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    United Kingdom

Accepting PhD Students

19972019
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Personal profile

Interests

Prof Danny McAuley is Professor and Consultant in Intensive Care Medicine at the Royal Victoria Hospital and Queen’s University of Belfast.

He is Co-Director of Research for the Intensive Care Society. His major research area is the acute respiratory distress syndrome.

Research Statement

My major interest is the Acute Respiratory Distress Syndrome (ARDS). My research strategy in ARDS is to investigate potential novel therapeutic agents in ARDS in vitro, in vivo in a human LPS model of ARDS and in phase 2 clinical trials to inform subsequent phase 3 clinical trials. My roles as the UK Intensive Care Society Co-Director of Research and the NICRN (Critical Care) clinical lead, mean I am well placed to develop the novel therapeutic targets into phase 3 clinical trials. I am currently investigating the role of statins, aspirin and extracorporeal carbon dioxide removal in ARDS.

I am also currently investigating MSCs, oncostatin M and anti-microbial peptides with a view to developing these agents as potential therapeutic agents for ARDS.

My other current research interests are nosocomial infection, sepsis diagnostics, delirium in critical illness and interventions to enhance recovery from critical illness.

Fingerprint Dive into the research topics where Danny McAuley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2019

Research Output 1997 2019

A Core Outcome Set for Critical Care Ventilation Trials

Blackwood, B., Ringrow, S., Clarke, M., Marshall, J. C., Connolly, B., Rose, L. & McAuley, D. F., 25 Jul 2019, In : Critical Care Medicine.

Research output: Contribution to journalArticle

Open Access
File
Delphi Technique
Ventilation
Clinical Trials
Critical Care
Artificial Respiration

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

Pan, X., Cunningham, E. L., Passmore, A. P., McGuinness, B., McAuley, D. F., Beverland, D., O'Brien, S., Mawhinney, T., Schott, J. M., Zetterberg, H. & Green, B. D., 12 Mar 2019, In : Scientific Reports. 9, 1, 9 p., 4191.

Research output: Contribution to journalArticle

Open Access
File
Putrescine
Spermidine
Delirium
Glutamine
Orthopedics

Development and Validation of Parsimonious Algorithms to Classify ARDS Phenotypes: Secondary Analyses of Randomised Controlled Trials

Sinha, P., Delucchi, K. L., McAuley, D., O'Kane, C., Matthay, M. & Calfee, C. S., 01 Aug 2019, (Accepted) In : The Lancet Respiratory Medicine.

Research output: Contribution to journalArticle

Randomized Controlled Trials
Phenotype
Logistic Models
Bicarbonates
Protein C
1 Citation (Scopus)

Diabetic macular oedema and diode subthreshold micropulse laser (DIAMONDS): study protocol for a randomised controlled trial

DIAMONDS Study Group, 12 Feb 2019, In : Trials. 20, 11 p., 122.

Research output: Contribution to journalArticle

Open Access
File
Macular Edema
Lasers
Randomized Controlled Trials
Cost-Benefit Analysis
Visual Acuity

Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And new vesseLs in Diabetic retinopathy (EMERALD)

EMERALD Study Group, 28 Jun 2019, In : BMJ Open. 9, 6, 8 p., e027795.

Research output: Contribution to journalArticle

Open Access
File
Multimodal Imaging
Papilledema
Diabetic Retinopathy
Macular Edema
Cost-Benefit Analysis

Activities 2018 2018

  • 1 Participation in conference

UK Critical Care Research Forum

Cecilia O'Kane (Organiser), Murali Shyamsundar (Organiser), Bronagh Blackwood (Organiser), Danny McAuley (Organiser)
07 Jun 201808 Jun 2018

Activity: Participating in or organising an event typesParticipation in conference

Impact

Protocols that assist clinicians to wean critically ill patients from mechanical ventilation in the intensive care unit (ICU)

Bronagh Blackwood (Participant), Chris Patterson (Participant), Linda Johnston (Participant), Fiona Alderdice (Participant), Christopher Cardwell (Participant), Peter O'Halloran (Participant), Danny McAuley (Participant)

Impact: Health Impact, Quality of Life Impact

Thesis

The role of lipid A in the virulence of ESKAPE pathogens

Author: Bartholomew, T., 2019

Supervisor: Bengoechea, J. (Supervisor), McAuley, D. (Supervisor) & Krasnodembskaya, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy