Cecilia O'Kane

2024

Cell-based therapies for ARDS - Where are we now?

Curley, G. F., O'Kane, C. M., McAuley, D. F., Matthay, M. A. & Laffey, J. G., 07 Feb 2024, (Early online date) In: American Journal of Respiratory and Critical Care Medicine. 9 p.

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5 Citations (Scopus)

81 Downloads (Pure)

Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis

Kenny, G., Saini, G., Gaillard, C. M., Negi, R., Alalwan, D., Garcia Leon, A., McCann, K., Tinago, W., Kelly, C., Cotter, A. G., de Barra, E., Horgan, M., Yousif, O., Gautier, V., Landay, A., McAuley, D., Feeney, E. R., O'Kane, C. & Mallon, P. W., 15 Aug 2024, In: Heliyon. 10, 15, e34694.

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Human mesenchymal stromal cells inhibit Mycobacterium avium replication in clinically relevant models of lung infection

Shaw, T. D., Krasnodembskaya, A. D., Schroeder, G. N., Doherty, D. F., Silva, J. D., Tandel, S. M., Su, Y., Butler, D., Ingram, R. J. & O’Kane, C. M., Aug 2024, In: Thorax. 79, 8, p. 778-787

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1 Citation (Scopus)

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Mechanical stretch induces senescence of lung epithelial cells and drives fibroblast activation by paracrine mechanisms

Martín-Vicente, P., López-Martínez, C., López-Alonso, I., Exojo-Ramírez, S. M., Duarte-Herrera, I. D., Amado-Rodríguez, L., Ordoñez, I., Cuesta-Llavona, E., Gómez, J., Campo, N., O'Kane, C. M., McAuley, D. F., Huidobro, C. & Albaiceta, G. M., 12 Aug 2024, (Early online date) In: American Journal of Respiratory Cell and Molecular Biology.

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Mesenchymal stromal cells reduce inflammation and improve lung function in a mouse model of cystic fibrosis lung disease

Doherty, D. F., Roets, L. E., Dougan, C. M., Brown, R. R., Hawthorne, I. J., O'Kane, C., Krasnodembskaya, A. D., Mall, M. A., Taggart, C. C. & Weldon, S., 28 Dec 2024, In: Scientific Reports. 14, 30899.

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Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes

Antcliffe, D. B., Mi, Y., Santhakumaran, S., Burnham, K. L., Prevost, A. T., Ward, J. K., Marshall, T. J., Bradley, C., Al-Beidh, F., Hutton, P., McKechnie, S., Davenport, E. E., Hinds, C. J., O'Kane, C. M., McAuley, D. F., Shankar-Hari, M., Gordon, A. C. & Knight, J. C., 20 May 2024, In: Thorax. 79, 6, p. 515-523

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3 Citations (Scopus)

8 Downloads (Pure)

The effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal compared with conventional lung protective ventilation on cardiac function

McGuigan, P. J., Bowcock, E. M., Barrett, N. A., Blackwood, B., Boyle, A. J., Cadamy, A. J., Camporota, L., Conlon, J., Cove, M. E., Gillies, M. A., McDowell, C., McNamee, J. J., O'Kane, C. M., Puxty, A., Sim, M., Parsons-Simmonds, R., Szakmany, T., Young, N., Orde, S. & McAuley, D. F., 01 Jan 2024, In: Critical Care Explorations. 6, 1, 13 p., e1028.

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1 Citation (Scopus)

30 Downloads (Pure)

TRPV2 modulates mechanically induced ATP release from human bronchial epithelial cells

Dunne, O. M., Martin, S. L., Sergeant, G. P., McAuley, D. F., O’Kane, C. M., Button, B., McGarvey, L. P. & Lundy, F. T., 27 Apr 2024, In: Respiratory Research. 25, 10 p., 188.

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2023

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Pienkos, S. M., Moore, A. R., Guan, J., Levitt, J. E., Matthay, M. A., Baron, R. M., Conlon, J., McAuley, D. F., O’Kane, C. M. & Rogers, A. J., 28 Mar 2023, (Early online date) In: Critical Care. 27, 1, 126.

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12 Citations (Scopus)

35 Downloads (Pure)

Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS)

Mehta, P., Samanta, R. J., Wick, K., Coll, R. C., Mawhinney, T., McAleavey, P. G., Boyle, A. J., Conlon, J., Shankar-Hari, M., Rogers, A., Calfee, C. S., Matthay, M. A., Summers, C., Chambers, R. C., McAuley, D. F. & O'Kane, C. M., 26 Dec 2023, (Early online date) In: Thorax. 9 p.

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4 Citations (Scopus)

278 Downloads (Pure)

Elevated plasma Interleukin-18 identifies high-risk acute respiratory distress syndrome patients not distinguished by prior latent class analyses using traditional inflammatory cytokines: a retrospective analysis of two randomized clinical trials

Moore, A. R., Pienkos, S. M., Sinha, P., Guan, J., O'Kane, C. M., Levitt, J. E., Wilson, J. G., Shankar-Hari, M., Matthay, M. A., Calfee, C. S., Baron, R. M., McAuley, D. F. & Rogers, A. J., 01 Dec 2023, In: Critical care medicine. 51, 12, p. e269-e274 6 p.

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6 Citations (Scopus)

Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis

Su, Y., Silva, J. D., Doherty, D., Simpson, D. A., Weiss, D. J., Rolandsson-Enes, S., McAuley, D. F., O'Kane, C. M., Brazil, D. P. & Krasnodembskaya, A. D., 24 Oct 2023, In: Thorax. 78, 6, p. 617-630 14 p.

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22 Citations (Scopus)

48 Downloads (Pure)

Mesenchymal Stromal Cells in ARDS: more Questions than Answers

Millar, J. E. & O'Kane, C. M., 08 Nov 2023, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.

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1 Citation (Scopus)

Repair of acute respiratory distress syndrome in COVID-19 by stromal cells (REALIST-COVID Trial): A multicentre, randomised, controlled trial

Gorman, E. A., Rynne, J., Gardiner, H. J., Rostron, A. J., Bannard-Smith, J., Bentley, A. M., Brealey, D., Campbell, C., Curley, G., Clarke, M., Dushianthan, A., Hopkins, P., Jackson, C., Kefela, K., Krasnodembskaya, A., Laffey, J. G., McDowell, C., McFarland, M., McFerran, J. & McGuigan, P. & 12 others, Perkins, G. D., Silversides, J., Smythe, J., Thompson, J., Tunnicliffe, W. S., Welters, I. D., Amado-Rodríguez, L., Albaiceta, G., Williams, B., Shankar-Hari, M., McAuley, D. F. & O'Kane, C. M., 01 Aug 2023, In: American Journal of Respiratory and Critical Care Medicine. 208, 3, p. 256-269

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11 Citations (Scopus)

53 Downloads (Pure)

Simvastatin in critically ill patients with Covid-19

Hills, T. E., Lorenzi, E., Berry, L. R., Shyamsundar, M., Al-Beidh, F., Annane, D., Arabi, Y., Aryal, D., Au, C., Beane, A., Bhimani, Z., Bonten, M., Bradbury, C. A., Brunkhorst, F. M., Burrell, A., Buxton, M., Calfee, C. S., Cecconi, M., Cheng, A. C. & Cove, M. E. & 31 others, Detry, M. A., Estcourt, L. J., Fitzgerald, M., Goligher, E. C., Goossens, H., Green, C., Haniffa, R., Harrison, D. A., Hashmi, M., Higgins, A. M., Huang, D. T., Ichihara, N., Jayakumar, D., Kruger, P. S., Lamontagne, F., Lampro, L., Lawler, P. R., Marshall, J. C., Mason, A. J., McGlothlin, A., McGuinness, S., McQuilten, Z. K., McVerry, B. J., Mouncey, P. R., Murthy, S., Neal, M. D., Nichol, A. D., O'Kane, C. M., Young, I. S., McAuley, D. F. & REMAP-CAP Investigators, 23 Dec 2023, In: New England Journal of Medicine. 389, 25, p. 2341-2354 14 p.

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22 Citations (Scopus)

20 Downloads (Pure)

2022

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

Gorman, E. A., O'Kane, C. M. & McAuley, D. F., 01 Oct 2022, In: Lancet (London, England). 400, 10358, p. 1157-1170

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153 Citations (Scopus)

2116 Downloads (Pure)

Airwaves

Griffiths, M., O'Kane, C. M. & Quint, J. K., Sept 2022, In: Thorax. 77, 9, 1 p., 845.

Research output: Contribution to journal › Article

Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial

Boyle, A. J., Ferris, P., Bradbury, I., Conlon, J., Shankar-Hari, M., Rogers, A. J., O'Kane, C. M. & McAuley, D. F., 07 Jun 2022, In: Critical Care. 26, 1, 8 p., 164.

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16 Citations (Scopus)

44 Downloads (Pure)

Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome

McKelvey, M. C., Abladey, A. A., Small, D. M., Doherty, D. F., Williams, R., Scott, A., Spek, C. A., Borensztajn, K. S., Holsinger, L., Booth, R., O'Kane, C. M., McAuley, D. F., Taggart, C. C. & Weldon, S., 01 Apr 2022, In: American Journal of Respiratory and Critical Care Medicine. 205, 7, p. 769-782 14 p.

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17 Citations (Scopus)

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Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a randomised, triple-blind, allocation concealed, placebo-controlled phase 2 trial

Gorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M. & McAuley, D. F. & 1 others, O'Kane, C., 13 May 2022, In: Trials. 23, 401.

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5 Citations (Scopus)

58 Downloads (Pure)

The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial

McKelvey, M. C., Bradbury, I., McDowell, C., Calfee, C. S., Weldon, S., O’kane, C. M., McAuley, D. F. & Taggart, C. C., 01 Sept 2022, In: Critical Care and Resuscitation. 24, 3, p. 251-258 8 p.

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2021

Aspirin as a Treatment for Acute Respiratory Distress Syndrome: a randomised placebo controlled clinical trial

Toner, P., Boyle, A. J., McNamee, J. J., Callaghan, K., Nutt, C., Johnston, P., Trinder, J., McFarland, M., Verghis, R., McAuley, D. F. & O'Kane, C. M., 14 Nov 2021, (Early online date) In: Chest.

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15 Citations (Scopus)

167 Downloads (Pure)

Hyperoxaemia and hypoxaemia are associated with harm in patients with ARDS

Boyle, A. J., Holmes, D. N., Hackett, J., Gilliland, S., McCloskey, M., O'Kane, C. M., Young, P., Di Gangi, S. & McAuley, D. F., 08 Sept 2021, In: BMC Pulmonary Medicine. 21, 12 p., 285.

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9 Citations (Scopus)

101 Downloads (Pure)

Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS

Silva, J. D., Su, Y., Calfee, C. S., Delucchi, K. L., Weiss, D., McAuley, D. F., O'Kane, C. & Krasnodembskaya, A. D., 01 Jul 2021, In: European Respiratory Journal. 58, 1, 18 p., 2002978.

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141 Citations (Scopus)

136 Downloads (Pure)

Mesenchymal Stromal Cells: an Antimicrobial and Host-Directed Therapy for Complex Infectious Diseases

Shaw, T. D., Krasnodembskaya, A. D., Schroeder, G. N., Zumla, A., Maeurer, M. & O'Kane, C. M., 06 Oct 2021, (Early online date) In: Clinical Microbiology Reviews. 34, 4, e00064-21.

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20 Citations (Scopus)

189 Downloads (Pure)

Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial

Gorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Krasnodembskaya, A., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G. & Clarke, M. & 2 others, McAuley, D. F. & O'Kane, C. M., Nov 2021, In: EClinicalMedicine - published by THE LANCET. 41, 101167.

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26 Citations (Scopus)

55 Downloads (Pure)

Secreted Extracellular Cyclophilin A is a Novel Mediator of Ventilator Induced Lung Injury

Koh, M. W., Baldi, R. F., Soni, S., Handslip, R., Tan, Y. Y., O'Dea, K. P., Malesevic, M., McAuley, D. F., O'Kane, C. M., Patel, B. V., Takata, M. & Wilson, M. R., 13 Apr 2021, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.

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9 Citations (Scopus)

71 Downloads (Pure)

2020

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N. H., Conway Morris, A., Singh, S., Dark, P., Roy, A. I., Perkins, G. D., McMullan, R., Emerson, L., Blackwood, B., Wright, S. E., Kefala, K., O'Kane, C., Baudouin, S. V., Paterson, R. W., Rostron, A. J., Agus, A. & Bannard-Smith, J. & 19 others, Robin, N., Welters, I., Bassford, C., Yates, B., Spencer, C., Laha, S., Hulme, J., Bonner, S., Linnett, V. C., Sonksen, J., van den Broeck, T., Boschman, G., Keenan, J., Scott, J., Allen, A. J., Phair, G., Parker, J., Bowett, S. A. & Simpson, A. J., Feb 2020, In: The Lancet Respiratory Medicine. 8, 2, p. 182-191 10 p.

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65 Citations (Scopus)

187 Downloads (Pure)

Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials

Sinha, P., Delucchi, K. L., McAuley, D., O'Kane, C., Matthay, M. & Calfee, C. S., 13 Jan 2020, (Early online date) In: The Lancet Respiratory Medicine. 11 p.

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174 Citations (Scopus)

892 Downloads (Pure)

Emerging pharmacological therapies for ARDS COVID-19 and beyond

Horie, S., McNicholas, B., Rezoagli, E., Pham, T., Curley, G., McAuley, D., O'Kane, C., Nichol, A., Dos Santos, C., Rocco, P. R. M., Bellani, G. & Laffey, J. G., 11 Jul 2020, (Early online date) In: Intensive Care Medicine.

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59 Citations (Scopus)

77 Downloads (Pure)

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis and COVID 19 infection: optimising the therapeutic potential

Gorman, E., Millar, J., McAuley, D. & O'Kane, C., 11 Nov 2020, (Early online date) In: Expert Review of Respiratory Medicine.

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43 Citations (Scopus)

395 Downloads (Pure)

Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study

Sinha, P., Calfee, C. S., Cherian, S., Brealey, D., Cutler, S., King, C., Killick, C., Richards, O., Cheema, Y., Bailey, C., Reddy, K., Delucchi, K. L., Shankar-Hari, M., Gordon, A. C., Shyamsundar, M., O'Kane, C. M., McAuley, D. F. & Szakmany, T., 01 Dec 2020, In: The Lancet Respiratory Medicine. 8, 12, p. 1209-1218

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175 Citations (Scopus)

249 Downloads (Pure)

Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy - achieving global consensus and visibility for cellular host-directed therapies

Zumla, A., Wang, F.-S., Ippolito, G., Petrosillo, N., Agrati, C., Azhar, E. I., El-Kafrawy, S. A., Osman, M., Zitvogel, L., Locatelli, F., Gorman, E., O'Kane, C., Mcauley, D. & Maeurer, M., 17 May 2020, (Early online date) In: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

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44 Citations (Scopus)

99 Downloads (Pure)

Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial

Gorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M. & O'Kane, C. & 1 others, McAuley, D. F., 03 Jun 2020, In: Trials. 21, 1, p. 462

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23 Citations (Scopus)

55 Downloads (Pure)

Subphenotypes in critical care: translation into clinical practice

Reddy, K., Sinha, P., O'Kane, C., Gordon, A., Calfee, C. S. & McAuley, D., 01 Jun 2020, In: The Lancet Respiratory Medicine. 8, 6, p. 631-643 13 p.

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125 Citations (Scopus)

1381 Downloads (Pure)

2019

A porcine ex vivo lung perfusion model to investigate bacterial pathogenesis

Dumigan, A., Fitzgerald, M., Santos, J. S. P. G., Hamid, U., O’kane, C. M., McAuley, D. F. & Bengoechea, J. A., 01 Nov 2019, In: mBio. 10, 6, e02802-19.

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17 Citations (Scopus)

175 Downloads (Pure)

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: Re-analysis of three recent sepsis and ARDS randomised controlled trials

Santhakumaran, S., Gordon, A., Prevost, A. T., O'Kane, C., McAuley, D. F. & Shankar-Hari, M., 03 May 2019, In: Critical Care. 23, 1, 156.

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27 Citations (Scopus)

70 Downloads (Pure)

Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair

Fergie, N., Todd, N., McClements, L., McAuley, D., O'Kane, C. & Krasnodembskaya, A., 16 Jan 2019, (Early online date) In: The FASEB Journal. 14 p.

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37 Citations (Scopus)

306 Downloads (Pure)

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J. & Whyte, M. K. B. & 1 others, Walmsley, S. R., 08 Mar 2019, (Early online date) In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235

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40 Citations (Scopus)

92 Downloads (Pure)

2018

Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

Calfee, C. S., Delucchi, K. L., Sinha, P., Matthay, M. A., Hackett, J., Shankar-Hari, M., McDowell, C., Laffey, J. G., O'Kane, C. M., McAuley, D. F. & Irish Critical Care Trials Group, 01 Sept 2018, In: The Lancet Respiratory Medicine. 6, 9, p. 691-698 8 p.

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484 Citations (Scopus)

1562 Downloads (Pure)

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

LUNG SAFE Investigators, 27 Oct 2018, In: Critical Care. 22, 1, 14 p., 268.

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23 Citations (Scopus)

350 Downloads (Pure)

Novel anti-tumor necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury

Proudfoot, A., Bayliffe, A., O'Kane, C., Wright, T., Serone, A., Bareille, P., Brown, V., Hamid, U. I., Chen, Y., Wilson, R., Cordy, J., Morely, P., de Wildt, R., Elborn, S., Hind, M., Chilvers, E. R., Griffiths, M., Summers, C. & McAuley, D. F., 29 Jan 2018, (Early online date) In: Thorax. 73, 8, p. 723 8 p.

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68 Citations (Scopus)

385 Downloads (Pure)

Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial

Shyamsundar, M., O'Kane, C., Perkins, G. D., Kennedy, G., Campbell, C., Agus, A., Phair, G. & McAuley, D., 18 Dec 2018, In: Trials. 19, 1, p. 690

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2 Citations (Scopus)

267 Downloads (Pure)

2017

Aspirin reduces lipopolysaccharide induced pulmonary inflammation in human models of ARDS

Hamid, U., Krasnodembskaya, A., Fitzgerald, M., Shyamsundar, M., Kissenpfennig, A., Scott, C., Lefrancais, E., Mark R, L., Verghis, R., Scott, J., Simpson, A. J., McNamee, J., McAuley, D. & O'Kane, C. M., 12 Jan 2017, (Early online date) In: Thorax. 72, p. 971-980 10 p.

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62 Citations (Scopus)

828 Downloads (Pure)

Characterisation of eppin function: expression and activity in the lung

Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S., 13 Jul 2017, In: European Respiratory Journal. 50, 1, 1601937.

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5 Citations (Scopus)

202 Downloads (Pure)

Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction - a randomised placebo-controlled trial (KARE): study protocol

Cross, L. J. M., O'Kane, C. M., McDowell, C., Elborn, J. J., Matthay, M. A. & McAuley, D. F., 11 May 2017, In: Trials. 18, 1, p. 214

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1 Citation (Scopus)

182 Downloads (Pure)

Evidence for chemokine synergy during neutrophil migration in ARDS

Williams, A. E., Jose, R. J., Mercer, P. F., Brealey, D., Parekh, D., Thickett, D. R., O'Kane, C., McAuley, D. F. & Chambers, R. C., Jan 2017, In: Thorax. 72, 1, p. 66-73

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Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial

McAuley, D. F., Cross, L. M., Hamid, U., Gardner, E., Elborn, J. S., Cullen, K. M., Dushianthan, A., Grocott, M. P., Matthay, M. A. & O'Kane, C. M., 06 Jun 2017, In: The Lancet Respiratory Medicine. 5, 6, p. 484-491

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72 Citations (Scopus)

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Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer

Morrison, T. J., Jackson, M. V., Cunningham, E. K., Kissenpfennig, A., McAuley, D. F., O'Kane, C. M. & Krasnodembskaya, A. D., 15 Nov 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 10, p. 1275

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583 Citations (Scopus)

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Simvastatin for patients with acute respiratory distress syndrome long-term outcomes and cost-effectiveness from a randomised controlled trial

Agus, A., Hulme, C., Verghis, R. M., McDowell, C., Jackson, C., O'Kane, C., Laffey, J. G. & McAuley, D. F., 17 May 2017, In: Critical Care. 21, 108, 10 p.

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20 Citations (Scopus)

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Cecilia O'Kane

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