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Cathy Fenning


  • Room 02.015 - Clinical Science A

    United Kingdom

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  • 36 Similar Profiles
Colorectal Neoplasms Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
irinotecan Medicine & Life Sciences
Drug Resistance Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
Caspase 8 Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

Research Output 2008 2016

  • 8 Article
  • 3 Conference contribution
  • 1 Meeting abstract
8 Citations (Scopus)
169 Downloads (Pure)

FLIP: a targetable mediator of resistance to radiation in non-small cell lung cancer

McLaughlin, K. A., Nemeth, Z., Bradley, C. A., Humphreys, L., Stasik, I., Fenning, C., Majkut, J., Higgins, C., Crawford, N., Holohan, C., Johnston, P. G., Harrison, T., Hanna, G. G., Butterworth, K. T., Prise, K. M. & Longley, D. B., 01 Oct 2016, In : Molecular Cancer Therapeutics. p. 2432-2441 11 p.

Research output: Contribution to journalArticle

Open Access
Ionizing Radiation
Non-Small Cell Lung Carcinoma
Caspase 8
Cell Death
27 Citations (Scopus)

HDAC Inhibition Overcomes Acute Resistance to MEK Inhibition in BRAF-Mutant Colorectal Cancer by Downregulation of c-FLIPL

Carson, R., Celtikci, B., Fenning, C., Javadi, A., Crawford, N., Perez Carbonell, L., Lawler, M., Longley, D. B., Johnston, P. G. & Van Schaeybroeck, S., 15 Jul 2015, In : Clinical Cancer Research. 21, 14, p. 3230-3240 11 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Histone Deacetylase Inhibitors
Small Interfering RNA
47 Citations (Scopus)
289 Downloads (Pure)

ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer

Van Schaeybroeck, S., Kalimutho, M., Dunne, P. D., Carson, R., Allen, W., Jithesh, P. V., Redmond, K. L., Sasazuki, T., Shirasawa, S., Blayney, J., Michieli, P., Fenning, C., Lenz, H-J., Lawler, M., Longley, D. B. & Johnston, P. G., 26 Jun 2014, In : Cell Reports. 7, 6, p. 1940-1955 16 p.

Research output: Contribution to journalArticle

Open Access
Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Chemical activation
Systems Biology
19 Citations (Scopus)
271 Downloads (Pure)

Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine

Schmid, D., Fay, F., Small, D. M., Jaworski, J., Riley, J. S., Tegazzini, D., Fenning, C., Jones, D. S., Johnston, P. G., Longley, D. B. & Scott, C. J., Dec 2014, In : Molecular therapy : the journal of the American Society of Gene Therapy. 22, 12, p. 2083-2092 10 p.

Research output: Contribution to journalArticle

Open Access
TNF-Related Apoptosis-Inducing Ligand Receptors
Colorectal Neoplasms
Pharmaceutical Preparations

The prognostic and therapeutic value of EpHA2 in early colorectal cancer (CRC).

Dasgupta, S., Van Schaeybroeck, S., Dunne, P., McArt, D., Fenning, C., Ong, C. W., Arthur, K., Salto-Tellez, M., Wilson, R. & Johnston, P., 2014, In : Journal of Clinical Oncology. 32, (suppl; abstr 3581)

Research output: Contribution to journalMeeting abstract

Colorectal Neoplasms
Multivariate Analysis
Eph Family Receptors
Blood Vessels