Danny McAuley

2024

An international survey of the management of atrial fibrillation in critically unwell patients

Johnston, B. W., Udy, A. A., McAuley, D. F., Mogk, M., Welters, I. D. & Sibley, S., 01 Apr 2024, In: Critical Care Explorations. 6, 4, 10 p., e1069.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Citations (Scopus)

19 Downloads (Pure)

A randomized control trial evaluating the advice of a physiological-model/digital twin-based decision support system on mechanical ventilation in patients with acute respiratory distress syndrome

Patel, B. V., Mumby, S., Johnson, N., Handslip, R., Patel, S., Lee, T., Andersen, M. S., Falaschetti, E., Adcock, I. M., McAuley, D. F., Takata, M., Staudinger, T., Karbing, D. S., Jabaudon, M., Schellongowski, P., Rees, S. E. & DeVENT Study Group, 30 Oct 2024, In: Frontiers in Medicine. 11, 1473629.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Downloads (Pure)

Assessment and report of individual symptoms in studies of delirium in postoperative populations: a systematic review

Bowman, E. M. L., Sweeney, A. M., McAuley, D. F., Cardwell, C., Kane, J., Badawi, N., Jahan, N., Iqbal, H. K., Mitchell, C., Ballantyne, J. A. & Cunningham, E. L., Apr 2024, In: Age and Ageing. 53, 4, 14 p., afae077.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

29 Downloads (Pure)

Cell-based therapies for ARDS - Where are we now?

Curley, G. F., O'Kane, C. M., McAuley, D. F., Matthay, M. A. & Laffey, J. G., 07 Feb 2024, (Early online date) In: American Journal of Respiratory and Critical Care Medicine. 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

4 Citations (Scopus)

72 Downloads (Pure)

Cohort profile: post-hospitalisation COVID-19 (PHOSP-COVID) study

Elneima, O., McAuley, H. J. C., Leavy, O. C., Chalmers, J. D., Horsley, A., Ho, L.-P., Marks, M., Poinasamy, K., Raman, B., Shikotra, A., Singapuri, A., Sereno, M., Heaney, L. G., McGarvey, L., Baillie, J. K., Siddiqui, S., Beggs, M., Wilkinson, D., Armour, C. & McAuley, D. F. & 10 others, Peto, T., Scott, J. T., Brown, V., Drain, S., Robinson, L., Bell, D., Beggs, M., Wilson, I., Sharma, M. & PHOSP-COVID Study Collaborative Group, Feb 2024, In: International Journal of Epidemiology. 53, 1, 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

24 Downloads (Pure)

Communication in critical care tracheostomy patients dependent upon cuff inflation: a scoping review

McClintock, C., McAuley, D. F., McIlmurray, L., Alnajada, A. A. R., Connolly, B. & Blackwood, B., Nov 2024, In: Australian Critical Care. 37, 6, p. 971-984 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

1 Citation (Scopus)

23 Downloads (Pure)

Drug therapy versus placebo or usual care for comatose survivors of cardiac arrest; a systematic review with meta-analysis

McGuigan, P. J., Pauley, E., Eastwood, G., Hays, L. M. C., Jakobsen, J. C., Moseby-Knappe, M., Nichol, A. D., Nielsen, N., Skrifvars, M. B., Blackwood, B. & McAuley, D. F., Dec 2024, In: Resuscitation. 205, 13 p., 110431.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Downloads (Pure)

Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis

Kenny, G., Saini, G., Gaillard, C. M., Negi, R., Alalwan, D., Garcia Leon, A., McCann, K., Tinago, W., Kelly, C., Cotter, A. G., de Barra, E., Horgan, M., Yousif, O., Gautier, V., Landay, A., McAuley, D., Feeney, E. R., O'Kane, C. & Mallon, P. W., 15 Aug 2024, In: Heliyon. 10, 15, e34694.

Research output: Contribution to journal › Article › peer-review

Open Access

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9 Downloads (Pure)

Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis: the EASI-SWITCH RCT

Coyle, V., Forde, C., Adams, R., Agus, A., Barnes, R., Chau, I., Clarke, M., Doran, A., Grayson, M., McAuley, D., McDowell, C., Phair, G., Plummer, R., Storey, D., Thomas, A., Wilson, R. & McMullan, R., 01 Mar 2024, In: Health Technology Assessment. 28, 14, p. 1-101 101 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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33 Downloads (Pure)

Early switch to oral antibiotic therapy in patients with low-risk neutropenic sepsis (EASI-SWITCH): a randomized non-inferiority trial

EASI-SWITCH Investigators, Jan 2024, In: Clinical Microbiology and Infection. 30, 1, p. 92-99 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

4 Citations (Scopus)

47 Downloads (Pure)

Mechanical stretch induces senescence of lung epithelial cells and drives fibroblast activation by paracrine mechanisms

Martín-Vicente, P., López-Martínez, C., López-Alonso, I., Exojo-Ramírez, S. M., Duarte-Herrera, I. D., Amado-Rodríguez, L., Ordoñez, I., Cuesta-Llavona, E., Gómez, J., Campo, N., O'Kane, C. M., McAuley, D. F., Huidobro, C. & Albaiceta, G. M., 12 Aug 2024, (Early online date) In: American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journal › Article › peer-review

Neutrophil-derived proteases in lung inflammation: old players and new prospects

Cheetham, C. J., McKelvey, M. C., McAuley, D. F. & Taggart, C. C., 17 May 2024, In: International Journal of Molecular Sciences. 25, 10, 23 p., 5492.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

2 Citations (Scopus)

20 Downloads (Pure)

Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes

Antcliffe, D. B., Mi, Y., Santhakumaran, S., Burnham, K. L., Prevost, A. T., Ward, J. K., Marshall, T. J., Bradley, C., Al-Beidh, F., Hutton, P., McKechnie, S., Davenport, E. E., Hinds, C. J., O'Kane, C. M., McAuley, D. F., Shankar-Hari, M., Gordon, A. C. & Knight, J. C., 20 May 2024, In: Thorax. 79, 6, p. 515-523

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

8 Downloads (Pure)

Physiologic determinants of near-infrared spectroscopy-derived cerebral and tissue oxygen saturation measurements in critically ill patients

Cody, N., Bradbury, I., McMullan, R. R., Quinn, G., O’Neill, A., Ward, K., McCann, J., McAuley, D. F. & Silversides, J. A., May 2024, In: Critical Care Explorations. 6, 5, 9 p., e1094.

Research output: Contribution to journal › Article › peer-review

Open Access

File

18 Downloads (Pure)

Recovery following discharge from intensive care: what do patients think is helpful and what services are missing?

O’Neill, B., Green, N., Blackwood, B., McAuley, D., Moran, F., MacCormac, N., Johnston, P., McNamee, J. J., Shevlin, C. & Bradley, J., 18 Mar 2024, In: PLoS One. 19, 3, 12 p., e0297012.

Research output: Contribution to journal › Article › peer-review

Open Access

File

50 Downloads (Pure)

SIGNET: protocol for a multicentre, single-blind prospective, group sequential, randomised controlled trial to evaluate the benefits of a single dose of simvastatin given to potential organ donors declared dead by neurological criteria on outcomes in organ recipients

Evans, A., Mawson, P., Thomas, H., Keen, K., Watson, C. J., McAuley, D. F., MacGowan, G. A., Sheerin, N. S., Fisher, A., Shaw, J., Yates, H., Fallow, A., Kounali, D., Banks, J., Stevens, M., Paul, R., Hodge, R., Lawson, E., Harvey, D. & Dark, J., 18 Sept 2024, In: BMJ Open. 14, 9, 8 p., e086352.

Research output: Contribution to journal › Article › peer-review

Open Access

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Small volume fluid resuscitation and supplementation with 20% albumin versus buffered crystalloids in adults with septic shock: A protocol for a randomised feasibility trial

Bannard-Smith, J., Bellomo, R., Felton, T. W., McAuley, D. F., Kitchen, G. B., Fullwood, C., Thompson, A. & Dark, P. M., 18 Oct 2024, (Early online date) In: Journal of the Intensive Care Society.

Research output: Contribution to journal › Article › peer-review

Statistical power and performance of strategies to analyze composites of survival and duration of ventilation in clinical trials

Chen, Z., Harhay, M. O., Fan, E., Granholm, A., McAuley, D. F., Urner, M., Yarnell, C. J., Goligher, E. C. & Heath, A., 20 Sept 2024, In: Critical Care Explorations. 6, 10, e1152.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (Scopus)

5 Downloads (Pure)

The effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal compared with conventional lung protective ventilation on cardiac function

McGuigan, P. J., Bowcock, E. M., Barrett, N. A., Blackwood, B., Boyle, A. J., Cadamy, A. J., Camporota, L., Conlon, J., Cove, M. E., Gillies, M. A., McDowell, C., McNamee, J. J., O'Kane, C. M., Puxty, A., Sim, M., Parsons-Simmonds, R., Szakmany, T., Young, N., Orde, S. & McAuley, D. F., 01 Jan 2024, In: Critical Care Explorations. 6, 1, 13 p., e1028.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (Scopus)

28 Downloads (Pure)

The role of Proprotein Convertase Subtilisin-Kexin type 9 in the Acute Respiratory Distress Syndrome

Crossley, E., Hamilton, P., Silversides, J., McAuley, D. & O'Kane, C., 12 Aug 2024, (Accepted).

Research output: Contribution to conference › Poster › peer-review

Open Access

File

TRPV2 modulates mechanically induced ATP release from human bronchial epithelial cells

Dunne, O. M., Martin, S. L., Sergeant, G. P., McAuley, D. F., O’Kane, C. M., Button, B., McGarvey, L. P. & Lundy, F. T., 27 Apr 2024, In: Respiratory Research. 25, 10 p., 188.

Research output: Contribution to journal › Article › peer-review

Open Access

File

11 Downloads (Pure)

Use of landiolol for patients with septic shock and organ failure-Reply

Whitehouse, T., Lall, R., McAuley, D. F. & STRESS-L Collaborators, 27 Feb 2024, In: JAMA. 331, 8, p. 705-706 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Use of modified Berlin criteria in identifying patients with acute respiratory distress syndrome: a single-centre retrospective cohort study

Thompson, J. H., Reddy, K., Matthay, M. A., McAuley, D. F., Simpson, A. J. & Rostron, A. J., 01 Sept 2024, In: British Journal of Anaesthesia. 133, 3, p. 700-703 4 p.

Research output: Contribution to journal › Letter › peer-review

Vascular leak in sepsis: physiological basis and potential therapeutic advances

McMullan, R. R., McAuley, D. F., O'Kane, C. M. & Silversides, J. A., 23 Mar 2024, In: Critical Care. 28, 15 p., 97.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

6 Citations (Scopus)

85 Downloads (Pure)

Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses

Mumin, M. A., McKenzie, C. A., Page, V. J., Hadfield, D., Aitken, L. M., Hanks, F., Cunningham, E., Blackwood, B., Van Dellen, E., Slooter, A. J. C., Grocott, M. P. W., McAuley, D. F. & Spronk, P. E., 08 Feb 2024, (Early online date) In: International Journal of Clinical Pharmacy. 8 p.

Research output: Contribution to journal › Article › peer-review

2023

Acute hypoxaemic respiratory failure after treatment with lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal: long-term outcomes from the REST randomised trial

Boyle, A. J., McDowell, C., Agus, A., Logan, D., Stewart, J. D., Jackson, C., Mills, J., McNamee, J. J. & McAuley, D. F., 01 Aug 2023, In: Thorax. 78, 8, p. 767-774 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

39 Downloads (Pure)

Advancing specificity in delirium: the delirium subtyping initiative

Bowman, E. M. L., Brummel, N. E., Caplan, G. A., Cunningham, C., Evered, L. A., Fiest, K. M., Girard, T. D., Jackson, T. A., LaHue, S. C., Lindroth, H. L., Maclullich, A. M. J., McAuley, D. F., Oh, E. S., Oldham, M. A., Page, V. J., Pandharipande, P. P., Potter, K. M., Sinha, P., Slooter, A. J. C. & Sweeney, A. M. & 5 others, Tieges, Z., Van Dellen, E., Wilcox, M. E., Zetterberg, H. & Cunningham, E. L., 31 Jul 2023, (Early online date) In: Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

54 Downloads (Pure)

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK

Walsh, T. S., Aitken, L. M., McKenzie, C. A., Boyd, J., Macdonald, A., Giddings, A., Hope, D., Norrie, J., Weir, C., Parker, R. A., Lone, N. I., Emerson, L., Kydonaki, K., Creagh-Brown, B., Morris, S., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C. & Perkins, G. & 5 others, Reade, M., Blackwood, B., MacLullich, A., Glen, R. & Page, V. J., 10 Dec 2023, In: BMJ Open. 13, 12, p. e078645 53 p., e078645.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

40 Downloads (Pure)

A mechanistic analysis of the effect of valaciclovir for EBV suppression on airway inflammation and microbiome in COPD

Linden, D., Guo-Parke, H., Einarsson, G., Carson, S., Lee, A., Fairley, D., Singh, D., Tunney, M., Mcauley, D., Taggart, C. & Kidney, J., 19 May 2023, In: ERJ Open Research. 9, Suppl. 10, 1 p., 59.

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

A reply to analysis of static parameters in retrospective studies: limitations and interpretation

McGuigan, P. J., Giallongo, E., Nichol, A. D., Skrifvars, M. B. & McAuley, D. F., 02 Nov 2023, (Early online date) In: Critical Care. 27, 2 p., 423.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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10 Downloads (Pure)

A user evaluation of speech/phrase recognition software in critically ill patients: a DECIDE-AI feasibility study

Musalia, M., Lala, S., Cazalilla-Chica , L., Allan, J., Roach, L., Twamley, J., Nanda, S., Verlander, M., Williams, A., Kempe, I., Patel, I., Campbell-West, F., Blackwood, B. & McAuley, D. F., 10 Jul 2023, In: Critical Care. 27, 6 p., 277.

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

32 Downloads (Pure)

biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial

Dark, P., Perkins, G. D., McMullan, R., McAuley, D., Gordon, A. C., Clayton, J., Mistry, D., Young, K., Regan, S., McGowan, N., Stevenson, M., Gates, S., Carlson, G. L., Walsh, T., Lone, N. I., Mouncey, P. R., Singer, M., Wilson, P., Felton, T. & Marshall, K. & 2 others, Hossain, A. M. & Lall, R., 25 Apr 2023, (Early online date) In: Journal of the Intensive Care Society.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Correction: Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the role of active deresuscitation after resuscitation-2 (RADAR-2) randomised clinical trial

Silversides, J. A., McMullan, R., Emerson, L. M., Bradbury, I., Bannard-Smith, J., Szakmany, T., Trinder, J., Rostron, A. J., Johnston, P., Ferguson, A. J., Boyle, A. J., Blackwood, B., Marshall, J. C. & McAuley, D. F., Nov 2023, In: Intensive Care Medicine. 49, p. 1440 1 p.

Research output: Contribution to journal › Comment/debate

Delivery of a novel intervention to facilitate liberation from mechanical ventilation in paediatric intensive care: a process evaluation

Jordan, J., Tume, L., Clarke, M., McAuley, D., McDowell, C., McIlmurray, L., Morris, K., Peters, M., Walsh, T. & Blackwood, B., 27 Nov 2023, In: PLoS One. 18, 11, 17 p., e0293063.

Research output: Contribution to journal › Article › peer-review

Open Access

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24 Downloads (Pure)

Diabetic macular edema and diode subthreshold micropulse laser: A randomized double-masked noninferiority clinical trial

Lois, N., Campbell, C., Waugh, N., Azuara-Blanco, A., Maredza, M., Mistry, H., McAuley, D., Acharya, N., Aslam, T. M., Bailey, C., Chong, V., Downey, L., Eleftheriadis, H., Fatum, S., George, S., Ghanchi, F., Groppe, M., Hamilton, R., Menon, G. & Saad, A. & 7 others, Sivaprasad, S., Shiew, M., Steel, D. H., Talks, J. S., Doherty, P., McDowell, C. & Clarke, M., Jan 2023, In: Ophthalmology. 130, 1, p. 14-27 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

23 Citations (Scopus)

53 Downloads (Pure)

Do critical illness survivors with multimorbidity need a different model of care?

Stewart, J., Bradley, J., Smith, S., McPeake, J., Walsh, T., Haines, K., Leggett, N., Hart, N. & McAuley, D., 08 Dec 2023, In: Critical Care. 27, 1, p. 485 11 p., 485.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

9 Citations (Scopus)

41 Downloads (Pure)

Driving pressure: what is the harm?

Millar, J. E., McAuley, D. F. & Marini, J. J., 01 Jul 2023, In: Critical Care Medicine. 51, 7, p. 967-970 4 p.

Research output: Contribution to journal › Editorial › peer-review

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial

Lawler, P. R., Derde, L. P. G., Van De Veerdonk, F. L., McVerry, B. J., Huang, D. T., Berry, L. R., Lorenzi, E., Van Kimmenade, R., Gommans, F., Vaduganathan, M., Leaf, D. E., Baron, R. M., Kim, E. Y., Frankfurter, C., Epelmaņ, S., Kwan, Y., Grieve, R., O'Neill, S., Sadique, Z. & Puskarich, M. & 60 others, Marshall, J. C., Higgins, A. M., Mouncey, P. R., Rowan, K. M., Al-Beidh, F., Annane, D., Arabi, Y. M., Au, C., Beane, A., Van Bentum-Puijk, W., Bonten, M. J. M., Bradbury, C. A., Brunkhorst, F. M., Burrell, A., Buzgau, A., Buxton, M., Cecconi, M., Cheng, A. C., Cove, M., Detry, M. A., Estcourt, L. J., Ezekowitz, J., Fitzgerald, M., Gattas, D., Godoy, L. C., Goossens, H., Haniffa, R., Harrison, D. A., Hills, T., Horvat, C. M., Ichihara, N., Lamontagne, F., Linstrum, K. M., McAuley, D. F., McGlothlin, A., McGuinness, S. P., McQuilten, Z., Murthy, S., Nichol, A. D., Owen, D. R. J., Parke, R. L., Parker, J. C., Pollock, K. M., Reyes, L. F., Saito, H., Santos, M. S., Saunders, C. T., Seymour, C. W., Shankar-Hari, M., Singh, V., Turgeon, A. F., Turner, A. M., Zarychanski, R., Green, C., Lewis, R. J., Angus, D. C., Berry, S., Gordon, A. C., McArthur, C. J. & Webb, S. A., 11 Apr 2023, In: JAMA. 329, 14, p. 1183-1196 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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34 Citations (Scopus)

49 Downloads (Pure)

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Pienkos, S. M., Moore, A. R., Guan, J., Levitt, J. E., Matthay, M. A., Baron, R. M., Conlon, J., McAuley, D. F., O’Kane, C. M. & Rogers, A. J., 28 Mar 2023, (Early online date) In: Critical Care. 27, 1, 126.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

35 Downloads (Pure)

Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS)

Mehta, P., Samanta, R. J., Wick, K., Coll, R. C., Mawhinney, T., McAleavey, P. G., Boyle, A. J., Conlon, J., Shankar-Hari, M., Rogers, A., Calfee, C. S., Matthay, M. A., Summers, C., Chambers, R. C., McAuley, D. F. & O'Kane, C. M., 26 Dec 2023, (Early online date) In: Thorax. 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

246 Downloads (Pure)

Elevated plasma Interleukin-18 identifies high-risk acute respiratory distress syndrome patients not distinguished by prior latent class analyses using traditional inflammatory cytokines: a retrospective analysis of two randomized clinical trials

Moore, A. R., Pienkos, S. M., Sinha, P., Guan, J., O'Kane, C. M., Levitt, J. E., Wilson, J. G., Shankar-Hari, M., Matthay, M. A., Calfee, C. S., Baron, R. M., McAuley, D. F. & Rogers, A. J., 01 Dec 2023, In: Critical care medicine. 51, 12, p. e269-e274 6 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

Grasselli, G., Calfee, C. S., Camporota, L., Poole, D., Amato, M. B. P., Antonelli, M., Arabi, Y. M., Baroncelli, F., Beitler, J. R., Bellani, G., Bellingan, G., Blackwood, B., Bos, L. D. J., Brochard, L., Brodie, D., Burns, K. E. A., Combes, A., D'Arrigo, S., De Backer, D. & Demoule, A. & 31 others, Einav, S., Fan, E., Ferguson, N. D., Frat, J.-P., Gattinoni, L., Guérin, C., Herridge, M. S., Hodgson, C., Hough, C. L., Jaber, S., Juffermans, N. P., Karagiannidis, C., Kesecioglu, J., Kwizera, A., Laffey, J. G., Mancebo, J., Matthay, M. A., McAuley, D. F., Mercat, A., Meyer, N. J., Moss, M., Munshi, L., Myatra, S. N., Ng Gong, M., Papazian, L., Patel, B. K., Pellegrini, M., Perner, A., Pesenti, A., Piquilloud, L. & European Society of Intensive Care Medicine Taskforce on ARDS, Jul 2023, In: Intensive Care Medicine. 49, p. 727–759

Research output: Contribution to journal › Article › peer-review

Open Access

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285 Citations (Scopus)

60 Downloads (Pure)

Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials

Saha, R., Pham, T., Sinha, P., Maddali, M. V., Bellani, G., Fan, E., Summers, C., Douiri, A., Rubenfeld, G., Calfee, C. S., Laffey, J. G., McAuley, D. F., Shankar-Hari, M., Pesenti, A., Laffey, J. G., Brochard, L., Esteban, A., Gattinoni, L., Haren, F. V. & Larsson, A. & 30 others, Ranieri, M., Rubenfeld, G., Taylor Thompson, B., Wrigge, H., Slutsky, A. S., Giacomo, B., Pham, T., Fan, E., Rios, F., Sottiaux, T., Depuydt, P., Lora, F. S., Azevedo, L. C., Bugedo, G., Qiu, H., Gonzalez, M., Silesky, J., Cerny, V., Nielsen, J., Jibaja, M., Matamis, D., Ranero, J. L., Amin, P., Hashemian, S. M., Clarkson, K., Bellani, G., Kurahashi, K., Villagomez, A., McNamee, L. & LUNG SAFE Investigators, 26 Jul 2023, (Early online date) In: Thorax. thorax-2023-220262.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Citations (Scopus)

80 Downloads (Pure)

Galectin-3 inhibition in COVID-19

Reddy, K., Nichol, A. D. & McAuley, D. F., 15 Jan 2023, In: American Journal of Respiratory and Critical Care Medicine. 207, 2, p. 118-120

Research output: Contribution to journal › Editorial › peer-review

Open Access

File

5 Citations (Scopus)

27 Downloads (Pure)

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Pairo-Castineira, E., Bretherick, A. D., Rawlik, K., Qi, T., Wu, Y., Nassiri, I., McConkey, G. A., Zechner, M., Klaric, L., Griffiths, F., Oosthuyzen, W., Kousathanas, A., Richmond, A., Millar, J., Russell, C. D., Malinauskas, T., Thwaites, R., Morrice, K., Keating, S. & Maslove, D. & 34 others, Nichol, A., Semple, M. G., Knight, J., Shankar-Hari, M., Summers, C., Hinds, C., Horby, P., Ling, L., McAuley, D., Montgomery, H., Openshaw, P. J. M., Begg, C., Walsh, T., Tenesa, A., Flores, C., Riancho, J. A., Rojas-Martinez, A., Lapunzina, P., GenOMICC Investigators, SCOURGE Consortium, ISARICC Investigators, 23andMe COVID-19 Team, Yang, J., Ponting, C. P., Wilson, J. F., Vitart, V., Abedalthagafi, M., Luchessi, A. D., Parra, E. J., Cruz, R., Carracedo, A., Fawkes, A., Murphy, L. & Rowan, K., 25 May 2023, In: Nature. 617, 7962, p. 764-768 5 p.

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Heterogeneity of surrogate outcome measures used in critical care studies: a systematic review

Verghis, R., Blackwood, B., McDowell, C., Toner, P., Hadfield, D., Gordon, A. C., Clarke, M. & McAuley, D., Jun 2023, In: Clinical Trials. 20, 3, p. 307-318 12 p.

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Inhibition of bradykinin in SARS-CoV-2 infection: a randomised, double-blind trial of icatibant compared with placebo (ICASARS)

Bailey, M., Linden, D., Earley, O., Guo Parke, H., McAuley, D. F., Peto, T., Taggart, C. & Kidney, J., 30 Nov 2023, In: BMJ Open. 13, 11, e074726.

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Intravenous vitamin C for patients hospitalized with COVID-19. Two harmonized randomized clinical trials

Adhikari, N. K. J., Hashmi, M., Tirupakuzhi Vijayaraghavan, B. K., Haniffa, R., Beane, A., Webb, S. A., Angus, D. C., Gordon, A. C., Cook, D. J., Guyatt, G. H., Berry, L. R., Lorenzi, E., Mouncey, P. R., Au, C., Pinto, R., Ménard, J., Sprague, S., Masse, M.-H., Huang, D. T. & Heyland, D. K. & 31 others, Nichol, A. D., McArthur, C. J., de Man, A., Al-Beidh, F., Annane, D., Anstey, M., Arabi, Y. M., Battista, M.-C., Berry, S., Bhimani, Z., Bonten, M. J. M., Bradbury, C. A., Brant, E. B., Brunkhorst, F. M., Burrell, A., Buxton, M., Cecconi, M., Cheng, A. C., Cohen, D., Cove, M. E., Day, A. G., Derde, L. P. G., Detry, M. A., Estcourt, L. J., Fagbodun, E. O., Fitzgerald, M., Goossens, H., Green, C., Higgins, A. M., McAuley, D. F. & LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, 25 Oct 2023, (Early online date) In: JAMA: Journal of the American Medical Association. 15 p.

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Landiolol and organ failure in patients with septic shock. The STRESS-L randomized clinical trial

Whitehouse, T., Hossain, A., Perkins, G. D., Gordon, A. C., Bion, J., Young, D., McAuley, D., Singer, M., Lord, J., Gates, S., Veenith, T., MacCallum, N. S., Yeung, J., Innes, R., Welters, I., Boota, N., Skilton, E., Ghuman, B., Hill, M. & Regan, S. E. & 3 others, Mistry, D., Lall, R. & STRESS-L Collaborators, 25 Oct 2023, (Early online date) In: JAMA: Journal of the American Medical Association. 330, 17, p. 1641 1 p.

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Long-term (180-day) outcomes in critically ill patients with COVID-19 in the REMAP-CAP randomized clinical trial

Higgins, A. M., Berry, L. R., Lorenzi, E., Murthy, S., McQuilten, Z., Mouncey, P. R., Al-Beidh, F., Annane, D., Arabi, Y. M., Beane, A., Van Bentum-Puijk, W., Bhimani, Z., Bonten, M. J. M., Bradbury, C. A., Brunkhorst, F. M., Burrell, A., Buzgau, A., Buxton, M., Charles, W. N. & Cove, M. & 30 others, Detry, M. A., Estcourt, L. J., Fagbodun, E. O., Fitzgerald, M., Girard, T. D., Goligher, E. C., Goossens, H., Haniffa, R., Hills, T., Horvat, C. M., Huang, D. T., Ichihara, N., Lamontagne, F., Marshall, J. C., McAuley, D. F., McGlothlin, A., McGuinness, S. P., McVerry, B. J., Neal, M. D., Nichol, A. D., Parke, R. L., Parker, J. C., Parry-Billings, K., Peters, S. E. C., Reyes, L. F., Rowan, K. M., Saito, H., Santos, M. S., Saunders, C. T. & Serpa-Neto, A., 03 Jan 2023, In: JAMA. 329, 1, p. 39-51 13 p.

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81 Citations (Scopus)

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Danny McAuley

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