Photo of Brian Walker

Brian Walker



Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile


Professor Walker was appointed in September 1998 to the Allen J. McClay Chair in Biomedicinal Chemistry to establish a Biomolecular Sciences programme within the School. His research interests are focused on the development and application of novel inhibitors for the identification and validation of protease targets of biomedical and pharmaceutical importance. This research is characterized by a fusion of biological chemistry and cell and molecular biology.

Fingerprint Dive into the research topics where Brian Walker is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.


Research Output

A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea

Zhang, L., Chen, X., Wu, Y., Zhou, M., Ma, C., Xi, X., Chen, T., Walker, B., Shaw, C. & Wang, L., 11 Apr 2018, In : Scientific Reports. 8, 9 p., 5851.

Research output: Contribution to journalArticle

Open Access
  • 2 Citations (Scopus)
    170 Downloads (Pure)

    A Structural and Functional Analogue of a Bowman Birk-type Protease Inhibitor from Odorrana Schmackeri

    Wu, Y., Long, Q., Xu, Y., Guo, S., Chen, T., Wang, L., Zhou, M., Zhang, Y., Shaw, C. & Walker, B., Apr 2017, In : Bioscience Reports. 37, 2

    Research output: Contribution to journalArticle

    Open Access
  • 8 Citations (Scopus)
    196 Downloads (Pure)

    Detection and inhibition of ENaC-activating proteases associated with airway dehydration in COPD

    Martin, L., Reihill, J., Douglas, L., Ferguson, T. & Walker, B., Sep 2017, In : European Respiratory Journal. 50, Suppl 61, PA4933.

    Research output: Contribution to journalMeeting abstract

  • Neutrophil Elastase Activity is Associated with Exacerbations and Lung Function Decline in Bronchiectasis

    Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393

    Research output: Contribution to journalArticle

    Open Access
  • 74 Citations (Scopus)
    361 Downloads (Pure)

    A Selective Irreversible Inhibitor of Furin Does Not Prevent Pseudomonas Aeruginosa Exotoxin A-Induced Airway Epithelial Cytotoxicity

    Ferguson, T. E. G., Reihill, J. A., Walker, B., Hamilton, R. A. & Martin, S. L., 26 Jul 2016, In : PLoS ONE. 11, 7, 9 p., e0159868.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Citations (Scopus)
    188 Downloads (Pure)