• Room 03.019 - WWIEM Block 6 MBC Site

    United Kingdom

Willing to speak to media

20082019
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Personal profile

Research Statement

The overarching aim of my research is to understand the lymphocytic response to bacterial infections, in order to facilitate rational vaccine design. I have a particular interest in the interface between innate and adaptive lymphocytic cell responses.  We use a combination of approaches to elucidate the lymphocytic responses to bacterial infection, including in vitro models and analysis of clinical samples, but the greatest area of expertise within my lab is the use of in vivo murine bacterial infection models.  There are a number of ongoing projects within the lab, these include;

(i) The induction of innate immunological memory against bacterial infection.

(ii) Identification of bacterial (Pseudomonas and Anthrax) antigens that elicit a memory T cell response and may therefore represent novel vaccine candidates

(iii) Defining the role of T cells in driving and resolving inflammation (Streptococcus and Pseudomonas)

(iv) The rational design and optimisation of pre-clinical models to test novel antimicrobials and investigate host-pathogen interactions. 

Fingerprint Dive into the research topics where Beckie Ingram is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2018

Selected Research Output 2008 2019

26 Citations (Scopus)

Natural Exposure to Cutaneous Anthrax Gives Long-Lasting T Cell Immunity Encompassing Infection-Specific Epitopes

Ingram, R., Metan, G., Maillere, B., Doganay, M., Ozkul, Y., Kim, L. U., Baillie, L., Dyson, H., Williamson, E. D., Chu, K. K., Ascough, S., Moore, S., Huwar, T. B., Robinson, J. H., Sriskandan, S. & Altmann, D. M., 01 Apr 2010, In : Journal of Immunology. 184, 7, p. 3814-3821 8 p.

Research output: Contribution to journalArticle

Anthrax
Epitopes
Immunity
T-Lymphocytes
Bacterial Infections
12 Citations (Scopus)

Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell Immunity

Ascough, S., Ingram, R. J., Chu, K. K., Reynolds, C. J., Musson, J. A., Doganay, M., Metan, G., Ozkul, Y., Baillie, L., Sriskandan, S., Moore, S. J., Gallagher, T. B., Dyson, H., Williamson, E. D., Robinson, J. H., Maillere, B., Boyton, R. J. & Altmann, D. M., May 2014, In : PLoS Pathogens. 10, 5, 17 p., e1004085.

Research output: Contribution to journalArticle

Open Access
File
Transgenic Mice
Immunity
Epitopes
T-Lymphocytes
Immunodominant Epitopes
80 Citations (Scopus)
Open Access
File
Pseudomonas Infections
Gentamicins
Nanoparticles
Pseudomonas aeruginosa
Hydrophilicity
49 Citations (Scopus)

Keratinocyte Growth-Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury

Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S., Calfee, C. S., Matthay, M. A. & O'Kane, C. M., 15 Jun 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 12, p. 1520-1529 10 p.

Research output: Contribution to journalArticle

Open Access
Fibroblast Growth Factor 7
Lung Injury
Bronchoalveolar Lavage
Survival
Adult Respiratory Distress Syndrome

Prizes

Immunology Research Prize

Rebecca Ingram (Recipient), 01 Aug 2015

Prize: Prize (including medals and awards)

New Investigator Award

Rebecca Ingram (Recipient), 01 Aug 2011

Prize: Prize (including medals and awards)

Poster Prize

Rebecca Ingram (Recipient), 2012

Prize: Prize (including medals and awards)

honors and awards

Prize - Best Poster

Rebecca Ingram (Recipient), 20 Mar 2015

Prize: Prize (including medals and awards)

Activities 2006 2016

Invited talk - The yin and yang of innate lymphoid cells

Beckie Ingram (Speaker)
09 Feb 2016

Activity: Talk or presentation typesInvited talk

Invited talk - Innate lymphoid cell memory

Beckie Ingram (Speaker)
18 Feb 2016

Activity: Talk or presentation typesInvited talk

Anthrax Workshop, National Centre for Disease Control and Public Health

Beckie Ingram (Invited speaker)
2015

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Journal of visualized experiments : JoVE (Journal)

Beckie Ingram (Peer reviewer)
2015 → …

Activity: Publication peer-review and editorial work typesPublication peer-review

Infection and Immunity (Journal)

Beckie Ingram (Peer reviewer)
2015 → …

Activity: Publication peer-review and editorial work typesEditorial activity