• Room 02.057 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Professor McAuley is open to PhD applications from candidates with a basic science or clinical background. His major interest is the Acute Respiratory Distress Syndrome (ARDS). My research strategy in ARDS is to investigate potential novel therapeutic agents in ARDS in vitro, in vivo in human models of ARDS and in phase 2 clinical trials to inform subsequent phase 3 clinical trials. I am currently investigating the role of MSCs, statins and ECCO2R in ARDS. My other current research interests are patient stratification in ARDS, sepsis diagnostics and delirium. Previous research experience is desirable although not essential.

19972020

Research output per year

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Personal profile

Interests

Prof Danny McAuley is Professor and Consultant in Intensive Care Medicine at the Royal Victoria Hospital and Queen’s University of Belfast.

He is Co-Director of Research for the Intensive Care Society. His major research area is the acute respiratory distress syndrome.

Research Statement

My major interest is the Acute Respiratory Distress Syndrome (ARDS). My research strategy in ARDS is to investigate potential novel therapeutic agents in ARDS in vitro, in vivo in a human LPS model of ARDS and in phase 2 clinical trials to inform subsequent phase 3 clinical trials. My roles as the UK Intensive Care Society Co-Director of Research and the NICRN (Critical Care) clinical lead, mean I am well placed to develop the novel therapeutic targets into phase 3 clinical trials. I am currently investigating the role of statins, aspirin and extracorporeal carbon dioxide removal in ARDS.

I am also currently investigating MSCs, oncostatin M and anti-microbial peptides with a view to developing these agents as potential therapeutic agents for ARDS.

My other current research interests are nosocomial infection, sepsis diagnostics, delirium in critical illness and interventions to enhance recovery from critical illness.

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Projects

Research Output

  • Fool’s gold? Why blinded trials are not always best

    Anand, R., Bradley, J., Clarke, M., McAuley, D. & Norrie, J., 21 Jan 2020, In : The BMJ. 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 112 Downloads (Pure)
    Open Access
    File
  • 27 Downloads (Pure)

    A Core Outcome Set for Critical Care Ventilation Trials

    Blackwood, B., Ringrow, S., Clarke, M., Marshall, J. C., Connolly, B., Rose, L. & McAuley, D. F., 25 Jul 2019, In : Critical Care Medicine.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    100 Downloads (Pure)

    A porcine ex vivo lung perfusion model to investigate bacterial pathogenesis

    Dumigan, A., Fitzgerald, M., Santos, J. S. P. G., Hamid, U., O’kane, C. M., McAuley, D. F. & Bengoechea, J. A., 01 Nov 2019, In : mBio. 10, 6, e02802-19.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 43 Downloads (Pure)

    Activities

    • 2 Participation in workshop, seminar, course
    • 1 Participation in conference

    Lewis J Hurwitz Memorial Lecture: Howard Bauchner

    Aidan Cole (Organiser), Danny McAuley (Programme chair), Emma Cunningham (Organiser)
    15 Jan 2020

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

    Clinical Academic Forum

    Aidan Cole (Organiser), Danny McAuley (Chair), Emma Cunningham (Organiser), Richard Turkington (Participant), Cecilia O'Kane (Participant)
    15 Jan 2019

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

    UK Critical Care Research Forum

    Cecilia O'Kane (Organiser), Murali Shyamsundar (Organiser), Bronagh Blackwood (Organiser), Danny McAuley (Organiser)
    07 Jun 201808 Jun 2018

    Activity: Participating in or organising an event typesParticipation in conference

    Impact

    Protocols that assist clinicians to wean critically ill patients from mechanical ventilation in the intensive care unit (ICU)

    Bronagh Blackwood (Participant), Chris Patterson (Participant), Linda Johnston (Participant), Fiona Alderdice (Participant), Christopher Cardwell (Participant), Peter O'Halloran (Participant), Danny McAuley (Participant)

    Impact: Health Impact, Quality of Life Impact

    Thesis

    The role of lipid A in the virulence of ESKAPE pathogens

    Author: Bartholomew, T., 2019

    Supervisor: Bengoechea, J. (Supervisor), McAuley, D. (Supervisor) & Krasnodembskaya, A. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy