Projects per year
Personal profile
Research Statement
My research focuses on evaluating mechanisms of excessive inflammation in lung disease and how this may predispose to infection in the lung. My primary disease interests are Cystic Fibrosis, Chronic Obstructive Pulmonary Disease and Acute Respiratory Distress Syndrome. I am interested in how the innate immune response becomes dysregulated during excessive inflammation as a result of elevated protease activity. Findings from our group have been published in high-ranking Respiratory journals including the American Journal of Respiratory and Critical Care Medicine and the European Respiratory Journal. My research brings me in to contact with Pharma and Diagnostics companies, from whom I receive funding for translational studies. I have also been funded by the Medical Research Council, the Engineering and Physical Sciences Research Council, EU H2020, EU FP7, Innovate UK and the Cystic Fibrosis Foundation. I am actively involved in the European Respiratory Society (ERS) as a member of Assembly 3. In addition, I was previously the Chair and Secretary of the Airway Cell Biology group of ERS (2011-17) and currently serve as a member of the ERS College of Experts.
Research Focus
Respiratory Disease
Inflammation
Innate Immunity
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R1141CEM: The Role of Extracellular Proteasome in the acutely inflamed lung
Taggart, C., McAuley, D., O'Kane, C. & Weldon, S.
02/01/2020 → …
Project: Research
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R1126CII: New Strategies for the inhibition of Infection and Inflammation in Cystic Fibrosis Lung Disease <MED,PHARM>
Taggart, C., Elborn, S., Migaud, M. & Scott, C.
01/08/2009 → …
Project: Research
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R1938RPM: Protective effects of keratinocyte growth factor in a model of acute lung injury
01/08/2007 → …
Project: Research
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R5103CEM: MicroRNA evaluation of Rhinovirus infected Primary Bronchial Epithelium
Taggart, C., Lopez Campos, G. & Weldon, S.
15/04/2019 → 30/11/2021
Project: Research
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Airway epithelium senescence as a driving mechanism in COPD pathogenesis
Bateman, G., Guo-Parke, H., Rodgers, A. M., Linden, D., Bailey, M., Weldon, S., Kidney, J. C. & Taggart, C. C., 23 Jul 2023, In: Biomedicines. 11, 7, 14 p., 2072.Research output: Contribution to journal › Review article › peer-review
Open AccessFile20 Downloads (Pure) -
In vitro evaluation of the potential use of snake-derived peptides in the treatment of respiratory infections using inhalation therapy: A proof of concept study
Creane, S., Joyce, M., MacLoughlin, R., Weldon, S., Dalton, J. P. & Taggart, C. C., 01 Apr 2023, In: European Journal of Pharmaceutical Sciences. 183, 106398.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Tracheostomy in children is associated with neutrophilic airway inflammation
Powell, J., Powell, S., Mather, M. W., Beck, L., Nelson, A., Palmowski, P., Porter, A., Coxhead, J., Hedley, A., Scott, J., Rostron, A. J., Hellyer, T. P., Zaidi, F., Davey, T., Garnett, J. P., Agbeko, R., Ward, C., Stewart, C. J., Taggart, C. C., Brodlie, M., & 1 others , 20 Feb 2023, (Early online date) In: Thorax.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Valaciclovir for Epstein-Barr virus suppression in moderate-to-severe COPD: a randomized, double-blind, placebo-controlled trial
Linden, D. A., Guo-Parke, H., McKelvey, M. C., Einarsson, G. G., Lee, A. J., Fairley, D. J., Brown, V., Lundy, G., Campbell, C., Logan, D., McFarland, M., Singh, D., McAuley, D. F., Taggart, C. C. & Kidney, J. C., Sep 2023, In: Chest. 164, 3, p. 625-636 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Vascular risk factors for COVID-19 ARDS: endothelium, contact-kinin system
Bailey, M., Linden, D., Guo-Parke, H., Earley, O., Peto, T., McAuley, D. F., Taggart, C. & Kidney, J., 28 Jun 2023, In: Frontiers in Medicine. 10, 1208866.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure)
Datasets
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A Secretory Leukocyte Protease Inhibitor Variant with Improved Activity against Lung Infection
Taggart, C. (Creator), Queen's University Belfast, 01 Aug 2015
DOI: 10.17034/fc50c42f-51bc-4a8a-9888-52d3f24f43d0
Dataset
File
Prizes
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Chair of the Airway Cell Biology Group, European Respiratory Society
Taggart, Cliff (Recipient), 01 Oct 2014
Prize: Election to learned society
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Member, European Respiratory Society College of Experts
Taggart, Cliff (Recipient), 01 Dec 2017
Prize: Prize (including medals and awards)
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Romain Pauwels Award
Taggart, Cliff (Recipient), 05 Oct 2008
Prize: Prize (including medals and awards)
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Secretary of the Airway Cell Biology Group, European Respiratory Society
Taggart, Cliff (Recipient), 01 Oct 2011
Prize: Prize (including medals and awards)
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University of Heidelberg-EMBO Molecular Medicine Partnership Unit Review Panel
Taggart, Cliff (Recipient), 16 Feb 2016
Prize: Appointment
Activities
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Protease-antiprotease balance in Cystic Fibrosis
Cliff Taggart (Advisor)
09 Jun 2021 → 12 Jun 2021Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Evaluating a role for Cathepsin S in acute and chronic lung disease
Cliff Taggart (Advisor)
22 Feb 2021 → 24 Feb 2021Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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PhD External Examiner
Cliff Taggart (Examiner)
01 Jan 2020 → 01 Feb 2020Activity: Examination types › PhD external examination
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Work Experience/Work Shadowing AS/A level student
Cliff Taggart (Recipient)
02 Dec 2019 → 04 Dec 2019Activity: Other activity types › Hosting a school group or open day
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PhD Internal Examiner
Cliff Taggart (Examiner)
19 Nov 2019Activity: Examination types › Other examination
Press/Media
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Cathepsin S in Chronic Lung Disease
17/01/2019 → 13/03/2019
1 item of Media coverage, 2 Media contributions
Press/Media: Research
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Queen's University researchers make pneumonia breakthrough
15/06/2018
3 Media contributions
Press/Media: Research
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Romain Pauwels Award
21/07/2008 → 22/07/2008
1 item of Media coverage, 2 Media contributions
Press/Media: Research