• Room 03.003 - CCRCB

    United Kingdom

Accepting PhD Students

20002020
If you made any changes in Pure these will be visible here soon.

Personal profile

Interests

Nanomedicine, Antibodies, Antibody-Drug Conjugates (ADCs), cathepsin proteases, cancer, inflammation, infection

Research Statement

Professor Chris Scott is Acting Director of the Centre for Cancer Research and Cell Biology at Queen’s University Belfast.  Following a primary degree in Biochemistry he undertook a PhD and post doctoral training at Queen’s in molecular enzymology.  In 2001, Chris was one of the founding members of QUB spinout company Fusion Antibodies Ltd., before returning to Queen’s in 2003 to take up an academic position.  Chris is internationally renowned for his work in development of antibody and nanomedicine-based therapies for the treatment of cancer and other conditions.  Work in his laboratory is funded by agencies such as Medical Research Council, HSCNI, and various industrial sources such as AstraZeneca and Immunocore.  He also held a Royal Society Industrial Fellowship with GSK from 2012-15, and won the Vice Chancellor’s Prize for Innovation in 2015 with his group’s work on developing a novel nanomedicine for the treatment of sepsis and other inflammatory conditions. Chris is actively involved in nanomedicine across the UK and is a Trustee of the British Society of Nanomedicine.

Fingerprint Dive into the research topics where Christopher Scott is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 33 Similar Profiles
cathepsin S Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
asparaginylendopeptidase Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Antibodies Engineering & Materials Science
Cysteine Proteases Medicine & Life Sciences
Cathepsins Medicine & Life Sciences
Tumors Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2003 2020

Research Output 2000 2020

Drug delivery
Encapsulation
Polyethylene glycols
attachment
delivery

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications

Hill, M., Twigg, M., Sheridan, E. A., Hardy, J. G., Elborn, J. S., Taggart, C. C., Scott, C. J. & Migaud, M. E., 02 Aug 2019, In : Pharmaceutics. 11, 8, 12 p., 379.

Research output: Contribution to journalArticle

Open Access
File
Tobramycin
Chitosan
Mucus
Drug Delivery Systems
Cystic Fibrosis
54 Downloads (Pure)

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In : Journal of Oncology.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
Triple Negative Breast Neoplasms
Biomarkers
Neoplasms
DNA Repair

Identification and SAR exploration of a novel series of Legumain inhibitors

Eddie, S. L., Gregson, A., Graham, E., Burton, S., Harrison, T., Burden, R., Scott, C. J., Mullan, P. B. & Williams, R., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry Letters. 29, 12, p. 1546-1548 3 p.

Research output: Contribution to journalArticle

asparaginylendopeptidase
Dipeptides
Molecules
Research
Experiments
1 Citation (Scopus)
42 Downloads (Pure)

Oriented attachment of VNAR proteins, via site-selective modification, on PLGA-PEG nanoparticles enhances nanoconjugate performance

Nogueira, J. C. F., Greene, M. K., Richards, D. A., Furby, A. O., Steven, J., Porter, A., Barelle, C., Scott, C. J. & Chudasama, V., 27 Jun 2019, In : Chemical Communications. 55, 53, p. 7671-7674

Research output: Contribution to journalArticle

Open Access
File
glycolic acid
Nanoconjugates
Antigen Receptors
Lactic acid
Antigens

Activities 2017 2017

  • 1 Participation in conference
  • 1 KTP & Consultancy in kind

KTP/ Causeway Sensors Ltd - S2410CNR

Christopher Scott (Member), James Burrows (Member)
01 Apr 201731 Mar 2020

Activity: Consultancy typesKTP & Consultancy in kind

British Society of Nanomedicine

Jonathan Coulter (Member of the organising committee), Christopher Scott (Organiser)
10 Aug 201711 Aug 2017

Activity: Participating in or organising an event typesParticipation in conference