Projects per year
Work within my team at Queen’s University Belfast lies in translational research. Our endeavours in this landscape centre around the delivery of compute capabilities to handle the ‘big data’ era and delivery analytics bespoke to scientific discovery. Key to driving discovery in this space are intelligent software capabilities and integrative frameworks in which to embed information allowing data persistent and analytic proficiencies. These endeavours are becoming paramount in all modern research programs and central to multi-stakeholder projects around data transparency and ownership. Integromic software developed from my group is now being applied in multi-centre projects on large collaborative initiatives. These ongoing programs and research interests are becoming central frameworks for much of the efforts within QUB and UK wide hubs.
We work in a range of bioinformatic areas that integrate information to common platform spanning concepts from evolutionary algorithms and natural language processing to phylogenetics and evolution. This has recently culminated in the QUB spin out company Sonrai Analytics, an integrative software solution for modern day ‘big data’.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Dive into details
Select a country/territory to view shared publications and projects
02/06/2019 → …
05/11/2018 → …
Evolutionary genetic algorithm identifies IL2RB as a potential predictive biomarker for immune-checkpoint therapy in colorectal cancerAlderdice, M., Craig, S. G., Humphries, M. P., Gilmore, A., Johnston, N., Bingham, V., Coyle, V., Senevirathne, S., Longley, D. B., Loughrey, M. B., McQuaid, S., James, J. A., Salto-Tellez, M., Lawler, M. & McArt, D. G., 01 Jun 2021, In: NAR Genomics and Bioinformatics. 3, 2, p. lqab016
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile11 Downloads (Pure)
Bibby, B. A. S., Thiruthaneeswaran, N., Yang, L., Pereira, R. R., More, E., McArt, D. G., O'Reilly, P., Bristow, R. G., Williams, K. J., Choudhury, A. & West, C. M. L., 01 Jul 2021, In: BMC Urology. 21, 1, p. 96
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile8 Downloads (Pure)
Stupnikov, A., McInerney, C. E., Savage, K. I., McIntosh, S. A., Emmert-Streib, F., Kennedy, R., Salto-Tellez, M., Prise, K. M. & McArt, D. G., 26 May 2021, In: Computational and Structural Biotechnology Journal. 19, p. 3470-3481 12 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile14 Downloads (Pure)
Turner, B. L., Senevirathne, S., Kilgour, K., McArt, D., Biggs, M., Menegatti, S. & Daniele, M. A., 08 Jul 2021, (Early online date) In: Advanced Healthcare Materials.
Research output: Contribution to journal › Article › peer-review
Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxiaCraig, S. G., Humphries, M. P., Alderdice, M., Bingham, V., Richman, S. D., Loughrey, M. B., Coleman, H. G., Viratham-Pulsawatdi, A., McCombe, K., Murray, G. I., Blake, A., Domingo, E., Robineau, J., Brown, L., Fisher, D., Seymour, M. T., Quirke, P., Bankhead, P., McQuaid, S., Lawler, M. & 4 others, , 13 Oct 2020, In: British Journal of Cancer. 123, 8, p. 1280–1288
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile
Press / Media
Stephanie Craig, Matthew Humphries, Matthew Alderdice, Victoria Bingham, Susan Richman, Maurice Loughrey, Helen Coleman, Amélie Viratham Pulsawatdi, Kris McCombe, Murray Graeme, Andrew Blake, Enric Domingo, James Robineau, Louise Brown, David Fisher, Matt Seymour, Phil Quirke, Peter Bankhead, Stephen McQuaid, Mark Lawler, Darragh McArt, Tim Maughan, Jacqueline James & Manuel Salto-Tellez
1 item of Media coverage