Projects per year
Personal profile
Research Interests
Research Focus
Research in my group aims to understand the mechanistic basis of antimicrobial tolerance exhibited by microbial biofilms, and to develop effective biofilm detection methodologies (wound biofilm sensors) and eradication therapies for the treatment of chronic biofilm-mediated infections. Research in the group is highly multidisciplinary in nature; from medicinal chemistry, chemical biology, to molecular microbiology, functional metagenomics and bioinformatics. Among our interests are the identification of important regulators of biofilm formation (including proteases, such as lasB in P. aeruginosa) and bacterial virulence, and development of novel approaches for biofilm control, including atmospheric pressure, non-thermal plasmas (or ‘cold’ plasmas). We have an active research interest in antibiotic biodiscovery from extremophilic bacteria and archaea, having developed a unique and exciting programme of halophile research, based on extreme halophiles from 250M year old halite evaporites and spleothems from Kilroot Saltmine, N. Ireland using both culture-based and culture-independent approaches. Our research is multidisciplinary in nature, enjoying active national and international collaborations with academic and industry partners. In collaboration with the Centre for Plasma Physics and the Institute for Global Food Security (IGFS), we are elucidating the mechanisms of action of Atmospheric Pressure, Non Thermal Plasma (APNTP) in biofilm control, aiming to developing clinical and AgriFood applications of this exciting technology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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R4133GFS: Pathogen Surveillance in Agriculture, Food and the Environment (PATH-SAFE) Summary
McGrath, J., Bamford, C., Cameron, S., Creevey, C., Gilmore, B., Gilpin, D., Hughes, C., Kelly, S., McKinley, J. & Tunney, M.
23/11/2022 → …
Project: Research
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R3253GFS: IN Silico Informed metaGenomic Harvesting Technology platform (INSIGHT)
Allen, C. C. R., Gilmore, B., Huang, M. & Law, C.
06/01/2021 → …
Project: Research
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R1102CCE: 3D Printed Colourimetric Indicator Strip (3DCIS) for Non-Invasive, On-demand Chronic Wound Monitoring
Mills, A., Gilmore, B. & Stewart, D.
28/08/2019 → …
Project: Research
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Cold atmospheric pressure plasma-antibiotic synergy in Pseudomonas aeruginosa biofilms is mediated via oxidative stress response
Maybin, J. A., Thompson, T. P., Flynn, P. B., Skvortsov, T., Hickok, N. J., Freeman, T. A. & Gilmore, B. F., Dec 2023, In: Biofilm. 5, 100122.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Exploring halophilic environments as a source of new antibiotics
Thompson, T. P. & Gilmore, B. F., 20 Apr 2023, (Early online date) In: Critical Reviews in Microbiology. 30 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Mesenteric microbiology and inflammatory bowel disease: improved understanding due to accelerating innovation and sophistication of molecular technology
Kiernan, M. G., Dunne, S. S., McDermott, K., Jakeman, P., Gilmore, B., Thompson, T. P., Kelly, S., Coffey, J. C. & Dunne, C. P., 05 Jan 2023, The mesentery and inflammation. Coffey, J. C. (ed.). Springer, Cham, p. 111-126 (Progress in Inflammation Research; vol. 90).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Draft Genome Sequences of Halobacterium sp. Strains KA-4 and KA-6, Two Extremely Halophilic Archaea Isolated from a Triassic Salt Deposit in Northern Ireland
McMahon, F., Lonergan, C. M., Gilmore, B. F. & Megaw, J., 20 Jan 2022, In: Microbiology resource announcements. 11, 1, e01165-21.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Extracts of Sida cordifolia contain polysaccharides possessing immunomodulatory activity and rosmarinic acid compounds with antibacterial activity
Iqbal, H., Wright, C. L., Jones, S., da Silva, G. R., McKillen, J., Gilmore, B. F., Kavanagh, O. & Green, B. D., 27 Jan 2022, In: BMC complementary medicine and therapies. 22, 27.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Downloads (Pure)
Datasets
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Dataset for "Non-invasive, 3D printed, colourimetric, early wound-infection indicator"
Mills, A. (Creator), Yusufu, D. (Creator), Gilmore, B. (Creator) & Magee, E. (Creator), Queen's University Belfast, 01 Dec 2021
DOI: 10.17034/3ff47a99-e6c0-4ecd-9749-46cc91e53bdf
Dataset
File
Prizes
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A Denver Russell Memorial Teleclass Lecture 2014 ‘Atmospheric pressure, non-thermal plasmas for biofilm and infection control’
Gilmore, Brendan (Recipient), 08 Apr 2014
Prize: Prize (including medals and awards)
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Annual Joint Norbrook Royal Society of Biology Lecture 2019
Gilmore, Brendan (Recipient), 20 Mar 2019
Prize: Prize (including medals and awards)
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Fellow of the Linnean Society
Gilmore, Brendan (Recipient), 15 Mar 2018
Prize: Fellowship awarded competitively
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Fellow of the Royal Society of Biology
Gilmore, Brendan (Recipient), 01 Apr 2020
Prize: Fellowship awarded competitively
Activities
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Science vs. Microbes
Johanne Barry (Invited speaker), Sara Cordeiro (Chair), Emma McAlister (Organiser), Ryan Donnelly (Invited speaker), Brendan Gilmore (Invited speaker) & Aaron Brady (Invited speaker)
20 Feb 2020Activity: Talk or presentation types › Public lecture/debate/seminar
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Non Thermal Plasma Exposure Enhances Antibiotic Sensitivity and Immune Response to Pathogenic Biofilms
Brendan Gilmore (Advisor)
10 Dec 2019 → 11 Dec 2019Activity: Talk or presentation types › Invited talk
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Application of Cold Plasmas in the AgriFood Industry
Brendan Gilmore (Advisor)
05 Dec 2019Activity: Talk or presentation types › Invited talk
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External Examiner MPhil
Brendan Gilmore (Examiner)
26 Nov 2019Activity: Examination types › PhD external examination
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Cold Plasmas: a potential approach to mitigate microbiological and toxicological risks in the food & feed chain
Brendan Gilmore (Advisor)
15 Oct 2019Activity: Talk or presentation types › Invited talk