• Room 03.014 - Institute of Pathology Block 1 R.V.H. Site

    United Kingdom

1991 …2019
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Personal profile

Research Statement

My research aims are to monitor worldwide the increasing incidence of type 1 diabetes in childhood and to identify environmental risk factors which, if modifiable, could provide opportunities for the prevention of this disease.

I maintain the Northern Ireland Childhood Diabetes Register and am a co-ordinator of the EURODIAB collaboration of childhood diabetes registers. I have produced estimates for the number of children with type 1 diabetes worldwide for three editions of the International Diabetes Federation's Diabetes Atlas. I was a leader of the successful EURODIAB Substudy 2 case-control study of risk factors for childhood type 1 diabetes which, at the time it was conducted, was the largest such study of this disease and which identified many of its known environmental risk factors. Since then I have published several systematic reviews of early life risk factors for this disease.

I have provided statistical support for both case-control and family-based genetic epidemiology studies within the School. This work has resulted in collaborations with the GRID study and the MIGen Consortium into the genetics of type 1 diabetes and coronary disease, respectively, and these collaborations have lead to co-authorship of several publications in journals with the highest impact factors.

I have organised trial management and performed statistical analysis for several multicentre randomised controlled trials which have been lead by local investigators (CUROSURF4, OSECT, DAPIT).

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Type 1 Diabetes Mellitus Medicine & Life Sciences
Northern Ireland Medicine & Life Sciences
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Population Medicine & Life Sciences
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Randomized Controlled Trials Medicine & Life Sciences
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Projects 2007 2016

Research Output 1991 2019

A loyalty scheme to encourage physical activity in office workers: a cluster RCT

Hunter, R., Gough, A., Murray, J., Tang, J., Brennan, S., Chrzanowski-Smith, O., Carlin, A., Patterson, C., Longo, A., Hutchinson, W. G., Prior, L., Tully, M., French, D., Adams, J., McIntosh, E., Xin, Y. & Kee, F., Aug 2019, In : Public Health Research. 7, 15, 114 p.

Research output: Contribution to journalSpecial issue

Open Access
File
Workplace
Quality-Adjusted Life Years
Cost-Benefit Analysis
Absenteeism
Waiting Lists
Open Access
Mediterranean Diet
Northern Ireland
Oral Health
Health Status
Cardiovascular Diseases

Chronic periodontitis and reduced respiratory function

Winning, L., Patterson, C. C., Cullen, K. M., Kee, F. & Linden, G. J., 01 Mar 2019, In : Journal of Clinical Periodontology. 46, 3, p. 266-275 10 p.

Research output: Contribution to journalArticle

Chronic Periodontitis
C-Reactive Protein
Linear Models
Northern Ireland
Confounding Factors (Epidemiology)

Dietary patterns and hearing loss in older men enrolled in the Caerphilly Study

Gallagher, N. E., Patterson, C. C., Neville, C. E., Yarnell, J., Ben-Shlomo, Y., Fehily, A., Gallacher, J. E., Lyner, N. & Woodside, J. V., 23 Jan 2019, In : British Journal of Nutrition.

Research output: Contribution to journalArticle

Open Access
File

Effect of Moderate Red Wine versus Vodka Consumption on Inflammatory Markers Related to Cardiovascular Disease Risk: A Randomized Crossover Study

Wotherspoon, A., Elshahat, S., McAlinden, N., Dean, K., Young, I. S., Sharpe, P. C., Blankenburg, S., Patterson, C. C., McKinley, M. C., Evans, A. & Woodside, J. V., 26 Nov 2019, In : Journal of the American College of Nutrition. 6 p.

Research output: Contribution to journalArticle

Wine
Cross-Over Studies
Cardiovascular Diseases
Biomarkers
Blood Vessels

Activities 1989 2018

Cardiff University (External organisation)

Chris Patterson (Member)
20182020

Activity: Membership typesMembership of peer review panel or committee

Diabetes Atlas (8th edition)

Chris Patterson (Contributor)
2017

Activity: Consultancy typesContribution to the work of national or international committees and working groups

EURODIAB Collaborators Meeting, Innsbruck, 2017

Chris Patterson (Organiser)
19 Oct 2017

Activity: Participating in or organising an event typesParticipation in conference

World Health Organization (External organisation)

Chris Patterson (Advisor)
20172018

Activity: Membership typesMembership of peer review panel or committee

University of Cambridge (External organisation)

Chris Patterson (Member)
20172020

Activity: Membership typesMembership of peer review panel or committee

Impact

Improvements in clinical assessment and management of Difficult-to-treat Asthma in Adults

Liam Heaney (Participant), Michael Stevenson (Participant), Diarmuid McNicholl (Participant), Lorcan McGarvey (Participant), Joan Sweeney (Participant), Chris Patterson (Participant)

Impact: Health Impact, Quality of Life Impact

Protocols that assist clinicians to wean critically ill patients from mechanical ventilation in the intensive care unit (ICU)

Bronagh Blackwood (Participant), Chris Patterson (Participant), Linda Johnston (Participant), Fiona Alderdice (Participant), Christopher Cardwell (Participant), Peter O'Halloran (Participant), Danny McAuley (Participant)

Impact: Health Impact, Quality of Life Impact