• Room 03.019 - Clinical Science B

    United Kingdom

Accepting PhD Students

PhD projects

Dr McGuinness is open to wide ranging PhD applications from candidates with both a clinical and science background. Her fields of interest include:
The role of inflammation in dementia
The role of diet in cognitive decline
Clinical trials in Alzheimer's disease and mild cognitive impairment
Cognitive impairment in longitudinal studies
Previous research experience is desirable.

20022025

Research activity per year

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Search results

  • 2017

    Serum concentrations of vitamin E and carotenoids are altered in Alzheimer's disease: a case control study

    Mullan, K., Williams, M., Cardwell, C., McGuinness, B., Passmore, A., Silvestri, G., Woodside, J. & McKay, G., 01 Sept 2017, (Early online date) In: Alzheimer's & Dementia: Translational Research and Clinical Interventions. 3, 3, p. 432 -439

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    60 Citations (Scopus)
    300 Downloads (Pure)
  • 2016

    ABCA7 p.G215S as potential protective factor for Alzheimer's disease

    Sassi, C., Nalls, M. A., Ridge, P. G., Gibbs, J. R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M. R., Passmore, P., Craig, D., Johnston, J. & McGuinness, B. & 30 others, Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Mann, D. M., Pickering-Brown, S., Brown, K. S., Lowe, J., Morgan, K., Smith, A. D., Wilcock, G., Warden, D., Holmes, C., Holstege, H., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Van Swieten, J. C., Santana, I., Oliveira, C., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Goate, A. M., Singleton, A. B., Guerreiro, R. & Hardy, J., 01 Oct 2016, In: Neurobiology of Aging. 46, p. 235.e1-235.e9

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    45 Citations (Scopus)
    215 Downloads (Pure)
  • Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

    Pan, X., Bin Nasaruddin, M., Elliott, C. T., McGuinness, B., Passmore, A. P., Kehoe, P. G., Holscher, C., McClean, P. L., Graham, S. F. & Green, B. D., Feb 2016, In: Neurobiology of Aging. 38, p. 151-163 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    98 Citations (Scopus)
    728 Downloads (Pure)
  • A novel Alzheimer disease locus located near the gene encoding tau protein

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L. & Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., 01 Jan 2016, In: Molecular Psychiatry. 21, p. 108-117 10 p.

    Research output: Contribution to journalArticlepeer-review

    192 Citations (Scopus)
  • A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol

    Greenan, C., Murphy, L., Yu, L.-M., Kehoe, P. G., Coulthard, E., Bath, P., Stewart, R., Jones, R., Corbett, A., Thomas, A., Connelly, P., Arrojo, F., Canning, R., Wallach, S., Henderson, C., McGuinness, B., O'Sullivan, M., Holmes, C., Knapp, M. & Ballard, C. & 2 others, Passmore, P. & AFFECT Investigators, 18 Jul 2016, (Early online date) In: Trials. 17, 324, 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    4 Citations (Scopus)
    229 Downloads (Pure)
  • 55 Citations (Scopus)
  • Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s Disease

    Sassi, C., Ridge, P. G., Nalls, M. A., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Lord, J., Turton, J., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Bras, J., Goate, A. M. & Singleton, A. B. & 18 others, Guerreiro, R., Hardy, J., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Mann, D. M., Lowe, J., David Smith, A., Wilcock, G., Warden, D. & Holmes, C., 01 Jun 2016, In: PLoS ONE. 11, 6, e0150079.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    28 Citations (Scopus)
    274 Downloads (Pure)
  • Platelet membrane ß-secretase activity in mild cognitive impairment and conversion to dementia: a longitudinal study.

    McGuinness, B., Fuchs, M., Barrett, S. L., Passmore, A. P. & Johnston, J. A., 01 Oct 2016, In: JAD: Journal of Alzheimer's Disease. 49, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    11 Citations (Scopus)
    251 Downloads (Pure)
  • Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

    Barber, I. S., Garc??a-C??rdenas, J. M., Sakdapanichkul, C., Deacon, C., Zapata Erazo, G., Guerreiro, R., Bras, J., Hernandez, D., Singleton, A. B., Guetta-Baranes, T., Braae, A., Clement, N., Patel, T., Brookes, K., Medway, C., Chappell, S., Mann, D. M., Passmore, P., Craig, D. & Johnston, J. & 19 others, McGuinness, B., Todd, S., Heun, R., Kolsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Pickering-Brown, S., Snowden, J., Richardson, A., Jones, M., Neary, D., Harris, J., Lowe, J., Smith, A. D., Wilcock, G., Warden, D., Holmes, C. & Morgan, K., 01 Mar 2016, In: Neurobiology of Aging. 39, p. 220.e1-220.e7 7 p.

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)
  • Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.

    Traylor, M., Adib-Samii, P., Harold, D., Alzheimer's Disease Neuroimaging Initiative, T. A. D. N., International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource, T. I. S. G. C., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., METASTROKE, H. S., International Genomics of Alzheimer's Project (IGAP), investigators, A. T. M. A. I. G. O. A. P., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J. & Boncoraglio, G. & 155 others, Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A., Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., de Bakker, P. I. W., Lambert, J.-C., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., DeStefano, A. L., Bis, J. C., Beecham, G. W., Grenier‐Boley, B., Russo, G., Thornton‐Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M., Choi, S.-H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., Jager, P. L. D., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K. S., Kamboh, M. I., Keller, L., Barberger‐Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., George‐Hyslop, P. S., Clarimon, J., Lleo, A., Bayer, A. J., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez‐Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F. E., (EADI), E. A. D. I., (GERAD), G. A. E. R. I. A. D., (ADGC), A. D. G. C., (CHARGE), C. F. H. A. A. R. I. G. E., Moebus, S., Mecocci, P., Zompo, M. D., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton‐Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S. & Mosley, T. H., 23 Feb 2016, In: Annals of neurology. p. 739 1 p.

    Research output: Contribution to journalArticlepeer-review

    53 Citations (Scopus)
  • Statin withdrawal in people with dementia

    Passmore, A., McGuinness, B. & Cardwell, C., 09 Sept 2016, (Early online date) In: Cochrane database of systematic reviews (Online). 9

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    8 Citations (Scopus)
    408 Downloads (Pure)
  • 2015

    Aspirin and anti-inflammatory drugs for the prevention of dementia

    Jordan, F., McGuinness, B., Murphy, K., Passmore, P., Kelly, J. P. & Devane, D., 08 Jan 2015, In: Cochrane Database of Systematic Reviews. 2015, 1, p. 1-12

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    12 Citations (Scopus)
    519 Downloads (Pure)
  • Associations between potentially modifiable risk factors and Alzheimer disease: a Mendelian randomization study

    Østergaard, S. D., Mukherjee, S., Sharp, S. J., Proitsi, P., Lotta, L. A., Day, F., Perry, J. R. B., Boehme, K. L., Walter, S., Kauwe, J. S. K., Gibbons, L. E., Larson, E. B., Powell, J. F., Langenberg, C., Crane, P. K., Wareham, N. J., Scott, R. A., Albert, M. S., Albin, R. L. & Apostolova, L. G. & 281 others, Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barber, R. C., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Farrer, L. A., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Goate, A., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Haines, J. L., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., Mayeux, R., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Pericak-Vance, M. A., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Sano, M., Schellenberg, G. D., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., St George-Hyslop, P., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., VanDeerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Chapman, J., Russo, G., Hamshere, M., Singh Pahwa, J., Escott-Price, V., Badarinarayan, N., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Taylor, S., Lovestone, S., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., McGuinness, B., Todd, S., Johnston, J., Holmes, C., Mann, D., David Smith, A., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Nowotny, P., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Shane Pankratz, V., Holmans, P., Donovan, M. O., Owen, M. J., Williams, J., Forouhi, N. G., Kerrison, N. D., Sims, M., Lucarelli, D. M. E., Barroso, I., McCarthy, M. I., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Franks, P. W., Gonzalez, C., Grioni, S., Kaaks, R., Key, T. J., Navarro, C., Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Ramón Quirós, J., Rolandsson, O., Sacerdote, C., Sánchez, M. J., Slimani, N., Tjonneland, A., Tumino, R., van der Daphne, A. L., van der Schouw, Y. T. & Riboli, E., 16 Jun 2015, In: PLoS Medicine. 12, 6, e1001841.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    148 Citations (Scopus)
    8 Downloads (Pure)
  • Blood type gene locus has no influence on ACE association with Alzheimer's disease

    Braae, A., Medway, C., Carrasquillo, M., Younkin, S., Alzheimer's Research UK (ARUK) Consortium, Kehoe, P. G., Morgan, K., Passmore, P., Craig, D., Johnston, J. & McGuinness, B., 01 Apr 2015, In: Neurobiology of Aging. 36, 4, p. 1767.e1-1767.e2

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)
  • Convergent genetic and expression data implicate immunity in Alzheimer's disease

    Jones, L., Lambert, J.-C., Wang, L.-S., Choi, S.-H., Harold, D., Vedernikov, A., Escott-Price, V., Stone, T., Richards, A., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Gerrish, A., Craig, D., Johnston, J. A., McGuinness, B., Todd, S. & Passmore, P., Jun 2015, In: Alzheimers & dementia. 11, 6, p. 658-671 14 p.

    Research output: Contribution to journalArticlepeer-review

    161 Citations (Scopus)
  • Dementia

    Cunningham, E. L., McGuinness, B., Herron, B. & Passmore, A. P., May 2015, In: Ulster Medical Journal. 84, 2, p. 79-87

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    126 Citations (Scopus)
    168 Downloads (Pure)
  • Open Access
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    26 Citations (Scopus)
    421 Downloads (Pure)
  • Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

    the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, 19 May 2015, In: Cell Reports. 11, 7, p. 1134-1146 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    81 Citations (Scopus)
  • Quantitative Measurement of [Na+] and [K+] in Postmortem Human Brain Tissue Indicates Disturbances in Subjects with Alzheimer's Disease and Dementia with Lewy Bodies

    Graham, S. F., Nasarauddin, M. B., Carey, M., McGuinness, B., Holscher, C., Kehoe, P. G., Love, S., Passmore, A. P., Elliott, C. T., Meharg, A. & Green, B. D., 2015, In: JAD: Journal of Alzheimer's Disease. 44, 3, p. 851-857 8 p.

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)
  • Reciting the months of the year backwards: what is a 'normal' score?

    Cunningham, E., Passmore, A., McAuley, D. & McGuinness, B., May 2015, In: Age and Ageing. 44, 3, p. 537-538 2 p.

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)
  • Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease

    Graham, S. F., Chevallier, O. P., Elliott, C. T., Hölscher, C., Johnston, J., McGuinness, B., Kehoe, P. G., Passmore, A. P. & Green, B. D., 24 Mar 2015, In: PloS one. 10, 3, 16 p., e0119452.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    145 Citations (Scopus)
    406 Downloads (Pure)
  • 2014

    Age-Associated Changes of Brain Copper, Iron, and Zinc in Alzheimer's Disease and Dementia with Lewy Bodies

    Graham, S. F., Nasaruddin, M. B., Carey, M., Holscher, C., McGuinness, B., Kehoe, P. G., Love, S., Passmore, P., Elliott, C. T., Meharg, A. A. & Green, B. D., 13 Oct 2014, In: JAD: Journal of Alzheimer's Disease. 42, 4, p. 1407-1413

    Research output: Contribution to journalArticlepeer-review

    54 Citations (Scopus)
  • Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A. & Sims, R. & 6 others, Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S. & Powell, J. F., Dec 2014, In: Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p.

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)
  • Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Harold, D., Sims, R., Gerrish, A., Chapman, J., Escott-Price, V., Abraham, R. & Hollingworth, P. & 74 others, Hamshere, M., Singh Pahwa, J., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Williams, K., Lovestone, S., Powell, J. F., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P., Craig, D., Mcguinness, B., Johnston, J. A., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Guerreiro, R., Singleton, A. B., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Nöthen, M. M., Holmans, P. A., O'Donovan, M. C., Owen, M. J., Williams, J., Stewart, R. C. & Sham, P., 16 Sept 2014, In: PLoS Medicine. 11, 9

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    66 Citations (Scopus)
    252 Downloads (Pure)
  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

    Escott-Price, V., Bellenguez, C., Wang, L. S., Choi, S. H., Harold, D., Jones, L., Holmans, P., Gerrish, A., Vedernikov, A., Richards, A., DeStefano, A. L., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Jun, G., Bis, J. C., Beecham, G. W., Grenier-Boley, B. & Russo, G. & 167 others, Thornton-Wells, T. A., Denning, N., Smith, A. V., Chouraki, V., Thomas, C., Arfan Ikram, M., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Schmidt, H., Kunkle, B., Dunstan, M. L., Vronskaya, M., Johnson, A. D., Ruiz, A., Bihoreau, M. T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Becker, C. B. T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Hernández, I., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiévet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Scarpini, E., Bonuccelli, U., Mancuso, M., Siciliano, G., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Frank-García, A., Panza, F., Solfrizzi, V., Caffarra, P., Nacmias, B., Perry, W., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Psaty, B. M., Haines, J. L., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Van Broeckhoven, C., Farrer, L. A., Van Duijn, C. M., Ramirez, A., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., 12 Jun 2014, In: PLoS ONE. 9, 6, e94661.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    97 Citations (Scopus)
  • Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.

    Cruchaga, C., Karch, C., Jin, S., Benitez, B., Cai, Y., Guerrera, R., Harari, O., Norton, J., Budde, J., Bertelsen, S., Jeng, A., Cooper, B., Skorupa, T., Carrell, D., Levitz, D., Hsu, S., Choi, J., Ryten, M., Hardy, J. & Trabzuni, D. & 61 others, Weale, M., Ramasami, A., Smith, C., Sassy, C., Bras, J., Gibbs, J., Hernandez, D., Lupton, M., Powell, J., Forabosco, P., Ridge, P., Corcoran, C., Tschanz , J., Norton, M., Munger, R., Schmutz , C., Leary, M., Demirci , F., Bamne, M., Wang, X., Lopez, O., Ganguli, M., Medway, C., Turton, J., Lord, J., Braae, A., Barber, I., Brown, K., Passmore, A., Craig, D., Todd, S., Johnston, J., McGuinness, B., Heun, R., Kolsch, H., Kehoe, P., Hooper, N., Wilcock, G., Vardy, E., Mann, D., Pickering-Brown, S., Kalsheker, N., Lowe, J., Morgan, K., Smith, D., Warden, D., Holmes, C., Pastor, P., Lorenzo-Betancor , O., Brkanac , Z., Scott, E., Topol, E., Rogaeva, E., Singleton, A., Hardy, J., Kamboh, M., St George-Hyslop , P., Cairns, N., Morris, J., Kauwe, J. & Goate, A., 23 Jan 2014, In: Nature. 505, p. 550-554 5 p.

    Research output: Contribution to journalArticlepeer-review

    384 Citations (Scopus)
  • 2013
    Open Access
    11 Citations (Scopus)
  • Plasma Clusterin Levels and the rs11136000 Genotype in Individuals with Mild Cognitive Impairment and Alzheimer's Disease

    Mullan, G. M., McEneny, J., Fuchs, M., McMaster, C., Todd, S., McGuinness, B., Henry, M., Passmore, A. P., Young, I. S. & Johnston, J. A., Nov 2013, In: Current Alzheimer Research. 10, 9, p. 973-978 6 p.

    Research output: Contribution to journalArticlepeer-review

    27 Citations (Scopus)
  • 2012

    Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

    Proitsi, P., Lupton, M. K., Dudbridge, F., Tsolaki, M., Hamilton, G., Daniilidou, M., Pritchard, M., Lord, K., Martin, B. M., Craig, D., Todd, S., McGuinness, B., Hollingworth, P., Harold, D., Kloszewska, I., Soininen, H., Mecocci, P., Velas, B., Gill, M. & Lawlor, B. & 6 others, Rubinsztein, D. C., Brayne, C., Passmore, P. A., Williams, J., Lovestone, S. & Powell, J. F., Aug 2012, In: Neurobiology of Aging. 33, 8, p. 1843.e9-17

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)
  • Cochrane review on 'Statins for the treatment of dementia'

    McGuinness, B., O'Hare, J., Craig, D., Bullock, R., Malouf, R. & Passmore, P., 2012, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

    57 Citations (Scopus)
  • Genetic variation in MME in relation to neprilysin protein and enzyme activity, Aβ levels, and Alzheimer's disease risk

    Miners, S., van Helmond, Z., Barker, R., Passmore, P. A., Johnston, J. A., Todd, S., McGuinness, B. M., Panza, F., Seripa, D., Solfrizzi, V., Love, S., Prince, J. A. & Kehoe, P. G., 2012, In: International journal of molecular epidemiology and genetics. 3, 1, p. 30-8 9 p.

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)
  • The development of effective biomarkers for Alzheimer's disease: a review

    Henry, M. S., Passmore, A. P., Todd, S., McGuinness, B., Craig, D. & Johnston, J. A., 2012, In: International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticlepeer-review

    50 Citations (Scopus)
  • The Role of Variation at AβPP, PSEN1, PSEN2, and MAPT in Late Onset Alzheimer's Disease

    Gerrish, A., Russo, G., Richards, A., Moskvina, V., Ivanov, D., Harold, D., Sims, R., Abraham, R., Hollingworth, P., Chapman, J., Hamshere, M., Pahwa, J. S., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S. & Powell, J. & 73 others, Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Johnston, J. A., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Kölsch, H., Heun, R., Schürmann, B., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Davies, G., Harris, S. E., Starr, J. M., Deary, I. J., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K.-H., Klopp, N., Wichmann, H.-E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Jones, L., Holmans, P. A., O'Donovan, M. C., Owen, M. J., Williams, J. & Morgan, K., 2012, In: JAD: Journal of Alzheimer's Disease. 28, 2, p. 377-87 11 p.

    Research output: Contribution to journalArticlepeer-review

    58 Citations (Scopus)
    33 Downloads (Pure)
  • 2011

    A multi-center study of ACE and the risk of late-onset Alzheimer's disease

    Belbin, O., Brown, K., Shi, H., Medway, C., Abraham, R., Passmore, P., Mann, D., Smith, A. D., Holmes, C., McGuinness, B., Craig, D., Warden, D., Heun, R., Kölsch, H., Love, S., Kalsheker, N., Williams, J., Owen, M. J., Carrasquillo, M. & Younkin, S. & 2 others, Kehoe, P. G. & Morgan, K., 2011, In: JAD: Journal of Alzheimer's Disease. 24, 3, p. 587-97 11 p.

    Research output: Contribution to journalArticlepeer-review

    38 Citations (Scopus)
  • A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD)

    Proitsi, P., Hamilton, G., Tsolaki, M., Lupton, M., Daniilidou, M., Hollingworth, P., Archer, N., Foy, C., Stylios, F., McGuinness, B., Todd, S., Lawlor, B., Gill, M., Brayne, C., Rubinsztein, D. C., Owen, M., Williams, J., Craig, D., Passmore, P. & Lovestone, S. & 1 others, Powell, J. F., Mar 2011, In: Neurobiology of Aging. 32, 3, p. 434-442 9 p.

    Research output: Contribution to journalArticlepeer-review

    64 Citations (Scopus)
  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

    Hollingworth, P., Harold, D., Sims, R., Gerrish, A., Lambert, J. C., Carrasquillo, M. M., Abraham, R., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Jones, N., Stretton, A., Thomas, C., Richards, A., Ivanov, D., Widdowson, C., Chapman, J., Lovestone, S. & Powell, J. & 152 others, Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Beaumont, H., Warden, D., Wilcock, G., Love, S., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Hardy, J., Mead, S., Fox, N. C., Rossor, M., Collinge, J., Maier, W., Jessen, F., Ruther, E., Schurmann, B., Heun, R., Kolsch, H., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frolich, L., Hampel, H., Gallacher, J., Hull, M., Rujescu, D., Giegling, I., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Muhleisen, T. W., Nothen, M. M., Moebus, S., Jockel, K. H., Klopp, N., Wichmann, H. E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Van Duijn, C. M., Breteler, M. M. B., Ikram, M. A., DeStefano, A. L., Fitzpatrick, A. L., Lopez, O., Launer, L. J., Seshadri, S., Berr, C., Campion, D., Epelbaum, J., Dartigues, J. F., Tzourio, C., Alperovitch, A., Lathrop, M., Feulner, T. M., Friedrich, P., Riehle, C., Krawczak, M., Schreiber, S., Mayhaus, M., Nicolhaus, S., Wagenpfeil, S., Steinberg, S., Stefansson, H., Stefansson, K., Snaedal, J., Bjornsson, S., Jonsson, P. V., Chouraki, V., Genier-Boley, B., Hiltunen, M., Soininen, H., Combarros, O., Zelenika, D., Delepine, M., Bullido, M. J., Pasquier, F., Mateo, I., Frank-Garcia, A., Porcellini, E., Hanon, O., Coto, E., Alvarez, V., Bosco, P., Siciliano, G., Mancuso, M., Panza, F., Solfrizzi, V., Nacmias, B., Sorbi, S., Bossu, P., Piccardi, P., Arosio, B., Annoni, G., Seripa, D., Pilotto, A., Scarpini, E., Galimberti, D., Brice, A., Hannequin, D., Licastro, F., Jones, L., Holmans, P. A., Jonsson, T., Riemenschneider, M., Morgan, K., Younkin, S. G., Owen, M. J., O'Donovan, M., Amouyel, P. & Williams, J., 01 May 2011, In: Nature Genetics. 43, 5, p. 429-35

    Research output: Contribution to journalArticlepeer-review

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    1632 Citations (Scopus)
    256 Downloads (Pure)
  • Genome-wide association study of Alzheimer's disease with psychotic symptoms

    Hollingworth, P., Sweet, R., Sims, R., Harold, D., Russo, G., Abraham, R., Stretton, A., Jones, N., Gerrish, A., Chapman, J., Ivanov, D., Moskvina, V., Lovestone, S., Priotsi, P., Lupton, M., Brayne, C., Gill, M., Lawlor, B., Lynch, A. & Craig, D. & 22 others, McGuinness, B., Johnston, J., Holmes, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Holmans, P., Jones, L., Devlin, B., Klei, L., Barmada, M. M., Demirci, F. Y., Dekosky, S. T., Lopez, O. L., Passmore, P., Owen, M. J., O'Donovan, M. C., Mayeux, R., Kamboh, M. I., Williams, J. & the GERAD Consortium, 18 Oct 2011, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

    106 Citations (Scopus)
  • 2010

    Apolipoprotein ɛ4 and neuropsychological performance in Alzheimer's disease and vascular dementia

    McGuinness, B., Carson, R., Barrett, S. L., Craig, D. & Passmore, A. P., 08 Oct 2010, In: Neuroscience Letters. 483, 1, p. 62-66 5 p.

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)
    223 Downloads (Pure)
  • Attention deficits in Alzheimer's disease and vascular dementia

    McGuinness, B., Barrett, S., Craig, D., Lawson, J. & Passmore, P., Feb 2010, In: Journal of neurology, neurosurgery, and psychiatry. 81, 2, p. 157-159 3 p.

    Research output: Contribution to journalArticlepeer-review

    64 Citations (Scopus)
  • Can statins prevent or help treat Alzheimer's disease?

    McGuinness, B. & Passmore, P., 26 May 2010, In: Journal of Alzheimer's Disease. 20, 3, p. 925-933 9 p.

    Research output: Contribution to journalArticlepeer-review

    59 Citations (Scopus)
    899 Downloads (Pure)
  • Designing appropriate clincial trials to assess ACEI use and cognitive decline in older adults with hypertension

    Todd, S., McGuinness, B. & Passmore, P., 11 Jan 2010, In: Arch Intern Med.

    Research output: Contribution to journalArticlepeer-review

    File
    13 Downloads (Pure)
  • Designing appropriate clinical trials to assess ACEI use and cognitive decline in older adults with hypertension

    Todd, S., McGuinness, B. & Passmore, A. P., 11 Jan 2010, In: Archives of Internal Medicine. 170, 1, p. 107

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)
  • Executive functioning in Alzheimer's disease and vascular dementia

    McGuinness, B., Barrett, S. L., Craig, D., Lawson, J. & Passmore, A. P., 01 Jun 2010, In: International Journal of Geriatric Psychiatry. 25, 6, p. 562-568 7 p.

    Research output: Contribution to journalArticlepeer-review

    62 Citations (Scopus)
    333 Downloads (Pure)
  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

    Jones, L., Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Pahwa, J. S., Jones, N., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K. & Brayne, C. & 62 others, Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schurmann, B., Van Den Bussche, H., Heuser, I., Peters, O., Kornhuber, J., Wiltfang, J., Dichgans, M., Frolich, L., Hampel, H., Hull, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Muhleisen, T. W., Nothen, M. M., Moebus, S., Jockel, K. H., Klopp, N., Wichmann, H. E., Ruther, E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Hardy, J., O'Donovan, M. C., Owen, M. J. & Williams, J., 15 Nov 2010, In: PLoS ONE. 5, 11, e13950.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    333 Citations (Scopus)
    124 Downloads (Pure)
  • Inflammation and anti-inflammatory strategies for Alzheimer disease: a mini review

    McNaull, B. B. A., Todd, S., McGuinness, B. & Passmore, A. P., 02 Jan 2010, In: Gerontology. 56, 1, p. 3-14 12 p.

    Research output: Contribution to journalArticlepeer-review

    101 Citations (Scopus)
    149 Downloads (Pure)
  • Northern Ireland dementia strategy

    Todd, S., Wilson, D., McGuinness, B., Craig, D. & Passmore, A. P., 23 Aug 2010, In: International Journal of Geriatric Psychiatry. 25, 9, p. 902-904 3 p.

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)
    275 Downloads (Pure)
  • Statins for the treatment of dementia

    McGuinness, B., O'Hare, J., Craig, D., Bullock, R., Malouf, R. & Passmore, P., 04 Aug 2010, In: Cochrane Database of Systematic Reviews. 8, 51 p., CD007514.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    134 Citations (Scopus)
    1438 Downloads (Pure)
  • 2009

    A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets.

    Liu, W., Todd, S., Coulson, D., Irvine, B., Passmore, P., McGuinness, B., McConville, M., Craig, D. & Johnston, J., Jan 2009, In: Journal of Neurochemistry. 108, 2, p. 341-349 9 p.

    Research output: Contribution to journalArticlepeer-review

    34 Citations (Scopus)
  • Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

    McGuinness, B., Todd, S., Passmore, P. & Bullock, R., 2009, In: Cochrane Database of Systematic Reviews. null, 4, CD004034.

    Research output: Contribution to journalArticlepeer-review

    293 Citations (Scopus)