Cliff Taggart

Professor

  • Room 02.020 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Professor Taggart is open to wide-ranging PhD applications from candidates with a basic science or clinical background. His fields of interest include: - acute and chronic lung disease eg. Cystic Fibrosis (CF), Acute Respiratory Distress Syndrome (ARDS) and Chronic Obstructive Pulmonary Disease (COPD) - Respiratory Innate Immunity - Protease and protease inhibitor function in lung disease Previous research experience is desirable although not essential.

1994 …2020
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Personal profile

Research Statement

My research focuses on evaluating mechanisms of excessive inflammation in lung disease and how this may predispose to infection in the lung. My primary disease interests are Cystic Fibrosis, Chronic Obstructive Pulmonary Disease and Acute Respiratory Distress Syndrome. I am interested in how the innate immune response becomes dysregulated during excessive inflammation as a result of elevated protease activity. Findings from our group have been published in high-ranking Respiratory journals including the American Journal of Respiratory and Critical Care Medicine and the European Respiratory Journal. My research brings me in to contact with Pharma and Diagnostics companies, from whom I receive funding for translational studies. I have also been funded by the Medical Research Council, the Engineering and Physical Sciences Research Council, EU FP7, Innovate UK and the Cystic Fibrosis Foundation. I am actively involved in the European Respiratory Society (ERS) as a member of Assembly 3. In addition, I was previously the Chair and Secretary of the Airway Cell Biology group of ERS (2011-17) and currently serve as a member of the ERS College of Experts.

Research Focus

Respiratory Disease

Inflammation

Innate Immunity

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  • 9 Similar Profiles
Secretory Leukocyte Peptidase Inhibitor Medicine & Life Sciences
Cystic Fibrosis Medicine & Life Sciences
Lung Medicine & Life Sciences
Leukocyte Elastase Medicine & Life Sciences
Elafin Medicine & Life Sciences
cathepsin S Medicine & Life Sciences
Protease Inhibitors Medicine & Life Sciences
Peptide Hydrolases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2020

Research Output 1994 2019

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications

Hill, M., Twigg, M., Sheridan, E. A., Hardy, J. G., Elborn, J. S., Taggart, C. C., Scott, C. J. & Migaud, M. E., 02 Aug 2019, In : Pharmaceutics. 11, 8, 12 p., 379.

Research output: Contribution to journalArticle

Open Access
File
Tobramycin
Chitosan
Mucus
Drug Delivery Systems
Cystic Fibrosis

Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease

Brown, R., Paulsen, M., Schmidt, S., Schaterrny, J., Frank, A., Hirtz, S., Delaney, R., Doherty, D., Hagner, M., Taggart, C., Weldon, S. & Mall, M. A., 09 Sep 2019, In : American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journalArticle

Obstructive Lung Diseases
Pulmonary diseases
Interleukin-1 Receptors
Eosinophilia
Eosinophils
3 Citations (Scopus)
188 Downloads (Pure)

Protein Phosphatase 2A Reduces Cigarette Smoke-Induced Cathepsin S and Loss of Lung Function

Doherty, D. F., Nath, S., Poon, J., Foronjy, R. F., Ohlmeyer, M., Dabo, A. J., Salathe, M., Birrell, M., Belvisi, M., Baumlin, N., Kim, M. D., Weldon, S., Taggart, C. & Geraghty, P., 14 Jan 2019, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
Protein Phosphatase 2
Smoke
Tobacco Products
Chronic Obstructive Pulmonary Disease
4 Citations (Scopus)
103 Downloads (Pure)

Respiratory viral infection: A potential “missing link” in the pathogenesis of COPD

Linden, D., Guo-Parke, H., Coyle, P. V., Fairley, D., McAuley, D. F., Taggart, C. C. & Kidney, J., 31 Mar 2019, In : European Respiratory Review. 28, 151, 14 p., 180063.

Research output: Contribution to journalReview article

Open Access
File
Virus Diseases
Respiratory Tract Infections
Chronic Obstructive Pulmonary Disease
Disease Progression
Molecular Diagnostic Techniques
1 Citation (Scopus)
48 Downloads (Pure)

Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection

Carlile, S. R., Shiels, J., Kerrigan, L., Delaney, R., Megaw, J., Gilmore, B. F., Weldon, S., Dalton, J. P. & Taggart, C. C., 15 Apr 2019, In : Scientific Reports. 9, 9 p., 6071.

Research output: Contribution to journalArticle

Open Access
File
Elapidae
Pseudomonas aeruginosa
Pneumonia
Inflammation
Elapid Venoms

Prizes

Chair of the Airway Cell Biology Group, European Respiratory Society

Cliff Taggart (Recipient), 01 Oct 2014

Prize: Election to learned society

Member, European Respiratory Society College of Experts

Cliff Taggart (Recipient), 01 Dec 2017

Prize: Prize (including medals and awards)

Romain Pauwels Award

Cliff Taggart (Recipient), 05 Oct 2008

Prize: Prize (including medals and awards)

Pulmonary Medicine
Research

Secretary of the Airway Cell Biology Group, European Respiratory Society

Cliff Taggart (Recipient), 01 Oct 2011

Prize: Prize (including medals and awards)

Molecular Medicine
Molecular Biology

Activities 1997 2020

PhD External Examiner

Cliff Taggart (Examiner)
01 Jan 202001 Feb 2020

Activity: Examination typesPhD external examination

European Respiratory Society International Congress 2019

Cliff Taggart (Contributor)
28 Sep 201902 Oct 2019

Activity: Participating in or organising an event typesParticipation in conference

Work Experience/Work Shadowing AS/A level student

Cliff Taggart (Recipient)
17 Jun 201919 Jun 2019

Activity: Other activity typesHosting a school group or open day

PhD Internal Examiner

Cliff Taggart (Examiner)
09 May 2019

Activity: Examination typesOther examination

Publishing in the Journal of Cystic Fibrosis

Cliff Taggart (Invited speaker)
27 Mar 201930 Mar 2019

Activity: Talk or presentation typesInvited talk

Press / Media

Queen's University researchers make pneumonia breakthrough

Cliff Taggart

15/06/2018

3 Media contributions

Press/Media: Research

CF MATTERS

Cliff Taggart

01/10/2013

1 item of Media coverage

Press/Media: Research

DNA of Innovation Volume 1

Cliff Taggart

01/09/2011

1 Media contribution

Press/Media: Research

Romain Pauwels Award

Cliff Taggart

21/07/200822/07/2008

1 item of Media coverage, 2 Media contributions

Press/Media: Research