If you made any changes in Pure these will be visible here soon.

Personal profile

Research Statement

Work within my team at Queen’s University Belfast lies in translational research. Our endeavours in this landscape centre around the delivery of compute capabilities to handle the ‘big data’ era and delivery analytics bespoke to scientific discovery. Key to driving discovery in this space are intelligent software capabilities and integrative frameworks in which to embed information allowing data persistent and analytic proficiencies. These endeavours are becoming paramount in all modern research programs and central to multi-stakeholder projects around data transparency and ownership. Integromic software developed from my group is now being applied in multi-centre projects on large collaborative initiatives. These ongoing programs and research interests are becoming central frameworks for much of the efforts within QUB and UK wide hubs.

Research Interests

We work in a range of bioinformatic areas that integrate information to common platform spanning concepts from evolutionary algorithms and natural language processing to phylogenetics and evolution. This has recently culminated in the QUB spin out company Sonrai Analytics, an integrative software solution for modern day ‘big data’.

Fingerprint Dive into the research topics where Darragh McArt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 83 Similar Profiles
Colorectal Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Genes Medicine & Life Sciences
Adjuvant Chemotherapy Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2019

Research Output 2009 2019

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In : Journal of Oncology.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
Triple Negative Breast Neoplasms
Biomarkers
Neoplasms
DNA Repair

A Workbench using Evolutionary Genetic Algorithms for analyzing association in TCGA Data

Gilmore, A., Alderdice, M., Savage, K., O’Reilly, P. G., Roddy, A., Dunne, P., Lawler, M., McDade, S., Waugh, D. & McArt, D., 13 Feb 2019, In : Cancer Research.

Research output: Contribution to journalArticle

Atlases
Genome
Neoplasms
Breast Neoplasms
RNA Sequence Analysis

Defining the molecular evolution of extrauterine high grade serous carcinoma

Beirne, J. P., McArt, D. G., Roddy, A., McDermott, C., Ferris, J., Buckley, N. E., Coulter, P., McCabe, N., Eddie, S. L., Dunne, P. D., O'Reilly, P., Gilmore, A., Feeney, L., Ewing, D. L., Drapkin, R. I., Salto-Tellez, M., Kennedy, R. D., Harley, I. J. G., McCluggage, W. G. & Mullan, P. B., 04 Sep 2019, In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Molecular Evolution
Carcinoma
Fallopian Tubes
Carcinoma in Situ
Epithelium
Open Access
File
cancer
neoplasms
tumor
Neoplasms
trajectory
4 Citations (Scopus)

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer

Humphries, M., Hynes, S., Bingham, V., Cougot, D., James, J., Patel-Socha, F., Parkes, E., Blayney, J., O'Rorke, M., Irwin, G., McArt, D., Kennedy, R., Mullan, P., McQuaid, S., Salto-Tellez, M. & Buckley, N. E., 17 Dec 2018, In : Journal of Oncology. 2018, 14 p., 2937012.

Research output: Contribution to journalArticle

Open Access
File
Biomarkers
Pathology
Breast Neoplasms
Triple Negative Breast Neoplasms
Drug Therapy