Cathy Fenning

Mrs

Senior Technician, School of Medicine, Dentistry and Biomedical Sciences
Wellcome Wolfson Institute for Experimental Medicine

Phone+44 (0)28 9097 2690
Emailc.fenning@qub.ac.uk

Room 03.003 - Medical Biology Centre
United Kingdom

Research output per year

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8 Article
3 Conference contribution
1 Meeting abstract

8 results

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2016
FLIP: a targetable mediator of resistance to radiation in non-small cell lung cancer
McLaughlin, K. A., Nemeth, Z., Bradley, C. A., Humphreys, L., Stasik, I., Fenning, C., Majkut, J., Higgins, C., Crawford, N., Holohan, C., Johnston, P. G., Harrison, T., Hanna, G. G., Butterworth, K. T., Prise, K. M. & Longley, D. B., 01 Oct 2016, In: Molecular Cancer Therapeutics. p. 2432-2441 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
12 Citations (Scopus)

234 Downloads (Pure)
2015
HDAC Inhibition Overcomes Acute Resistance to MEK Inhibition in BRAF-Mutant Colorectal Cancer by Downregulation of c-FLIPL
Carson, R., Celtikci, B., Fenning, C., Javadi, A., Crawford, N., Perez Carbonell, L., Lawler, M., Longley, D. B., Johnston, P. G. & Van Schaeybroeck, S., 15 Jul 2015, In: Clinical Cancer Research. 21, 14, p. 3230-3240 11 p.
Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus)
2014
ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer
Van Schaeybroeck, S., Kalimutho, M., Dunne, P. D., Carson, R., Allen, W., Jithesh, P. V., Redmond, K. L., Sasazuki, T., Shirasawa, S., Blayney, J., Michieli, P., Fenning, C., Lenz, H-J., Lawler, M., Longley, D. B. & Johnston, P. G., 26 Jun 2014, In: Cell Reports. 7, 6, p. 1940-1955 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
61 Citations (Scopus)

367 Downloads (Pure)
Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine
Schmid, D., Fay, F., Small, D. M., Jaworski, J., Riley, J. S., Tegazzini, D., Fenning, C., Jones, D. S., Johnston, P. G., Longley, D. B. & Scott, C. J., Dec 2014, In: Molecular therapy : the journal of the American Society of Gene Therapy. 22, 12, p. 2083-2092 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
23 Citations (Scopus)

353 Downloads (Pure)
2012
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis
Kerr, E., Holohan, C., McLaughlin, KM., Majkut, J., Dolan, S., Redmond, K., Riley, J., McLaughlin, K., Stasik, I., Crudden, M., Van Schaeybroeck, S., Fenning, C., O'Connor, R., Kiely, P., Sgobba, M., Haigh, D., Johnston, PG. & Longley, DB., Aug 2012, In: Cell Death and Differentiation. 19, 8, p. 1317-1327 11 p., e1745.
Research output: Contribution to journal › Article › peer-review
64 Citations (Scopus)
2011
Oncogenic Kras Promotes Chemotherapy-Induced Growth Factor Shedding via ADAM17.
Van Schaeybroeck, S., Kyula, J., Fenton, A., Fenning, C., Sasazuki, T., Shirasawa, S., Longley, D. & Johnston, P., 01 Jan 2011, In: Cancer Research. 25, 3, p. 1071-1080 10 p.
Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus)
2010
Chemotherapy-Induced Activation of ADAM-17: A Novel Mechanism of Drug Resistance in Colorectal Cancer
Kyula, J., Van Schaeybroeck, S., Doherty, J., Fenning, C., Longley, D. & Johnston, P., 01 Jul 2010, In: Clinical Cancer Research. 16, 13, p. 3378-3389 12 p.
Research output: Contribution to journal › Article › peer-review
69 Citations (Scopus)
2008
Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line Models
Allen, W., Coyle, V., Jithesh, P., Proutski, I., Stevenson, L., Fenning, C., Longley, D., Wilson, R., Gordon, M., Lenz, H. J. & Johnston, P., 15 Oct 2008, In: Clinical Cancer Research. 14, 20, p. 6647-6655 9 p.
Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus)

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