• Room 02.059 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Dr Krasnodembskaya is open to PhD applications from motivated and enthusiastic students who is interested in Mesenchymal Stem Cells biology and therapeutic applications in lung diseases. Potential PhD projects on the following topics are available (the list is not exhaustive) : Investigation of the role of MSC exosomal miRNAs in epithelial and endothelial repair in ARDS The role of MSC mitochondrial transfer in lung regeneration The role of apoptosis in MSC therapeutic effects in ARDS

20042020

Research output per year

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Research Output

2020

Emerging Therapeutic Potential of Mesenchymal Stem/Stromal Cells in Preeclampsia

Suvakov, S., Richards, C., Nikolic, V., Simic, T. P., McGrath, K., Krasnodembskaya, A. & McClements, L., 14 Apr 2020, In : Current Hypertension Reports. 22, 37.

Research output: Contribution to journalArticle

In reply

Krasnodembskaya, A., 22 Apr 2020, In : Stem cells translational medicine.

Research output: Contribution to journalArticle

Open Access
File
4 Downloads (Pure)
2019
Open Access
File
6 Citations (Scopus)
153 Downloads (Pure)

Intercellular Communication via Organelle Transfer in the Biology and Therapeutic Applications of Stem Cells

Murray, L. MA. & Krasnodembskaya, A. D., 01 Jan 2019, In : Stem Cells. 37, 1, p. 14-25

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
157 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
57 Downloads (Pure)

The Necrobiology of Mesenchymal Stromal Cells Affects Therapeutic Efficacy

Weiss, D. J., English, K., Krasnodembskaya, A., Isaza-Correa, J. M., Hawthorne, J. J. & Mahon, B. P., 04 Jun 2019, In : Frontiers in immunology. 10, 12 p., 1228.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
102 Downloads (Pure)
2018

Mesenchymal Stem Cells influence trophoblast and endothelial cell functionality important for prevention of pre-eclampsia via a novel anti-angiogenic protein, FKBPL

Todd, N., McNally, R., Alqudah, A., Krasnodembskaya, A. & McClements, L., Jun 2018, In : Journal of Hypertension. 36, eSupplement 1, p. e154

Research output: Contribution to journalMeeting abstract

The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Murine E. coli Pneumonia

Gupta, N., Sinha, R., Krasnodembskaya, A., Xu, X., Nizet, V., Matthay, MA. & Griffin, G., 01 May 2018, In : Stem Cells. 36, 5, p. 796-806 11 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
144 Downloads (Pure)
2017
Open Access
File
334 Downloads (Pure)

Aspirin reduces lipopolysaccharide induced pulmonary inflammation in human models of ARDS

Hamid, U., Krasnodembskaya, A., Fitzgerald, M., Shyamsundar, M., Kissenpfennig, A., Scott, C., Lefrancais, E., Mark R, L., Verghis, R., Scott, J., Simpson, A. J., McNamee, J., McAuley, D. & O'Kane, C. M., 12 Jan 2017, In : Thorax. 72, p. 971-980 10 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
499 Downloads (Pure)

Hypercapnia impairs the ability of mesenchymal stem cells to promote distal lung epithelial wound repair in ards

Fergie, N., McAuley, D., O'Kane, C. & Krasnodembskaya, A., 15 Nov 2017, In : Thorax. 72, A108, p. 1 1 p., P47 .

Research output: Contribution to journalMeeting abstract

8 Citations (Scopus)
Open Access
File
99 Citations (Scopus)
193 Downloads (Pure)
Open Access
File
106 Citations (Scopus)
245 Downloads (Pure)

Human Mesenchymal Stromal Cell (hMSC) regulation of human macrophages in in vitro models of the Acute Respiratory Distress Syndrome (ARDS)

Morrison, T., Jackson, M., Kissenpfennig, A., O'Kane, C., McAuley, D. & Krasnodembskaya, A., 01 Dec 2015, In : Thorax. 70, Suppl 3, 1 p., A38.

Research output: Contribution to journalMeeting abstract

Interaction of arenicin-1 with C1q protein

Berlov, M. N., Umnyakova, E. S., Leonova, T. S., Milman, B. L., Krasnodembskaya, A. D., Ovchinnikova, T. V. & Kokryakov, V. N., 01 Nov 2015, In : Russian Journal of Bioorganic Chemistry. 41, 6, p. 597-601

Research output: Contribution to journalArticle

4 Citations (Scopus)

Interaction of arenicin-1 with C1q protein. Article in Russian.

Berlov, M. N., Umnyakova, E. S., Leonova, T. S., Milman, B. L., Krasnodembskaya, A. D., Ovchinnikova, T. V. & Kokryakov, V. N., 01 Nov 2015, In : BIOORGANICHESKAYA KHIMIYA. 41, 6, p. 664-668 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
File
3 Citations (Scopus)
254 Downloads (Pure)

Erratum: Human mesenchymal stem cells moderate alveolar macrophage polarisation in vivo and in vitro.

Krasnodembskaya, A., Morrison, T., O'Kane, C., McAuley, D. F. & Matthay, M. A., 01 Mar 2014, In : Thorax. 69, 3, 1 p., A22.

Research output: Contribution to journalComment/debate

Open Access

Expression pattern of arenicins - the antimicrobial peptides of polychaete Arenicola marina

Maltseva, A., Kotenko, O., Kokryakov, V., Starunov, I. & Krasnodembskaya, A., 19 Dec 2014, In : Frontiers in Physiology. 120063.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
350 Downloads (Pure)

Human mesenchymal stem cells (MSC) modulate alveolar macrophage polarization in vivo and in vitro.

Krasnodembskaya, A., Morrison, T., O'Kane, C., McAuley, D. & Matthay, M., 01 Sep 2014, In : European Respiratory Journal. 44, Suppl 58, 1 p., 3427.

Research output: Contribution to journalMeeting abstract

2013

British Thoracic Society winter meeting 2013. Human Mesenchymal Stem Cells modulate alveolar macrophage polarization in vivo and in vitro.

Krasnodembskaya, A., Morrison, T., O'Kane, C. & McAuley, D., 2013, In : Thorax. 68, Suppl 3, p. Suppl 3 A22 1 p.

Research output: Contribution to journalMeeting abstract

Mesenchymal Stem Cells for Treatment of Acute Lung Injury. Mesenchymal stromal cells: Basic Biology & Clinical Applications

Serikov, V., Krasnodembskaya, A., Lee, J-W., Eldridge, M. & Matthay, M. A., 2013, Mesenchymal stromal cells: Basic Biology & Clinical Applications. Hematti, Peiman, Keating & Armand (eds.). Springer, p. 561-570 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Therapeutic Effects of Human Mesenchymal Stem Cells in Ex Vivo Human Lungs Injured with Live Bacteria

Lee, J. W., Krasnodembskaya, A., McKenna, D. H., Song, Y., Abbott, J. & Matthay, M. A., 01 Apr 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 7, p. 751-60 10 p.

Research output: Contribution to journalArticle

Open Access
File
163 Citations (Scopus)
136 Downloads (Pure)

Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes

Krasnodembskaya, A., Samarani, G., Song, Y., Zhuo, H., Su, X., Lee, J-W., Gupta, N., Petrini, M. & Matthay, M. A., 15 May 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 302, 10, p. L1003-L1013 L1003-L1013.

Research output: Contribution to journalArticle

174 Citations (Scopus)

Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia

Gupta, N., Krasnodembskaya, A., Kapetanaki, M., Mouded, M., Tan, X., Serikov, V. & Matthay, M. A., Jun 2012, In : Thorax. 67, 6, p. 533-539 7 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)

Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factor

Lee, J. W., Fang, X., Krasnodembskaya, A., Howard, J. P. & Matthay, M. A., Jun 2011, In : Stem Cells. 29, 6, p. 913-919 7 p.

Research output: Contribution to journalArticle

Open Access
File
234 Citations (Scopus)
132 Downloads (Pure)
2010

Antibacterial Effect of Human Mesenchymal Stem Cells is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37

Krasnodembskaya, A., Song, Y., Fang, X., Gupta, N., Serikov, V., Lee, J-W. & Matthay, M. A., 30 Dec 2010, In : Stem Cells. 28, 12, p. 2229-2238 10 p.

Research output: Contribution to journalArticle

362 Citations (Scopus)
2008

Bone marrow-derived cells participate in stromal remodeling of the lung following acute bacterial pneumonia in mice

Serikov, V. B., Mikhaylov, V. M., Krasnodembskaya, A. & Matthay, M. A., Jun 2008, In : Lung. 186, 3, p. 179-190 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Peroxiredoxin V contributes to antioxidant defense of lung epithelial cells

Avila, P. C., Kropotov, A. V., Krutilina, R., Krasnodembskaya, A., Tomilin, N. V. & Serikov, V. B., Apr 2008, In : Lung. 186, 2, p. 103-114 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Structure and mode of action of the antimicrobial peptide arenicin

Andrä, J., Jakovkin, I., Grötzinger, J., Hecht, O., Krasnodembskaya, A., Goldmann, T., Gutsmann, T. & Leippe, M., 15 Feb 2008, In : Biochemical Journal. 410, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
2005

Peptides Arenicins isolated from sea annelid worm Arenicola marina eliciting antibacterial effect.

Translated title of the contribution: Peptides Arenicins isolated from sea annelid worm Arenicola marina eliciting antibacterial effect.Krasnodembskaya, A., Ovchinnikova, T., Aleshina, G., Balandin, S., Markelov, M. & Kokryakov, V., 25 Oct 2005

Research output: Patent

2004

Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina

Ovchinnikova, T. V., Aleshina, G. M., Balandin, S. V., Krasnodembskaya, A., Markelov, M. L., Frolova, E. I., Leonova, Y. F., Tagaev, A. A., Krasnodembsky, E. G. & Kokryakov, V. N., 05 Nov 2004, In : FEBS Letters. 577, 1-2, p. 209-214 6 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)