. B. & Williams, R., 01 Dec 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 23, p. 5642-5645

Research output: Contribution to journalLetter

asparaginylendopeptidase
Assays
Cell Survival
Cells
Molecules
19 Citations (Scopus)

Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis.

Fitzgerald, D., O'Brien, K., Young, A., Fonseca-Kelly, Z., Rostami, A. & Gran, B., 28 Jul 2014, In : Journal of neuroinflammation. 11, 130

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Autoimmune Experimental Encephalomyelitis
Th17 Cells
Th1 Cells
Interferon-beta
4 Citations (Scopus)

P3 SAR exploration of biphenyl carbamate based Legumain inhibitors

Higgins, C., Bouazzaoui, S., Gaddale Devanna, K., D'Costa, Z., Templeman, A., O'Rourke, M., Young, A., Scott, C., Harrison, T., Mullan, P. & Williams, R., 01 Jun 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 11, p. 2521-2524

Research output: Contribution to journalArticle

asparaginylendopeptidase
Carbamates
Enzymes
diphenyl