Accepting PhD Students

PhD projects

I will support research programs in all aspects of CF and bronchiectasis care, this could include clinical trials, pulmonary exacerbation exploration, microbiology and basic science mechanisms.

19992020

Research output per year

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Research Output

Abstract

Airborne Bacterial Contamination within an Outpatient Respiratory Clinic

J, M., O'Neill, K., Tunney, M., Downey, D., Rendall, J., Moore, J., Elborn, J. & Gilpin, D., 2015, p. S539-S540.

Research output: Contribution to conferenceAbstract

Article

A change in behaviour — getting the balance right for research and policy

O'Sullivan, M., Ryan, C., Downey, D. & Hughes, C. M., Oct 2016, In : International Journal of Clinical Pharmacy. 38, 5, p. 1027-31 5 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
159 Downloads (Pure)

Antimicrobial effect of dimethyl sulfoxide and N, N-Dimethylformamide on Mycobacterium abscessus: Implications for antimicrobial susceptibility testing

Kirkwood, Z. I., Millar, B. C., Downey, D. G. & Moore, J. E., 15 Jun 2018, In : International journal of mycobacteriology. 7, 2, p. 134-136 3 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
218 Downloads (Pure)

Antimycobacterial activity of nonantibiotics associated with the polypharmacy of cystic fibrosis (CF) against mycobacterium abscessus

Kirkwood, Z. I., Millar, B. C., Downey, D. G. & Moore, J. E., 05 Dec 2018, In : International journal of mycobacteriology. 7, 4, p. 358-360

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
132 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
24 Downloads (Pure)

A treatment evaluator tool to monitor the real-world effectiveness of inhaled aztreonam lysine in cystic fibrosis

Plant, B. J., Downey, D. G., Eustace, J. A., Gunaratnam, C., Haworth, C. S., Jones, A. M., McKone, E. F., Peckham, D. G., Ketchell, R. I. & Bilton, D., 06 Apr 2017, In : Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 7 p.

Research output: Contribution to journalArticle

Open Access
File
303 Downloads (Pure)

Biomarkers to monitor exacerbations in cystic fibrosis

Gray, R. D., Downey, D. & Taggart, C. C., 03 Apr 2017, In : Expert review of respiratory medicine. 11, 4, p. 255-257 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Biomedical Science in Brief

Moore, J. E., Shaw, A., Millar, B. C., Martin, S. L., Murphy, P. G., Downey, D. G., Ennis, M., Elborn, J. S., Xu, J., Moore, J. E., Murphy, P. G., Millar, B. C., Redmond, A. O. B., Elborn, J. S., Conroy, S., Morrish, N., Wassif, W. S., Mak, C. M., Pang, R. W. C., Tam, S. & 8 others, Windsor, J. S., Clark, C. G., Macfarlane, L., Abutaleb, A., Abed, E., Qasem, L., Memish, Z. A. & Hajeer, A. H., Jan 2004, In : British Journal of Biomedical Science. 61, 3, p. 146-147 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Closed circuit rebreathing to achieve inert gas wash-in for multiple breath wash-out

Horsley, A. R., O'Neill, K., Downey, D. G., Elborn, J. S., Bell, N. J., Smith, J. & Owers-Bradley, J., 09 Feb 2016, In : ERJ Open. 2, 1, 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
240 Downloads (Pure)

Community analysis and co-occurrence patterns in airway microbial communities during health and disease

Einarsson, G. G., Zhao, J., LiPuma, J. J., Downey, D. G., Tunney, M. M. & Elborn, J. S., 08 Jul 2019, In : ERJ Open. 5, 3, 11 p., 00128-2017.

Research output: Contribution to journalArticle

Open Access
File
89 Downloads (Pure)

Current pregnancy outcomes in women with cystic fibrosis

Burden, C., Ion, R., Chung, Y., Henry, A., Downey, D. G. & Trinder, J., Oct 2012, In : European Journal of Obstetrics, Gynaecology and Reproductive Biology. 164, 2, p. 142-145 4 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)
Open Access
File
7 Downloads (Pure)

Do veterinary antibiotics have efficacy against highly resistant Gram-negative pathogens from patients with cystic fibrosis?

Moore, J. E., Alcorn, M., Ara, W., Millar, B. C., McCaughan, J., Rendall, J. C., McNeilly, J., Kuribayashi, T., Yamamoto, S., Matsuda, M., Goldsmith, C. E., Elborn, J. S. & Downey, D. G., Jan 2015, In : International Journal of Antimicrobial Agents. 45, 1, p. 93-95 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
51 Citations (Scopus)

Efficacy of Pseudomonas aeruginosa eradication regimens in bronchiectasis

Vallières, E., Tumelty, K., Tunney, M. M., Hannah, R., Hewitt, O., Elborn, J. S. & Downey, D. G., 01 Apr 2017, In : European Respiratory Journal. 49, 4, 3 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
242 Downloads (Pure)

Eradication of Pseudomonas aeruginosa in adults with cystic fibrosis

Kenny, S. L., Shaw, T. D., Downey, D. G., Moore, J. E., Rendall, J. C. & Elborn, J. S., Aug 2014, In : BMJ Open Respiratory Research. 1, p. 1-7 e000021.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
142 Downloads (Pure)

Failure to conceive in women with CF is associated with pancreatic insufficiency and advancing age

Shteinberg, M., Lulu, A. B., Downey, D. G., Blumenfeld, Z., Rousset-Jablonski, C., Perceval, M., Colombo, A., Stein, N., Livnat, G., Gur, M., Bentur, L., Mussaffi, H., Blau, H., Sarouk, I., Dagan, A., Kerem, E., Aviram, M., Picard, E., Aliberti, S., Álvarez, A. & 5 others, Miranda, J. P., Polverino, E., Durieu, I., Stuart Elborn, J. & Cohen-Cymberknoh, M., 23 Oct 2018, In : Journal of Cystic Fibrosis. p. 1-7

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
95 Downloads (Pure)
7 Citations (Scopus)

Gram negative infections in cystic fibrosis: a review of preventative and treatment options

Addy, C., Caskey, S. & Downey, D., 29 Jan 2020, In : Expert Opinion on Orphan Drugs. 8, 1, p. 11-26 16 p.

Research output: Contribution to journalArticle

Highlights of the North American Cystic Fibrosis Conference 2008.

Downey, D., 2009, In : Journal of the Royal Society of Medicine. 102 Suppl 1, SUPPL.1, p. 18-22 5 p.

Research output: Contribution to journalArticle

How reliable are cough swabs for the detection of Pseudomonas aeruginosa in adult patients with cystic fibrosis?

Moore, J. E., McCaughan, J., McNeilly, J., Rendall, J. C. & Downey, D. G., 2015, In : British Journal of Biomedical Science. 72, 4, p. 206

Research output: Contribution to journalArticle

Improved culture detection of Staphylococcus aureus from sputum of patients with cystic fibrosis (CF)

Wen, H., Stirling, J., McCaughan, J., Schock, B., Downey, D. G., Ennis, M. & Moore, J. E., 13 Oct 2019, In : Journal of Clinical Pathology. jclinpath-2019-206059

Research output: Contribution to journalArticle

Increased susceptibility to antibiotics in Gram-negative and Gram-positive pathogens, including Pseudomonas aeruginosa, at lower temperature: is antibiotic resistance reversal possible?

Moore, J. E., Moore, P. J. A., Downey, D., Millar, B. C., Coulter, W. A. & Goldsmith, C. E., 2013, In : British Journal of Biomedical Science. 70, 4, p. 173-174 2 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
186 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
139 Downloads (Pure)

Lack of Association Between Haptoglobin Phenotype and Cystic Fibrosis Outcomes

Shteinberg, M., Rivlin, J., Gur, M., Konopnicki, M., Stein, N., Tunney, M. M., Elborn, J. S., Downey, D. G., Johnston, E., Shalom, H. & Levy, A., Dec 2015, In : Lung. 193, 6, p. 1017-1021 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lung clearance index in adults and children with cystic fibrosis

O'Neill, K., Tunney, M. M., Johnston, E., Rowan, S., Downey, D. G., Rendall, J., Reid, A., Bradbury, I., Elborn, J. S. & Bradley, J. M., 06 Jul 2016, In : Chest. 150, 6, p. 1323-1332 10 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
338 Downloads (Pure)

Lung function and disease severity in cystic fibrosis patients heterozygous for p.Arg117His

Shteinberg, M., Downey, D. G., Beattie, D., McCaughan, J., Reid, A., Stein, N. & Elborn, J. S., 01 Feb 2017, In : ERS Monograph. 3, 1, 00056-2016.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
1974 Downloads (Pure)

Microbial ecology of the cystic fibrosis lung: does microflora type influence microbial loading?

Moore, J. E., Shaw, A., Millar, B. C., Downey, D. G., Murphy, P. G. & Elborn, J., 2005, In : British Journal of Biomedical Science. 62(4), 4, p. 175-178 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Microscopic Polyangitis secondary to Mycobacterium abscessus in a patient with Bronchiectasis: A case report

Addy, C., Doran, G., Jones, A. L., Wright, G., Caskey, S. & Downey, D., 19 Nov 2018, In : BMC Pulmonary Medicine. 18, 170

Research output: Contribution to journalArticle

Open Access
File
113 Downloads (Pure)

MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis

Vallières, E., Rendall, J. C., Moore, J. E., McCaughan, J., Hoeritzauer, A. I., Tunney, M. M., Elborn, J. S. & Downey, D. G., 31 Mar 2016, In : ERJ Open. 2, 1, 00064-2015.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
224 Downloads (Pure)

Neutrophils in cystic fibrosis

Downey, D., Jan 2009, In : Thorax. 64, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)

Nitric oxide, iNOS, and inflammation in cystic fibrosis.

Downey, D., Feb 2000, In : Journal of Pathology. 190, 2, p. 115-116 2 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Overview of the Pharmacological Treatment of Cystic Fibrosis

Gilpin, D., Tunney, M., Downey, D. & Elborn, S., 2013, Hospital Pharmacy Journal.

Research output: Contribution to specialist publicationArticle

Pathogen eradication” and “Emerging pathogens”: Difficult definitions in cystic fibrosis

Gilligan, P. H., Downey, D. G., Elborn, J. S., Flume, P. A., Funk, S., Gilpin, D., Kidd, T. J., McCaughan, J., Millar, B. C., Murphy, P. G., Rendall, J. C., Tunney, M. M. & Moore, J. E., 06 Jun 2018, In : Journal of Clinical Microbiology. p. 1-23

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
57 Downloads (Pure)

Pharmacists' perspectives on monitoring adherence to treatment in Cystic Fibrosis

Mooney, K., Ryan, C. & Downey, D. G., Apr 2016, In : International Journal of Clinical Pharmacy. 38, 2, p. 296-302 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Phase II trial to assess the biochemical efficacy of transgenic alpha1-anti-trypsin as an effective treatment of cystic fibrosis

Martin, L., Downey, D., Elborn, J. S., Bilton, D., Keogan, M. T. & Edgar, J., 01 Dec 1999, In : Thorax. 54, SUPPL. 3

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pseudomonas aeruginosa displays an altered phenotype in vitro when grown in the presence of mannitol

Moore, J. E., Rendall, J. C. & Downey, D. G., 2015, In : British Journal of Biomedical Science. 72, 3, p. 115-119

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
File
2 Citations (Scopus)
136 Downloads (Pure)
1 Citation (Scopus)

Relative resistance index (RRI) - a scoring system for antibiotic resistance in Pseudomonas aeruginosa

Ewing, J. C., McCaughan, J., Moore, J., Fairley, D., Sutherland, B., Reid, A. & Downey, D., 26 Jul 2017, In : British Journal of Biomedical Science. 5 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
3557 Downloads (Pure)

Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis.

Martin, L., Downey, D., Bilton, D., Keogan, M. T., Edgar, J. & Elborn, J., Feb 2006, In : Pediatric Pulmonology. 41, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Safety of sputum induction.

Downey, D., 2000, In : Chest. 118(1), p. 276 1 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)