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Personal profile

Research Statement

My research interests are in molecular genetics of common complex disorders. My aims are to understand the genetic and environmental factors that contribute to risk of disease so that those at highest risk can be identified in time for treatment or lifestyle changes to prevent disease.

I am also developing an interest in how microRNAs regulate genes, and to assess their potential as biomarkers of disease.

Fingerprint Dive into the research topics where Anne Hughes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 20 Similar Profiles
Complement Factor H Medicine & Life Sciences
Macular Degeneration Medicine & Life Sciences
Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Abdominal Aortic Aneurysm Medicine & Life Sciences
Haplotypes Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Population Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1997 2018

1 Citation (Scopus)

Automated quantification of retinal vessel morphometry in the UK biobank cohort

on behalf of the UK Biobank Eye and Vision Consortium, 12 Mar 2018, Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications (IPTA 2017). Institute of Electrical and Electronics Engineers Inc., 6 p. (International Conference on Image Processing Theory, Tools and Applications (IPTA): Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Retinal Vessels
Image analysis
Epidemiologic Studies
19 Citations (Scopus)

Abdominal Aortic Aneurysm Genetic Associations: Mostly False? A Systematic Review and Meta-analysis

Bradley, D. T., Badger, S. A., McFarland, M. & Hughes, A. E., Jan 2016, In : European Journal of Vascular Endovascular Surgery. 51, 1, p. 64-75 12 p.

Research output: Contribution to journalArticle

Open Access
Abdominal Aortic Aneurysm
Genetic Polymorphisms
Information Storage and Retrieval
23 Citations (Scopus)

Automated retinal image quality assessment on the UK Biobank dataset for epidemiological studies

UK Biobank Eye and Vision Consortium, 01 Apr 2016, In : Computers in Biology and Medicine. 71, p. 67-76 10 p.

Research output: Contribution to journalArticle

Image quality
Epidemiologic Studies
Retinal Vessels
32 Citations (Scopus)

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., Strauss, E., van 't Hof, F. N., Webb, T., Erdman, R., Ritchie, M. D., Elmore, J. R., Verma, A., Pendergrass, S., Kullo, I. J., Ye, Z., Peissig, P. L., Gottesman, O., Verma, S. S., Malinowski, J. & 97 othersRasmussen-Torvik, L. J., Borthwick, K., Smelser, D. T., Crosslin, D. R., de Andrade, M., Ryer, E. J., McCarty, C. A., Bottinger, E. P., Pacheco, J. A., Crawford, D. C., Carrell, D. S., Gerhard, G. S., Franklin, D. P., Carey, D. J., Phillips, V. L., Williams, M. J., Wei, W., Blair, R., Hill, A. A., Vasudevan, T. M., Lewis, D. R., Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., Oszkinis, G., Galora, S., Saracini, C., Abbate, R., Pulli, R., Pratesi, C., Saratzis, A., Verissimo, A., Bumpstead, S. J., Badger, S. A., Clough, R. E., Cockerill, G. W., Hafez, H., Scott, D. J., Futers, T. S., Romaine, S. P., Bridge, K., Griffin, K. J., Bailey, M. A., Smith, A., Thompson, M. M., van Bockxmeer, F., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Lindholt, J. S., Hughes, A. E., Bradley, D. T., Stirrups, K., Golledge, J., Norman, P. E., Powell, J. T., Humphries, S. E., Hamby, S. E., Goodall, A. H., Nelson, C. P., Sakalihasan, N., Courtois, A., Ferrell, R. E., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Eicher, J. D., Johnson, A. D., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E., Björkegren, J. L., Lipovich, L., Drolet, A. M., Verhoeven, E., Zeebregts, C. J., Geelkerken, R. H., van Sambeek, M. R., van Sterkenburg, S. M., de Vries, J-P. P., Stefansson, K., Thompson, J. R., de Bakker, P. I., Deloukas, P., Sayers, R. D., Harrison, S., van Rij, A. M., Samani, N. J. & Bown, M. J., 29 Nov 2016, In : Circulation Research.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Abdominal Aortic Aneurysm
Validation Studies
Risk Management
6 Citations (Scopus)

Rare CFH mutations and early-onset age-related macular degeneration

Hughes, A. E., Meng, W., Bridgett, S. & Bradley, D. T., 20 Apr 2016, In : Acta Ophthalmologica. 94, 3, p. e247-e248 2 p.

Research output: Contribution to journalLetter


Identifying Patients with Rare Forms of Erythrocytosis

Mary Frances McMullin (Participant), Terence Lappin (Participant), Anne Hughes (Participant)

Impact: Health Impact, Quality of Life Impact