Research output per year
Research output per year
Professor
Room 03.008 - Medical Biology Centre
United Kingdom
Accepting PhD Students
PhD projects
I will support research programs in all aspects of CF and bronchiectasis care, this could include clinical trials, pulmonary exacerbation exploration, microbiology and basic science mechanisms.
Research activity per year
My main clinical research interests are cystic fibrosis (CF) and bronchiectasis (BE). I work with a range of colleagues that includes, clinicians, allied health professionals, a clinical research team and basic scientists to create a translational research program. My focus is to optimise clinical response to established and new therapies. I lead an active CF/BE investigator-initiated and pharmaceutical-sponsored clinical trial program in Belfast. I link closely with the Northern Ireland Clinical Research Network (NICRN)-Respiratory Health and the Wellcome-Wolfson Clinical Research Facility (CRF). I am a Principal Investigator (PI) and Chief Investigator (CI) on a number of pivotal clinical trials which is supported by national and international collaborative research networks.
My research projects currently involve,
Research Leadership
I am the recent ex-Director of the European CF Society – Clinical Trial Network (CTN) (www.ecfs.eu/ctn) (2021-2023) which consists of 68 CF research centres in 20 European countries. I am a founding member of the European CF Investigator Trial Committee. I also lead large European investigator led clinical trials. Belfast is recognised as one of the leading CF clinical trial centres in Europe.
Our clinical research centre is also a member of the UK CF Trust Clinical Trials Accelerator Platform (CTAP) and I recently served as a member of the Research Scientific Oversight Board for the CF Trust.
I am a current member of the European CF Society Scientific Committee and a member of the UK CF Medical Association.
Clinical
I am a consultant respiratory physician specialising in CF and BE.
I qualified in medicine from QUB and my early clinical training and airways inflammation research took place in Belfast. I subsequently trained in respiratory medicine in Manchester and Brisbane. In 2006 I was appointed as a consultant in CF and Respiratory medicine in Bristol and a honorary Clinical Senior Lecturer in the Department of Cellular and Molecular Medicine at the University of Bristol. In 2008 I became the Centre Director of the Bristol Adult CF centre and Director of the Adult Cystic Fibrosis Regional (Severn) Network. I returned to Belfast in 2011.
I also lead a multidisciplinary bronchiectasis team and work with colleagues in the clinical immunology centre to provide a regional service for patients with structural lung disease, complex infections and immunodeficiency.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Downey, D. (Advisor)
Activity: Talk or presentation types › Invited or keynote talk at national or international conference
Downey, D. (Advisor)
Activity: Membership types › Membership of board
Downey, D. (Examiner)
Activity: Examination types › PhD external examination
Downey, D. (Participant)
Activity: Participating in or organising an event types › Participation in workshop, seminar, course
17/11/2019
1 Media contribution
Press/Media: Public Engagement Activities
05/11/2019
1 item of Media coverage
Press/Media: Public Engagement Activities
03/04/2017
1 Media contribution
Press/Media: Public Engagement Activities
Elborn, S. (Participant), Martin, L. (Participant), Downey, D. (Participant), Brockbank, S. (Participant) & Ennis, M. (Participant)
Impact: Health Impact, Quality of Life Impact